Project
Illumina Body Map 2
Navigation
Downloads
Results for FOSB
Z-value: 0.94
Motif logo
Transcription factors associated with FOSB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOSB | hg19_v2_chr19_+_45971246_45971265 | -0.30 | 9.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_35685113 Show fit | 1.97 |
ENST00000419330.1
|
cAMP-regulated phosphoprotein, 21kDa |
|
| chr11_-_10920714 Show fit | 1.88 |
ENST00000533941.1
|
CTD-2003C8.2 |
|
| chr17_+_4853442 Show fit | 1.88 |
ENST00000522301.1
|
enolase 3 (beta, muscle) |
|
| chr2_-_220173685 Show fit | 1.84 |
ENST00000423636.2
ENST00000442029.1 ENST00000412847.1 |
protein tyrosine phosphatase, receptor type, N |
|
| chr2_+_27505260 Show fit | 1.65 |
ENST00000380075.2
ENST00000296098.4 |
tripartite motif containing 54 |
|
| chr17_-_8021710 Show fit | 1.57 |
ENST00000380149.1
ENST00000448843.2 |
arachidonate lipoxygenase 3 |
|
| chr1_-_190443931 Show fit | 1.57 |
ENST00000445957.2
|
bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
|
| chr14_-_75083313 Show fit | 1.55 |
ENST00000556652.1
ENST00000555313.1 |
CTD-2207P18.2 |
|
| chr10_-_76818272 Show fit | 1.54 |
ENST00000338487.5
|
dual specificity phosphatase and pro isomerase domain containing 1 |
|
| chr11_-_64527425 Show fit | 1.52 |
ENST00000377432.3
|
phosphorylase, glycogen, muscle |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOSB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0006735 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 2.9 | GO:0060297 | regulation of sarcomere organization(GO:0060297) |
| 0.0 | 2.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 2.5 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.1 | 2.2 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.2 | 2.1 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 2.1 | GO:0033198 | response to ATP(GO:0033198) |
| 0.5 | 2.0 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.3 | 2.0 | GO:0043606 | histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606) |
| 0.5 | 1.8 | GO:1990502 | dense core granule maturation(GO:1990502) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.4 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 3.3 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 3.2 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.3 | 2.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.2 | 2.5 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.0 | 2.5 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 1.9 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.1 | 1.8 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 1.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.4 | GO:0031105 | septin complex(GO:0031105) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 2.9 | GO:0031432 | titin binding(GO:0031432) |
| 0.3 | 2.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 2.5 | GO:0047134 | protein-disulfide reductase activity(GO:0047134) |
| 0.2 | 2.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.7 | 2.0 | GO:0004397 | histidine ammonia-lyase activity(GO:0004397) |
| 0.0 | 2.0 | GO:0043531 | ADP binding(GO:0043531) |
| 0.0 | 1.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 1.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.7 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 2.2 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.9 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.7 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.4 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 1.3 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.0 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 1.9 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 1.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 1.8 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.8 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.8 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.1 | 1.4 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 1.2 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.0 | 1.2 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |