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Illumina Body Map 2
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Results for HNF4G
Z-value: 2.11
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Transcription factors associated with HNF4G
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HNF4G | hg19_v2_chr8_+_76452097_76452126 | 0.54 | 1.4e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_41356347 Show fit | 19.22 |
ENST00000301141.5
|
cytochrome P450, family 2, subfamily A, polypeptide 6 |
|
| chrX_+_138612889 Show fit | 13.55 |
ENST00000218099.2
ENST00000394090.2 |
coagulation factor IX |
|
| chr12_+_57828521 Show fit | 11.56 |
ENST00000309668.2
|
inhibin, beta C |
|
| chr7_-_100239132 Show fit | 10.28 |
ENST00000223051.3
ENST00000431692.1 |
transferrin receptor 2 |
|
| chr10_-_129691195 Show fit | 9.69 |
ENST00000368671.3
|
clarin 3 |
|
| chr2_+_241807870 Show fit | 9.18 |
ENST00000307503.3
|
alanine-glyoxylate aminotransferase |
|
| chr11_-_116694009 Show fit | 8.15 |
ENST00000357780.3
|
apolipoprotein A-IV |
|
| chr10_-_96829246 Show fit | 8.05 |
ENST00000371270.3
ENST00000535898.1 ENST00000539050.1 |
cytochrome P450, family 2, subfamily C, polypeptide 8 |
|
| chr13_+_113760098 Show fit | 7.72 |
ENST00000346342.3
ENST00000541084.1 ENST00000375581.3 |
coagulation factor VII (serum prothrombin conversion accelerator) |
|
| chr3_+_52812523 Show fit | 7.22 |
ENST00000540715.1
|
inter-alpha-trypsin inhibitor heavy chain 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of HNF4G
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 31.1 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 3.0 | 24.0 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 6.0 | 23.9 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.4 | 16.6 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 3.2 | 16.2 | GO:0010902 | positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902) |
| 3.2 | 16.0 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
| 0.2 | 15.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 3.1 | 15.4 | GO:0006524 | alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) |
| 2.9 | 14.4 | GO:0009440 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.2 | 14.1 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 43.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.5 | 35.3 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 33.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 3.2 | 28.6 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 0.2 | 26.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.2 | 21.7 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
| 0.0 | 20.3 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 19.5 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.2 | 19.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 14.8 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 54.4 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 32.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.5 | 24.7 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 2.3 | 16.2 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.4 | 14.7 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 0.2 | 14.7 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 14.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 13.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 1.6 | 12.7 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 3.1 | 12.5 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 42.8 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 32.7 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.3 | 29.5 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 8.0 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.2 | 6.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 6.4 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 4.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 4.2 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 4.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.2 | 3.9 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 54.4 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.2 | 53.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 1.1 | 32.1 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.5 | 28.5 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 1.5 | 27.7 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.5 | 20.2 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.2 | 13.6 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 11.9 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.4 | 11.6 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.8 | 11.0 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |