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Illumina Body Map 2

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Results for HMBOX1

Z-value: 0.90

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Transcription factors associated with HMBOX1

Gene Symbol Gene ID Gene Info
ENSG00000147421.13 homeobox containing 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMBOX1hg19_v2_chr8_+_28747884_28747938-0.291.0e-01Click!

Activity profile of HMBOX1 motif

Sorted Z-values of HMBOX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_71610985 5.19 ENST00000355962.4
tyrosine aminotransferase
chr20_-_7238861 4.39 ENST00000428954.1
RP11-19D2.1
chr20_+_42187682 4.37 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr20_+_42187608 3.73 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chr6_-_107235331 3.56 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
chr6_-_52668605 2.97 ENST00000334575.5
glutathione S-transferase alpha 1
chr6_-_107235287 2.77 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
chr7_-_120498357 2.75 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr10_+_115312766 2.50 ENST00000351270.3
hyaluronan binding protein 2
chr8_-_63951730 2.41 ENST00000260118.6
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr10_-_54531406 2.34 ENST00000373968.3
mannose-binding lectin (protein C) 2, soluble
chr4_+_187187098 2.24 ENST00000403665.2
ENST00000264692.4
coagulation factor XI
chr6_-_52628271 2.13 ENST00000493422.1
glutathione S-transferase alpha 2
chr9_-_104145795 2.13 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr4_-_110723134 2.07 ENST00000510800.1
ENST00000512148.1
complement factor I
chr4_-_110723194 1.99 ENST00000394635.3
complement factor I
chr8_+_30244580 1.86 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr4_+_156824840 1.76 ENST00000536354.2
tryptophan 2,3-dioxygenase
chr4_-_69434245 1.76 ENST00000317746.2
UDP glucuronosyltransferase 2 family, polypeptide B17
chr10_-_5046042 1.73 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chrM_+_5824 1.65 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr2_+_182850551 1.63 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr11_+_19798964 1.61 ENST00000527559.2
neuron navigator 2
chr4_+_187187337 1.56 ENST00000492972.2
coagulation factor XI
chrX_+_66764375 1.54 ENST00000374690.3
androgen receptor
chr1_+_196743912 1.49 ENST00000367425.4
complement factor H-related 3
chr4_+_74347400 1.48 ENST00000226355.3
afamin
chr1_+_196743943 1.44 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr3_+_119501557 1.41 ENST00000337940.4
nuclear receptor subfamily 1, group I, member 2
chr12_-_33049690 1.34 ENST00000070846.6
ENST00000340811.4
plakophilin 2
chr20_+_61584026 1.32 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr9_+_101984577 1.32 ENST00000223641.4
Sec61 beta subunit
chr2_-_133429091 1.28 ENST00000345008.6
LY6/PLAUR domain containing 1
chr5_+_92919043 1.26 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr12_-_22063787 1.23 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_-_152149033 1.23 ENST00000514152.1
SH3 domain containing 19
chr10_+_89419370 1.21 ENST00000361175.4
ENST00000456849.1
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr15_+_69857515 1.20 ENST00000559477.1
RP11-279F6.1
chr4_-_186877481 1.19 ENST00000444781.1
ENST00000432655.1
sorbin and SH3 domain containing 2
chr19_-_7553852 1.15 ENST00000593547.1
peroxisomal biogenesis factor 11 gamma
chrX_-_10851762 1.14 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr4_-_186877502 1.10 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
sorbin and SH3 domain containing 2
chr6_-_112408661 1.08 ENST00000368662.5
tubulin, epsilon 1
chr1_+_175036966 1.08 ENST00000239462.4
tenascin N
chr12_-_77272765 1.06 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
cysteine and glycine-rich protein 2
chr19_-_7553889 1.05 ENST00000221480.1
peroxisomal biogenesis factor 11 gamma
chr9_+_139377947 1.04 ENST00000354376.1
chromosome 9 open reading frame 163
chr19_+_50084561 1.03 ENST00000246794.5
proline rich Gla (G-carboxyglutamic acid) 2
chr11_+_22694123 1.01 ENST00000534801.1
growth arrest-specific 2
chr18_-_5197501 0.99 ENST00000580650.1
chromosome 18 open reading frame 42
chr2_-_197226875 0.98 ENST00000409111.1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr3_-_149095652 0.98 ENST00000305366.3
transmembrane 4 L six family member 1
chr4_-_140477928 0.97 ENST00000274031.3
SET domain containing (lysine methyltransferase) 7
chr17_-_38083092 0.94 ENST00000394169.1
ORM1-like 3 (S. cerevisiae)
chr11_-_59950519 0.93 ENST00000528851.1
membrane-spanning 4-domains, subfamily A, member 6A
chrX_+_16964985 0.89 ENST00000303843.7
RALBP1 associated Eps domain containing 2
chr7_+_117251671 0.89 ENST00000468795.1
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr11_-_59950622 0.84 ENST00000323961.3
ENST00000412309.2
membrane-spanning 4-domains, subfamily A, member 6A
chr11_-_59950486 0.84 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
membrane-spanning 4-domains, subfamily A, member 6A
chr6_+_123038689 0.79 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr12_+_94071341 0.79 ENST00000542893.2
CASP2 and RIPK1 domain containing adaptor with death domain
chr6_+_112408768 0.79 ENST00000368656.2
ENST00000604268.1
family with sequence similarity 229, member B
chrX_-_15683147 0.78 ENST00000380342.3
transmembrane protein 27
chr6_+_138699042 0.77 ENST00000573100.1
Uncharacterized protein
chr17_-_56494908 0.75 ENST00000577716.1
ring finger protein 43
chr17_-_56494882 0.75 ENST00000584437.1
ring finger protein 43
chr16_-_3422283 0.72 ENST00000399974.3
MT-RNR2-like 4
chr2_-_3521518 0.71 ENST00000382093.5
acireductone dioxygenase 1
chrX_+_114874727 0.71 ENST00000543070.1
plastin 3
chr5_-_133968459 0.69 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1 homolog B (S. cerevisiae)
chr14_+_64854958 0.67 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr11_+_34643600 0.66 ENST00000530286.1
ENST00000533754.1
ets homologous factor
chr10_+_75936444 0.66 ENST00000372734.3
ENST00000541550.1
adenosine kinase
chr1_-_198906528 0.66 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr6_-_52710893 0.66 ENST00000284562.2
glutathione S-transferase alpha 5
chr2_+_159825143 0.65 ENST00000454300.1
ENST00000263635.6
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr1_-_201346761 0.65 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr6_+_138725343 0.64 ENST00000607197.1
ENST00000367697.3
heme binding protein 2
chr6_+_30585486 0.64 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr4_-_114900831 0.62 ENST00000315366.7
arylsulfatase family, member J
chr17_+_41177220 0.62 ENST00000587250.2
ENST00000544533.1
Rho family GTPase 2
chr14_+_75536280 0.62 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr12_-_56236734 0.61 ENST00000548629.1
matrix metallopeptidase 19
chr1_+_170115142 0.59 ENST00000439373.2
methyltransferase like 11B
chr11_-_57194948 0.59 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
solute carrier family 43, member 3
chrX_-_99987088 0.59 ENST00000372981.1
ENST00000263033.5
synaptotagmin-like 4
chr14_+_75536335 0.57 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
zinc finger, C2HC-type containing 1C
chr9_-_101984184 0.57 ENST00000476832.1
ALG2, alpha-1,3/1,6-mannosyltransferase
chr7_+_134576151 0.57 ENST00000393118.2
caldesmon 1
chr17_-_26903900 0.56 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
aldolase C, fructose-bisphosphate
chr11_+_17281900 0.55 ENST00000530527.1
nucleobindin 2
chr11_+_124789146 0.55 ENST00000408930.5
hepatocellular carcinoma, down-regulated 1
chr4_-_140477910 0.54 ENST00000404104.3
SET domain containing (lysine methyltransferase) 7
chr11_+_100862811 0.54 ENST00000303130.2
transmembrane protein 133
chr11_-_111649074 0.52 ENST00000534218.1
RP11-108O10.2
chr1_-_9970383 0.51 ENST00000400904.3
catenin, beta interacting protein 1
chr10_+_60936921 0.51 ENST00000373878.3
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr18_-_19283649 0.51 ENST00000584464.1
ENST00000578270.1
abhydrolase domain containing 3
chr6_-_27114577 0.50 ENST00000356950.1
ENST00000396891.4
histone cluster 1, H2bk
chr8_-_67977178 0.48 ENST00000517736.1
COP9 signalosome subunit 5
chr1_+_207943667 0.46 ENST00000462968.2
CD46 molecule, complement regulatory protein
chrX_+_37208521 0.45 ENST00000378628.4
proline rich Gla (G-carboxyglutamic acid) 1
chr9_+_128510454 0.45 ENST00000491787.3
ENST00000447726.2
pre-B-cell leukemia homeobox 3
chr1_+_219347186 0.44 ENST00000366928.5
lysophospholipase-like 1
chr6_-_51952418 0.43 ENST00000371117.3
polycystic kidney and hepatic disease 1 (autosomal recessive)
chr7_+_90338547 0.43 ENST00000446790.1
cyclin-dependent kinase 14
chr17_-_1395954 0.42 ENST00000359786.5
myosin IC
chr1_+_64669294 0.42 ENST00000371077.5
ubiquitin-conjugating enzyme E2U (putative)
chr7_-_121944491 0.41 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr1_+_219347203 0.41 ENST00000366927.3
lysophospholipase-like 1
chr11_-_57194919 0.40 ENST00000532795.1
solute carrier family 43, member 3
chr12_+_4758264 0.40 ENST00000266544.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr3_+_99904531 0.39 ENST00000429523.2
ENST00000476804.1
transmembrane protein 30C
chr14_-_21566731 0.38 ENST00000360947.3
zinc finger protein 219
chr22_+_17956618 0.38 ENST00000262608.8
cat eye syndrome chromosome region, candidate 2
chr2_+_3800169 0.38 ENST00000399143.3
doublecortin domain containing 2C
chr18_-_5197224 0.37 ENST00000434239.3
chromosome 18 open reading frame 42
chrX_+_70503037 0.37 ENST00000535149.1
non-POU domain containing, octamer-binding
chr17_+_6544078 0.37 ENST00000250101.5
thioredoxin domain containing 17
chr10_+_24755416 0.36 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr22_+_19419425 0.36 ENST00000333130.3
mitochondrial ribosomal protein L40
chr8_-_28347737 0.36 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
F-box protein 16
chr3_-_141747439 0.35 ENST00000467667.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr9_-_73029540 0.35 ENST00000377126.2
Kruppel-like factor 9
chr5_+_55354822 0.35 ENST00000511861.1
CTD-2227I18.1
chr7_-_47579188 0.34 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
tensin 3
chr5_+_131705438 0.34 ENST00000245407.3
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr3_+_147127142 0.34 ENST00000282928.4
Zic family member 1
chr1_+_87595433 0.34 ENST00000469312.2
ENST00000490006.2
long intergenic non-protein coding RNA 1140
chrX_+_70503433 0.33 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
non-POU domain containing, octamer-binding
chr6_-_165989936 0.33 ENST00000354448.4
phosphodiesterase 10A
chr7_+_134576317 0.33 ENST00000424922.1
ENST00000495522.1
caldesmon 1
chr8_+_94710789 0.33 ENST00000523475.1
family with sequence similarity 92, member A1
chr3_-_141747459 0.33 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
transcription factor Dp-2 (E2F dimerization partner 2)
chr4_+_120860695 0.33 ENST00000505122.2
RP11-700N1.1
chr3_-_126327398 0.32 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr16_+_29127282 0.32 ENST00000562902.1
RP11-426C22.5
chr4_-_186682716 0.31 ENST00000445343.1
sorbin and SH3 domain containing 2
chr13_+_24144509 0.31 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr11_+_5474638 0.31 ENST00000341449.2
olfactory receptor, family 51, subfamily I, member 2
chr1_-_217250231 0.30 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr17_+_42925270 0.30 ENST00000253410.2
ENST00000587021.1
HIG1 hypoxia inducible domain family, member 1B
chr3_+_159481988 0.30 ENST00000472451.1
IQCJ-SCHIP1 readthrough
chr1_-_9953295 0.30 ENST00000377258.1
catenin, beta interacting protein 1
chrX_-_10588595 0.29 ENST00000423614.1
ENST00000317552.4
midline 1 (Opitz/BBB syndrome)
chr3_+_159481791 0.29 ENST00000460298.1
IQCJ-SCHIP1 readthrough
chr17_+_3572087 0.29 ENST00000248378.5
ENST00000397133.2
ER membrane protein complex subunit 6
chr6_-_8102714 0.28 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr11_-_57194817 0.28 ENST00000529748.1
ENST00000525474.1
solute carrier family 43, member 3
chr2_-_38604398 0.28 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
atlastin GTPase 2
chr17_-_56609302 0.28 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
septin 4
chr4_-_122302163 0.28 ENST00000394427.2
pyroglutamylated RFamide peptide receptor
chr14_+_105331596 0.27 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
centrosomal protein 170B
chr6_+_134758827 0.27 ENST00000431422.1
long intergenic non-protein coding RNA 1010
chr5_+_125800836 0.27 ENST00000511134.1
GRAM domain containing 3
chr1_-_9970227 0.26 ENST00000377263.1
catenin, beta interacting protein 1
chr17_+_48172639 0.26 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr2_+_128848740 0.26 ENST00000375990.3
UDP-glucose glycoprotein glucosyltransferase 1
chr1_-_93257951 0.26 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
ecotropic viral integration site 5
chr12_-_56727676 0.26 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_-_38326119 0.26 ENST00000356207.5
ENST00000326324.6
fibroblast growth factor receptor 1
chr2_+_127782787 0.26 ENST00000564121.1
RP11-521O16.2
chrX_-_10588459 0.25 ENST00000380782.2
midline 1 (Opitz/BBB syndrome)
chr12_+_49121213 0.25 ENST00000548380.1
long intergenic non-protein coding RNA 935
chr6_+_7108210 0.25 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
ras responsive element binding protein 1
chr5_-_137667526 0.24 ENST00000503022.1
cell division cycle 25C
chr7_-_47578840 0.24 ENST00000450444.1
tensin 3
chr9_-_23779367 0.24 ENST00000440102.1
ELAV like neuron-specific RNA binding protein 2
chr10_-_94257512 0.23 ENST00000371581.5
insulin-degrading enzyme
chr14_+_21458127 0.23 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
methyltransferase like 17
chr2_-_99952769 0.23 ENST00000409434.1
ENST00000434323.1
ENST00000264255.3
thioredoxin domain containing 9
chr1_+_198126209 0.23 ENST00000367383.1
NIMA-related kinase 7
chr7_-_116607526 0.23 ENST00000420664.1
Uncharacterized protein
chr7_-_16505440 0.23 ENST00000307068.4
sclerostin domain containing 1
chr8_-_67874805 0.22 ENST00000563496.1
transcription factor 24
chr7_+_107220899 0.22 ENST00000379117.2
ENST00000473124.1
B-cell receptor-associated protein 29
chr2_+_162087577 0.22 ENST00000439442.1
TRAF family member-associated NFKB activator
chr8_-_38326139 0.21 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
fibroblast growth factor receptor 1
chr1_-_217311090 0.20 ENST00000493603.1
ENST00000366940.2
estrogen-related receptor gamma
chr5_-_137667459 0.20 ENST00000415130.2
ENST00000356505.3
ENST00000357274.3
ENST00000348983.3
ENST00000323760.6
cell division cycle 25C
chr11_+_66115304 0.20 ENST00000531602.1
Uncharacterized protein
chrX_+_37208540 0.20 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr12_-_53715328 0.20 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
achalasia, adrenocortical insufficiency, alacrimia
chr1_+_100436065 0.19 ENST00000370153.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chrX_-_69509738 0.19 ENST00000374454.1
ENST00000239666.4
PDZ domain containing 11
chr7_+_128379449 0.19 ENST00000479257.1
calumenin
chr14_+_45431379 0.19 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
family with sequence similarity 179, member B
chr12_-_56727487 0.18 ENST00000548043.1
ENST00000425394.2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_22234381 0.18 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr7_+_95115210 0.18 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr2_+_204193101 0.17 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
abl-interactor 2
chr10_-_24911746 0.17 ENST00000320481.6
Rho GTPase activating protein 21
chr11_+_57531292 0.17 ENST00000524579.1
catenin (cadherin-associated protein), delta 1
chr4_+_118955635 0.17 ENST00000433996.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr19_-_56826157 0.17 ENST00000592509.1
ENST00000592679.1
ENST00000588442.1
ENST00000593106.1
ENST00000587492.1
ENST00000254165.3
zinc finger and SCAN domain containing 5A
chr20_+_59654146 0.17 ENST00000441660.1
RP5-827L5.1
chr11_-_124981475 0.17 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr17_-_27621125 0.17 ENST00000579665.1
ENST00000225388.4
nuclear fragile X mental retardation protein interacting protein 2
chr15_+_75639296 0.17 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
nei endonuclease VIII-like 1 (E. coli)
chr14_+_32030582 0.17 ENST00000550649.1
ENST00000281081.7
nucleotide binding protein-like

Network of associatons between targets according to the STRING database.

First level regulatory network of HMBOX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.8 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 2.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.6 5.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.5 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.4 1.8 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 1.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.3 1.2 GO:0000103 sulfate assimilation(GO:0000103)
0.3 2.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 1.3 GO:0048496 adherens junction maintenance(GO:0034334) maintenance of organ identity(GO:0048496)
0.3 1.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.2 0.9 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.2 0.7 GO:0044209 AMP salvage(GO:0044209)
0.2 1.7 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 1.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.2 0.9 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.2 2.3 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.2 1.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.2 1.6 GO:0021564 vagus nerve development(GO:0021564)
0.2 2.1 GO:0019530 taurine metabolic process(GO:0019530)
0.2 0.6 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.5 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.2 1.4 GO:0046618 drug export(GO:0046618)
0.1 0.4 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.6 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.7 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 4.8 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.3 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 1.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.7 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0097359 UDP-glucosylation(GO:0097359)
0.1 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.8 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.4 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.6 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.1 1.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 2.8 GO:0010842 retina layer formation(GO:0010842)
0.1 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 1.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.6 GO:0001554 luteolysis(GO:0001554)
0.1 0.2 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 7.9 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 2.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.2 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 1.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.5 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 1.3 GO:1905144 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.5 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 3.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 1.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 1.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.9 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 0.9 GO:0035339 SPOTS complex(GO:0035339)
0.2 1.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 1.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.4 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 0.5 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.9 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:1903349 omegasome membrane(GO:1903349)
0.1 1.9 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.0 1.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 1.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.0 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.4 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 4.4 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 1.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.4 1.5 GO:0008431 vitamin E binding(GO:0008431)
0.3 1.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.3 1.8 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.3 9.0 GO:0017081 chloride channel regulator activity(GO:0017081)
0.3 1.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 1.5 GO:0004882 androgen receptor activity(GO:0004882)
0.2 1.7 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 0.7 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.2 0.7 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.6 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.6 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 2.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.9 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.1 2.3 GO:0005537 mannose binding(GO:0005537)
0.1 2.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 5.8 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 1.3 GO:0019215 intermediate filament binding(GO:0019215)
0.1 2.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.6 GO:0030172 troponin C binding(GO:0030172)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.8 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 2.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.7 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 1.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.8 GO:0070513 death domain binding(GO:0070513)
0.0 1.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.9 GO:0005523 tropomyosin binding(GO:0005523)
0.0 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.3 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.7 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 1.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 3.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 5.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.0 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 4.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 5.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport