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Illumina Body Map 2

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Results for HLF_TEF

Z-value: 0.94

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Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
HLF
ENSG00000108924.9 HLF transcription factor, PAR bZIP family member
TEF
ENSG00000167074.10 TEF transcription factor, PAR bZIP family member

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HLFhg19_v2_chr17_+_53345080_533451770.441.1e-02Click!
TEFhg19_v2_chr22_+_41777927_41777971-0.105.8e-01Click!

Activity profile of HLF_TEF motif

Sorted Z-values of HLF_TEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_41356347 5.17 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr3_+_186383741 5.13 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr19_-_41388657 4.85 ENST00000301146.4
ENST00000291764.3
CYP2A7
cytochrome P450, family 2, subfamily A, polypeptide 7
chr10_-_82049424 4.47 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr4_+_104346194 4.03 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr19_+_41594377 3.05 ENST00000330436.3
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr3_-_190580404 2.78 ENST00000442080.1
GMNC
geminin coiled-coil domain containing
chr1_+_169079823 2.54 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chrX_-_33229636 2.03 ENST00000357033.4
DMD
dystrophin
chr3_+_186330712 2.01 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr14_-_104408645 1.97 ENST00000557640.1
RD3L
retinal degeneration 3-like
chr15_-_83621435 1.89 ENST00000450735.2
ENST00000426485.1
ENST00000399166.2
ENST00000304231.8
HOMER2
homer homolog 2 (Drosophila)
chr1_+_7844312 1.85 ENST00000377541.1
PER3
period circadian clock 3
chr12_-_71031185 1.78 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr11_-_18270182 1.68 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr19_+_17413663 1.67 ENST00000594999.1
MRPL34
mitochondrial ribosomal protein L34
chr7_+_90032667 1.56 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr14_-_70263979 1.48 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr7_+_90032821 1.47 ENST00000427904.1
CLDN12
claudin 12
chr12_-_71031220 1.43 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr6_+_53948328 1.42 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr3_-_10547192 1.40 ENST00000360273.2
ENST00000343816.4
ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_-_46459099 1.33 ENST00000371374.1
RCAN2
regulator of calcineurin 2
chr8_-_6735451 1.30 ENST00000297439.3
DEFB1
defensin, beta 1
chr1_+_57320437 1.28 ENST00000361249.3
C8A
complement component 8, alpha polypeptide
chr3_-_48130314 1.28 ENST00000439356.1
ENST00000395734.3
ENST00000426837.2
MAP4
microtubule-associated protein 4
chr7_-_31380502 1.22 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr18_+_32621324 1.21 ENST00000300249.5
ENST00000538170.2
ENST00000588910.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr13_-_29292956 1.16 ENST00000266943.6
SLC46A3
solute carrier family 46, member 3
chr16_+_72088376 1.15 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr1_-_161207875 1.14 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr19_+_49259325 1.12 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr11_-_14993819 1.08 ENST00000396372.2
ENST00000361010.3
ENST00000359642.3
ENST00000331587.4
CALCA
calcitonin-related polypeptide alpha
chr4_+_187187098 1.08 ENST00000403665.2
ENST00000264692.4
F11
coagulation factor XI
chr6_+_53948221 1.07 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr3_+_158787041 1.04 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr3_-_48130707 1.01 ENST00000360240.6
ENST00000383737.4
MAP4
microtubule-associated protein 4
chr8_+_110656344 1.00 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein
chr2_+_103378472 0.97 ENST00000412401.2
TMEM182
transmembrane protein 182
chr5_+_172332220 0.96 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr9_+_71820057 0.94 ENST00000539225.1
TJP2
tight junction protein 2
chr1_-_161208013 0.93 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr9_+_71819927 0.93 ENST00000535702.1
TJP2
tight junction protein 2
chr21_+_40824003 0.91 ENST00000452550.1
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr8_-_102217515 0.91 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr1_+_65613513 0.89 ENST00000395334.2
AK4
adenylate kinase 4
chr1_-_161207953 0.87 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr7_+_23146271 0.87 ENST00000545771.1
KLHL7
kelch-like family member 7
chr10_-_94050820 0.86 ENST00000265997.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr5_-_140013224 0.85 ENST00000498971.2
CD14
CD14 molecule
chr19_+_49258775 0.83 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr5_-_140013241 0.82 ENST00000519715.1
CD14
CD14 molecule
chr1_-_161207986 0.80 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr7_-_15601595 0.79 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr7_-_111428957 0.79 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr7_+_23145884 0.79 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chr8_-_102216925 0.77 ENST00000517844.1
ZNF706
zinc finger protein 706
chr14_-_21489271 0.77 ENST00000553593.1
NDRG2
NDRG family member 2
chr5_-_140013275 0.76 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr4_+_187187337 0.75 ENST00000492972.2
F11
coagulation factor XI
chr1_-_156721389 0.74 ENST00000537739.1
HDGF
hepatoma-derived growth factor
chr8_-_102218292 0.73 ENST00000518336.1
ENST00000520454.1
ZNF706
zinc finger protein 706
chr17_-_61850894 0.73 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr4_-_65275162 0.71 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr2_+_179184955 0.71 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr1_-_203155868 0.69 ENST00000255409.3
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr8_-_102217796 0.68 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706
zinc finger protein 706
chr5_-_138533973 0.67 ENST00000507002.1
ENST00000505830.1
ENST00000508639.1
ENST00000265195.5
SIL1
SIL1 nucleotide exchange factor
chr12_-_75603643 0.66 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr3_+_160559931 0.65 ENST00000464260.1
ENST00000295839.9
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr12_-_75603482 0.65 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr14_+_67708344 0.64 ENST00000557237.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr8_-_27469383 0.63 ENST00000519742.1
CLU
clusterin
chr3_+_195869379 0.61 ENST00000457079.1
LINC00885
long intergenic non-protein coding RNA 885
chr2_-_31637560 0.60 ENST00000379416.3
XDH
xanthine dehydrogenase
chr9_-_95298927 0.60 ENST00000395534.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_+_157997273 0.60 ENST00000541722.1
ENST00000512619.1
GLRB
glycine receptor, beta
chr5_-_138534071 0.60 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr2_-_203103185 0.57 ENST00000409205.1
SUMO1
small ubiquitin-like modifier 1
chr1_+_196621156 0.57 ENST00000359637.2
CFH
complement factor H
chr8_-_42397037 0.57 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_12714006 0.56 ENST00000541207.1
DUSP16
dual specificity phosphatase 16
chr1_+_90308981 0.56 ENST00000527156.1
LRRC8D
leucine rich repeat containing 8 family, member D
chr8_+_68864330 0.55 ENST00000288368.4
PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr8_+_110552337 0.54 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr5_-_171404730 0.54 ENST00000518752.1
FBXW11
F-box and WD repeat domain containing 11
chr8_+_42396936 0.54 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr9_-_95298314 0.54 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr4_+_48807155 0.53 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr3_+_124303512 0.53 ENST00000454902.1
KALRN
kalirin, RhoGEF kinase
chr12_-_122884553 0.53 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr1_-_167883327 0.53 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr1_+_161087873 0.52 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1
nitrilase 1
chr12_+_52431016 0.52 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr13_+_23755099 0.52 ENST00000537476.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr1_+_229440129 0.51 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr13_-_46626820 0.50 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr13_+_23755127 0.50 ENST00000545013.1
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr16_+_70332956 0.50 ENST00000288071.6
ENST00000393657.2
ENST00000355992.3
ENST00000567706.1
DDX19B
RP11-529K1.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Uncharacterized protein
chr16_+_3508096 0.50 ENST00000577013.1
ENST00000570819.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr5_+_95997769 0.49 ENST00000338252.3
ENST00000508830.1
CAST
calpastatin
chr11_-_33795893 0.49 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3
F-box protein 3
chr7_-_44887620 0.49 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2AFV
H2A histone family, member V
chr1_-_226496772 0.49 ENST00000359525.2
ENST00000460719.1
LIN9
lin-9 homolog (C. elegans)
chr17_+_685513 0.47 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr12_-_12714025 0.47 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr8_+_110552831 0.46 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr10_-_14372870 0.46 ENST00000357447.2
FRMD4A
FERM domain containing 4A
chr8_-_27468717 0.45 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr6_-_133055815 0.45 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr6_+_24126350 0.45 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
NRSN1
neurensin 1
chr9_-_128246769 0.44 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr3_-_58200398 0.44 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr7_+_73868439 0.43 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr19_-_6459746 0.43 ENST00000301454.4
ENST00000334510.5
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr1_+_144989309 0.43 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr4_+_144258288 0.43 ENST00000514639.1
GAB1
GRB2-associated binding protein 1
chr10_+_18629628 0.42 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_-_43557791 0.42 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr3_-_122712079 0.42 ENST00000393583.2
SEMA5B
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
chr13_-_33780133 0.42 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr3_+_154797877 0.41 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr12_-_120966943 0.41 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr14_-_67826486 0.41 ENST00000555431.1
ENST00000554236.1
ENST00000555474.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr15_+_58430368 0.41 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr15_+_58430567 0.41 ENST00000536493.1
AQP9
aquaporin 9
chr1_+_25757376 0.40 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
TMEM57
transmembrane protein 57
chr1_+_154377669 0.39 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr4_-_70725856 0.39 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr14_+_93260642 0.38 ENST00000355976.2
GOLGA5
golgin A5
chr3_+_141103634 0.37 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_+_150404904 0.36 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr18_+_21032781 0.36 ENST00000339486.3
RIOK3
RIO kinase 3
chr14_+_60715928 0.36 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr8_-_27468945 0.36 ENST00000405140.3
CLU
clusterin
chr9_+_110045418 0.32 ENST00000419616.1
RAD23B
RAD23 homolog B (S. cerevisiae)
chr5_+_95998070 0.32 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr9_-_114246635 0.32 ENST00000338205.5
KIAA0368
KIAA0368
chr9_+_136399929 0.32 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr10_-_31996316 0.32 ENST00000433770.1
RP11-472N13.3
RP11-472N13.3
chr7_+_44646177 0.32 ENST00000443864.2
ENST00000447398.1
ENST00000449767.1
ENST00000419661.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr5_-_147286065 0.32 ENST00000318315.4
ENST00000515291.1
C5orf46
chromosome 5 open reading frame 46
chr14_+_93260569 0.31 ENST00000163416.2
GOLGA5
golgin A5
chr9_+_124103625 0.31 ENST00000594963.1
AL161784.1
Uncharacterized protein
chr5_+_134303591 0.31 ENST00000282611.6
CATSPER3
cation channel, sperm associated 3
chr7_+_44646162 0.31 ENST00000439616.2
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr3_+_154798162 0.30 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr8_-_112248400 0.30 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr3_+_148447887 0.30 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr5_+_95997918 0.30 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST
calpastatin
chr9_-_34665983 0.29 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr4_+_41937131 0.29 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr2_+_113885138 0.29 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr16_+_3508063 0.29 ENST00000576787.1
ENST00000572942.1
ENST00000576916.1
ENST00000575076.1
ENST00000572131.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr7_+_44646218 0.29 ENST00000444676.1
ENST00000222673.5
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr8_-_27469196 0.28 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr11_+_58938903 0.28 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr2_+_191208196 0.28 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_+_204839959 0.27 ENST00000404076.1
NFASC
neurofascin
chr22_-_29711704 0.27 ENST00000216101.6
RASL10A
RAS-like, family 10, member A
chr4_-_74088800 0.27 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr5_+_95997885 0.27 ENST00000511097.2
CAST
calpastatin
chr1_-_156721502 0.26 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr12_+_57624119 0.26 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr9_-_88356789 0.26 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr3_-_196910721 0.26 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_124303472 0.25 ENST00000291478.5
KALRN
kalirin, RhoGEF kinase
chr21_+_35107346 0.25 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr9_-_88356733 0.25 ENST00000376083.3
AGTPBP1
ATP/GTP binding protein 1
chr1_-_167883353 0.25 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr2_+_191208601 0.25 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr12_+_57624085 0.24 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr3_+_169684553 0.24 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr11_+_69061594 0.24 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr20_+_4667094 0.24 ENST00000424424.1
ENST00000457586.1
PRNP
prion protein
chr19_+_1450112 0.23 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr1_-_161087802 0.23 ENST00000368010.3
PFDN2
prefoldin subunit 2
chr1_-_101491319 0.23 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr2_-_167232484 0.23 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr14_-_67826538 0.23 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr2_+_191208656 0.23 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr1_+_154378049 0.22 ENST00000512471.1
IL6R
interleukin 6 receptor
chr8_+_19536083 0.22 ENST00000519803.1
RP11-1105O14.1
RP11-1105O14.1
chr1_+_212738676 0.22 ENST00000366981.4
ENST00000366987.2
ATF3
activating transcription factor 3
chr13_-_45010939 0.21 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr21_+_35736302 0.21 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr8_+_50824233 0.21 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr2_+_198318147 0.20 ENST00000263960.2
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr5_-_54830871 0.20 ENST00000307259.8
PPAP2A
phosphatidic acid phosphatase type 2A
chr19_-_41945804 0.20 ENST00000221943.9
ENST00000597457.1
ENST00000589970.1
ENST00000595425.1
ENST00000438807.3
ENST00000589102.1
ENST00000592922.2
ATP5SL
ATP5S-like
chr12_+_57623869 0.19 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr14_-_72458326 0.19 ENST00000542853.1
AC005477.1
AC005477.1
chr12_+_57623477 0.19 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_-_101801505 0.19 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ARL1
ADP-ribosylation factor-like 1
chr9_+_27524283 0.19 ENST00000276943.2
IFNK
interferon, kappa
chr8_+_90914073 0.18 ENST00000297438.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr17_-_42144949 0.18 ENST00000591247.1
LSM12
LSM12 homolog (S. cerevisiae)
chr17_-_41623009 0.18 ENST00000393664.2
ETV4
ets variant 4
chr4_-_153274078 0.18 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr19_-_46389359 0.18 ENST00000302165.3
IRF2BP1
interferon regulatory factor 2 binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
1.3 5.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
1.1 4.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 3.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.4 3.1 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.4 2.0 GO:1904640 response to methionine(GO:1904640)
0.4 1.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.4 1.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.4 1.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.3 2.4 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.3 2.3 GO:0051012 microtubule sliding(GO:0051012)
0.3 0.9 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.3 1.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 1.0 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 3.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.2 1.8 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 0.6 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 4.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.2 1.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 1.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 2.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 0.6 GO:0002384 hepatic immune response(GO:0002384)
0.2 0.9 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.2 0.6 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 1.9 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.1 0.8 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.6 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 1.2 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.6 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.8 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.9 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 3.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.8 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 1.8 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533) positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.7 GO:0006983 ER overload response(GO:0006983)
0.1 0.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 2.0 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.5 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 1.0 GO:0001558 regulation of cell growth(GO:0001558)
0.1 0.4 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 1.9 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.7 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 2.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.6 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 1.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.3 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.8 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 3.0 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.5 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.2 GO:0007154 cell communication(GO:0007154)
0.0 3.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 1.8 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.9 GO:0065003 macromolecular complex assembly(GO:0065003)
0.0 0.4 GO:0007420 brain development(GO:0007420)
0.0 1.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.7 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 2.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.3 GO:1990742 microvesicle(GO:1990742)
0.2 0.6 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.2 2.2 GO:0016013 syntrophin complex(GO:0016013)
0.1 5.1 GO:0036019 endolysosome(GO:0036019)
0.1 1.3 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.9 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.2 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 1.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 2.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.4 GO:0071942 XPC complex(GO:0071942)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 1.0 GO:0043219 lateral loop(GO:0043219)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 5.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.6 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 3.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 2.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.8 GO:0032420 stereocilium(GO:0032420)
0.0 2.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 2.3 GO:0016605 PML body(GO:0016605)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:0045178 basal part of cell(GO:0045178)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.7 GO:0004882 androgen receptor activity(GO:0004882)
0.6 13.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 1.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.3 2.4 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.3 1.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.2 0.9 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 1.1 GO:0070052 collagen V binding(GO:0070052)
0.2 1.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.9 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 0.6 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.2 GO:0030492 hemoglobin binding(GO:0030492)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 5.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.9 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.2 0.8 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 1.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.2 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 2.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 3.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.0 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.3 GO:1903135 cupric ion binding(GO:1903135)
0.1 0.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 0.6 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 1.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 4.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.7 GO:0004568 chitinase activity(GO:0004568)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.9 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 2.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.4 PID BMP PATHWAY BMP receptor signaling
0.0 4.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 4.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 6.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 3.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.6 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK