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Illumina Body Map 2
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Results for ETV2
Z-value: 0.71
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Transcription factors associated with ETV2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV2 | hg19_v2_chr19_+_36132631_36132695 | -0.22 | 2.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.3 | GO:0070126 | mitochondrial translational termination(GO:0070126) |
| 0.3 | 2.6 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.1 | 2.5 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.6 | 2.3 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 0.2 | 2.3 | GO:0019276 | UDP-N-acetylgalactosamine metabolic process(GO:0019276) |
| 0.1 | 2.3 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.0 | 2.0 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 1.9 | GO:0071801 | regulation of podosome assembly(GO:0071801) |
| 0.1 | 1.8 | GO:0042424 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
| 0.6 | 1.7 | GO:2000705 | dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.6 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 2.4 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 2.4 | GO:0030018 | Z disc(GO:0030018) |
| 0.1 | 2.3 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.1 | 2.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 2.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 2.0 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 1.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.8 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 1.7 | GO:0031045 | dense core granule(GO:0031045) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.6 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 0.1 | 2.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.8 | 2.3 | GO:0035248 | alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248) |
| 0.2 | 2.2 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 2.2 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 2.1 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
| 0.0 | 1.9 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.1 | 1.8 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 1.8 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 1.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 3.4 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 3.1 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 2.8 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 2.3 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 1.9 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.6 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.2 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 2.1 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 1.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.7 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 1.6 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 1.6 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.2 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |