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Illumina Body Map 2

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Results for FOXA3_FOXC2

Z-value: 1.40

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Transcription factors associated with FOXA3_FOXC2

Gene Symbol Gene ID Gene Info
FOXA3
ENSG00000170608.2 forkhead box A3
FOXC2
ENSG00000176692.4 forkhead box C2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA3hg19_v2_chr19_+_46367518_463675670.648.4e-05Click!
FOXC2hg19_v2_chr16_+_86600857_866009210.134.7e-01Click!

Activity profile of FOXA3_FOXC2 motif

Sorted Z-values of FOXA3_FOXC2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_62186498 10.76 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr8_+_120079478 8.68 ENST00000332843.2
COLEC10
collectin sub-family member 10 (C-type lectin)
chr1_-_57431679 8.14 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr17_-_26695013 7.10 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr17_-_26694979 7.02 ENST00000438614.1
VTN
vitronectin
chr11_-_116708302 6.00 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr6_-_41715128 4.69 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC
progastricsin (pepsinogen C)
chr4_+_187187098 4.21 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr2_+_128175997 3.87 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr13_-_86373536 3.74 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr18_-_25616519 3.53 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_+_207277590 3.50 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr20_+_31823792 3.48 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr3_+_108855558 3.46 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
RP11-59E19.1
chr14_-_70263979 3.26 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr1_+_207277632 3.22 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr3_+_137717571 3.20 ENST00000343735.4
CLDN18
claudin 18
chr5_-_41213123 3.18 ENST00000417809.1
C6
complement component 6
chr22_+_21128167 3.09 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr14_-_36988882 3.04 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr16_-_86542652 3.02 ENST00000599749.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr17_-_19290483 2.97 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr17_-_26697304 2.96 ENST00000536498.1
VTN
vitronectin
chr10_+_71561649 2.88 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr4_+_169013666 2.76 ENST00000359299.3
ANXA10
annexin A10
chr2_+_88047606 2.57 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr7_-_107443652 2.56 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr2_+_135596180 2.55 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_+_27849378 2.51 ENST00000310791.2
REP15
RAB15 effector protein
chr14_-_94789663 2.49 ENST00000557225.1
ENST00000341584.3
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr10_+_71561630 2.43 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr14_-_38064198 2.43 ENST00000250448.2
FOXA1
forkhead box A1
chr17_-_39684550 2.40 ENST00000455635.1
ENST00000361566.3
KRT19
keratin 19
chr5_-_41213607 2.40 ENST00000337836.5
ENST00000433294.1
C6
complement component 6
chr7_+_142829162 2.31 ENST00000291009.3
PIP
prolactin-induced protein
chr20_+_31870927 2.29 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr4_-_71532207 2.27 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_+_187187337 2.26 ENST00000492972.2
F11
coagulation factor XI
chr4_+_74269956 2.26 ENST00000295897.4
ENST00000415165.2
ENST00000503124.1
ENST00000509063.1
ENST00000401494.3
ALB
albumin
chr4_+_187148556 2.24 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr3_+_137728842 2.23 ENST00000183605.5
CLDN18
claudin 18
chr16_-_86542455 2.21 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr2_+_135596106 2.20 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr12_+_59989918 2.19 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr2_+_113885138 2.16 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr4_-_71532668 2.11 ENST00000510437.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr18_+_47088401 2.09 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG
lipase, endothelial
chr15_+_69857515 2.06 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr4_-_71532601 2.05 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_+_21156915 2.00 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr10_+_71561704 1.94 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr12_-_120765565 1.93 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr5_+_147258266 1.80 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr8_+_19171128 1.79 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr4_-_71532339 1.78 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr1_+_200011711 1.77 ENST00000544748.1
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr10_-_118032697 1.76 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chrX_-_15402498 1.75 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr8_+_19171196 1.71 ENST00000518040.1
SH2D4A
SH2 domain containing 4A
chr2_-_165424973 1.69 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr10_-_118032979 1.67 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr14_+_38065052 1.67 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr16_-_48281305 1.66 ENST00000356608.2
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr9_-_95186739 1.63 ENST00000375550.4
OMD
osteomodulin
chr2_-_105030466 1.61 ENST00000449772.1
AC068535.3
AC068535.3
chr1_-_169555779 1.60 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr12_-_92539614 1.59 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr4_-_72649763 1.58 ENST00000513476.1
GC
group-specific component (vitamin D binding protein)
chr7_+_134576317 1.55 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr2_+_74120094 1.54 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2
actin, gamma 2, smooth muscle, enteric
chr10_-_81708854 1.54 ENST00000372292.3
SFTPD
surfactant protein D
chr12_-_21487829 1.53 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr7_-_81399438 1.51 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_96869165 1.49 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_57229155 1.47 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr14_-_106791536 1.46 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr21_+_17792672 1.46 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr8_+_97597148 1.45 ENST00000521590.1
SDC2
syndecan 2
chr4_+_15376165 1.45 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_+_119316721 1.43 ENST00000488919.1
ENST00000495992.1
PLA1A
phospholipase A1 member A
chr12_+_13044787 1.43 ENST00000534831.1
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr1_-_146696901 1.42 ENST00000369272.3
ENST00000441068.2
FMO5
flavin containing monooxygenase 5
chr18_-_52626622 1.40 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chrX_+_105936982 1.40 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr6_+_142623758 1.38 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126
chr2_+_7865923 1.38 ENST00000417930.1
AC092580.4
AC092580.4
chr7_-_81399355 1.34 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chrX_-_70329118 1.34 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr20_-_7921090 1.32 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr10_+_124320156 1.31 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1
deleted in malignant brain tumors 1
chr7_-_81399329 1.31 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_161123270 1.31 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr20_-_7238861 1.29 ENST00000428954.1
RP11-19D2.1
RP11-19D2.1
chr13_-_39564993 1.29 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr7_-_107643567 1.28 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr7_-_81399411 1.26 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr3_+_119316689 1.26 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr17_+_8924837 1.25 ENST00000173229.2
NTN1
netrin 1
chr21_+_17791648 1.24 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr18_+_56113488 1.24 ENST00000590797.1
RP11-1151B14.3
RP11-1151B14.3
chr6_-_161085291 1.24 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr5_+_101569696 1.22 ENST00000597120.1
AC008948.1
AC008948.1
chr7_-_107643674 1.21 ENST00000222399.6
LAMB1
laminin, beta 1
chr15_-_76352069 1.21 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr18_+_68002675 1.18 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr9_-_4299874 1.18 ENST00000381971.3
ENST00000477901.1
GLIS3
GLIS family zinc finger 3
chr1_-_169555709 1.17 ENST00000546081.1
F5
coagulation factor V (proaccelerin, labile factor)
chr6_+_44310376 1.17 ENST00000515220.1
ENST00000323108.8
SPATS1
spermatogenesis associated, serine-rich 1
chr21_+_17791838 1.16 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr12_-_21927736 1.15 ENST00000240662.2
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr10_+_71562180 1.15 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr3_+_132316081 1.14 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr14_-_25479811 1.14 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr3_+_114012819 1.13 ENST00000383671.3
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr2_+_171640291 1.12 ENST00000409885.1
ERICH2
glutamate-rich 2
chr7_+_134464414 1.11 ENST00000361901.2
CALD1
caldesmon 1
chr11_-_58378759 1.11 ENST00000601906.1
AP001350.1
Uncharacterized protein
chr7_-_81399678 1.10 ENST00000412881.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_58430368 1.10 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr14_-_36990354 1.09 ENST00000518149.1
NKX2-1
NK2 homeobox 1
chr15_+_58430567 1.07 ENST00000536493.1
AQP9
aquaporin 9
chr11_-_108464465 1.07 ENST00000525344.1
EXPH5
exophilin 5
chr15_+_69854027 1.07 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr7_-_81399287 1.06 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_-_15038779 1.06 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr5_-_137674000 1.06 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr16_-_48281444 1.06 ENST00000537808.1
ENST00000569991.1
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr14_+_38033252 1.06 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr6_+_139135648 1.05 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr2_-_188312971 1.05 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr4_-_103266626 1.04 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr11_-_108464321 1.03 ENST00000265843.4
EXPH5
exophilin 5
chr12_+_59989791 1.00 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr20_+_45338126 1.00 ENST00000359271.2
SLC2A10
solute carrier family 2 (facilitated glucose transporter), member 10
chr12_-_21928515 0.98 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chrX_+_135614293 0.97 ENST00000370634.3
VGLL1
vestigial like 1 (Drosophila)
chr4_-_186696636 0.94 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr2_-_21266935 0.93 ENST00000233242.1
APOB
apolipoprotein B
chr4_-_152149033 0.93 ENST00000514152.1
SH3D19
SH3 domain containing 19
chr4_-_186696561 0.92 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chrX_+_135730297 0.92 ENST00000370629.2
CD40LG
CD40 ligand
chr1_-_177939041 0.92 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr7_+_134576151 0.91 ENST00000393118.2
CALD1
caldesmon 1
chr2_-_87248975 0.90 ENST00000409310.2
ENST00000355705.3
PLGLB1
plasminogen-like B1
chr5_-_115872124 0.89 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr4_-_186696425 0.89 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr10_+_124320195 0.89 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr11_-_57158109 0.88 ENST00000525955.1
ENST00000533605.1
ENST00000311862.5
PRG2
proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
chr6_+_44310421 0.88 ENST00000288390.2
SPATS1
spermatogenesis associated, serine-rich 1
chr3_+_177159695 0.87 ENST00000442937.1
LINC00578
long intergenic non-protein coding RNA 578
chr12_-_7596735 0.87 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr21_-_43786634 0.87 ENST00000291527.2
TFF1
trefoil factor 1
chr6_-_159466136 0.87 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr17_-_66951474 0.86 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr12_-_102591604 0.85 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr4_+_15341442 0.84 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr17_-_38020392 0.84 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr7_-_81399744 0.82 ENST00000421558.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr1_+_74701062 0.81 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr7_+_134430212 0.81 ENST00000436461.2
CALD1
caldesmon 1
chr2_-_180427304 0.79 ENST00000336917.5
ZNF385B
zinc finger protein 385B
chr19_-_47157914 0.79 ENST00000300875.4
DACT3
dishevelled-binding antagonist of beta-catenin 3
chr7_+_73242490 0.78 ENST00000431918.1
CLDN4
claudin 4
chr4_+_75174180 0.74 ENST00000413830.1
EPGN
epithelial mitogen
chr17_-_77967433 0.73 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr2_-_21266816 0.73 ENST00000399256.4
APOB
apolipoprotein B
chr17_-_38020379 0.73 ENST00000351680.3
ENST00000346243.3
ENST00000350532.3
ENST00000467757.1
ENST00000439016.2
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr14_+_37126765 0.72 ENST00000402703.2
PAX9
paired box 9
chr11_-_102401469 0.71 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_-_208030647 0.71 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr3_+_177159744 0.71 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr15_+_75940218 0.70 ENST00000308527.5
SNX33
sorting nexin 33
chr16_+_20775358 0.69 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr7_+_134464376 0.68 ENST00000454108.1
ENST00000361675.2
CALD1
caldesmon 1
chr1_-_178840157 0.68 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr3_+_142315225 0.68 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr2_+_169659121 0.67 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr17_+_7487146 0.67 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr14_-_104408032 0.65 ENST00000455348.2
RD3L
retinal degeneration 3-like
chr4_-_186696515 0.65 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chrX_-_101410762 0.64 ENST00000543160.1
ENST00000333643.3
BEX5
brain expressed, X-linked 5
chr8_+_55528627 0.64 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr1_+_115642293 0.64 ENST00000448680.1
RP4-666F24.3
RP4-666F24.3
chr7_-_117512264 0.63 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr6_-_112575912 0.63 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr11_-_115375107 0.63 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr14_+_23299088 0.63 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52
mitochondrial ribosomal protein L52
chr6_+_122793058 0.63 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr6_-_112575838 0.62 ENST00000455073.1
LAMA4
laminin, alpha 4
chr6_-_25830785 0.61 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr10_+_75668916 0.61 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr20_+_9049303 0.60 ENST00000407043.2
ENST00000441846.1
PLCB4
phospholipase C, beta 4
chr6_-_112575758 0.60 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr8_+_75736761 0.60 ENST00000260113.2
PI15
peptidase inhibitor 15
chr6_+_21666633 0.59 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr2_+_169658928 0.59 ENST00000317647.7
ENST00000445023.2
NOSTRIN
nitric oxide synthase trafficking
chr3_-_116163830 0.58 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr1_+_214163033 0.58 ENST00000607425.1
PROX1
prospero homeobox 1
chr9_-_70490107 0.57 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5
COBW domain containing 5
chr6_+_10528560 0.57 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 10.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
1.8 10.8 GO:0010193 response to ozone(GO:0010193)
1.5 6.0 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
1.1 5.6 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
1.0 3.9 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.9 3.5 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.8 2.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.8 4.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.8 2.3 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.7 4.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.7 6.7 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.6 4.5 GO:0008218 bioluminescence(GO:0008218)
0.6 8.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 3.7 GO:0060005 vestibular reflex(GO:0060005)
0.6 10.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 5.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.5 8.7 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 2.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.5 2.5 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 3.9 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.5 2.8 GO:0032571 response to vitamin K(GO:0032571)
0.4 8.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 3.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.4 1.5 GO:0009956 radial pattern formation(GO:0009956)
0.4 2.2 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.3 4.1 GO:0021759 globus pallidus development(GO:0021759)
0.3 3.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3 3.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 2.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.5 GO:0090131 mesenchyme migration(GO:0090131)
0.2 2.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.9 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 2.3 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 0.9 GO:0002215 defense response to nematode(GO:0002215)
0.2 3.0 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.7 GO:0006642 triglyceride mobilization(GO:0006642)
0.2 0.6 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.2 3.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 1.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 2.6 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.2 0.5 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.6 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.3 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 8.4 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 2.7 GO:0015865 purine nucleotide transport(GO:0015865)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.9 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 2.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 1.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.6 GO:0051958 methotrexate transport(GO:0051958)
0.1 4.9 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0021934 medulla oblongata development(GO:0021550) hindbrain tangential cell migration(GO:0021934) lateral line system development(GO:0048925)
0.1 1.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 1.2 GO:0042908 xenobiotic transport(GO:0042908)
0.1 4.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 1.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.2 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.1 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 1.0 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 2.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 0.5 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 1.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 1.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 2.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 1.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.1 1.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 1.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 1.6 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 2.5 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.1 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.4 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 2.4 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 2.5 GO:0033572 transferrin transport(GO:0033572)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 1.6 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 1.1 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.7 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0061030 axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.6 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.9 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 1.0 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.9 GO:0010039 response to iron ion(GO:0010039)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.3 GO:0019532 oxalate transport(GO:0019532)
0.0 1.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.3 GO:0060347 heart trabecula formation(GO:0060347)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.2 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.7 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 1.5 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 1.5 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.1 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.4 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0006275 regulation of DNA replication(GO:0006275)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 10.0 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
2.1 8.4 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
2.0 6.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.4 13.7 GO:0005579 membrane attack complex(GO:0005579)
0.8 2.5 GO:0043257 laminin-8 complex(GO:0043257)
0.4 3.4 GO:1990357 terminal web(GO:1990357)
0.3 5.1 GO:0030478 actin cap(GO:0030478)
0.3 1.0 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 2.0 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 3.0 GO:0071953 elastic fiber(GO:0071953)
0.3 2.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.3 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 3.5 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 2.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.8 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 13.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 12.0 GO:0005581 collagen trimer(GO:0005581)
0.1 9.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.3 GO:0005605 basal lamina(GO:0005605)
0.1 1.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 2.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 6.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 9.5 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 1.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 1.2 GO:1990777 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)
0.0 0.5 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0008091 spectrin(GO:0008091)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 2.4 GO:0005902 microvillus(GO:0005902)
0.0 0.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 3.8 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 7.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 4.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 29.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0043296 apical junction complex(GO:0043296)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 3.0 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.0 10.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.8 3.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.7 2.2 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 2.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.5 1.6 GO:1902271 D3 vitamins binding(GO:1902271)
0.5 1.4 GO:0005174 CD40 receptor binding(GO:0005174)
0.5 3.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 1.3 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.4 1.3 GO:1904854 proteasome core complex binding(GO:1904854)
0.4 2.2 GO:0015254 glycerol channel activity(GO:0015254)
0.4 8.7 GO:0005537 mannose binding(GO:0005537)
0.4 2.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.4 3.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.3 1.3 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.3 2.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.3 1.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 7.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 2.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 7.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 1.7 GO:0035473 lipase binding(GO:0035473)
0.2 7.0 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 0.5 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.2 3.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2 0.8 GO:0031013 troponin I binding(GO:0031013)
0.2 1.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 2.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 4.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.5 GO:0045294 alpha-catenin binding(GO:0045294) gamma-catenin binding(GO:0045295)
0.1 7.2 GO:0042056 chemoattractant activity(GO:0042056)
0.1 1.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.8 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 2.3 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.5 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.6 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 4.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0050692 DBD domain binding(GO:0050692)
0.1 4.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 14.8 GO:0008201 heparin binding(GO:0008201)
0.1 2.2 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 1.0 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.8 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 1.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 5.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.5 GO:0042731 PH domain binding(GO:0042731)
0.0 1.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.8 GO:0005507 copper ion binding(GO:0005507)
0.0 2.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 8.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 1.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 3.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.8 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 3.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 2.5 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 11.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 17.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 18.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 12.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 7.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 6.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 1.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 5.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 13.7 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 6.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.1 PID ATM PATHWAY ATM pathway
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.4 8.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 6.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 20.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 9.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 7.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 5.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 3.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 6.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 8.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 1.2 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 13.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 5.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 4.0 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 0.8 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 2.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 2.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 2.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 3.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly