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Illumina Body Map 2

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Results for HNF4G

Z-value: 2.11

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Transcription factors associated with HNF4G

Gene Symbol Gene ID Gene Info
ENSG00000164749.7 hepatocyte nuclear factor 4 gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HNF4Ghg19_v2_chr8_+_76452097_764521260.541.4e-03Click!

Activity profile of HNF4G motif

Sorted Z-values of HNF4G motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_41356347 19.22 ENST00000301141.5
cytochrome P450, family 2, subfamily A, polypeptide 6
chrX_+_138612889 13.55 ENST00000218099.2
ENST00000394090.2
coagulation factor IX
chr12_+_57828521 11.56 ENST00000309668.2
inhibin, beta C
chr7_-_100239132 10.28 ENST00000223051.3
ENST00000431692.1
transferrin receptor 2
chr10_-_129691195 9.69 ENST00000368671.3
clarin 3
chr2_+_241807870 9.18 ENST00000307503.3
alanine-glyoxylate aminotransferase
chr11_-_116694009 8.15 ENST00000357780.3
apolipoprotein A-IV
chr10_-_96829246 8.05 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr13_+_113760098 7.72 ENST00000346342.3
ENST00000541084.1
ENST00000375581.3
coagulation factor VII (serum prothrombin conversion accelerator)
chr3_+_52812523 7.22 ENST00000540715.1
inter-alpha-trypsin inhibitor heavy chain 1
chr16_-_56701933 6.86 ENST00000568675.1
ENST00000569500.1
ENST00000444837.2
ENST00000379811.3
metallothionein 1G
chr3_-_52860850 6.76 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr12_-_21757774 6.71 ENST00000261195.2
glycogen synthase 2 (liver)
chr6_+_131148538 6.70 ENST00000541421.2
small leucine-rich protein 1
chr11_+_116700614 6.62 ENST00000375345.1
apolipoprotein C-III
chr3_-_42917363 6.61 ENST00000437102.1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr17_-_7082668 6.40 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chr6_+_131894284 6.38 ENST00000368087.3
ENST00000356962.2
arginase 1
chr11_-_624926 6.36 ENST00000526077.1
ENST00000534311.1
ENST00000531088.1
ENST00000397542.2
cadherin-related family member 5
chr10_+_96443378 6.35 ENST00000285979.6
cytochrome P450, family 2, subfamily C, polypeptide 18
chr19_-_51017127 6.29 ENST00000389208.4
aspartate dehydrogenase domain containing
chr12_+_109273806 6.24 ENST00000228476.3
ENST00000547768.1
D-amino-acid oxidase
chr9_+_139839711 6.12 ENST00000224181.3
complement component 8, gamma polypeptide
chr11_+_116700600 5.85 ENST00000227667.3
apolipoprotein C-III
chr11_-_625163 5.81 ENST00000349570.7
cadherin-related family member 5
chr19_-_41388657 5.73 ENST00000301146.4
ENST00000291764.3
cytochrome P450, family 2, subfamily A, polypeptide 7
chr22_-_42526802 5.71 ENST00000359033.4
ENST00000389970.3
ENST00000360608.5
cytochrome P450, family 2, subfamily D, polypeptide 6
chr19_+_45449266 5.63 ENST00000592257.1
apolipoprotein C-II
chr1_+_207262578 5.60 ENST00000243611.5
ENST00000367076.3
complement component 4 binding protein, beta
chr17_+_27369918 5.60 ENST00000323372.4
pipecolic acid oxidase
chr10_+_96522361 5.53 ENST00000371321.3
cytochrome P450, family 2, subfamily C, polypeptide 19
chr10_+_96443204 5.44 ENST00000339022.5
cytochrome P450, family 2, subfamily C, polypeptide 18
chr9_+_139839686 5.38 ENST00000371634.2
complement component 8, gamma polypeptide
chr19_+_45449228 5.33 ENST00000252490.4
apolipoprotein C-II
chr19_+_45449301 5.21 ENST00000591597.1
apolipoprotein C-II
chr1_-_177939041 5.20 ENST00000308284.6
SEC16 homolog B (S. cerevisiae)
chr17_-_7082861 5.17 ENST00000269299.3
asialoglycoprotein receptor 1
chr2_+_242750274 5.11 ENST00000405370.1
sialidase 4
chr3_-_126236605 5.09 ENST00000290868.2
urocanate hydratase 1
chr6_+_43265992 5.08 ENST00000449231.1
ENST00000372589.3
ENST00000372585.5
solute carrier family 22 (organic anion transporter), member 7
chr1_-_155270770 5.04 ENST00000392414.3
pyruvate kinase, liver and RBC
chr3_-_126236588 4.95 ENST00000383579.3
urocanate hydratase 1
chr12_+_121416489 4.82 ENST00000541395.1
ENST00000544413.1
HNF1 homeobox A
chr3_+_100354442 4.63 ENST00000475887.1
G protein-coupled receptor 128
chr11_+_63057412 4.60 ENST00000544661.1
solute carrier family 22, member 10
chr12_-_56882136 4.56 ENST00000311966.4
glutaminase 2 (liver, mitochondrial)
chr1_-_155271213 4.53 ENST00000342741.4
pyruvate kinase, liver and RBC
chr1_+_145727681 4.40 ENST00000417171.1
ENST00000451928.2
PDZ domain containing 1
chr2_-_238499131 4.26 ENST00000538644.1
RAB17, member RAS oncogene family
chr20_+_42187682 4.20 ENST00000373092.3
ENST00000373077.1
serum/glucocorticoid regulated kinase 2
chr9_-_104145795 4.17 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr12_+_20963632 4.09 ENST00000540853.1
ENST00000261196.2
solute carrier organic anion transporter family, member 1B3
chr14_-_94854926 4.09 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_177939348 4.08 ENST00000464631.2
SEC16 homolog B (S. cerevisiae)
chrX_+_2746850 4.08 ENST00000381163.3
ENST00000338623.5
ENST00000542787.1
glycogenin 2
chr1_-_169555779 4.05 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr19_+_41594377 4.05 ENST00000330436.3
cytochrome P450, family 2, subfamily A, polypeptide 13
chr22_-_37415475 4.00 ENST00000403892.3
ENST00000249042.3
ENST00000438203.1
thiosulfate sulfurtransferase (rhodanese)
chr2_-_238499337 3.99 ENST00000411462.1
ENST00000409822.1
RAB17, member RAS oncogene family
chr19_-_19373601 3.98 ENST00000291481.7
hyaluronan and proteoglycan link protein 4
chr20_+_42187608 3.94 ENST00000373100.1
serum/glucocorticoid regulated kinase 2
chr19_-_6720686 3.90 ENST00000245907.6
complement component 3
chr12_+_20963647 3.89 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr2_-_238499303 3.88 ENST00000409576.1
RAB17, member RAS oncogene family
chr2_-_238499725 3.87 ENST00000264601.3
RAB17, member RAS oncogene family
chr1_-_211752073 3.87 ENST00000367001.4
solute carrier family 30 (zinc transporter), member 1
chr19_+_7660716 3.80 ENST00000160298.4
ENST00000446248.2
calmodulin regulated spectrin-associated protein family, member 3
chr2_+_242750321 3.79 ENST00000423583.1
sialidase 4
chrX_+_2746818 3.78 ENST00000398806.3
glycogenin 2
chr2_+_242750160 3.76 ENST00000415936.1
sialidase 4
chr1_-_201368707 3.72 ENST00000391967.2
ladinin 1
chr7_+_45927956 3.69 ENST00000275525.3
ENST00000457280.1
insulin-like growth factor binding protein 1
chr19_-_4535233 3.68 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr13_+_113812956 3.65 ENST00000375547.2
ENST00000342783.4
protein Z, vitamin K-dependent plasma glycoprotein
chr3_+_119501557 3.57 ENST00000337940.4
nuclear receptor subfamily 1, group I, member 2
chr11_-_66725837 3.57 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
pyruvate carboxylase
chr2_-_31637560 3.56 ENST00000379416.3
xanthine dehydrogenase
chr7_-_87104963 3.56 ENST00000359206.3
ENST00000358400.3
ENST00000265723.4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr11_+_74870818 3.55 ENST00000525845.1
ENST00000534186.1
ENST00000428359.2
solute carrier organic anion transporter family, member 2B1
chr14_+_103394963 3.39 ENST00000559525.1
ENST00000559789.1
amnion associated transmembrane protein
chr11_-_66496430 3.35 ENST00000533211.1
spectrin, beta, non-erythrocytic 2
chr9_-_136605042 3.33 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
sarcosine dehydrogenase
chr20_-_7921090 3.31 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr21_-_37852359 3.30 ENST00000399137.1
ENST00000399135.1
claudin 14
chr17_+_7531281 3.28 ENST00000575729.1
ENST00000340624.5
sex hormone-binding globulin
chr3_-_58200398 3.25 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
deoxyribonuclease I-like 3
chr4_-_171011084 3.22 ENST00000337664.4
aminoadipate aminotransferase
chr7_+_45928079 3.21 ENST00000468955.1
insulin-like growth factor binding protein 1
chr17_-_17740287 3.21 ENST00000355815.4
ENST00000261646.5
sterol regulatory element binding transcription factor 1
chr1_+_207262540 3.18 ENST00000452902.2
complement component 4 binding protein, beta
chr3_+_100328433 3.16 ENST00000273352.3
G protein-coupled receptor 128
chr1_-_201368653 3.13 ENST00000367313.3
ladinin 1
chr2_-_73869508 3.11 ENST00000272425.3
N-acetyltransferase 8 (GCN5-related, putative)
chr22_+_37415700 3.11 ENST00000397129.1
mercaptopyruvate sulfurtransferase
chr6_-_41006928 3.08 ENST00000244565.3
unc-5 homolog C (C. elegans)-like
chr16_+_56659687 3.04 ENST00000568293.1
ENST00000330439.6
metallothionein 1E
chr9_+_133320339 3.03 ENST00000372394.1
ENST00000372393.3
ENST00000422569.1
argininosuccinate synthase 1
chrX_+_46937745 3.02 ENST00000397180.1
ENST00000457380.1
ENST00000352078.4
regucalcin
chr17_-_17740325 2.98 ENST00000338854.5
sterol regulatory element binding transcription factor 1
chr6_+_30130969 2.98 ENST00000376694.4
tripartite motif containing 15
chr13_-_44980021 2.95 ENST00000432701.2
ENST00000607312.1
long intergenic non-protein coding RNA 1071
chr2_-_43019698 2.94 ENST00000431905.1
ENST00000294973.6
3-hydroxyanthranilate 3,4-dioxygenase
chr12_+_121163538 2.90 ENST00000242592.4
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr19_-_58864848 2.90 ENST00000263100.3
alpha-1-B glycoprotein
chr16_+_29690358 2.87 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr11_-_2158507 2.86 ENST00000381392.1
ENST00000381395.1
ENST00000418738.2
insulin-like growth factor 2 (somatomedin A)
chr19_-_39303576 2.85 ENST00000594209.1
lectin, galactoside-binding, soluble, 4
chr1_-_169555709 2.85 ENST00000546081.1
coagulation factor V (proaccelerin, labile factor)
chr14_+_105046021 2.84 ENST00000557649.1
chromosome 14 open reading frame 180
chr6_+_31620191 2.80 ENST00000375918.2
ENST00000375920.4
apolipoprotein M
chr17_-_36105009 2.75 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1 homeobox B
chr13_+_113777105 2.74 ENST00000409306.1
ENST00000375551.3
ENST00000375559.3
coagulation factor X
chr14_+_105046094 2.73 ENST00000331952.2
chromosome 14 open reading frame 180
chr1_+_207262170 2.72 ENST00000367078.3
complement component 4 binding protein, beta
chr22_-_37505588 2.70 ENST00000406856.1
transmembrane protease, serine 6
chrX_+_128872998 2.67 ENST00000371106.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr22_-_37505449 2.66 ENST00000406725.1
transmembrane protease, serine 6
chr12_+_56477093 2.65 ENST00000549672.1
ENST00000415288.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr20_-_7238861 2.64 ENST00000428954.1
RP11-19D2.1
chr11_+_18417813 2.63 ENST00000540430.1
ENST00000379412.5
lactate dehydrogenase A
chr16_-_87970122 2.62 ENST00000309893.2
carbonic anhydrase VA, mitochondrial
chr2_+_44502630 2.60 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr1_-_204116078 2.58 ENST00000367198.2
ENST00000452983.1
ethanolamine kinase 2
chr19_-_3480540 2.56 ENST00000215531.4
chromosome 19 open reading frame 77
chr22_+_37415776 2.56 ENST00000341116.3
ENST00000429360.2
ENST00000404393.1
mercaptopyruvate sulfurtransferase
chrX_+_128872918 2.54 ENST00000371105.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr11_+_63137251 2.49 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr10_-_69597915 2.49 ENST00000225171.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr14_+_70346125 2.46 ENST00000361956.3
ENST00000381280.4
SPARC related modular calcium binding 1
chr4_-_1188922 2.45 ENST00000515004.1
ENST00000502483.1
spondin 2, extracellular matrix protein
chrX_-_15288154 2.40 ENST00000380483.3
ENST00000380485.3
ENST00000380488.4
ankyrin repeat and SOCS box containing 9
chr12_+_121416340 2.40 ENST00000257555.6
ENST00000400024.2
HNF1 homeobox A
chr22_+_37415676 2.38 ENST00000401419.3
mercaptopyruvate sulfurtransferase
chr5_-_36242119 2.37 ENST00000511088.1
ENST00000282512.3
ENST00000506945.1
NAD kinase 2, mitochondrial
chr7_-_1595107 2.35 ENST00000414730.1
transmembrane protein 184A
chr8_+_27348626 2.33 ENST00000517536.1
epoxide hydrolase 2, cytoplasmic
chr22_+_37415728 2.32 ENST00000404802.3
mercaptopyruvate sulfurtransferase
chr16_+_19179549 2.31 ENST00000355377.2
ENST00000568115.1
synaptotagmin XVII
chr10_-_69597810 2.31 ENST00000483798.2
DnaJ (Hsp40) homolog, subfamily C, member 12
chr8_+_27348649 2.31 ENST00000521780.1
ENST00000380476.3
ENST00000518379.1
ENST00000521684.1
epoxide hydrolase 2, cytoplasmic
chr11_+_18417948 2.29 ENST00000542179.1
lactate dehydrogenase A
chr1_-_24126892 2.27 ENST00000374497.3
ENST00000425913.1
UDP-galactose-4-epimerase
chr10_+_88854926 2.26 ENST00000298784.1
ENST00000298786.4
family with sequence similarity 35, member A
chr2_-_27341966 2.24 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
cell growth regulator with EF-hand domain 1
chr16_+_27226256 2.24 ENST00000567735.1
lysine (K)-specific demethylase 8
chr4_-_171011323 2.22 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
aminoadipate aminotransferase
chr15_-_89010607 2.21 ENST00000312475.4
mitochondrial ribosomal protein L46
chr2_+_217524323 2.19 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr1_+_155099927 2.18 ENST00000368407.3
ephrin-A1
chr8_+_11561660 2.15 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA binding protein 4
chr5_-_156390230 2.12 ENST00000407087.3
ENST00000274532.2
T-cell immunoglobulin and mucin domain containing 4
chrX_-_99891796 2.10 ENST00000373020.4
tetraspanin 6
chr21_-_44898015 2.09 ENST00000332440.3
long intergenic non-protein coding RNA 313
chr12_+_121416437 2.09 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1 homeobox A
chr2_+_242498135 2.05 ENST00000318407.3
BCL2-related ovarian killer
chr11_-_66496655 2.02 ENST00000527010.1
spectrin, beta, non-erythrocytic 2
chr16_+_56642041 2.02 ENST00000245185.5
metallothionein 2A
chr21_+_17553910 2.01 ENST00000428669.2
long intergenic non-protein coding RNA 478
chr18_-_712544 2.00 ENST00000340116.7
ENST00000539164.1
ENST00000580982.1
enolase superfamily member 1
chr3_+_153839149 1.95 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr12_+_121163602 1.94 ENST00000411593.2
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr16_+_83932684 1.93 ENST00000262430.4
malonyl-CoA decarboxylase
chr1_-_209824643 1.88 ENST00000391911.1
ENST00000415782.1
laminin, beta 3
chr10_-_69597828 1.87 ENST00000339758.7
DnaJ (Hsp40) homolog, subfamily C, member 12
chr3_+_154801678 1.87 ENST00000462837.1
membrane metallo-endopeptidase
chr1_+_94883991 1.86 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr17_-_17494972 1.86 ENST00000435340.2
ENST00000255389.5
ENST00000395781.2
phosphatidylethanolamine N-methyltransferase
chr19_-_30199516 1.85 ENST00000591243.1
chromosome 19 open reading frame 12
chr11_-_57177586 1.82 ENST00000529411.1
Uncharacterized protein
chrX_-_43741594 1.81 ENST00000536181.1
ENST00000378069.4
monoamine oxidase B
chr17_-_1553346 1.80 ENST00000301336.6
Rab interacting lysosomal protein
chrX_+_66764375 1.80 ENST00000374690.3
androgen receptor
chr1_-_67519782 1.79 ENST00000235345.5
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr12_-_322504 1.77 ENST00000424061.2
solute carrier family 6 (neurotransmitter transporter), member 12
chr20_+_61584026 1.76 ENST00000370351.4
ENST00000370349.3
solute carrier family 17 (vesicular nucleotide transporter), member 9
chr3_-_48471454 1.74 ENST00000296440.6
ENST00000448774.2
plexin B1
chr6_-_39902160 1.73 ENST00000340692.5
molybdenum cofactor synthesis 1
chr14_+_24458021 1.69 ENST00000397071.1
ENST00000559411.1
ENST00000335125.6
dehydrogenase/reductase (SDR family) member 4 like 2
chr1_-_153581798 1.69 ENST00000368704.1
ENST00000368705.2
S100 calcium binding protein A16
chr5_+_179125907 1.67 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
calnexin
chr1_+_94883931 1.67 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ATP-binding cassette, sub-family D (ALD), member 3
chr5_-_43313574 1.67 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr19_+_6464243 1.65 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr20_+_13202418 1.65 ENST00000262487.4
isthmin 1, angiogenesis inhibitor
chr14_+_24458123 1.63 ENST00000545240.1
ENST00000382755.4
dehydrogenase/reductase (SDR family) member 4 like 2
chr20_-_36794902 1.60 ENST00000373403.3
transglutaminase 2
chr8_-_27469196 1.59 ENST00000546343.1
ENST00000560566.1
clusterin
chr11_-_74442430 1.58 ENST00000376332.3
chordin-like 2
chr20_-_32308028 1.57 ENST00000409299.3
ENST00000217398.3
ENST00000344022.3
peroxisomal membrane protein 4, 24kDa
chr19_-_34012674 1.57 ENST00000436370.3
ENST00000397032.4
ENST00000244137.7
peptidase D
chr12_+_112204691 1.57 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr1_+_246887349 1.56 ENST00000366510.3
saccharopine dehydrogenase (putative)
chr14_+_77790901 1.53 ENST00000553586.1
ENST00000555583.1
glutathione S-transferase zeta 1
chr14_-_23446021 1.53 ENST00000553592.1
ajuba LIM protein
chr8_-_120259055 1.52 ENST00000522828.1
ENST00000523307.1
ENST00000524129.1
ENST00000521048.1
ENST00000522187.1
RP11-4K16.2
chr5_+_148521381 1.51 ENST00000504238.1
actin binding LIM protein family, member 3
chr2_+_11682790 1.50 ENST00000389825.3
ENST00000381483.2
growth regulation by estrogen in breast cancer 1
chr1_-_230513367 1.50 ENST00000321327.2
ENST00000525115.1
piggyBac transposable element derived 5
chr16_+_56995854 1.50 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr10_+_89419370 1.50 ENST00000361175.4
ENST00000456849.1
3'-phosphoadenosine 5'-phosphosulfate synthase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HNF4G

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.0 23.9 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
4.2 12.5 GO:0060621 negative regulation of cholesterol import(GO:0060621) negative regulation of sterol import(GO:2000910)
4.1 12.2 GO:0090675 intermicrovillar adhesion(GO:0090675)
3.6 10.9 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
3.2 16.2 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
3.2 16.0 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
3.1 9.3 GO:0035623 renal glucose absorption(GO:0035623)
3.1 15.4 GO:0006524 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
3.0 24.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
2.9 14.4 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
2.7 2.7 GO:0035565 regulation of pronephros size(GO:0035565)
2.1 6.3 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
2.0 9.8 GO:0009698 phenylpropanoid metabolic process(GO:0009698)
1.8 12.5 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
1.7 10.3 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.4 10.0 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
1.4 6.9 GO:0032571 response to vitamin K(GO:0032571)
1.4 31.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
1.3 3.9 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
1.3 3.9 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
1.2 4.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.2 3.7 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
1.2 5.9 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
1.2 3.6 GO:1901656 cellular response to mycotoxin(GO:0036146) glycoside transport(GO:1901656) cellular response to bile acid(GO:1903413)
1.2 2.4 GO:0001794 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
1.2 11.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
1.1 3.4 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.1 3.3 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
1.1 9.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.1 12.7 GO:0006689 ganglioside catabolic process(GO:0006689)
0.9 3.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.9 3.6 GO:0046110 xanthine metabolic process(GO:0046110)
0.8 5.9 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.7 4.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 5.8 GO:0046874 quinolinate metabolic process(GO:0046874)
0.6 5.2 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 3.1 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.6 1.8 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.6 1.8 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.6 11.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.6 2.8 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.6 3.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.5 2.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.5 2.0 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.5 3.6 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.5 1.5 GO:0060061 Spemann organizer formation(GO:0060061)
0.5 8.1 GO:0015747 urate transport(GO:0015747)
0.5 9.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.4 1.8 GO:1905225 response to thyrotropin-releasing hormone(GO:1905225)
0.4 3.3 GO:0015811 L-cystine transport(GO:0015811)
0.4 16.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.4 5.9 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.4 6.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.4 1.9 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.4 1.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.4 1.5 GO:0000103 sulfate assimilation(GO:0000103)
0.4 0.7 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.4 0.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 2.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.4 6.9 GO:0071280 cellular response to copper ion(GO:0071280)
0.4 1.1 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.3 1.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.3 4.2 GO:0019530 taurine metabolic process(GO:0019530)
0.3 3.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.3 1.3 GO:1904106 protein localization to microvillus(GO:1904106)
0.3 1.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.3 3.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.3 0.9 GO:1902908 regulation of melanosome transport(GO:1902908)
0.3 2.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.3 9.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 1.7 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 2.3 GO:0046449 creatinine metabolic process(GO:0046449)
0.3 5.4 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3 0.8 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 0.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.3 2.9 GO:2000467 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 1.0 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 5.4 GO:0097264 self proteolysis(GO:0097264)
0.2 1.2 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.7 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 3.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.9 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 0.9 GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.2 1.8 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 1.7 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.2 1.4 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 1.0 GO:0043335 protein unfolding(GO:0043335)
0.2 1.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 14.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.2 3.8 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.3 GO:1902896 terminal web assembly(GO:1902896)
0.2 0.5 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2 1.8 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.9 GO:0000050 urea cycle(GO:0000050)
0.2 2.3 GO:0019388 galactose catabolic process(GO:0019388)
0.2 1.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 3.0 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.2 1.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.2 0.2 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956) negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.2 1.6 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.2 2.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 1.9 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.2 13.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 1.7 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 1.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 15.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 1.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 10.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.3 GO:0006568 tryptophan metabolic process(GO:0006568)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 2.7 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.6 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 1.5 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 1.2 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 0.8 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.7 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 1.7 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 2.5 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.1 7.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.1 0.5 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 4.4 GO:0015879 carnitine transport(GO:0015879)
0.1 0.4 GO:0071262 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.6 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.5 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 1.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.9 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 2.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.9 GO:0061368 negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.5 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 1.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.7 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.7 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 3.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 1.3 GO:0016198 axon choice point recognition(GO:0016198)
0.1 3.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 1.0 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.0 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 1.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 1.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 6.1 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.5 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 2.6 GO:0001502 cartilage condensation(GO:0001502)
0.1 1.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.1 0.9 GO:0044597 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 2.0 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.6 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.4 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 1.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 1.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 6.6 GO:0006901 vesicle coating(GO:0006901)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.5 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 1.9 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 1.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 2.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0045914 cellular response to phosphate starvation(GO:0016036) positive regulation of sulfur amino acid metabolic process(GO:0031337) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.5 GO:0032467 positive regulation of cytokinesis(GO:0032467) mitotic spindle midzone assembly(GO:0051256)
0.0 2.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 2.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 5.8 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 3.1 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 1.3 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.6 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.0 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.7 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 2.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.6 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.6 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.8 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 1.8 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 2.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.6 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.8 GO:0003148 outflow tract septum morphogenesis(GO:0003148)
0.0 0.4 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.3 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.7 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 1.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.4 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 2.9 GO:0044275 cellular carbohydrate catabolic process(GO:0044275)
0.0 0.6 GO:0015695 organic cation transport(GO:0015695)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.0 0.7 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:1904141 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0 1.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 2.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.5 GO:0044030 regulation of DNA methylation(GO:0044030)
0.0 0.1 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0010813 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.4 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.9 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.0 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 1.3 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.0 0.5 GO:0031297 replication fork processing(GO:0031297)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 28.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.8 2.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
2.4 12.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.1 11.5 GO:0005579 membrane attack complex(GO:0005579)
0.6 10.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.6 1.7 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.5 7.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.5 35.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.4 5.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.4 8.1 GO:0042627 chylomicron(GO:0042627)
0.3 3.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.3 1.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.3 5.4 GO:0008091 spectrin(GO:0008091)
0.2 0.6 GO:0034515 proteasome storage granule(GO:0034515)
0.2 19.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.2 21.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 0.7 GO:0031905 early endosome lumen(GO:0031905)
0.2 1.9 GO:0005610 laminin-5 complex(GO:0005610)
0.2 1.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 26.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 2.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 14.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 19.5 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.7 GO:0005602 complement component C1 complex(GO:0005602)
0.1 3.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 12.8 GO:0031526 brush border membrane(GO:0031526)
0.1 3.4 GO:0005915 zonula adherens(GO:0005915)
0.1 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 4.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.9 GO:0042382 paraspeckles(GO:0042382)
0.1 7.0 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.3 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 9.4 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.0 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.3 GO:0032433 filopodium tip(GO:0032433)
0.1 0.8 GO:0033010 paranodal junction(GO:0033010)
0.1 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.9 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 5.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0005869 dynactin complex(GO:0005869)
0.0 3.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 7.3 GO:0005604 basement membrane(GO:0005604)
0.0 20.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 33.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.8 GO:0005903 brush border(GO:0005903)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 5.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 0.4 GO:0032153 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 12.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 43.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 5.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 3.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 4.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 8.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.6 GO:0031932 TORC2 complex(GO:0031932)
0.0 4.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.5 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.0 7.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 3.4 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.5 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.6 10.4 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
2.6 10.3 GO:0004998 transferrin receptor activity(GO:0004998)
2.4 54.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
2.3 16.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
2.0 4.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
1.8 5.4 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
1.6 9.6 GO:0004743 pyruvate kinase activity(GO:0004743)
1.6 12.7 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
1.6 7.9 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
1.4 8.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
1.3 9.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
1.3 11.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.1 3.3 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
1.1 3.3 GO:0052853 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.9 5.6 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.8 6.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.7 4.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.7 6.2 GO:0032810 sterol response element binding(GO:0032810)
0.6 9.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.6 1.9 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.6 5.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.6 3.7 GO:0035473 lipase binding(GO:0035473)
0.6 1.8 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.6 2.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.6 4.6 GO:0004359 glutaminase activity(GO:0004359)
0.6 2.3 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.6 1.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.6 4.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.5 1.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.5 5.1 GO:0005497 androgen binding(GO:0005497)
0.5 1.5 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.5 24.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5 12.3 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 2.4 GO:0019770 IgG receptor activity(GO:0019770)
0.5 2.3 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.4 7.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 11.5 GO:0019841 retinol binding(GO:0019841)
0.4 14.7 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.4 3.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.4 2.8 GO:0016936 galactoside binding(GO:0016936)
0.4 1.2 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.4 3.6 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.4 3.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 1.5 GO:0017129 triglyceride binding(GO:0017129)
0.4 3.7 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.4 2.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.4 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.4 1.1 GO:0015235 cobalamin transporter activity(GO:0015235)
0.3 0.9 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.3 3.6 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.3 0.9 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.3 1.4 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.3 7.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 1.8 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 8.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.2 3.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 0.7 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.2 2.6 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.2 0.7 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 0.7 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 0.7 GO:0036317 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.2 1.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 3.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 0.2 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2 0.6 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 3.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 2.7 GO:0038132 neuregulin binding(GO:0038132)
0.2 5.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 1.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 14.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 0.7 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 1.5 GO:0017040 ceramidase activity(GO:0017040)
0.2 2.2 GO:0051525 NFAT protein binding(GO:0051525)
0.2 0.5 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 5.2 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.4 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 1.9 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.4 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 3.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 14.3 GO:0019003 GDP binding(GO:0019003)
0.1 2.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.9 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 10.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 2.0 GO:0046870 cadmium ion binding(GO:0046870)
0.1 1.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 1.5 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.8 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.6 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.5 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 2.9 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.3 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 0.9 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 2.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.1 1.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 2.0 GO:0051400 BH domain binding(GO:0051400)
0.1 4.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 2.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 13.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 32.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.8 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.0 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.9 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.9 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 9.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 1.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 3.7 GO:0030546 receptor activator activity(GO:0030546)
0.1 2.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.6 GO:0019534 toxin transporter activity(GO:0019534)
0.1 2.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.5 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 1.0 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 1.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 2.9 GO:0005507 copper ion binding(GO:0005507)
0.0 1.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 4.9 GO:0016597 amino acid binding(GO:0016597)
0.0 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.2 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 3.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0030507 spectrin binding(GO:0030507)
0.0 1.4 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.8 GO:0001618 virus receptor activity(GO:0001618)
0.0 8.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.1 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 32.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 29.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 3.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 6.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 1.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 42.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 6.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 3.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 3.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 4.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.7 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 8.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 4.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 54.4 REACTOME XENOBIOTICS Genes involved in Xenobiotics
1.5 27.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
1.1 32.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.8 11.0 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.6 10.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 6.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.5 6.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.5 28.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.5 20.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.4 11.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 8.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 7.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 4.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.2 3.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 6.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 13.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.2 3.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 53.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.2 2.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 1.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 6.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 6.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 2.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 4.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.9 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 11.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 4.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 5.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 2.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 2.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 2.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.7 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 5.2 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 7.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 2.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 2.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.8 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport