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Illumina Body Map 2

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Results for GATA6

Z-value: 1.04

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Transcription factors associated with GATA6

Gene Symbol Gene ID Gene Info
GATA6
ENSG00000141448.4 GATA binding protein 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA6hg19_v2_chr18_+_19750894_197509800.096.2e-01Click!

Activity profile of GATA6 motif

Sorted Z-values of GATA6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_100239132 4.41 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr11_-_116708302 4.07 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1
apolipoprotein A-I
chr2_+_102927962 3.67 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr12_-_54689532 3.50 ENST00000540264.2
ENST00000312156.4
NFE2
nuclear factor, erythroid 2
chr12_-_10151773 3.31 ENST00000298527.6
ENST00000348658.4
CLEC1B
C-type lectin domain family 1, member B
chr1_-_27240455 3.03 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr17_+_4675175 2.98 ENST00000270560.3
TM4SF5
transmembrane 4 L six family member 5
chr13_-_46716969 2.76 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr9_-_117692697 2.71 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr2_+_102928009 2.71 ENST00000404917.2
ENST00000447231.1
IL1RL1
interleukin 1 receptor-like 1
chr10_-_99531709 2.50 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr6_-_30128657 2.33 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr1_-_167487808 2.23 ENST00000392122.3
CD247
CD247 molecule
chr2_+_87565634 2.05 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr1_-_167487758 2.05 ENST00000362089.5
CD247
CD247 molecule
chr2_+_44066101 1.99 ENST00000272286.2
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr2_-_90538397 1.97 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr3_+_137717571 1.90 ENST00000343735.4
CLDN18
claudin 18
chr18_-_2982869 1.85 ENST00000584915.1
LPIN2
lipin 2
chr18_+_19749386 1.80 ENST00000269216.3
GATA6
GATA binding protein 6
chr2_-_69098566 1.77 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr10_-_129691195 1.73 ENST00000368671.3
CLRN3
clarin 3
chr6_+_50061315 1.65 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr2_-_44065946 1.58 ENST00000260645.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr15_-_38852251 1.56 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr12_-_120765565 1.45 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chr19_+_14138960 1.45 ENST00000431365.2
ENST00000585987.1
RLN3
relaxin 3
chr4_-_103266219 1.44 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr5_-_135290705 1.44 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr17_+_4835580 1.42 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr17_-_29645836 1.38 ENST00000578584.1
CTD-2370N5.3
CTD-2370N5.3
chr11_-_47374246 1.38 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3
myosin binding protein C, cardiac
chr12_-_103344615 1.37 ENST00000546844.1
PAH
phenylalanine hydroxylase
chr2_-_44065889 1.32 ENST00000543989.1
ENST00000405322.1
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr1_-_226187013 1.27 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr12_-_52995291 1.23 ENST00000293745.2
ENST00000354310.4
KRT72
keratin 72
chr19_+_36132631 1.20 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr3_+_148583043 1.17 ENST00000296046.3
CPA3
carboxypeptidase A3 (mast cell)
chr4_-_48683188 1.16 ENST00000505759.1
FRYL
FRY-like
chr7_+_155090271 1.15 ENST00000476756.1
INSIG1
insulin induced gene 1
chr6_+_31674639 1.12 ENST00000556581.1
ENST00000375832.4
ENST00000503322.1
LY6G6F
MEGT1
lymphocyte antigen 6 complex, locus G6F
HCG43720, isoform CRA_a; Lymphocyte antigen 6 complex locus protein G6f; Megakaryocyte-enhanced gene transcript 1 protein; Uncharacterized protein
chr14_-_23284675 1.06 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_-_23284703 1.06 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr2_+_138722028 1.05 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr4_-_103266355 1.02 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr20_+_43029911 1.01 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_71560023 0.98 ENST00000572450.1
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr16_+_71560154 0.96 ENST00000539698.3
CHST4
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr17_+_38673270 0.93 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr12_+_111843749 0.85 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr19_-_13213662 0.84 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr1_+_25599018 0.83 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr14_+_75988851 0.81 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75988768 0.79 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr4_+_100495864 0.78 ENST00000265517.5
ENST00000422897.2
MTTP
microsomal triglyceride transfer protein
chr6_+_130339710 0.78 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr9_-_114937543 0.76 ENST00000374264.2
ENST00000374263.3
SUSD1
sushi domain containing 1
chr17_-_4806369 0.74 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr19_-_39303576 0.72 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr9_-_114937676 0.71 ENST00000374270.3
SUSD1
sushi domain containing 1
chr17_+_75283973 0.71 ENST00000431235.2
ENST00000449803.2
SEPT9
septin 9
chr11_+_75428857 0.70 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr19_+_10397648 0.68 ENST00000340992.4
ENST00000393717.2
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr14_-_38036271 0.68 ENST00000556024.1
RP11-356O9.2
RP11-356O9.2
chr12_-_52995179 0.68 ENST00000549979.1
KRT72
keratin 72
chr11_+_10326918 0.68 ENST00000528544.1
ADM
adrenomedullin
chr14_-_23285011 0.68 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_-_114937465 0.67 ENST00000355396.3
SUSD1
sushi domain containing 1
chr14_-_23285069 0.67 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_+_10397621 0.67 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr3_+_137490748 0.65 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr17_+_74381343 0.64 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr9_+_125796806 0.64 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr11_-_116371347 0.63 ENST00000452629.1
AP001891.1
AP001891.1
chr5_+_1201703 0.63 ENST00000304460.10
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr6_+_138699042 0.61 ENST00000573100.1
RP3-422G23.4
Uncharacterized protein
chr18_-_28742813 0.61 ENST00000257197.3
ENST00000257198.5
DSC1
desmocollin 1
chr5_+_159848807 0.59 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr2_-_40739501 0.57 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr8_-_20040638 0.56 ENST00000519026.1
ENST00000276373.5
ENST00000440926.1
ENST00000437980.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr19_-_13213954 0.56 ENST00000590974.1
LYL1
lymphoblastic leukemia derived sequence 1
chr19_-_11494975 0.56 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr2_-_202298268 0.55 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr11_+_10326612 0.52 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr14_+_105952648 0.49 ENST00000330233.7
CRIP1
cysteine-rich protein 1 (intestinal)
chr22_-_29784519 0.49 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1
adaptor-related protein complex 1, beta 1 subunit
chr8_-_20040601 0.48 ENST00000265808.7
ENST00000522513.1
SLC18A1
solute carrier family 18 (vesicular monoamine transporter), member 1
chr20_+_51588873 0.48 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chrX_+_37865804 0.46 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr20_+_31669333 0.45 ENST00000375483.3
BPIFB4
BPI fold containing family B, member 4
chrX_+_107288280 0.45 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr1_+_25598989 0.44 ENST00000454452.2
RHD
Rh blood group, D antigen
chr1_+_206317450 0.43 ENST00000358184.2
ENST00000361052.3
ENST00000360218.2
CTSE
cathepsin E
chr11_-_66206260 0.40 ENST00000329819.4
ENST00000310999.7
ENST00000430466.2
MRPL11
mitochondrial ribosomal protein L11
chr14_-_38028689 0.40 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr1_+_12524965 0.39 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr2_+_169757750 0.37 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2
glucose-6-phosphatase, catalytic, 2
chr6_-_86099898 0.35 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr14_+_22966642 0.34 ENST00000390496.1
TRAJ41
T cell receptor alpha joining 41
chr17_-_62084241 0.33 ENST00000449662.2
ICAM2
intercellular adhesion molecule 2
chr4_-_186696636 0.32 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_173792893 0.31 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_-_120354079 0.30 ENST00000354219.1
ENST00000369401.4
ENST00000256585.5
REG4
regenerating islet-derived family, member 4
chr1_+_206317591 0.26 ENST00000432969.2
CTSE
cathepsin E
chr17_+_56833184 0.25 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr15_+_81391740 0.24 ENST00000561216.1
C15orf26
chromosome 15 open reading frame 26
chr20_-_30795511 0.22 ENST00000246229.4
PLAGL2
pleiomorphic adenoma gene-like 2
chr2_-_214014959 0.21 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr8_+_21823726 0.18 ENST00000433566.4
XPO7
exportin 7
chr11_+_118958689 0.18 ENST00000535253.1
ENST00000392841.1
HMBS
hydroxymethylbilane synthase
chr12_-_21928515 0.13 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr2_-_214015111 0.11 ENST00000433134.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_-_135290651 0.11 ENST00000522943.1
ENST00000514447.2
LECT2
leukocyte cell-derived chemotaxin 2
chr2_+_3642545 0.11 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr1_+_50574585 0.10 ENST00000371824.1
ENST00000371823.4
ELAVL4
ELAV like neuron-specific RNA binding protein 4
chr5_-_141703713 0.10 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr15_+_49715293 0.10 ENST00000267843.4
ENST00000560270.1
FGF7
fibroblast growth factor 7
chr14_-_21945057 0.08 ENST00000397762.1
RAB2B
RAB2B, member RAS oncogene family
chr8_-_93107660 0.07 ENST00000518954.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr22_-_20231207 0.06 ENST00000425986.1
RTN4R
reticulon 4 receptor
chrX_+_107288197 0.06 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr8_-_116681686 0.04 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr7_+_150690857 0.04 ENST00000484524.1
ENST00000467517.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr3_-_122694215 0.04 ENST00000449546.1
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr7_+_142749417 0.04 ENST00000418316.1
OR6V1
olfactory receptor, family 6, subfamily V, member 1
chr5_+_135496675 0.03 ENST00000507637.1
SMAD5
SMAD family member 5
chr9_+_118950325 0.02 ENST00000534838.1
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr5_+_131409476 0.00 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
1.0 4.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.9 6.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.7 4.4 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.6 1.2 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.6 1.8 GO:0007493 endodermal cell fate determination(GO:0007493)
0.4 1.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 2.5 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3 3.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.3 1.5 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 1.6 GO:0032252 secretory granule localization(GO:0032252)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 2.5 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.4 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.2 1.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 0.6 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 0.6 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 1.0 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.2 1.0 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.1 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 1.9 GO:0006477 protein sulfation(GO:0006477)
0.1 1.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 2.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 2.8 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.0 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 4.3 GO:0070207 protein homotrimerization(GO:0070207)
0.1 3.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 1.0 GO:0034378 chylomicron assembly(GO:0034378)
0.1 1.4 GO:0001955 blood vessel maturation(GO:0001955)
0.1 3.3 GO:0030220 platelet formation(GO:0030220)
0.1 2.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 1.4 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 1.6 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 1.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 1.2 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 1.2 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.7 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 3.0 GO:0032024 positive regulation of insulin secretion(GO:0032024)
0.0 0.7 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.8 GO:0015695 organic cation transport(GO:0015695)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 2.5 GO:0070268 cornification(GO:0070268)
0.0 0.7 GO:0007274 synaptic transmission, cholinergic(GO:0007271) neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.4 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.3 4.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 4.9 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.3 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 4.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 1.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.7 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.9 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 1.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 3.2 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 5.3 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0002113 interleukin-33 binding(GO:0002113)
1.1 4.4 GO:0004998 transferrin receptor activity(GO:0004998)
1.0 4.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.3 1.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.3 1.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.2 1.9 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.4 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.2 3.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.6 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 3.5 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.8 GO:0031433 telethonin binding(GO:0031433)
0.1 3.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.7 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 3.5 GO:0050699 WW domain binding(GO:0050699)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 4.3 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.7 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0038131 neuregulin receptor activity(GO:0038131)
0.0 0.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 3.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 9.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 4.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 4.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.7 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 4.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 5.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 2.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis