ISMARA results: FOXJ2

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Illumina Body Map 2

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Results for FOXJ2

Z-value: 0.63

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Transcription factors associated with FOXJ2

Gene Symbol	Gene ID	Gene Info
FOXJ2 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000065970.4	forkhead box J2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXJ2	hg19_v2_chr12_+_8185288_8185339	0.66	4.2e-05	Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_134029937 Show fit	1.92	ENST00000518108.1	TG Ensembl NCBI GeneCards UniProt NextProt Show fit	thyroglobulin
chr19_+_11658655 Show fit	1.87	ENST00000588935.1	CNN1 Ensembl NCBI GeneCards UniProt NextProt Show fit	calponin 1, basic, smooth muscle
chr7_+_73242069 Show fit	1.58	ENST00000435050.1	CLDN4 Ensembl NCBI GeneCards UniProt NextProt Show fit	claudin 4
chr12_-_91574142 Show fit	1.57	ENST00000547937.1	DCN Ensembl NCBI GeneCards UniProt NextProt Show fit	decorin
chr15_-_56757329 Show fit	1.55	ENST00000260453.3	MNS1 Ensembl NCBI GeneCards UniProt NextProt Show fit	meiosis-specific nuclear structural 1
chr19_-_55677920 Show fit	1.38	ENST00000524407.2 ENST00000526003.1 ENST00000534170.1	DNAAF3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dynein, axonemal, assembly factor 3
chr8_+_104383728 Show fit	1.37	ENST00000330295.5	CTHRC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen triple helix repeat containing 1
chr8_+_104383759 Show fit	1.33	ENST00000415886.2	CTHRC1 Ensembl NCBI GeneCards UniProt NextProt Show fit	collagen triple helix repeat containing 1
chr4_+_68424434 Show fit	1.30	ENST00000265404.2 ENST00000396225.1	STAP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	signal transducing adaptor family member 1
chr13_-_38172863 Show fit	1.28	ENST00000541481.1 ENST00000379743.4 ENST00000379742.4 ENST00000379749.4 ENST00000541179.1 ENST00000379747.4	POSTN Ensembl NCBI GeneCards UniProt NextProt Show fit	periostin, osteoblast specific factor

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	GO:0061436	establishment of skin barrier(GO:0061436)
0.3	2.7	GO:0043932	ossification involved in bone remodeling(GO:0043932)
0.2	2.4	GO:0003350	pulmonary myocardium development(GO:0003350)
0.0	2.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	1.9	GO:0015705	iodide transport(GO:0015705)
0.1	1.9	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	1.7	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.1	1.6	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.3	1.4	GO:0051622	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4	1.3	GO:1903980	negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)

Showing 1 to 10 of 59 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.4	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.0	2.2	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	1.8	GO:0005581	collagen trimer(GO:0005581)
0.1	1.7	GO:0072687	meiotic spindle(GO:0072687)
0.1	1.6	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	1.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	1.5	GO:0036126	sperm flagellum(GO:0036126)
0.0	1.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.2	GO:0001533	cornified envelope(GO:0001533)
0.1	0.9	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Showing 1 to 10 of 37 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	2.9	GO:0005179	hormone activity(GO:0005179)
0.1	2.7	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	2.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	2.4	GO:0005518	collagen binding(GO:0005518)
0.3	1.4	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.2	1.3	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	1.3	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	1.0	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	1.0	GO:0003785	actin monomer binding(GO:0003785)

Showing 1 to 10 of 39 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	2.6	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.3	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	1.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	1.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Showing 1 to 8 of 8 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Total log-likelihood	Term	Description
1.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
1.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
1.1	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.7	REACTOME KINESINS	Genes involved in Kinesins
0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.5	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway

Showing 1 to 10 of 11 entries

Results for FOXJ2

Z-value: 0.63

Motif logo

Transcription factors associated with FOXJ2

Activity-expression correlation:

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: