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Illumina Body Map 2

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Results for HMGA1

Z-value: 1.37

Motif logo

Transcription factors associated with HMGA1

Gene Symbol Gene ID Gene Info
ENSG00000137309.15 high mobility group AT-hook 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HMGA1hg19_v2_chr6_+_34204642_34204664-0.173.6e-01Click!

Activity profile of HMGA1 motif

Sorted Z-values of HMGA1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_115423792 5.87 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
nebulin-related anchoring protein
chr12_-_111358372 5.16 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr5_+_137203465 3.97 ENST00000239926.4
myotilin
chr14_+_32798462 3.90 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr5_+_137203541 3.89 ENST00000421631.2
myotilin
chr5_+_137203557 3.88 ENST00000515645.1
myotilin
chr12_+_101988627 3.82 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr10_-_4285923 3.79 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr10_-_4285835 3.63 ENST00000454470.1
long intergenic non-protein coding RNA 702
chr2_+_1418154 3.59 ENST00000423320.1
ENST00000382198.1
thyroid peroxidase
chr14_+_32798547 3.54 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr8_+_79503458 3.54 ENST00000518467.1
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr4_+_41540160 3.22 ENST00000503057.1
ENST00000511496.1
LIM and calponin homology domains 1
chr6_+_53883708 3.19 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr5_+_145316120 3.18 ENST00000359120.4
SH3 domain containing ring finger 2
chrX_-_73072534 3.13 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr2_-_152589670 3.07 ENST00000604864.1
ENST00000603639.1
nebulin
chr6_-_53530474 3.00 ENST00000370905.3
kelch-like family member 31
chr7_-_81635106 2.94 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chrX_-_15333775 2.90 ENST00000480796.1
ankyrin repeat and SOCS box containing 11
chr3_-_57326704 2.67 ENST00000487349.1
ENST00000389601.3
ankyrin repeat and SOCS box containing 14
chrX_-_15332665 2.50 ENST00000537676.1
ENST00000344384.4
ankyrin repeat and SOCS box containing 11
chr10_-_69455873 2.45 ENST00000433211.2
catenin (cadherin-associated protein), alpha 3
chr3_-_195310802 2.44 ENST00000421243.1
ENST00000453131.1
apolipoprotein D
chr6_+_53883790 2.40 ENST00000509997.1
muscular LMNA-interacting protein
chrX_-_15333736 2.39 ENST00000380470.3
ankyrin repeat and SOCS box containing 11
chr8_-_82395461 2.34 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr7_+_123241908 2.28 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chr4_-_177190364 2.24 ENST00000296525.3
ankyrin repeat and SOCS box containing 5
chr18_+_32290218 2.24 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
dystrobrevin, alpha
chr11_+_1940925 2.22 ENST00000453458.1
ENST00000381557.2
ENST00000381589.3
ENST00000381579.3
ENST00000381563.4
ENST00000344578.4
troponin T type 3 (skeletal, fast)
chr6_-_139613269 2.16 ENST00000358430.3
taxilin beta
chr1_+_78383813 2.14 ENST00000342754.5
nexilin (F actin binding protein)
chr12_+_101962128 2.12 ENST00000550514.1
myosin binding protein C, slow type
chr12_+_101988774 2.10 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr6_+_53948328 2.09 ENST00000370876.2
muscular LMNA-interacting protein
chr12_+_12938541 2.07 ENST00000356591.4
apolipoprotein L domain containing 1
chr2_-_100925967 2.00 ENST00000409647.1
LON peptidase N-terminal domain and ring finger 2
chr9_+_103340354 1.99 ENST00000307584.5
muscle-related coiled-coil protein
chr2_-_211168332 1.98 ENST00000341685.4
myosin, light chain 1, alkali; skeletal, fast
chr9_+_71944241 1.96 ENST00000257515.8
family with sequence similarity 189, member A2
chr17_-_10452929 1.86 ENST00000532183.2
ENST00000397183.2
ENST00000420805.1
myosin, heavy chain 2, skeletal muscle, adult
chr12_+_28605426 1.85 ENST00000542801.1
coiled-coil domain containing 91
chrX_+_99839799 1.85 ENST00000373031.4
tenomodulin
chr3_-_196242233 1.81 ENST00000397537.2
single-pass membrane protein with coiled-coil domains 1
chr4_-_22444733 1.80 ENST00000508133.1
G protein-coupled receptor 125
chr13_+_23755054 1.78 ENST00000218867.3
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr10_-_69425399 1.77 ENST00000330298.6
catenin (cadherin-associated protein), alpha 3
chr3_+_135684515 1.74 ENST00000264977.3
ENST00000490467.1
protein phosphatase 2, regulatory subunit B'', alpha
chr12_+_21207503 1.73 ENST00000545916.1
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr11_-_111781554 1.72 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr2_+_103378472 1.72 ENST00000412401.2
transmembrane protein 182
chr9_+_77230499 1.69 ENST00000396204.2
RAR-related orphan receptor B
chr5_+_140557371 1.68 ENST00000239444.2
protocadherin beta 8
chr16_+_7560114 1.67 ENST00000570626.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_186578674 1.63 ENST00000438278.1
sorbin and SH3 domain containing 2
chr12_+_122880045 1.63 ENST00000539034.1
ENST00000535976.1
RP11-450K4.1
chr12_-_22063787 1.62 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_-_88180342 1.60 ENST00000502983.1
myocyte enhancer factor 2C
chr5_+_140593509 1.58 ENST00000341948.4
protocadherin beta 13
chr13_+_76378305 1.56 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr21_+_35552978 1.55 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
long intergenic non-protein coding RNA 310
chr4_-_177162822 1.54 ENST00000512254.1
ankyrin repeat and SOCS box containing 5
chr5_-_41794663 1.50 ENST00000510634.1
3-oxoacid CoA transferase 1
chr7_+_15728003 1.50 ENST00000442176.1
AC005550.4
chr3_+_69811858 1.50 ENST00000433517.1
microphthalmia-associated transcription factor
chr1_-_100643765 1.49 ENST00000370137.1
ENST00000370138.1
ENST00000342895.3
leucine rich repeat containing 39
chr12_-_71551652 1.47 ENST00000546561.1
tetraspanin 8
chr12_-_91573249 1.46 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr3_-_46608010 1.44 ENST00000395905.3
leucine rich repeat containing 2
chr9_+_71986182 1.43 ENST00000303068.7
family with sequence similarity 189, member A2
chrX_-_73061339 1.42 ENST00000602863.1
X inactive specific transcript (non-protein coding)
chrX_-_33357558 1.41 ENST00000288447.4
dystrophin
chr15_-_99789736 1.40 ENST00000560235.1
ENST00000394132.2
ENST00000560860.1
ENST00000558078.1
ENST00000394136.1
ENST00000262074.4
ENST00000558613.1
ENST00000394130.1
ENST00000560772.1
tetratricopeptide repeat domain 23
chr2_-_217560248 1.40 ENST00000233813.4
insulin-like growth factor binding protein 5
chr1_-_178838404 1.39 ENST00000444255.1
angiopoietin-like 1
chr5_+_61874562 1.38 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr1_-_154458520 1.37 ENST00000486773.1
Src homology 2 domain containing E
chr4_+_78804393 1.37 ENST00000502384.1
mitochondrial ribosomal protein L1
chrX_-_15619076 1.37 ENST00000252519.3
angiotensin I converting enzyme 2
chr13_+_30002741 1.36 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr10_-_75226166 1.36 ENST00000544628.1
protein phosphatase 3, catalytic subunit, beta isozyme
chr12_+_80750652 1.35 ENST00000550182.1
otogelin-like
chr4_+_169575875 1.34 ENST00000503457.1
palladin, cytoskeletal associated protein
chr4_-_138453606 1.34 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr4_-_152147579 1.33 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3 domain containing 19
chr12_-_10978957 1.32 ENST00000240619.2
taste receptor, type 2, member 10
chr11_-_13517565 1.32 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr4_+_74301880 1.31 ENST00000395792.2
ENST00000226359.2
alpha-fetoprotein
chr1_-_231005310 1.31 ENST00000470540.1
chromosome 1 open reading frame 198
chr13_-_47471155 1.30 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr4_+_71494461 1.30 ENST00000396073.3
enamelin
chr9_+_96846740 1.28 ENST00000288976.3
protein tyrosine phosphatase domain containing 1
chr4_-_164265984 1.25 ENST00000511901.1
neuropeptide Y receptor Y1
chr4_-_16675930 1.24 ENST00000503178.2
LIM domain binding 2
chr13_-_38172863 1.24 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
periostin, osteoblast specific factor
chr10_-_116444371 1.24 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr12_-_86650045 1.22 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr11_+_100784231 1.22 ENST00000531183.1
Rho GTPase activating protein 42
chr9_-_47314222 1.22 ENST00000420228.1
ENST00000438517.1
ENST00000414020.1
AL953854.2
chr6_-_76072719 1.22 ENST00000370020.1
filamin A interacting protein 1
chr6_-_46293378 1.21 ENST00000330430.6
regulator of calcineurin 2
chr12_-_122879969 1.20 ENST00000540304.1
CAP-GLY domain containing linker protein 1
chr8_-_52721975 1.19 ENST00000356297.4
ENST00000543296.1
peroxidasin homolog (Drosophila)-like
chr12_+_110718428 1.18 ENST00000552636.1
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr15_+_80733570 1.18 ENST00000533983.1
ENST00000527771.1
ENST00000525103.1
aryl-hydrocarbon receptor nuclear translocator 2
chr18_+_28898052 1.17 ENST00000257192.4
desmoglein 1
chr7_-_129691201 1.17 ENST00000480193.1
ENST00000360708.5
ENST00000311873.5
ENST00000481503.1
ENST00000358303.4
zinc finger, C3HC-type containing 1
chr2_+_239047337 1.17 ENST00000409223.1
ENST00000305959.4
kelch-like family member 30
chr11_+_22696314 1.16 ENST00000532398.1
ENST00000433790.1
growth arrest-specific 2
chr1_+_52682052 1.15 ENST00000371591.1
zinc finger, FYVE domain containing 9
chr5_+_140705777 1.14 ENST00000606901.1
ENST00000606674.1
AC005618.6
chr4_+_159131596 1.14 ENST00000512481.1
transmembrane protein 144
chr9_+_13446472 1.13 ENST00000428006.2
RP11-536O18.1
chr1_+_178310581 1.13 ENST00000462775.1
RAS protein activator like 2
chr15_-_28419569 1.13 ENST00000569772.1
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr12_-_86650077 1.12 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr9_-_21187598 1.11 ENST00000421715.1
interferon, alpha 4
chr18_+_68002675 1.11 ENST00000584919.1
Uncharacterized protein
chr1_+_196621002 1.10 ENST00000367429.4
ENST00000439155.2
complement factor H
chr19_-_7167989 1.10 ENST00000600492.1
insulin receptor
chr3_-_155011483 1.10 ENST00000489090.1
RP11-451G4.2
chr17_-_10372875 1.09 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr4_-_186696425 1.09 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr6_-_119031228 1.09 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
centrosomal protein 85kDa-like
chr12_-_54653313 1.08 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chrX_+_103031421 1.08 ENST00000433491.1
ENST00000418604.1
ENST00000443502.1
proteolipid protein 1
chr10_+_24498060 1.06 ENST00000376454.3
ENST00000376452.3
KIAA1217
chr8_-_17555164 1.06 ENST00000297488.6
microtubule associated tumor suppressor 1
chr9_+_108463234 1.05 ENST00000374688.1
transmembrane protein 38B
chrX_-_33146477 1.04 ENST00000378677.2
dystrophin
chr6_+_153552455 1.04 ENST00000392385.2
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr5_+_140739537 1.04 ENST00000522605.1
protocadherin gamma subfamily B, 2
chr19_+_34891252 1.03 ENST00000606020.1
Uncharacterized protein
chr11_-_101778665 1.03 ENST00000534527.1
angiopoietin-like 5
chr3_+_158787041 1.03 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1 readthrough
chr12_-_91574142 1.03 ENST00000547937.1
decorin
chr4_+_110834033 1.03 ENST00000509793.1
ENST00000265171.5
epidermal growth factor
chr14_-_35182994 1.03 ENST00000341223.3
cofilin 2 (muscle)
chr15_+_54305101 1.02 ENST00000260323.11
ENST00000545554.1
ENST00000537900.1
unc-13 homolog C (C. elegans)
chr1_-_178840157 1.01 ENST00000367629.1
ENST00000234816.2
angiopoietin-like 1
chr3_+_159557637 1.00 ENST00000445224.2
schwannomin interacting protein 1
chrX_-_33229636 1.00 ENST00000357033.4
dystrophin
chr4_-_186696515 1.00 ENST00000456596.1
ENST00000414724.1
sorbin and SH3 domain containing 2
chr3_+_69812701 0.98 ENST00000472437.1
microphthalmia-associated transcription factor
chr4_+_70796784 0.97 ENST00000246891.4
ENST00000444405.3
casein alpha s1
chr2_-_218770168 0.96 ENST00000413554.1
tensin 1
chr4_+_95376396 0.95 ENST00000508216.1
ENST00000514743.1
PDZ and LIM domain 5
chr8_-_26724784 0.95 ENST00000380573.3
adrenoceptor alpha 1A
chr1_+_202431859 0.94 ENST00000391959.3
ENST00000367270.4
protein phosphatase 1, regulatory subunit 12B
chr7_-_120498357 0.94 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr5_-_142023766 0.94 ENST00000394496.2
fibroblast growth factor 1 (acidic)
chr13_+_109248500 0.94 ENST00000356711.2
myosin XVI
chr3_-_196911002 0.93 ENST00000452595.1
discs, large homolog 1 (Drosophila)
chr2_-_227050079 0.93 ENST00000423838.1
AC068138.1
chr8_-_112039643 0.93 ENST00000524283.1
RP11-946L20.2
chr10_-_5046042 0.93 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr18_-_70532906 0.92 ENST00000299430.2
ENST00000397929.1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_116654958 0.92 ENST00000449366.1
suppression of tumorigenicity 7
chr17_-_66951474 0.92 ENST00000269080.2
ATP-binding cassette, sub-family A (ABC1), member 8
chr13_+_76413852 0.92 ENST00000533809.2
LIM domain 7
chr2_+_189839046 0.91 ENST00000304636.3
ENST00000317840.5
collagen, type III, alpha 1
chr19_-_57967854 0.91 ENST00000321039.3
vomeronasal 1 receptor 1
chr2_+_86333340 0.89 ENST00000409783.2
ENST00000409277.3
pentatricopeptide repeat domain 3
chr6_-_56492816 0.89 ENST00000522360.1
dystonin
chr11_-_105010320 0.88 ENST00000532895.1
ENST00000530950.1
caspase recruitment domain family, member 18
chr6_+_97010424 0.88 ENST00000541107.1
ENST00000450218.1
ENST00000326771.2
four and a half LIM domains 5
chr2_+_29353520 0.88 ENST00000438819.1
CAP-GLY domain containing linker protein family, member 4
chr4_-_100212132 0.88 ENST00000209668.2
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr12_+_19358192 0.88 ENST00000538305.1
pleckstrin homology domain containing, family A member 5
chr12_+_96196875 0.87 ENST00000553095.1
Uncharacterized protein
chr18_+_18943554 0.87 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr7_+_116654935 0.87 ENST00000432298.1
ENST00000422922.1
suppression of tumorigenicity 7
chr3_+_69915385 0.87 ENST00000314589.5
microphthalmia-associated transcription factor
chr12_-_87232644 0.86 ENST00000549405.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr21_-_35284635 0.86 ENST00000429238.1
AP000304.12
chr11_-_56000737 0.86 ENST00000313264.4
olfactory receptor, family 5, subfamily T, member 2
chr6_+_78400375 0.86 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr14_-_90085458 0.85 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr12_-_86650154 0.85 ENST00000552435.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_186696561 0.85 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
sorbin and SH3 domain containing 2
chr4_-_110723134 0.85 ENST00000510800.1
ENST00000512148.1
complement factor I
chr7_+_75932863 0.85 ENST00000429938.1
heat shock 27kDa protein 1
chr18_-_25616519 0.84 ENST00000399380.3
cadherin 2, type 1, N-cadherin (neuronal)
chrX_+_10126488 0.84 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
chloride channel, voltage-sensitive 4
chr8_-_110620284 0.83 ENST00000529690.1
syntabulin (syntaxin-interacting)
chr4_-_186877806 0.83 ENST00000355634.5
sorbin and SH3 domain containing 2
chr14_-_53331239 0.83 ENST00000553663.1
fermitin family member 2
chr2_+_29001711 0.82 ENST00000418910.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr5_-_41794313 0.82 ENST00000512084.1
3-oxoacid CoA transferase 1
chrX_+_85969626 0.82 ENST00000484479.1
dachshund homolog 2 (Drosophila)
chr2_+_17721937 0.81 ENST00000451533.1
visinin-like 1
chr5_-_107703556 0.81 ENST00000496714.1
F-box and leucine-rich repeat protein 17
chr8_-_62559366 0.81 ENST00000522919.1
aspartate beta-hydroxylase
chr16_-_49890016 0.81 ENST00000563137.2
zinc finger protein 423
chr4_-_100242549 0.80 ENST00000305046.8
ENST00000394887.3
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_+_173116225 0.79 ENST00000457714.1
neuroligin 1
chrX_-_80457385 0.79 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chr14_-_73360796 0.79 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
D4, zinc and double PHD fingers, family 3
chr13_+_113633620 0.78 ENST00000421756.1
ENST00000375601.3
MCF.2 cell line derived transforming sequence-like

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.6 3.1 GO:0007525 somatic muscle development(GO:0007525)
0.6 2.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.5 5.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.5 1.4 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.4 1.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 1.2 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.4 2.9 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.4 8.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 1.4 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.3 2.4 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 2.7 GO:0046952 ketone body catabolic process(GO:0046952)
0.3 4.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.3 2.6 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 0.9 GO:0003099 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.3 2.0 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.3 1.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.3 3.5 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 1.8 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.3 1.3 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.2 1.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 0.7 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.2 3.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 0.7 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.2 0.7 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.2 1.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.2 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 1.2 GO:1990523 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)
0.2 1.0 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.2 0.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.8 GO:0099543 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942) trans-synaptic signaling by soluble gas(GO:0099543)
0.2 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.5 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.2 1.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2 0.5 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.2 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 0.7 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 0.7 GO:0044691 tooth eruption(GO:0044691)
0.2 1.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.0 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.2 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.2 0.6 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 3.5 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 2.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.2 1.8 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.4 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.7 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.7 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.4 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 6.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 5.6 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 2.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.4 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.4 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.6 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.7 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.9 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.9 GO:0019236 response to pheromone(GO:0019236)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 0.8 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 3.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 7.2 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 0.2 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.1 2.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0061569 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.7 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.0 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.3 GO:0042245 RNA repair(GO:0042245)
0.1 0.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.9 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.7 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 2.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.8 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.2 GO:0060221 retinal rod cell differentiation(GO:0060221) negative regulation of neuromuscular junction development(GO:1904397)
0.1 1.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.6 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 1.8 GO:0061458 reproductive system development(GO:0061458)
0.1 4.7 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.3 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 1.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 2.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.6 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 1.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 1.3 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.6 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.1 0.9 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.9 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 1.0 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 2.2 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 1.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.8 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.9 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.7 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 1.0 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.6 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 1.4 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.6 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 4.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.5 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 1.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 6.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:2000329 negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.4 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:2000821 regulation of grooming behavior(GO:2000821)
0.0 0.4 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 2.6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:0001806 type IV hypersensitivity(GO:0001806) regulation of type IV hypersensitivity(GO:0001807) negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.4 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 12.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 3.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 1.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 21.0 GO:0043687 post-translational protein modification(GO:0043687)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.8 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.7 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0009650 UV protection(GO:0009650)
0.0 0.8 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.6 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.3 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.6 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.7 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.4 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.4 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 1.5 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.4 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.4 GO:0031175 neuron projection development(GO:0031175)
0.0 0.5 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 2.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 1.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 1.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.6 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0060134 prepulse inhibition(GO:0060134)
0.0 2.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.6 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 1.8 GO:0060047 heart process(GO:0003015) heart contraction(GO:0060047)
0.0 0.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 3.0 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 1.8 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.9 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0050954 sensory perception of sound(GO:0007605) sensory perception of mechanical stimulus(GO:0050954)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0001955 blood vessel maturation(GO:0001955)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.9 GO:0005927 muscle tendon junction(GO:0005927)
0.4 7.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.4 6.9 GO:0097512 cardiac myofibril(GO:0097512)
0.4 11.0 GO:0032982 myosin filament(GO:0032982)
0.3 2.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.3 3.3 GO:0016013 syntrophin complex(GO:0016013)
0.3 4.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 0.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 4.7 GO:0005916 fascia adherens(GO:0005916)
0.2 1.3 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.2 1.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 1.6 GO:0070852 cell body fiber(GO:0070852)
0.2 0.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.7 GO:0044305 calyx of Held(GO:0044305)
0.2 2.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.1 GO:0005899 insulin receptor complex(GO:0005899)
0.2 1.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.9 GO:0031673 H zone(GO:0031673)
0.1 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.4 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.4 GO:0036117 hyaluranon cable(GO:0036117)
0.1 28.7 GO:0030018 Z disc(GO:0030018)
0.1 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.4 GO:0005584 collagen type I trimer(GO:0005584)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 3.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 0.6 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 1.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 0.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.3 GO:0030478 actin cap(GO:0030478)
0.1 1.2 GO:0097470 ribbon synapse(GO:0097470)
0.1 1.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.9 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0097433 dense body(GO:0097433)
0.0 5.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 1.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.8 GO:0031674 I band(GO:0031674)
0.0 0.9 GO:0000800 lateral element(GO:0000800)
0.0 1.1 GO:0005925 focal adhesion(GO:0005925)
0.0 1.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 6.3 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 9.1 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.4 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 2.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 5.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.6 GO:0060076 excitatory synapse(GO:0060076)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.6 2.3 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.6 2.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 3.6 GO:0004447 iodide peroxidase activity(GO:0004447)
0.4 15.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 1.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 1.2 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.4 7.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.3 3.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 10.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.3 0.9 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.3 0.9 GO:0016503 pheromone receptor activity(GO:0016503)
0.3 1.5 GO:0070052 collagen V binding(GO:0070052)
0.3 2.0 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.3 5.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.3 0.8 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 0.7 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.2 0.7 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.2 3.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.4 GO:0008494 translation activator activity(GO:0008494)
0.2 0.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 2.6 GO:0097016 L27 domain binding(GO:0097016)
0.2 0.8 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.2 0.6 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.2 1.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.8 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.0 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.2 0.8 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.2 0.5 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 1.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.2 16.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 0.6 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.2 2.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 3.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.7 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.9 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 3.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.5 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.4 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.4 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.2 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 1.3 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.3 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 1.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 3.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0004522 ribonuclease A activity(GO:0004522)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.6 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 2.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.3 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.2 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 1.6 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 1.3 GO:0042805 actinin binding(GO:0042805)
0.1 1.0 GO:0042731 PH domain binding(GO:0042731)
0.1 0.7 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.9 GO:0089720 caspase binding(GO:0089720)
0.1 0.9 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 1.0 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 6.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 2.9 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 1.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 2.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 0.8 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.2 GO:0070538 oleic acid binding(GO:0070538)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 4.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 1.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 2.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.9 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 1.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0070283 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.1 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.1 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 2.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0033677 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.0 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 13.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.7 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0016594 glycine binding(GO:0016594)
0.0 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.6 GO:0016740 transferase activity(GO:0016740)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0000339 RNA cap binding(GO:0000339)
0.0 2.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.2 GO:0008143 poly(A) binding(GO:0008143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 5.2 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 3.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.9 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 21.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 3.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 2.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.5 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 2.7 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 1.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.9 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 17.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.3 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends