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Illumina Body Map 2

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Results for FOXC1

Z-value: 0.89

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Transcription factors associated with FOXC1

Gene Symbol Gene ID Gene Info
FOXC1
ENSG00000054598.5 forkhead box C1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXC1hg19_v2_chr6_+_1610681_16106810.281.2e-01Click!

Activity profile of FOXC1 motif

Sorted Z-values of FOXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27219849 3.21 ENST00000396344.4
HOXA10
homeobox A10
chr7_+_80231466 3.08 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chrX_+_99839799 2.63 ENST00000373031.4
TNMD
tenomodulin
chr8_-_108510224 2.44 ENST00000517746.1
ENST00000297450.3
ANGPT1
angiopoietin 1
chr5_-_39424961 1.69 ENST00000503513.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr8_-_93107443 1.62 ENST00000360348.2
ENST00000520428.1
ENST00000518992.1
ENST00000520556.1
ENST00000518317.1
ENST00000521319.1
ENST00000521375.1
ENST00000518449.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_79998864 1.52 ENST00000435819.1
CD36
CD36 molecule (thrombospondin receptor)
chr2_-_72374948 1.46 ENST00000546307.1
ENST00000474509.1
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr12_+_54348618 1.45 ENST00000243103.3
HOXC12
homeobox C12
chr12_+_54378923 1.44 ENST00000303460.4
HOXC10
homeobox C10
chr10_-_4285835 1.40 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr8_-_23261589 1.40 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2
lysyl oxidase-like 2
chr17_-_46688334 1.39 ENST00000239165.7
HOXB7
homeobox B7
chr2_-_208030295 1.26 ENST00000458272.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_-_32490859 1.23 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr8_+_75736761 1.21 ENST00000260113.2
PI15
peptidase inhibitor 15
chr4_+_68424434 1.21 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr20_+_9049303 1.19 ENST00000407043.2
ENST00000441846.1
PLCB4
phospholipase C, beta 4
chr7_-_27219632 1.17 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr8_-_93107638 1.13 ENST00000518823.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_40841276 1.11 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr12_-_29936731 1.09 ENST00000552618.1
ENST00000539277.1
ENST00000551659.1
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr3_-_195310802 1.09 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr8_+_104384616 1.08 ENST00000520337.1
CTHRC1
collagen triple helix repeat containing 1
chr12_-_76462713 1.07 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr12_+_54892550 1.06 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr5_+_40841410 1.06 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr10_-_4285923 1.05 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr1_+_150122034 1.02 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr18_+_19749386 1.02 ENST00000269216.3
GATA6
GATA binding protein 6
chr10_+_114710425 1.01 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_72375167 1.00 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr8_-_93107827 0.97 ENST00000520724.1
ENST00000518844.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr14_-_89960395 0.97 ENST00000555034.1
ENST00000553904.1
FOXN3
forkhead box N3
chr12_-_53994805 0.95 ENST00000328463.7
ATF7
activating transcription factor 7
chr3_-_168865522 0.95 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus
chr3_+_189349162 0.95 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr11_-_65359947 0.92 ENST00000597463.1
AP001362.1
Uncharacterized protein
chr9_-_89562104 0.90 ENST00000298743.7
GAS1
growth arrest-specific 1
chr3_-_129279894 0.89 ENST00000506979.1
PLXND1
plexin D1
chr15_-_50411412 0.88 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr1_+_32739733 0.87 ENST00000333070.4
LCK
lymphocyte-specific protein tyrosine kinase
chr5_+_39520499 0.87 ENST00000604954.1
CTD-2078B5.2
CTD-2078B5.2
chr10_+_114709999 0.86 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_19290483 0.86 ENST00000395592.2
ENST00000299610.4
MFAP4
microfibrillar-associated protein 4
chr14_-_81916501 0.84 ENST00000555001.1
RP11-299L17.3
RP11-299L17.3
chr8_-_93107696 0.84 ENST00000436581.2
ENST00000520583.1
ENST00000519061.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_54378849 0.84 ENST00000515593.1
HOXC10
homeobox C10
chr10_+_114710211 0.83 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr10_+_71561649 0.82 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
COL13A1
collagen, type XIII, alpha 1
chr20_+_36946029 0.81 ENST00000417318.1
BPI
bactericidal/permeability-increasing protein
chr13_-_36050819 0.80 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr8_-_116673894 0.78 ENST00000395713.2
TRPS1
trichorhinophalangeal syndrome I
chr12_-_92539614 0.77 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr15_+_76016293 0.76 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr14_-_54418598 0.76 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr3_+_46449049 0.76 ENST00000357392.4
ENST00000400880.3
ENST00000433848.1
CCRL2
chemokine (C-C motif) receptor-like 2
chr4_+_15376165 0.74 ENST00000382383.3
ENST00000429690.1
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr4_+_166794383 0.74 ENST00000061240.2
ENST00000507499.1
TLL1
tolloid-like 1
chr2_-_208030647 0.73 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr12_-_68797580 0.73 ENST00000539404.1
RP11-81H14.2
RP11-81H14.2
chr5_-_39425290 0.72 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_+_32739714 0.72 ENST00000461712.2
ENST00000373562.3
ENST00000477031.2
ENST00000373557.2
LCK
lymphocyte-specific protein tyrosine kinase
chr5_-_39425222 0.72 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_+_41363854 0.71 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr3_+_69812877 0.71 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr12_+_59989918 0.69 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_+_131438496 0.69 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr3_+_46448648 0.68 ENST00000399036.3
CCRL2
chemokine (C-C motif) receptor-like 2
chr16_-_88772670 0.67 ENST00000562544.1
RNF166
ring finger protein 166
chr3_-_73483055 0.67 ENST00000479530.1
PDZRN3
PDZ domain containing ring finger 3
chr8_+_70404996 0.66 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr7_+_139528952 0.66 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr12_-_106480587 0.65 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr12_+_131438443 0.65 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr8_-_93107855 0.64 ENST00000517919.1
ENST00000519847.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr8_+_52730143 0.64 ENST00000415643.1
AC090186.1
Uncharacterized protein
chr2_-_207078154 0.63 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr18_-_53070913 0.62 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr14_+_38033252 0.62 ENST00000554829.1
RP11-356O9.1
RP11-356O9.1
chr1_+_199996733 0.62 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr3_-_15382875 0.61 ENST00000408919.3
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr12_-_10251603 0.61 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr4_+_124571409 0.61 ENST00000514823.1
ENST00000511919.1
ENST00000508111.1
RP11-93L9.1
long intergenic non-protein coding RNA 1091
chr15_-_58571445 0.60 ENST00000558231.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr19_-_47734448 0.60 ENST00000439096.2
BBC3
BCL2 binding component 3
chr10_-_97200772 0.60 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr6_-_168479839 0.59 ENST00000283309.6
FRMD1
FERM domain containing 1
chr15_+_74911430 0.59 ENST00000562670.1
ENST00000564096.1
CLK3
CDC-like kinase 3
chr2_+_172309634 0.57 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr4_-_102267953 0.57 ENST00000523694.2
ENST00000507176.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr22_+_46449674 0.56 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr3_+_57875711 0.56 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr1_+_199996702 0.56 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr5_-_39425068 0.55 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr12_-_10251539 0.55 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chrX_+_135730297 0.55 ENST00000370629.2
CD40LG
CD40 ligand
chr3_-_49066811 0.55 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr15_+_67418047 0.54 ENST00000540846.2
SMAD3
SMAD family member 3
chr17_-_39465505 0.54 ENST00000391352.1
KRTAP16-1
keratin associated protein 16-1
chr7_+_139529040 0.53 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr7_+_151038850 0.53 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr13_-_99667960 0.53 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr3_-_133969673 0.53 ENST00000427044.2
RYK
receptor-like tyrosine kinase
chr15_+_96869165 0.53 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_207078086 0.52 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr15_+_58430368 0.52 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr1_-_150669500 0.52 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr16_+_2570431 0.52 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr1_-_150669604 0.51 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr1_+_22778337 0.51 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr12_+_93096619 0.51 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr22_-_50970566 0.50 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr2_+_66918558 0.50 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr8_-_16424871 0.50 ENST00000518026.1
MSR1
macrophage scavenger receptor 1
chr2_+_12858355 0.50 ENST00000405331.3
TRIB2
tribbles pseudokinase 2
chr12_+_122516626 0.49 ENST00000319080.7
MLXIP
MLX interacting protein
chr12_-_99038732 0.49 ENST00000393042.3
ENST00000420861.1
ENST00000299157.4
ENST00000342502.2
IKBIP
IKBKB interacting protein
chr10_+_112631547 0.49 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr4_+_147096837 0.49 ENST00000296581.5
ENST00000502781.1
LSM6
LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_+_79953310 0.48 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr11_-_66112555 0.48 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr10_+_112631699 0.48 ENST00000444997.1
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr3_+_38032216 0.48 ENST00000416303.1
VILL
villin-like
chr16_+_22517166 0.47 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr22_-_50970919 0.47 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr10_+_71561630 0.47 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
COL13A1
collagen, type XIII, alpha 1
chr12_-_49453557 0.47 ENST00000547610.1
KMT2D
lysine (K)-specific methyltransferase 2D
chr10_+_52751010 0.47 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr2_+_28974668 0.47 ENST00000296122.6
ENST00000395366.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr13_-_36429763 0.47 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr20_-_62587735 0.47 ENST00000354216.6
ENST00000369892.3
ENST00000358711.3
UCKL1
uridine-cytidine kinase 1-like 1
chr3_+_57875738 0.46 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chr1_-_228135599 0.46 ENST00000272164.5
WNT9A
wingless-type MMTV integration site family, member 9A
chr16_-_21875424 0.46 ENST00000541674.1
NPIPB4
nuclear pore complex interacting protein family, member B4
chr6_-_42016385 0.45 ENST00000502771.1
ENST00000508143.1
ENST00000514588.1
ENST00000510503.1
ENST00000415497.2
ENST00000372988.4
CCND3
cyclin D3
chr16_-_4817129 0.45 ENST00000545009.1
ENST00000219478.6
ZNF500
zinc finger protein 500
chr1_-_160492994 0.44 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr5_-_58571935 0.44 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_-_50970506 0.43 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr3_-_57326704 0.43 ENST00000487349.1
ENST00000389601.3
ASB14
ankyrin repeat and SOCS box containing 14
chr16_+_30064411 0.43 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr1_-_19811132 0.42 ENST00000433834.1
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr14_+_69726864 0.42 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr9_-_20382446 0.42 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_-_42418999 0.42 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr1_-_243349684 0.41 ENST00000522895.1
CEP170
centrosomal protein 170kDa
chr2_-_190044480 0.41 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr14_-_61191049 0.41 ENST00000556952.3
SIX4
SIX homeobox 4
chr16_+_30064444 0.41 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_134092561 0.41 ENST00000510560.1
ENST00000504234.1
ENST00000515172.1
AMOTL2
angiomotin like 2
chrY_+_59100480 0.41 ENSTR0000302805.2
SPRY3
sprouty homolog 3 (Drosophila)
chr7_+_139529085 0.41 ENST00000539806.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr13_+_27825446 0.40 ENST00000311549.6
RPL21
ribosomal protein L21
chr6_+_108882069 0.39 ENST00000406360.1
FOXO3
forkhead box O3
chr12_+_59989791 0.39 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr12_-_31479107 0.39 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr13_+_27825706 0.39 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21
ribosomal protein L21
chr8_-_93107660 0.39 ENST00000518954.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_-_62582475 0.38 ENST00000369908.5
UCKL1
uridine-cytidine kinase 1-like 1
chr12_-_31479045 0.38 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr11_+_8040739 0.38 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr1_-_151431647 0.38 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr2_-_152146385 0.38 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr8_-_93107726 0.37 ENST00000520974.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_207024306 0.37 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr1_+_223101757 0.37 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chrX_-_19689106 0.37 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr15_+_58430567 0.37 ENST00000536493.1
AQP9
aquaporin 9
chr3_-_127455200 0.37 ENST00000398101.3
MGLL
monoglyceride lipase
chr3_-_71632894 0.37 ENST00000493089.1
FOXP1
forkhead box P1
chr10_+_54074033 0.36 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr7_+_120590803 0.36 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr19_-_40919271 0.36 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr14_-_92572894 0.36 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ATXN3
ataxin 3
chr4_-_102268708 0.36 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr7_+_28452130 0.36 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr1_-_178840157 0.36 ENST00000367629.1
ENST00000234816.2
ANGPTL1
angiopoietin-like 1
chr4_-_185395191 0.35 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr22_-_38699003 0.35 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr5_+_112312399 0.34 ENST00000515408.1
ENST00000513585.1
DCP2
decapping mRNA 2
chr2_+_58655461 0.34 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr2_+_28974531 0.34 ENST00000420282.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr6_-_32083106 0.33 ENST00000442721.1
TNXB
tenascin XB
chr5_+_135468516 0.33 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5
SMAD family member 5
chr14_+_69726968 0.33 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr10_+_114710516 0.33 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr3_-_113897545 0.33 ENST00000467632.1
DRD3
dopamine receptor D3
chr15_+_63889577 0.33 ENST00000534939.1
ENST00000539570.3
FBXL22
F-box and leucine-rich repeat protein 22
chrX_+_9431324 0.32 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr9_+_71944241 0.32 ENST00000257515.8
FAM189A2
family with sequence similarity 189, member A2
chr6_-_79787902 0.32 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr17_-_37934466 0.32 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr11_+_10476851 0.32 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr15_-_72563585 0.32 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr10_+_71562180 0.31 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
COL13A1
collagen, type XIII, alpha 1
chr2_+_28974489 0.31 ENST00000455580.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr16_+_67552303 0.31 ENST00000562116.1
FAM65A
family with sequence similarity 65, member A
chr12_-_116714564 0.30 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr6_+_53794780 0.30 ENST00000505762.1
ENST00000511369.1
ENST00000431554.2
MLIP
RP11-411K7.1
muscular LMNA-interacting protein
RP11-411K7.1

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.6 3.7 GO:0035026 leading edge cell differentiation(GO:0035026)
0.5 3.4 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.4 1.2 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.4 4.6 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.4 3.0 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 1.4 GO:0018277 protein deamination(GO:0018277)
0.3 1.0 GO:0007493 endodermal cell fate determination(GO:0007493)
0.3 1.0 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.3 2.4 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.3 1.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.3 1.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 0.4 GO:0090381 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.2 0.5 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.9 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 2.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.4 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.1 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 1.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.2 GO:0070269 pyroptosis(GO:0070269)
0.1 0.8 GO:0044211 CTP salvage(GO:0044211)
0.1 3.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.8 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.5 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0050883 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.6 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0001555 oocyte growth(GO:0001555)
0.1 0.5 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 1.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 1.0 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.1 0.5 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.8 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 1.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 4.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.9 GO:0051451 myoblast migration(GO:0051451)
0.1 1.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.0 0.3 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.8 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:1902510 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) regulation of apoptotic DNA fragmentation(GO:1902510)
0.0 0.3 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.5 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.5 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.0 0.8 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.8 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.8 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.5 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 1.8 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.9 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.9 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.4 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.2 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.0 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.8 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0072189 ureter development(GO:0072189)
0.0 0.3 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 1.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.4 GO:0007272 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.4 3.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 1.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.3 3.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.2 2.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 4.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.4 GO:0042587 glycogen granule(GO:0042587)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.6 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.9 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 2.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 5.9 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0072487 MSL complex(GO:0072487)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 2.1 GO:0005902 microvillus(GO:0005902)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.4 1.6 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.4 2.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.4 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.3 0.8 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.2 0.9 GO:0015254 glycerol channel activity(GO:0015254)
0.2 1.6 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 3.7 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.0 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.5 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.8 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.6 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.3 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.0 1.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 3.5 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.9 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 4.2 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 2.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 5.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.6 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 4.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 6.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.9 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.4 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis