ISMARA results: FOXN1

Project

Illumina Body Map 2

Navigation

Downloads

Results for FOXN1

Z-value: 1.01

Motif logo

Transcription factors associated with FOXN1

Gene Symbol	Gene ID	Gene Info
FOXN1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000109101.3	forkhead box N1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXN1	hg19_v2_chr17_+_26833250_26833278	-0.08	6.5e-01	Click!

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr17_-_47308128 Show fit	2.08	ENST00000413580.1 ENST00000511066.1	PHOSPHO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase, orphan 1
chr5_+_110559603 Show fit	2.07	ENST00000512453.1	CAMK4 Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase IV
chr17_-_42462688 Show fit	1.95	ENST00000377068.3	ITGA2B Ensembl NCBI GeneCards UniProt NextProt Show fit	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr3_-_38691119 Show fit	1.65	ENST00000333535.4 ENST00000413689.1 ENST00000443581.1 ENST00000425664.1 ENST00000451551.2	SCN5A Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, voltage-gated, type V, alpha subunit
chr5_+_110559784 Show fit	1.63	ENST00000282356.4	CAMK4 Ensembl NCBI GeneCards UniProt NextProt Show fit	calcium/calmodulin-dependent protein kinase IV
chr17_-_47308100 Show fit	1.61	ENST00000503902.1 ENST00000512250.1	PHOSPHO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphatase, orphan 1
chr5_-_79866054 Show fit	1.61	ENST00000508916.1	ANKRD34B Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat domain 34B
chr1_+_181057638 Show fit	1.56	ENST00000367577.4	IER5 Ensembl NCBI GeneCards UniProt NextProt Show fit	immediate early response 5
chr14_-_51297360 Show fit	1.55	ENST00000496749.1	NIN Ensembl NCBI GeneCards UniProt NextProt Show fit	ninein (GSK3B interacting protein)
chr2_+_46769798 Show fit	1.53	ENST00000238738.4	RHOQ Ensembl NCBI GeneCards UniProt NextProt Show fit	ras homolog family member Q

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	3.7	GO:0002372	myeloid dendritic cell cytokine production(GO:0002372)
0.2	3.7	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	3.6	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.2	3.5	GO:0090222	centrosome-templated microtubule nucleation(GO:0090222)
0.0	3.5	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	3.3	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	2.6	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	2.4	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1	2.3	GO:0044351	macropinocytosis(GO:0044351)
0.1	2.0	GO:0046475	glycerophospholipid catabolic process(GO:0046475)

Showing 1 to 10 of 138 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.2	3.5	GO:0036449	microtubule minus-end(GO:0036449)
0.1	3.1	GO:0097228	sperm principal piece(GO:0097228)
0.0	2.8	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	2.8	GO:0001650	fibrillar center(GO:0001650)
0.2	2.5	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	1.9	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	1.7	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	1.5	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	1.4	GO:0055038	recycling endosome membrane(GO:0055038)

Showing 1 to 10 of 58 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.0	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	3.8	GO:0043022	ribosome binding(GO:0043022)
0.3	3.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	3.5	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.3	3.3	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	2.8	GO:0050699	WW domain binding(GO:0050699)
0.0	2.7	GO:0017124	SH3 domain binding(GO:0017124)
0.6	2.4	GO:0032427	GBD domain binding(GO:0032427)
0.1	2.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	2.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Showing 1 to 10 of 91 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.6	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	2.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	2.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	2.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	1.9	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	1.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	1.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	1.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.0	PID RHOA PATHWAY	RhoA signaling pathway

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	3.7	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.1	3.6	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	2.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	2.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.1	1.9	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.9	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	1.8	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters

Showing 1 to 10 of 41 entries

Results for FOXN1

Z-value: 1.01

Motif logo

Transcription factors associated with FOXN1

Activity-expression correlation:

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: