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Illumina Body Map 2
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Results for GZF1
Z-value: 0.42
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Transcription factors associated with GZF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GZF1 | hg19_v2_chr20_+_23342783_23342957 | -0.21 | 2.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_27183263 Show fit | 1.93 |
ENST00000222726.3
|
homeobox A5 |
|
| chr12_+_54384370 Show fit | 1.36 |
ENST00000504315.1
|
homeobox C6 |
|
| chr3_-_87040233 Show fit | 1.19 |
ENST00000398399.2
|
vestigial like 3 (Drosophila) |
|
| chr3_-_87039662 Show fit | 1.07 |
ENST00000494229.1
|
vestigial like 3 (Drosophila) |
|
| chr3_+_30648066 Show fit | 0.75 |
ENST00000359013.4
|
transforming growth factor, beta receptor II (70/80kDa) |
|
| chr3_-_87040259 Show fit | 0.73 |
ENST00000383698.3
|
vestigial like 3 (Drosophila) |
|
| chr3_+_30647994 Show fit | 0.72 |
ENST00000295754.5
|
transforming growth factor, beta receptor II (70/80kDa) |
|
| chr3_-_79816965 Show fit | 0.69 |
ENST00000464233.1
|
roundabout, axon guidance receptor, homolog 1 (Drosophila) |
|
| chr14_+_22293618 Show fit | 0.65 |
ENST00000390432.2
|
T cell receptor alpha variable 10 |
|
| chr1_+_26606608 Show fit | 0.60 |
ENST00000319041.6
|
SH3 domain binding glutamic acid-rich protein like 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GZF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 1.9 | GO:0060435 | bronchiole development(GO:0060435) |
| 0.5 | 1.5 | GO:0002661 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.1 | 0.7 | GO:0021836 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.1 | 0.6 | GO:0061198 | fungiform papilla formation(GO:0061198) |
| 0.0 | 0.6 | GO:0021853 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 0.6 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.5 | GO:0071711 | basement membrane organization(GO:0071711) |
| 0.1 | 0.4 | GO:0060374 | positive regulation of neutrophil apoptotic process(GO:0033031) mast cell differentiation(GO:0060374) |
| 0.0 | 0.4 | GO:0060699 | regulation of endoribonuclease activity(GO:0060699) |
| 0.1 | 0.3 | GO:0018057 | peptidyl-lysine oxidation(GO:0018057) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.6 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.0 | 0.6 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.4 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.0 | 0.2 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.4 | 1.5 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.1 | 0.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.6 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 0.5 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.0 | 0.4 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.0 | 0.4 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.4 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.4 | GO:0008301 | DNA binding, bending(GO:0008301) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.6 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 0.4 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 0.7 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |