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Illumina Body Map 2

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Results for HAND1

Z-value: 0.89

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Transcription factors associated with HAND1

Gene Symbol Gene ID Gene Info
HAND1
ENSG00000113196.2 heart and neural crest derivatives expressed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAND1hg19_v2_chr5_-_153857819_153857824-0.173.5e-01Click!

Activity profile of HAND1 motif

Sorted Z-values of HAND1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_65409502 3.18 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_65409438 3.01 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr14_-_106642049 2.89 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr17_-_64216748 2.68 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_+_90153696 2.56 ENST00000417279.2
IGKV3D-15
immunoglobulin kappa variable 3D-15 (gene/pseudogene)
chr2_+_228678550 2.51 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr16_-_31147020 1.93 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr6_+_134210243 1.90 ENST00000367882.4
TCF21
transcription factor 21
chr7_-_116963334 1.88 ENST00000265441.3
WNT2
wingless-type MMTV integration site family member 2
chr6_-_39282329 1.63 ENST00000373231.4
KCNK17
potassium channel, subfamily K, member 17
chr7_-_116963095 1.57 ENST00000491214.1
WNT2
wingless-type MMTV integration site family member 2
chr16_-_31146961 1.51 ENST00000567531.1
PRSS8
protease, serine, 8
chr20_-_1165117 1.51 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr2_+_204732666 1.50 ENST00000295854.6
ENST00000472206.1
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr2_-_89597542 1.49 ENST00000465170.1
IGKV1-37
immunoglobulin kappa variable 1-37 (non-functional)
chr12_+_40549984 1.49 ENST00000457989.1
AC079630.2
AC079630.2
chr11_-_63330842 1.48 ENST00000255695.1
HRASLS2
HRAS-like suppressor 2
chr1_+_207262578 1.37 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr6_-_39282221 1.35 ENST00000453413.2
KCNK17
potassium channel, subfamily K, member 17
chr1_+_207262540 1.35 ENST00000452902.2
C4BPB
complement component 4 binding protein, beta
chr19_-_10213335 1.34 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr1_+_207262627 1.27 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr16_-_28608424 1.22 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_+_207262170 1.21 ENST00000367078.3
C4BPB
complement component 4 binding protein, beta
chr7_-_81399438 1.20 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr2_-_27718052 1.17 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr2_+_204732487 1.16 ENST00000302823.3
CTLA4
cytotoxic T-lymphocyte-associated protein 4
chr7_-_81399355 1.15 ENST00000457544.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399329 1.14 ENST00000453411.1
ENST00000444829.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399411 1.14 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr12_-_110271178 1.08 ENST00000261740.2
ENST00000392719.2
ENST00000346520.2
TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr17_+_45908974 1.05 ENST00000269025.4
LRRC46
leucine rich repeat containing 46
chr7_-_81399287 1.04 ENST00000354224.6
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr7_-_81399678 1.03 ENST00000412881.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_-_1165319 0.99 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr20_+_58296265 0.95 ENST00000395636.2
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr16_-_28608364 0.95 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr7_-_81399744 0.91 ENST00000421558.1
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr6_+_6588902 0.91 ENST00000230568.4
LY86
lymphocyte antigen 86
chr15_+_74509530 0.86 ENST00000321288.5
CCDC33
coiled-coil domain containing 33
chr7_+_142008340 0.86 ENST00000390387.3
TRBV3-1
T cell receptor beta variable 3-1
chr16_-_10652993 0.86 ENST00000536829.1
EMP2
epithelial membrane protein 2
chr16_-_28621353 0.84 ENST00000567512.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_27719148 0.80 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr22_+_25003626 0.80 ENST00000451366.1
ENST00000406383.2
ENST00000428855.1
GGT1
gamma-glutamyltransferase 1
chr3_+_108855558 0.78 ENST00000467240.1
ENST00000477643.1
ENST00000479039.1
ENST00000593799.1
RP11-59E19.1
RP11-59E19.1
chr15_-_76304731 0.77 ENST00000394907.3
NRG4
neuregulin 4
chr17_-_72619869 0.74 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr11_-_2323290 0.74 ENST00000381153.3
C11orf21
chromosome 11 open reading frame 21
chr17_-_56358287 0.73 ENST00000225275.3
ENST00000340482.3
MPO
myeloperoxidase
chr11_+_67171391 0.73 ENST00000312390.5
TBC1D10C
TBC1 domain family, member 10C
chr2_+_210443993 0.71 ENST00000392193.1
MAP2
microtubule-associated protein 2
chr2_+_210444142 0.69 ENST00000360351.4
ENST00000361559.4
MAP2
microtubule-associated protein 2
chr22_+_24999114 0.69 ENST00000412658.1
ENST00000445029.1
ENST00000419133.1
ENST00000400382.1
ENST00000438643.2
ENST00000452551.1
ENST00000400383.1
ENST00000412898.1
ENST00000400380.1
ENST00000455483.1
ENST00000430289.1
GGT1
gamma-glutamyltransferase 1
chr2_+_201997492 0.68 ENST00000494258.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr16_-_28621298 0.67 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr11_+_67171358 0.65 ENST00000526387.1
TBC1D10C
TBC1 domain family, member 10C
chr11_+_67171548 0.65 ENST00000542590.1
TBC1D10C
TBC1 domain family, member 10C
chr1_+_28261533 0.64 ENST00000411604.1
ENST00000373888.4
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr3_+_130300585 0.64 ENST00000511332.1
COL6A6
collagen, type VI, alpha 6
chr3_-_157251383 0.63 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr16_-_28621312 0.62 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_-_20256965 0.62 ENST00000400331.5
ENST00000332878.4
MACC1
metastasis associated in colon cancer 1
chr10_-_73479546 0.61 ENST00000441508.2
C10orf105
chromosome 10 open reading frame 105
chr12_+_27619743 0.61 ENST00000298876.4
ENST00000416383.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr19_-_36304201 0.60 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr10_-_104211294 0.59 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr4_-_40632605 0.58 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr20_+_3767547 0.58 ENST00000344256.6
ENST00000379598.5
CDC25B
cell division cycle 25B
chr11_+_2323236 0.56 ENST00000182290.4
TSPAN32
tetraspanin 32
chr11_-_2323089 0.56 ENST00000456145.2
C11orf21
chromosome 11 open reading frame 21
chr17_-_40337470 0.54 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_-_40631859 0.53 ENST00000295971.7
ENST00000319592.4
RBM47
RNA binding motif protein 47
chr6_+_6588316 0.52 ENST00000379953.2
LY86
lymphocyte antigen 86
chr4_+_41614909 0.51 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr6_-_133119668 0.51 ENST00000275227.4
ENST00000538764.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chr12_-_7261772 0.49 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr17_+_66624238 0.48 ENST00000591754.1
RP11-118B18.1
RP11-118B18.1
chr11_+_124932986 0.47 ENST00000407458.1
ENST00000298280.5
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr1_+_28261621 0.47 ENST00000549094.1
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr7_+_76139833 0.46 ENST00000257632.5
UPK3B
uroplakin 3B
chr17_+_53342311 0.46 ENST00000226067.5
HLF
hepatic leukemia factor
chr2_-_159237472 0.45 ENST00000409187.1
CCDC148
coiled-coil domain containing 148
chr11_+_124932955 0.45 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr1_+_28261492 0.44 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr20_+_816695 0.43 ENST00000246100.3
FAM110A
family with sequence similarity 110, member A
chr4_+_25162253 0.43 ENST00000512921.1
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr3_+_46919235 0.43 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr21_+_34602200 0.43 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr2_+_210444298 0.42 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr4_-_25161996 0.41 ENST00000513285.1
ENST00000382103.2
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr4_-_25162188 0.41 ENST00000302922.3
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr21_+_34602377 0.41 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr14_-_74892805 0.39 ENST00000331628.3
ENST00000554953.1
SYNDIG1L
synapse differentiation inducing 1-like
chr2_+_3642545 0.38 ENST00000382062.2
ENST00000236693.7
ENST00000349077.4
COLEC11
collectin sub-family member 11
chr1_-_54405773 0.38 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr5_+_143584814 0.36 ENST00000507359.3
KCTD16
potassium channel tetramerization domain containing 16
chr18_+_12407895 0.36 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1
slowmo homolog 1 (Drosophila)
chr22_+_25003568 0.35 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr2_-_228582709 0.35 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chrX_-_133930285 0.34 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr11_+_2323349 0.34 ENST00000381121.3
TSPAN32
tetraspanin 32
chr14_-_53331239 0.33 ENST00000553663.1
FERMT2
fermitin family member 2
chr7_+_141490017 0.33 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr14_-_93673353 0.33 ENST00000556566.1
ENST00000306954.4
C14orf142
chromosome 14 open reading frame 142
chr4_-_40632140 0.33 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr7_-_142583506 0.33 ENST00000359396.3
TRPV6
transient receptor potential cation channel, subfamily V, member 6
chr3_+_112051994 0.32 ENST00000473539.1
ENST00000315711.8
ENST00000383681.3
CD200
CD200 molecule
chr19_+_507299 0.30 ENST00000359315.5
TPGS1
tubulin polyglutamylase complex subunit 1
chr18_+_55712915 0.30 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr22_+_25003606 0.29 ENST00000432867.1
GGT1
gamma-glutamyltransferase 1
chr12_+_98909260 0.29 ENST00000556029.1
TMPO
thymopoietin
chr11_+_124933191 0.28 ENST00000532000.1
ENST00000308074.4
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr17_+_6347729 0.27 ENST00000572447.1
FAM64A
family with sequence similarity 64, member A
chr3_-_9811595 0.27 ENST00000256460.3
CAMK1
calcium/calmodulin-dependent protein kinase I
chr1_+_172745006 0.27 ENST00000432694.2
RP1-15D23.2
RP1-15D23.2
chr17_+_66624280 0.26 ENST00000585484.1
RP11-118B18.1
RP11-118B18.1
chr12_-_25801478 0.26 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr2_-_197791441 0.25 ENST00000409475.1
ENST00000354764.4
ENST00000374738.3
PGAP1
post-GPI attachment to proteins 1
chr1_-_155904187 0.25 ENST00000368321.3
ENST00000368320.3
KIAA0907
KIAA0907
chr4_-_40632757 0.25 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr17_-_61781750 0.24 ENST00000582026.1
STRADA
STE20-related kinase adaptor alpha
chr22_-_39928823 0.21 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr20_+_34020827 0.20 ENST00000374375.1
GDF5OS
growth differentiation factor 5 opposite strand
chr1_+_215747118 0.20 ENST00000448333.1
KCTD3
potassium channel tetramerization domain containing 3
chr14_+_74083548 0.20 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr7_+_18329712 0.20 ENST00000433709.2
HDAC9
histone deacetylase 9
chr1_+_174846570 0.18 ENST00000392064.2
RABGAP1L
RAB GTPase activating protein 1-like
chr7_-_150754935 0.18 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr12_+_121131970 0.17 ENST00000535656.1
MLEC
malectin
chr11_-_62477313 0.16 ENST00000464544.1
ENST00000530009.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_36608280 0.15 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_149531524 0.15 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr4_+_41614720 0.15 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr11_-_62476694 0.14 ENST00000524862.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_+_99344071 0.14 ENST00000370647.4
ENST00000370646.4
HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr20_+_22034809 0.14 ENST00000449427.1
RP11-125P18.1
RP11-125P18.1
chr15_-_79576156 0.13 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr21_-_16125773 0.13 ENST00000454128.2
AF127936.3
AF127936.3
chr9_-_123555655 0.13 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2
F-box and WD repeat domain containing 2
chr16_+_56969284 0.12 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr2_+_201997595 0.11 ENST00000470178.2
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_-_53729525 0.11 ENST00000303846.3
SP7
Sp7 transcription factor
chr10_-_99393208 0.11 ENST00000307450.6
MORN4
MORN repeat containing 4
chr10_-_118032979 0.08 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr11_-_62477103 0.08 ENST00000532818.1
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_+_88894366 0.08 ENST00000593752.1
AC092384.1
AC092384.1
chr6_-_112194484 0.07 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr11_+_369804 0.07 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr12_-_68647281 0.07 ENST00000328087.4
ENST00000538666.1
IL22
interleukin 22
chr19_+_36359341 0.07 ENST00000221891.4
APLP1
amyloid beta (A4) precursor-like protein 1
chr17_+_11924129 0.07 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr1_-_223988426 0.06 ENST00000391879.2
TP53BP2
tumor protein p53 binding protein, 2
chrX_+_49832231 0.06 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr1_-_52870059 0.05 ENST00000371566.1
ORC1
origin recognition complex, subunit 1
chr10_+_72972281 0.05 ENST00000335350.6
UNC5B
unc-5 homolog B (C. elegans)
chr19_+_45165545 0.05 ENST00000592472.1
ENST00000587729.1
ENST00000585657.1
ENST00000592789.1
ENST00000591979.1
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr2_-_42588289 0.05 ENST00000468711.1
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr10_-_118032697 0.05 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr7_-_142207004 0.04 ENST00000426318.2
TRBV10-2
T cell receptor beta variable 10-2
chr2_-_208031943 0.04 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr6_+_35996859 0.03 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr9_-_115095123 0.02 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chrX_-_34675391 0.02 ENST00000275954.3
TMEM47
transmembrane protein 47
chr1_+_202091980 0.01 ENST00000367282.5
GPR37L1
G protein-coupled receptor 37 like 1
chr14_+_96722152 0.01 ENST00000216629.6
BDKRB1
bradykinin receptor B1
chr6_-_53013620 0.01 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr11_+_6128914 0.01 ENST00000316529.3
OR56B4
olfactory receptor, family 56, subfamily B, member 4
chr16_-_54304608 0.01 ENST00000561336.1
RP11-324D17.1
HCG2045435; Uncharacterized protein
chr1_+_45478568 0.01 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr1_+_155911480 0.00 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4

Network of associatons between targets according to the STRING database.

First level regulatory network of HAND1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.6 7.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 1.9 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435)
0.5 2.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.5 5.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.4 3.4 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.4 1.1 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.2 2.7 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2 2.1 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.2 0.9 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.2 1.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 4.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.4 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.8 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 1.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 2.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.7 GO:0001878 response to yeast(GO:0001878)
0.1 0.9 GO:0070836 caveola assembly(GO:0070836)
0.1 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0015798 myo-inositol transport(GO:0015798)
0.0 6.1 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 1.5 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 2.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 2.7 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.8 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.8 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.4 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.3 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 2.6 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 GO:1990909 Wnt signalosome(GO:1990909)
0.2 1.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.7 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 3.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 2.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 7.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 3.6 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 4.9 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 1.3 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.6 4.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.4 2.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.4 1.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 6.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 0.8 GO:0004905 type I interferon receptor activity(GO:0004905)
0.2 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 1.2 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 3.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 7.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 2.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.1 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.4 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 2.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 3.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.6 GO:0003823 antigen binding(GO:0003823)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 6.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 5.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 2.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling