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Illumina Body Map 2

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Results for HIVEP1

Z-value: 1.65

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Transcription factors associated with HIVEP1

Gene Symbol Gene ID Gene Info
HIVEP1
ENSG00000095951.12 HIVEP zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIVEP1hg19_v2_chr6_+_12012536_120125710.327.5e-02Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106791536 6.52 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr14_-_107049312 5.70 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr12_-_9913489 5.54 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr14_-_106322288 5.07 ENST00000390559.2
IGHM
immunoglobulin heavy constant mu
chr22_+_22930626 4.80 ENST00000390302.2
IGLV2-33
immunoglobulin lambda variable 2-33 (non-functional)
chr2_+_219745020 4.76 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr14_-_106622419 4.55 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr14_-_106518922 4.36 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr14_-_106866934 4.06 ENST00000390618.2
IGHV3-38
immunoglobulin heavy variable 3-38 (non-functional)
chr14_-_106586656 3.73 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr14_-_106725723 3.60 ENST00000390609.2
IGHV3-23
immunoglobulin heavy variable 3-23
chr14_-_106573756 3.44 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr2_+_89999259 3.27 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr3_-_58196939 3.18 ENST00000394549.2
ENST00000461914.3
DNASE1L3
deoxyribonuclease I-like 3
chrX_+_78426469 3.04 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr14_-_106845789 2.95 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr3_-_58196688 2.82 ENST00000486455.1
DNASE1L3
deoxyribonuclease I-like 3
chr2_+_162101247 2.78 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr4_+_155484103 2.67 ENST00000302068.4
FGB
fibrinogen beta chain
chr16_-_33647696 2.63 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr16_+_33020496 2.60 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr17_-_18950950 2.59 ENST00000284154.5
GRAP
GRB2-related adaptor protein
chr9_+_127054217 2.52 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr4_+_155484155 2.48 ENST00000509493.1
FGB
fibrinogen beta chain
chr6_+_31554962 2.47 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
LST1
leukocyte specific transcript 1
chr19_-_6591113 2.46 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr4_-_109087906 2.43 ENST00000515500.1
LEF1
lymphoid enhancer-binding factor 1
chr17_-_46623441 2.35 ENST00000330070.4
HOXB2
homeobox B2
chr16_+_33006369 2.34 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr6_+_31555045 2.32 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr14_-_107114267 2.32 ENST00000454421.2
IGHV3-64
immunoglobulin heavy variable 3-64
chr3_-_111852061 2.31 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr14_+_22356029 2.31 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr22_-_37640277 2.30 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr16_+_85936295 2.30 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr16_+_32063311 2.27 ENST00000426099.1
AC142381.1
AC142381.1
chr14_+_22573582 2.25 ENST00000390453.1
TRAV24
T cell receptor alpha variable 24
chr12_-_57871853 2.20 ENST00000549602.1
ENST00000430041.2
ARHGAP9
Rho GTPase activating protein 9
chr16_+_33605231 2.18 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr16_+_32077386 2.15 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr6_+_32709119 2.13 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr22_-_37640456 2.12 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_+_47444613 2.11 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr14_-_106610852 2.11 ENST00000390603.2
IGHV3-15
immunoglobulin heavy variable 3-15
chr14_+_22433675 2.11 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr3_-_156878482 2.10 ENST00000295925.4
CCNL1
cyclin L1
chr14_-_107199464 2.09 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr3_-_111852128 2.08 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr7_-_150497406 2.08 ENST00000492607.1
ENST00000326442.5
ENST00000450753.2
TMEM176B
transmembrane protein 176B
chr12_-_57871825 2.07 ENST00000548139.1
ARHGAP9
Rho GTPase activating protein 9
chr3_-_156878540 2.06 ENST00000461804.1
CCNL1
cyclin L1
chr1_+_156119466 2.06 ENST00000414683.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr14_+_22689792 2.05 ENST00000390462.1
TRAV35
T cell receptor alpha variable 35
chr19_-_42636543 2.03 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2
POU class 2 homeobox 2
chr22_+_37257015 2.03 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4
neutrophil cytosolic factor 4, 40kDa
chr14_+_75988768 1.99 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_22788560 1.99 ENST00000390468.1
TRAV41
T cell receptor alpha variable 41
chr12_+_7055631 1.99 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_-_39219705 1.97 ENST00000351578.6
FYB
FYN binding protein
chr14_+_22771851 1.95 ENST00000390466.1
TRAV39
T cell receptor alpha variable 39
chr19_-_10445399 1.94 ENST00000592945.1
ICAM3
intercellular adhesion molecule 3
chr7_+_150497569 1.92 ENST00000004103.3
TMEM176A
transmembrane protein 176A
chr1_-_202129105 1.89 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_49843539 1.88 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr4_+_86748898 1.87 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr5_+_49962495 1.86 ENST00000515175.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_104893863 1.86 ENST00000260315.3
ENST00000526056.1
ENST00000531367.1
ENST00000456094.1
ENST00000444749.2
ENST00000393141.2
ENST00000418434.1
ENST00000393139.2
CASP5
caspase 5, apoptosis-related cysteine peptidase
chr1_+_54359854 1.85 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
DIO1
deiodinase, iodothyronine, type I
chr7_-_150497621 1.81 ENST00000434545.1
TMEM176B
transmembrane protein 176B
chr7_+_150497491 1.81 ENST00000484928.1
TMEM176A
transmembrane protein 176A
chr4_+_86749045 1.79 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr14_-_23292596 1.79 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_+_24241789 1.79 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr22_+_50986462 1.78 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr6_-_32908792 1.77 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr12_-_55367361 1.76 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr9_+_139921916 1.75 ENST00000314330.2
C9orf139
chromosome 9 open reading frame 139
chr4_-_74864386 1.73 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr6_+_31554779 1.73 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr9_-_136344197 1.69 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr9_+_127054254 1.69 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr5_-_39219641 1.67 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB
FYN binding protein
chr19_-_52133588 1.65 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr1_+_37940153 1.61 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr14_-_106926724 1.61 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr2_-_169887827 1.58 ENST00000263817.6
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr11_+_18287721 1.58 ENST00000356524.4
SAA1
serum amyloid A1
chr14_+_75988851 1.57 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_103589789 1.56 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr9_-_116837249 1.56 ENST00000466610.2
AMBP
alpha-1-microglobulin/bikunin precursor
chr11_+_116700600 1.55 ENST00000227667.3
APOC3
apolipoprotein C-III
chr11_+_116700614 1.55 ENST00000375345.1
APOC3
apolipoprotein C-III
chr11_+_18287801 1.54 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr4_-_109087872 1.54 ENST00000510624.1
LEF1
lymphoid enhancer-binding factor 1
chr12_-_55367331 1.49 ENST00000526532.1
ENST00000532757.1
TESPA1
thymocyte expressed, positive selection associated 1
chr6_+_31554826 1.49 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr6_-_31324943 1.49 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr3_-_119278446 1.49 ENST00000264246.3
CD80
CD80 molecule
chr13_-_46756351 1.48 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_204436344 1.48 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr2_-_88427568 1.46 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr14_+_22675388 1.46 ENST00000390461.2
TRAV34
T cell receptor alpha variable 34
chr11_+_71846764 1.46 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3
folate receptor 3 (gamma)
chr6_-_31239846 1.45 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C
major histocompatibility complex, class I, C
chr6_+_29691056 1.43 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr7_+_142494795 1.42 ENST00000390417.1
TRBJ2-5
T cell receptor beta joining 2-5
chr8_+_24241969 1.41 ENST00000522298.1
ADAMDEC1
ADAM-like, decysin 1
chr18_-_2982869 1.41 ENST00000584915.1
LPIN2
lipin 2
chr11_+_71846748 1.40 ENST00000445078.2
FOLR3
folate receptor 3 (gamma)
chr6_-_74231303 1.37 ENST00000309268.6
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_-_75062730 1.34 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr10_-_125851961 1.34 ENST00000346248.5
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr8_+_27169138 1.34 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr16_-_20556492 1.33 ENST00000568098.1
ACSM2B
acyl-CoA synthetase medium-chain family member 2B
chr16_+_72088376 1.32 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chrX_-_30595959 1.32 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chr2_+_61108771 1.31 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr13_-_46964177 1.31 ENST00000389908.3
KIAA0226L
KIAA0226-like
chr11_+_57227981 1.31 ENST00000335099.3
RTN4RL2
reticulon 4 receptor-like 2
chr6_+_29691198 1.30 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr7_+_142495131 1.30 ENST00000390419.1
TRBJ2-7
T cell receptor beta joining 2-7
chr6_-_74231444 1.29 ENST00000331523.2
ENST00000356303.2
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr6_-_74230741 1.29 ENST00000316292.9
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_202047843 1.28 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr17_+_40440481 1.28 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr22_+_50919944 1.28 ENST00000395738.2
ADM2
adrenomedullin 2
chr5_+_40679584 1.27 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr17_-_34207295 1.27 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr22_-_37215523 1.27 ENST00000216200.5
PVALB
parvalbumin
chr17_-_53499310 1.26 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr12_-_14133053 1.25 ENST00000609686.1
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr19_+_4229495 1.25 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr9_-_131486367 1.25 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr1_-_206671061 1.25 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr3_-_119278376 1.25 ENST00000478182.1
CD80
CD80 molecule
chr11_-_57194111 1.25 ENST00000529112.1
ENST00000529896.1
SLC43A3
solute carrier family 43, member 3
chr1_+_156117149 1.24 ENST00000435124.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chrX_-_48326764 1.23 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr7_+_98971863 1.21 ENST00000443222.1
ENST00000414376.1
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr8_+_27168988 1.21 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr17_-_26876350 1.21 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chr2_-_74781061 1.20 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3
lysyl oxidase-like 3
chr6_+_32407619 1.20 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr14_+_52313833 1.19 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr6_-_30128657 1.19 ENST00000449742.2
ENST00000376704.3
TRIM10
tripartite motif containing 10
chr1_-_8000872 1.18 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr15_+_90728145 1.17 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_+_52821841 1.17 ENST00000405128.3
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr11_-_75062829 1.17 ENST00000393505.4
ARRB1
arrestin, beta 1
chr4_+_39046615 1.16 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr2_-_235405679 1.15 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr6_-_31704282 1.15 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr7_-_22259845 1.14 ENST00000420196.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr19_+_41869894 1.13 ENST00000413014.2
TMEM91
transmembrane protein 91
chr1_-_236030216 1.13 ENST00000389794.3
ENST00000389793.2
LYST
lysosomal trafficking regulator
chr11_-_64510409 1.12 ENST00000394429.1
ENST00000394428.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_+_50919995 1.10 ENST00000362068.2
ENST00000395737.1
ADM2
adrenomedullin 2
chr16_-_74734742 1.10 ENST00000308807.7
ENST00000573267.1
MLKL
mixed lineage kinase domain-like
chr1_+_156123359 1.10 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr6_+_32605195 1.09 ENST00000374949.2
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr11_-_67276100 1.08 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr11_+_842808 1.07 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4
tetraspanin 4
chr15_+_91411810 1.07 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr22_+_42834029 1.07 ENST00000428765.1
CTA-126B4.7
CTA-126B4.7
chr14_+_95982451 1.06 ENST00000554161.1
RP11-1070N10.3
Uncharacterized protein
chr12_-_57504069 1.05 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr5_-_18746250 1.05 ENST00000512978.1
CTD-2023M8.1
CTD-2023M8.1
chr12_-_48298785 1.05 ENST00000550325.1
ENST00000546653.1
ENST00000549336.1
ENST00000535672.1
ENST00000229022.3
ENST00000548664.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr6_+_31554456 1.04 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr12_-_55375622 1.03 ENST00000316577.8
TESPA1
thymocyte expressed, positive selection associated 1
chr1_+_111770232 1.03 ENST00000369744.2
CHI3L2
chitinase 3-like 2
chr13_+_28712614 1.02 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_-_46068969 1.02 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr1_+_156123318 1.02 ENST00000368285.3
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr16_+_50730910 1.01 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr1_+_111770278 1.01 ENST00000369748.4
CHI3L2
chitinase 3-like 2
chr17_-_61523535 1.01 ENST00000584031.1
ENST00000392976.1
CYB561
cytochrome b561
chr12_+_112451120 1.00 ENST00000261735.3
ENST00000455836.1
ERP29
endoplasmic reticulum protein 29
chr6_+_29910301 0.99 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr7_+_1272522 0.97 ENST00000316333.8
UNCX
UNC homeobox
chr19_-_4902877 0.97 ENST00000381781.2
ARRDC5
arrestin domain containing 5
chr1_+_24118452 0.95 ENST00000421070.1
LYPLA2
lysophospholipase II
chr11_-_57194218 0.95 ENST00000529554.1
SLC43A3
solute carrier family 43, member 3
chr12_+_57623869 0.94 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_159893507 0.94 ENST00000368096.1
TAGLN2
transgelin 2
chr12_+_5541267 0.94 ENST00000423158.3
NTF3
neurotrophin 3
chr2_+_137523086 0.93 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr15_-_50411412 0.93 ENST00000284509.6
ATP8B4
ATPase, class I, type 8B, member 4
chr15_+_80215113 0.92 ENST00000560255.1
C15orf37
chromosome 15 open reading frame 37
chr1_+_26872324 0.92 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr15_-_41408409 0.92 ENST00000361937.3
INO80
INO80 complex subunit
chr7_-_100425112 0.92 ENST00000358173.3
EPHB4
EPH receptor B4
chr17_-_27044810 0.91 ENST00000395242.2
RAB34
RAB34, member RAS oncogene family
chr3_-_124839648 0.91 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr19_+_45254529 0.90 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr6_+_31554612 0.89 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr6_-_112115103 0.88 ENST00000462598.3
FYN
FYN oncogene related to SRC, FGR, YES
chr21_+_34775698 0.88 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr17_+_43209967 0.87 ENST00000431281.1
ENST00000591859.1
ACBD4
acyl-CoA binding domain containing 4
chr12_+_112451222 0.87 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
0.8 2.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.7 3.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.7 7.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.7 1.3 GO:0019319 hexose biosynthetic process(GO:0019319)
0.6 4.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.6 1.2 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.6 4.0 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.5 4.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.5 7.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.5 1.6 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.5 1.6 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.5 4.6 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.5 37.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 1.3 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.4 1.3 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.4 4.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.4 2.7 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.4 2.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.4 1.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.4 1.9 GO:0043335 protein unfolding(GO:0043335)
0.4 0.7 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.4 5.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 1.1 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.4 2.6 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.4 1.1 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.4 1.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 1.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 1.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.3 2.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.3 6.9 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.3 1.0 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.3 4.8 GO:0048733 sebaceous gland development(GO:0048733)
0.3 1.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.3 0.9 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.3 3.9 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.3 2.0 GO:0000255 allantoin metabolic process(GO:0000255)
0.3 0.8 GO:0052314 phytoalexin metabolic process(GO:0052314)
0.3 0.8 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.3 1.6 GO:0015722 canalicular bile acid transport(GO:0015722)
0.3 1.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.3 7.3 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.3 6.1 GO:0042832 defense response to protozoan(GO:0042832)
0.2 1.0 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 0.7 GO:0090427 activation of meiosis(GO:0090427)
0.2 1.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.9 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 27.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.2 0.7 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.2 0.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.2 3.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.2 2.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 2.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 0.6 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.2 0.6 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686) activation of protein kinase C activity(GO:1990051)
0.2 1.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 1.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 0.5 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.2 0.5 GO:1902997 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.2 3.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.2 1.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.2 0.5 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.2 0.5 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 0.5 GO:0043000 Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.2 0.7 GO:0060032 notochord regression(GO:0060032)
0.2 0.5 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.3 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2 0.7 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 2.9 GO:0015884 folic acid transport(GO:0015884)
0.2 2.8 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 1.6 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.8 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 1.1 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.8 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.1 1.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 1.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 1.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 1.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 1.7 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.8 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.4 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 3.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.4 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.1 1.0 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.9 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 1.1 GO:1905247 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.6 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 2.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 3.1 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 2.6 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 10.5 GO:0070664 negative regulation of leukocyte proliferation(GO:0070664)
0.1 0.5 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 1.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 1.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155) positive regulation of memory T cell differentiation(GO:0043382) positive regulation of T-helper 17 cell differentiation(GO:2000321) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 3.4 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.6 GO:0051601 exocyst localization(GO:0051601)
0.1 0.9 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.1 0.6 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 2.0 GO:0002335 mature B cell differentiation(GO:0002335)
0.1 3.4 GO:2000772 regulation of cellular senescence(GO:2000772)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 2.0 GO:0045730 respiratory burst(GO:0045730)
0.1 0.2 GO:0072278 thyroid-stimulating hormone secretion(GO:0070460) metanephric comma-shaped body morphogenesis(GO:0072278) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.2 GO:0015816 glycine transport(GO:0015816)
0.1 0.9 GO:0048535 lymph node development(GO:0048535)
0.1 0.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 1.8 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.9 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 0.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.5 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via serine(GO:0018242)
0.1 0.6 GO:1901623 regulation of lymphocyte chemotaxis(GO:1901623)
0.1 0.7 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 3.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.9 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 0.7 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.3 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.6 GO:0016050 vesicle organization(GO:0016050)
0.1 0.2 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 1.6 GO:0042092 type 2 immune response(GO:0042092)
0.0 1.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.0 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.4 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 1.5 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 1.1 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.2 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 1.7 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 1.9 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 1.1 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 4.6 GO:0031295 T cell costimulation(GO:0031295)
0.0 1.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.6 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.7 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.7 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.7 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.2 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.4 GO:0007631 feeding behavior(GO:0007631)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.7 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 2.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.0 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 1.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.3 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 2.5 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 3.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.7 GO:0006914 autophagy(GO:0006914)
0.0 2.2 GO:0035690 cellular response to drug(GO:0035690)
0.0 1.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.3 GO:0031103 axon regeneration(GO:0031103)
0.0 1.0 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 1.1 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 1.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) endothelial cell activation(GO:0042118)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.9 GO:0042026 protein refolding(GO:0042026)
0.0 0.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0035458 positive regulation of protein import into nucleus, translocation(GO:0033160) cellular response to interferon-beta(GO:0035458)
0.0 0.2 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.6 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.6 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.7 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0060065 uterus development(GO:0060065)
0.0 1.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.1 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0001964 startle response(GO:0001964)
0.0 1.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0006907 pinocytosis(GO:0006907)
0.0 2.9 GO:0007162 negative regulation of cell adhesion(GO:0007162)
0.0 0.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.4 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 2.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.5 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 37.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.7 7.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.5 4.6 GO:0070552 BRISC complex(GO:0070552)
0.4 1.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.3 3.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 7.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.3 4.7 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 3.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 1.2 GO:0036284 tubulobulbar complex(GO:0036284)
0.3 4.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 1.1 GO:0045160 myosin I complex(GO:0045160)
0.3 1.9 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 3.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.2 0.7 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.2 2.0 GO:0032010 phagolysosome(GO:0032010)
0.2 1.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 2.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 4.3 GO:0034774 secretory granule lumen(GO:0034774)
0.2 0.6 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 3.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.2 GO:0043196 varicosity(GO:0043196)
0.1 1.3 GO:0071953 elastic fiber(GO:0071953)
0.1 0.7 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 3.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.7 GO:1990037 Lewy body core(GO:1990037)
0.1 2.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 1.7 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 5.7 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 13.2 GO:0072562 blood microparticle(GO:0072562)
0.1 6.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.1 0.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.2 GO:0070685 macropinocytic cup(GO:0070685)
0.1 1.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.0 GO:0005916 fascia adherens(GO:0005916)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 3.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0070652 HAUS complex(GO:0070652)
0.0 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 1.3 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.6 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.9 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 9.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 7.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.3 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 1.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.7 GO:0097542 ciliary tip(GO:0097542)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.8 3.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 39.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.5 1.6 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.5 4.6 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 0.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 2.6 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.4 2.7 GO:0046979 TAP2 binding(GO:0046979)
0.4 1.6 GO:0019862 IgA binding(GO:0019862)
0.4 1.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.3 5.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.3 1.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.3 0.8 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.3 4.4 GO:0045159 myosin II binding(GO:0045159)
0.3 1.3 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.3 1.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.3 1.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 1.7 GO:0042806 fucose binding(GO:0042806)
0.2 0.7 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.2 1.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 1.3 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 4.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.2 0.6 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.2 1.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 34.6 GO:0003823 antigen binding(GO:0003823)
0.2 2.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.2 6.6 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.8 GO:0004568 chitinase activity(GO:0004568)
0.2 3.0 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 4.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 1.5 GO:0004672 protein kinase activity(GO:0004672)
0.1 1.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 2.9 GO:0005542 folic acid binding(GO:0005542)
0.1 1.5 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.3 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 3.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.8 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.1 2.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 0.4 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 3.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.4 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.7 GO:0031996 thioesterase binding(GO:0031996)
0.1 1.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 1.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 4.6 GO:0042056 chemoattractant activity(GO:0042056)
0.1 4.8 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.4 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 3.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.7 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 3.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.9 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.5 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0004645 phosphorylase activity(GO:0004645)
0.1 1.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 1.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 2.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 4.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 2.7 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.9 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.9 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.7 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.5 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 4.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.6 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.2 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 1.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 2.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 1.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 4.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 4.5 GO:0019887 protein kinase regulator activity(GO:0019887)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 8.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 8.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.9 PID CD40 PATHWAY CD40/CD40L signaling
0.1 2.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 12.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.1 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 1.9 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 2.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.1 1.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 7.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 2.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 3.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 6.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 7.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 5.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 4.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 8.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 4.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.6 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.1 4.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 3.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 4.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 7.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 0.5 REACTOME KINESINS Genes involved in Kinesins
0.1 1.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.9 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 1.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 6.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 3.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 3.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.9 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 3.4 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 5.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.3 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.5 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)