Project

Illumina Body Map 2

Navigation
Downloads

Results for EN2_GBX2_LBX2

Z-value: 0.71

Motif logo

Transcription factors associated with EN2_GBX2_LBX2

Gene Symbol Gene ID Gene Info
ENSG00000164778.4 engrailed homeobox 2
ENSG00000168505.6 gastrulation brain homeobox 2
ENSG00000179528.11 ladybird homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LBX2hg19_v2_chr2_-_74730087_74730111-0.232.1e-01Click!
EN2hg19_v2_chr7_+_155250824_155250824-0.183.2e-01Click!
GBX2hg19_v2_chr2_-_237076992_237077012-0.125.1e-01Click!

Activity profile of EN2_GBX2_LBX2 motif

Sorted Z-values of EN2_GBX2_LBX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_36245561 5.31 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_76732928 2.15 ENST00000589768.1
cytohesin 1
chrX_-_21676442 2.07 ENST00000379499.2
kelch-like family member 34
chr15_+_58430368 1.92 ENST00000558772.1
ENST00000219919.4
aquaporin 9
chr15_+_58430567 1.80 ENST00000536493.1
aquaporin 9
chr7_+_77428066 1.78 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr7_+_77428149 1.67 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr18_+_59000815 1.47 ENST00000262717.4
cadherin 20, type 2
chr12_+_81110684 1.43 ENST00000228644.3
myogenic factor 5
chr7_-_77427676 1.31 ENST00000257663.3
transmembrane protein 60
chr12_-_89746264 1.19 ENST00000548755.1
dual specificity phosphatase 6
chrX_+_135730297 1.16 ENST00000370629.2
CD40 ligand
chr9_+_1050331 1.10 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
doublesex and mab-3 related transcription factor 2
chr12_-_89746173 1.05 ENST00000308385.6
dual specificity phosphatase 6
chr2_-_224467002 0.96 ENST00000421386.1
ENST00000433889.1
secretogranin II
chr3_+_111718173 0.96 ENST00000494932.1
transgelin 3
chr3_+_111718036 0.91 ENST00000455401.2
transgelin 3
chr6_-_32157947 0.91 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr14_+_22992573 0.89 ENST00000390516.1
T cell receptor alpha joining 21
chr17_-_38928414 0.87 ENST00000335552.4
keratin 26
chr6_-_26199471 0.84 ENST00000341023.1
histone cluster 1, H2ad
chr3_+_111717511 0.82 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr3_+_111717600 0.78 ENST00000273368.4
transgelin 3
chr12_-_56694083 0.78 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
citrate synthase
chr15_-_55562451 0.76 ENST00000568803.1
RAB27A, member RAS oncogene family
chrX_-_18690210 0.76 ENST00000379984.3
retinoschisin 1
chr2_-_224467093 0.75 ENST00000305409.2
secretogranin II
chr12_-_56693758 0.73 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
citrate synthase
chr14_+_32798547 0.73 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr14_+_22739823 0.72 ENST00000390464.2
T cell receptor alpha variable 38-1
chr17_+_18086392 0.70 ENST00000541285.1
alkB, alkylation repair homolog 5 (E. coli)
chr2_+_17997763 0.70 ENST00000281047.3
mesogenin 1
chr13_-_41593425 0.70 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr5_+_66300464 0.62 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr1_-_157746909 0.61 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
Fc receptor-like 2
chr17_-_39203519 0.61 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr2_-_77749446 0.58 ENST00000409911.1
leucine rich repeat transmembrane neuronal 4
chr2_-_77749474 0.57 ENST00000409093.1
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr4_+_105828492 0.56 ENST00000506148.1
RP11-556I14.1
chr14_+_32798462 0.55 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr2_-_77749336 0.54 ENST00000409282.1
leucine rich repeat transmembrane neuronal 4
chr16_+_69345243 0.53 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr15_-_55562479 0.53 ENST00000564609.1
RAB27A, member RAS oncogene family
chr15_-_55563072 0.52 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr2_-_61697862 0.51 ENST00000398571.2
ubiquitin specific peptidase 34
chr3_-_27764190 0.51 ENST00000537516.1
eomesodermin
chr12_-_56694142 0.50 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr11_-_33913708 0.49 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr11_-_18211042 0.47 ENST00000527671.1
Uncharacterized protein
chr17_-_39191107 0.46 ENST00000344363.5
keratin associated protein 1-3
chr12_-_14133053 0.43 ENST00000609686.1
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr1_+_179923873 0.43 ENST00000367607.3
ENST00000491495.2
centrosomal protein 350kDa
chr4_+_183065793 0.43 ENST00000512480.1
teneurin transmembrane protein 3
chr1_-_156399184 0.43 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
chromosome 1 open reading frame 61
chr15_-_55562582 0.41 ENST00000396307.2
RAB27A, member RAS oncogene family
chr4_-_57547870 0.40 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOP homeobox
chr4_-_39979576 0.40 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chrX_+_130192318 0.39 ENST00000370922.1
Rho GTPase activating protein 36
chr5_+_176811431 0.39 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chrM_+_12331 0.38 ENST00000361567.2
mitochondrially encoded NADH dehydrogenase 5
chr5_-_82969363 0.38 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr6_+_31783291 0.37 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr6_+_43968306 0.36 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr9_+_12693336 0.36 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr5_+_66300446 0.36 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr2_-_77749387 0.35 ENST00000409884.1
leucine rich repeat transmembrane neuronal 4
chr7_-_111424506 0.35 ENST00000450156.1
ENST00000494651.2
dedicator of cytokinesis 4
chr6_+_26199737 0.35 ENST00000359985.1
histone cluster 1, H2bf
chr17_-_9929581 0.35 ENST00000437099.2
ENST00000396115.2
growth arrest-specific 7
chr1_-_190446759 0.34 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_57547454 0.34 ENST00000556376.2
HOP homeobox
chr15_+_76629064 0.34 ENST00000290759.4
ISL LIM homeobox 2
chr1_-_151762900 0.34 ENST00000440583.2
tudor and KH domain containing
chrX_+_134654540 0.33 ENST00000370752.4
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr6_+_111408698 0.33 ENST00000368851.5
solute carrier family 16 (aromatic amino acid transporter), member 10
chr6_+_49467671 0.33 ENST00000371197.4
ENST00000545705.1
glycine-N-acyltransferase-like 3
chr12_+_28410128 0.32 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chr5_-_82969405 0.31 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr21_-_32253874 0.31 ENST00000332378.4
keratin associated protein 11-1
chr6_-_18264406 0.30 ENST00000515742.1
DEK oncogene
chr21_+_31812597 0.30 ENST00000334067.3
keratin associated protein 15-1
chrX_+_123097014 0.30 ENST00000394478.1
stromal antigen 2
chr16_+_53133070 0.29 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr3_+_35685113 0.29 ENST00000419330.1
cAMP-regulated phosphoprotein, 21kDa
chr6_+_34204642 0.29 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr8_+_38831683 0.29 ENST00000302495.4
HtrA serine peptidase 4
chr3_+_35722487 0.28 ENST00000441454.1
cAMP-regulated phosphoprotein, 21kDa
chr7_-_92777606 0.28 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr3_+_167453493 0.27 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr5_-_95297534 0.27 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr5_-_95297678 0.27 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr6_+_130339710 0.27 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr3_+_115342349 0.26 ENST00000393780.3
growth associated protein 43
chr1_+_145507587 0.26 ENST00000330165.8
ENST00000369307.3
RNA binding motif protein 8A
chr6_-_139613269 0.25 ENST00000358430.3
taxilin beta
chr8_-_1922789 0.25 ENST00000521498.1
RP11-439C15.4
chr15_+_48483736 0.25 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chrX_+_591524 0.25 ENST00000554971.1
ENST00000381575.1
short stature homeobox
chr8_-_25281747 0.24 ENST00000421054.2
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr18_-_53019208 0.24 ENST00000562607.1
transcription factor 4
chr1_-_152131703 0.24 ENST00000316073.3
repetin
chr4_-_143226979 0.23 ENST00000514525.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr9_+_136501478 0.23 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr7_-_111424462 0.23 ENST00000437129.1
dedicator of cytokinesis 4
chr15_+_96904487 0.23 ENST00000600790.1
Uncharacterized protein
chr6_-_111927062 0.23 ENST00000359831.4
TRAF3 interacting protein 2
chr6_+_140175987 0.22 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
chr4_+_144354644 0.22 ENST00000512843.1
GRB2-associated binding protein 1
chr4_-_143227088 0.22 ENST00000511838.1
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr4_-_120243545 0.22 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr3_-_52090461 0.21 ENST00000296483.6
ENST00000495880.1
dual specificity phosphatase 7
chr3_+_152879985 0.21 ENST00000323534.2
RAP2B, member of RAS oncogene family
chr21_-_43816052 0.21 ENST00000398405.1
transmembrane protease, serine 3
chr3_+_35722424 0.21 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chr4_-_174255400 0.21 ENST00000506267.1
high mobility group box 2
chr20_-_45976816 0.21 ENST00000441977.1
zinc finger, MYND-type containing 8
chr12_+_7013897 0.21 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr12_+_7014064 0.20 ENST00000443597.2
leucine rich repeat containing 23
chr3_-_157217328 0.20 ENST00000392832.2
ENST00000543418.1
ventricular zone expressed PH domain-containing 1
chr6_+_135502501 0.20 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr17_-_10017864 0.20 ENST00000323816.4
growth arrest-specific 7
chrX_+_129473916 0.20 ENST00000545805.1
ENST00000543953.1
ENST00000218197.5
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr3_-_119813264 0.19 ENST00000264235.8
glycogen synthase kinase 3 beta
chr11_-_40315640 0.19 ENST00000278198.2
leucine rich repeat containing 4C
chr11_-_124294789 0.19 ENST00000356130.3
olfactory receptor, family 8, subfamily B, member 4
chr18_+_32173276 0.19 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr1_-_151762943 0.18 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
tudor and KH domain containing
chr19_-_14640005 0.18 ENST00000596853.1
ENST00000596075.1
ENST00000595992.1
ENST00000396969.4
ENST00000601533.1
ENST00000598692.1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr4_-_89205879 0.18 ENST00000608933.1
ENST00000315194.4
ENST00000514204.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr12_-_53171128 0.18 ENST00000332411.2
keratin 76
chr19_-_40931891 0.17 ENST00000357949.4
SERTA domain containing 1
chr4_-_89205705 0.17 ENST00000295908.7
ENST00000510548.2
ENST00000508256.1
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr17_-_9694614 0.17 ENST00000330255.5
ENST00000571134.1
dehydrogenase/reductase (SDR family) member 7C
chr7_+_74072288 0.17 ENST00000443166.1
general transcription factor IIi
chr18_-_44181442 0.17 ENST00000398722.4
lipoxygenase homology domains 1
chr14_-_73360796 0.17 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
D4, zinc and double PHD fingers, family 3
chr6_-_26199499 0.16 ENST00000377831.5
histone cluster 1, H3d
chr12_-_52828147 0.16 ENST00000252245.5
keratin 75
chr2_+_65216462 0.16 ENST00000234256.3
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr17_+_7792101 0.16 ENST00000358181.4
ENST00000330494.7
chromodomain helicase DNA binding protein 3
chr19_+_51728316 0.15 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33 molecule
chr1_-_17766198 0.15 ENST00000375436.4
regulator of chromosome condensation 2
chr1_+_101003687 0.14 ENST00000315033.4
G protein-coupled receptor 88
chr17_-_48785216 0.14 ENST00000285243.6
ankyrin repeat domain 40
chr3_+_133292759 0.14 ENST00000431519.2
CDV3 homolog (mouse)
chr5_+_179159813 0.14 ENST00000292599.3
mastermind-like 1 (Drosophila)
chr15_-_98836406 0.13 ENST00000560360.1
CTD-2544M6.1
chr20_+_42523336 0.13 ENST00000428529.1
RP5-1030M6.3
chr7_+_18329712 0.13 ENST00000433709.2
histone deacetylase 9
chr17_+_72931876 0.13 ENST00000328801.4
otopetrin 3
chr14_-_78083112 0.13 ENST00000216484.2
serine palmitoyltransferase, long chain base subunit 2
chr14_+_60386853 0.13 ENST00000570145.1
leucine rich repeat containing 9
chrX_+_154444643 0.12 ENST00000286428.5
von Hippel-Lindau binding protein 1
chr2_-_242089677 0.12 ENST00000405260.1
PAS domain containing serine/threonine kinase
chr6_-_26250835 0.12 ENST00000446824.2
histone cluster 1, H3f
chr17_-_38911580 0.12 ENST00000312150.4
keratin 25
chr10_-_56560939 0.12 ENST00000373955.1
protocadherin-related 15
chr20_+_18447771 0.12 ENST00000377603.4
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr19_+_48949030 0.11 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr14_+_72052983 0.11 ENST00000358550.2
signal-induced proliferation-associated 1 like 1
chr12_+_64798826 0.11 ENST00000540203.1
exportin, tRNA
chr2_+_149402989 0.11 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr3_+_130162328 0.11 ENST00000512482.1
collagen, type VI, alpha 5
chr5_+_148737562 0.11 ENST00000274569.4
prenylcysteine oxidase 1 like
chr15_-_64673630 0.10 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr3_-_157221380 0.10 ENST00000468233.1
ventricular zone expressed PH domain-containing 1
chr6_-_116833500 0.10 ENST00000356128.4
trafficking protein particle complex 3-like
chr3_+_172468749 0.10 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
epithelial cell transforming sequence 2 oncogene
chr1_-_23670752 0.10 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
heterogeneous nuclear ribonucleoprotein R
chr18_+_32402321 0.10 ENST00000587723.1
dystrobrevin, alpha
chr7_+_138145076 0.10 ENST00000343526.4
tripartite motif containing 24
chr17_-_74163159 0.09 ENST00000591615.1
ring finger protein 157
chr10_-_56561022 0.09 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
protocadherin-related 15
chr19_-_19302931 0.09 ENST00000444486.3
ENST00000514819.3
ENST00000585679.1
ENST00000162023.5
MEF2BNB-MEF2B readthrough
MEF2B neighbor
myocyte enhancer factor 2B
chr15_-_64673665 0.09 ENST00000300035.4
KIAA0101
chr9_-_136933615 0.09 ENST00000371834.2
bromodomain containing 3
chr6_-_161695042 0.09 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
1-acylglycerol-3-phosphate O-acyltransferase 4
chr18_+_55888767 0.09 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr11_+_57435441 0.09 ENST00000528177.1
zinc finger, DHHC-type containing 5
chr6_-_31782813 0.09 ENST00000375654.4
heat shock 70kDa protein 1-like
chr20_-_50722183 0.09 ENST00000371523.4
ZFP64 zinc finger protein
chr12_-_10955226 0.09 ENST00000240687.2
taste receptor, type 2, member 7
chr11_+_75526212 0.09 ENST00000356136.3
UV radiation resistance associated
chr4_+_105828537 0.09 ENST00000515649.1
RP11-556I14.1
chr4_-_174256276 0.09 ENST00000296503.5
high mobility group box 2
chr16_+_9185450 0.08 ENST00000327827.7
chromosome 16 open reading frame 72
chr19_-_59084647 0.08 ENST00000594234.1
ENST00000596039.1
myeloid zinc finger 1
chr6_-_161695074 0.08 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr1_+_110881945 0.08 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chrX_+_47077680 0.08 ENST00000522883.1
cyclin-dependent kinase 16
chr19_+_14640372 0.08 ENST00000215567.5
ENST00000598298.1
ENST00000596073.1
ENST00000600083.1
ENST00000436007.2
trans-2,3-enoyl-CoA reductase
chr17_-_8093471 0.08 ENST00000389017.4
chromosome 17 open reading frame 59
chr10_+_99205894 0.08 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr1_-_23670813 0.07 ENST00000374612.1
heterogeneous nuclear ribonucleoprotein R
chr7_+_1272522 0.07 ENST00000316333.8
UNC homeobox
chr5_+_141303461 0.07 ENST00000508751.1
KIAA0141
chr3_+_172468505 0.07 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr17_-_7307358 0.07 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr5_+_145826867 0.07 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr4_-_74486109 0.07 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6

Network of associatons between targets according to the STRING database.

First level regulatory network of EN2_GBX2_LBX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.4 2.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.3 2.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.2 0.8 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.5 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.2 1.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 1.1 GO:0061055 myotome development(GO:0061055)
0.1 0.7 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.4 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 1.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.7 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.4 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 2.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 0.3 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 1.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.1 GO:0003292 cardiac septum cell differentiation(GO:0003292) atrioventricular node cell differentiation(GO:0060922) atrioventricular node cell development(GO:0060928)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.2 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.7 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0070327 aromatic amino acid transport(GO:0015801) thyroid hormone transport(GO:0070327)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.3 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0046292 formaldehyde metabolic process(GO:0046292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.5 GO:0071547 piP-body(GO:0071547)
0.1 1.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 3.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0015254 glycerol channel activity(GO:0015254)
0.7 2.0 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.4 1.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 2.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.3 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 6.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 2.2 GO:0031489 myosin V binding(GO:0031489)
0.1 1.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.7 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 2.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 2.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 5.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)