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Illumina Body Map 2

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Results for GZF1

Z-value: 0.42

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.11 GDNF inducible zinc finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GZF1hg19_v2_chr20_+_23342783_23342957-0.212.4e-01Click!

Activity profile of GZF1 motif

Sorted Z-values of GZF1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27183263 1.93 ENST00000222726.3
HOXA5
homeobox A5
chr12_+_54384370 1.36 ENST00000504315.1
HOXC6
homeobox C6
chr3_-_87040233 1.19 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr3_-_87039662 1.07 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr3_+_30648066 0.75 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_-_87040259 0.73 ENST00000383698.3
VGLL3
vestigial like 3 (Drosophila)
chr3_+_30647994 0.72 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_-_79816965 0.69 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_+_22293618 0.65 ENST00000390432.2
TRAV10
T cell receptor alpha variable 10
chr1_+_26606608 0.60 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_36157715 0.49 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr14_-_52535712 0.47 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr11_+_101918153 0.47 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70
chromosome 11 open reading frame 70
chr5_+_92919043 0.46 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr5_+_170814803 0.44 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr1_+_9711781 0.42 ENST00000536656.1
ENST00000377346.4
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
chr7_-_26904317 0.39 ENST00000345317.2
SKAP2
src kinase associated phosphoprotein 2
chr1_-_201438282 0.37 ENST00000367311.3
ENST00000367309.1
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr3_-_170588163 0.36 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr14_-_92413353 0.35 ENST00000556154.1
FBLN5
fibulin 5
chr19_-_59084647 0.35 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr8_+_23430157 0.35 ENST00000399967.3
FP15737
FP15737
chr9_-_124976154 0.34 ENST00000482062.1
LHX6
LIM homeobox 6
chr4_-_147443043 0.31 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
SLC10A7
solute carrier family 10, member 7
chr1_+_32757668 0.31 ENST00000373548.3
HDAC1
histone deacetylase 1
chr9_-_124976185 0.30 ENST00000464484.2
LHX6
LIM homeobox 6
chr14_-_92413727 0.28 ENST00000267620.10
FBLN5
fibulin 5
chr19_-_59084922 0.28 ENST00000215057.2
ENST00000599369.1
MZF1
myeloid zinc finger 1
chrX_+_153238220 0.27 ENST00000425274.1
TMEM187
transmembrane protein 187
chr2_-_74776586 0.27 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr1_+_32757718 0.27 ENST00000428704.1
HDAC1
histone deacetylase 1
chr12_-_76478386 0.27 ENST00000535020.2
NAP1L1
nucleosome assembly protein 1-like 1
chr19_-_14628645 0.26 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr12_-_76478446 0.26 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
NAP1L1
nucleosome assembly protein 1-like 1
chr12_-_76478417 0.26 ENST00000552342.1
NAP1L1
nucleosome assembly protein 1-like 1
chr6_-_42418999 0.25 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr4_-_147442817 0.25 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr16_+_67876180 0.25 ENST00000303596.1
THAP11
THAP domain containing 11
chr9_-_14308004 0.24 ENST00000493697.1
NFIB
nuclear factor I/B
chr20_+_42086525 0.22 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr6_+_30525051 0.20 ENST00000376557.3
PRR3
proline rich 3
chr19_-_36545128 0.19 ENST00000538849.1
THAP8
THAP domain containing 8
chr6_+_30524663 0.18 ENST00000376560.3
PRR3
proline rich 3
chr9_+_96338860 0.17 ENST00000375376.4
PHF2
PHD finger protein 2
chr16_+_86612112 0.17 ENST00000320241.3
FOXL1
forkhead box L1
chr4_+_26344754 0.17 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_2461684 0.15 ENST00000378453.3
HES5
hes family bHLH transcription factor 5
chr16_-_30582888 0.15 ENST00000563707.1
ENST00000567855.1
ZNF688
zinc finger protein 688
chr8_+_112388852 0.13 ENST00000521904.1
ENST00000521753.1
RP11-1101K5.1
RP11-1101K5.1
chr4_-_147442982 0.13 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr3_+_51705222 0.13 ENST00000457573.1
ENST00000341333.5
ENST00000412249.1
ENST00000425781.1
ENST00000415259.1
ENST00000395057.1
ENST00000416589.1
TEX264
testis expressed 264
chr17_-_70588936 0.13 ENST00000453722.2
LINC00511
long intergenic non-protein coding RNA 511
chr15_+_78370140 0.11 ENST00000409568.2
SH2D7
SH2 domain containing 7
chr10_-_126849068 0.11 ENST00000494626.2
ENST00000337195.5
CTBP2
C-terminal binding protein 2
chr12_+_102513950 0.09 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chrX_+_102883620 0.08 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr10_+_97759848 0.07 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr9_+_96338647 0.06 ENST00000359246.4
PHF2
PHD finger protein 2
chr1_-_42384343 0.05 ENST00000372584.1
HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr7_+_102004322 0.05 ENST00000496391.1
PRKRIP1
PRKR interacting protein 1 (IL11 inducible)
chr19_-_3786253 0.05 ENST00000585778.1
MATK
megakaryocyte-associated tyrosine kinase
chr10_+_89264625 0.05 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr13_+_98086445 0.05 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr19_-_3786354 0.04 ENST00000395040.2
ENST00000310132.6
MATK
megakaryocyte-associated tyrosine kinase
chr6_+_7108210 0.04 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1
ras responsive element binding protein 1
chr16_-_70285797 0.04 ENST00000435634.1
EXOSC6
exosome component 6
chr12_-_102513843 0.04 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr22_+_50639408 0.04 ENST00000380903.2
SELO
Selenoprotein O
chr2_-_27603582 0.03 ENST00000323703.6
ENST00000436006.1
ZNF513
zinc finger protein 513
chr7_-_75115548 0.03 ENST00000453279.2
POM121C
POM121 transmembrane nucleoporin C
chr6_-_30524951 0.03 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr1_-_32801825 0.02 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr18_-_53303123 0.02 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr10_-_126849588 0.02 ENST00000411419.2
CTBP2
C-terminal binding protein 2
chr12_+_107168418 0.01 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr1_+_41174988 0.01 ENST00000372652.1
NFYC
nuclear transcription factor Y, gamma
chr10_+_14880287 0.01 ENST00000437161.2
HSPA14
heat shock 70kDa protein 14
chr12_-_120662499 0.00 ENST00000552550.1
PXN
paxillin
chr19_-_10426663 0.00 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr17_-_29648761 0.00 ENST00000247270.3
ENST00000462804.2
EVI2A
ecotropic viral integration site 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0060435 bronchiole development(GO:0060435)
0.5 1.5 GO:0002661 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 0.7 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 0.6 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 0.4 GO:0060374 positive regulation of neutrophil apoptotic process(GO:0033031) mast cell differentiation(GO:0060374)
0.1 0.3 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.6 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.2 GO:1901189 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.5 GO:0071711 basement membrane organization(GO:0071711)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 3.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1