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Illumina Body Map 2
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Results for GUAAACA
Z-value: 1.06
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miRNA associated with seed GUAAACA
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_+_52495426 Show fit | 1.84 |
ENST00000262094.5
|
RAB27B, member RAS oncogene family |
|
| chr5_+_110559784 Show fit | 1.71 |
ENST00000282356.4
|
calcium/calmodulin-dependent protein kinase IV |
|
| chr7_-_27224795 Show fit | 1.45 |
ENST00000006015.3
|
homeobox A11 |
|
| chr14_-_99737565 Show fit | 1.32 |
ENST00000357195.3
|
B-cell CLL/lymphoma 11B (zinc finger protein) |
|
| chr14_-_24047965 Show fit | 1.27 |
ENST00000397118.3
ENST00000356300.4 |
junctophilin 4 |
|
| chr6_-_40555176 Show fit | 1.26 |
ENST00000338305.6
|
leucine rich repeat and fibronectin type III domain containing 2 |
|
| chr1_+_50574585 Show fit | 1.24 |
ENST00000371824.1
ENST00000371823.4 |
ELAV like neuron-specific RNA binding protein 4 |
|
| chr9_-_23821273 Show fit | 1.13 |
ENST00000380110.4
|
ELAV like neuron-specific RNA binding protein 2 |
|
| chr7_-_143059845 Show fit | 1.09 |
ENST00000443739.2
|
family with sequence similarity 131, member B |
|
| chr6_-_30654977 Show fit | 1.02 |
ENST00000399199.3
|
protein phosphatase 1, regulatory subunit 18 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUAAACA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.6 | 1.7 | GO:0002372 | myeloid dendritic cell cytokine production(GO:0002372) |
| 0.4 | 1.3 | GO:0097534 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
| 0.1 | 1.3 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.1 | 1.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.1 | 1.3 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 1.2 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 1.2 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 1.1 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.1 | 1.1 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 2.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 1.9 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 1.8 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 1.7 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 1.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.3 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 1.1 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.1 | 1.0 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.1 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 3.0 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 2.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 2.1 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.0 | 2.1 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.0 | 1.8 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 1.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 1.5 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 1.3 | GO:0016018 | cyclosporin A binding(GO:0016018) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 2.2 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.6 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 1.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 1.1 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.8 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.7 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.7 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.0 | 1.9 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.7 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 1.6 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.6 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.3 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 1.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.1 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |