Project

Illumina Body Map 2

Navigation
Downloads

Results for HOXA2_HOXB1

Z-value: 1.56

Motif logo

Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
ENSG00000105996.5 homeobox A2
ENSG00000120094.6 homeobox B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB1hg19_v2_chr17_-_46608272_466083850.251.6e-01Click!
HOXA2hg19_v2_chr7_-_27142290_271424300.077.1e-01Click!

Activity profile of HOXA2_HOXB1 motif

Sorted Z-values of HOXA2_HOXB1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_93616340 14.32 ENST00000557420.1
ENST00000542321.2
repulsive guidance molecule family member a
chr12_+_101988627 14.01 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
myosin binding protein C, slow type
chr12_+_101988774 13.32 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
myosin binding protein C, slow type
chr15_-_93616892 10.41 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
repulsive guidance molecule family member a
chr16_-_49890016 8.37 ENST00000563137.2
zinc finger protein 423
chr17_-_37353950 7.28 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
calcium channel, voltage-dependent, beta 1 subunit
chr6_+_151561085 6.42 ENST00000402676.2
A kinase (PRKA) anchor protein 12
chr2_-_154335300 6.06 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr11_-_111782696 5.65 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr6_+_151561506 5.64 ENST00000253332.1
A kinase (PRKA) anchor protein 12
chr11_-_111782484 5.39 ENST00000533971.1
crystallin, alpha B
chr12_-_15038779 4.99 ENST00000228938.5
ENST00000539261.1
matrix Gla protein
chr18_+_56887381 4.55 ENST00000256857.2
ENST00000529320.2
ENST00000420468.2
gastrin-releasing peptide
chr20_+_34802295 4.25 ENST00000432603.1
erythrocyte membrane protein band 4.1-like 1
chr17_+_37824411 4.25 ENST00000269582.2
phenylethanolamine N-methyltransferase
chr16_-_79263322 4.14 ENST00000569677.1
RP11-679B19.2
chr7_-_27170352 3.94 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr17_+_37824217 3.94 ENST00000394246.1
phenylethanolamine N-methyltransferase
chr5_+_98109322 3.92 ENST00000513185.1
repulsive guidance molecule family member b
chr11_-_2162162 3.90 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr3_+_189507523 3.66 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
tumor protein p63
chr17_+_39975544 3.65 ENST00000544340.1
FK506 binding protein 10, 65 kDa
chr16_+_7560114 3.61 ENST00000570626.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr17_+_39975455 3.59 ENST00000455106.1
FK506 binding protein 10, 65 kDa
chr3_-_187388173 3.49 ENST00000287641.3
somatostatin
chr17_+_37824700 3.49 ENST00000581428.1
phenylethanolamine N-methyltransferase
chrX_-_13835398 3.33 ENST00000475307.1
glycoprotein M6B
chr14_-_54425475 3.32 ENST00000559642.1
bone morphogenetic protein 4
chrX_-_13835147 2.99 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr16_+_15596123 2.98 ENST00000452191.2
chromosome 16 open reading frame 45
chr19_-_49944806 2.97 ENST00000221485.3
solute carrier family 17 (vesicular glutamate transporter), member 7
chrX_-_13835461 2.94 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr2_-_45236540 2.79 ENST00000303077.6
SIX homeobox 2
chr16_+_66429358 2.78 ENST00000539168.1
cadherin 5, type 2 (vascular endothelium)
chr3_+_189507432 2.77 ENST00000354600.5
tumor protein p63
chr10_+_24755416 2.71 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr5_-_125930877 2.70 ENST00000510111.2
ENST00000509270.1
aldehyde dehydrogenase 7 family, member A1
chr11_-_126870683 2.64 ENST00000525704.2
kin of IRRE like 3 (Drosophila)
chr2_+_176995011 2.63 ENST00000548663.1
ENST00000450510.2
homeobox D8
chr6_-_112575687 2.60 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
laminin, alpha 4
chr14_-_21516590 2.50 ENST00000555026.1
NDRG family member 2
chr6_-_112575912 2.36 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
laminin, alpha 4
chr2_+_36923901 2.31 ENST00000457137.2
vitrin
chrX_-_10645773 2.29 ENST00000453318.2
midline 1 (Opitz/BBB syndrome)
chr7_-_86595190 2.27 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324-like
chr3_+_112929850 2.26 ENST00000464546.1
BOC cell adhesion associated, oncogene regulated
chr3_+_159481988 2.24 ENST00000472451.1
IQCJ-SCHIP1 readthrough
chr6_+_155334780 2.21 ENST00000538270.1
ENST00000535231.1
T-cell lymphoma invasion and metastasis 2
chr4_-_5021164 2.19 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
cytokine-like 1
chr7_-_25790603 2.16 ENST00000456777.1
AC003090.1
chrX_+_99899180 2.16 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr10_-_100995540 2.15 ENST00000370546.1
ENST00000404542.1
heparanase 2
chr6_-_112575758 2.13 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
laminin, alpha 4
chr5_-_125930929 2.12 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr10_-_79397202 1.98 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_25703274 1.98 ENST00000331351.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr12_-_28124903 1.89 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr2_-_23747214 1.88 ENST00000430988.1
Uncharacterized protein
chr2_+_36923933 1.86 ENST00000497382.1
ENST00000404084.1
ENST00000379241.3
ENST00000401530.1
vitrin
chr20_+_34742650 1.86 ENST00000373945.1
ENST00000338074.2
erythrocyte membrane protein band 4.1-like 1
chr21_+_19617140 1.86 ENST00000299295.2
ENST00000338326.3
chondrolectin
chr10_-_79397316 1.83 ENST00000372421.5
ENST00000457953.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr3_+_148545586 1.80 ENST00000282957.4
ENST00000468341.1
carboxypeptidase B1 (tissue)
chr10_-_105615164 1.80 ENST00000355946.2
ENST00000369774.4
SH3 and PX domains 2A
chr2_+_36923830 1.76 ENST00000379242.3
ENST00000389975.3
vitrin
chr11_-_93583697 1.72 ENST00000409977.1
V-set and transmembrane domain containing 5
chr10_+_95848824 1.72 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr7_+_79765071 1.63 ENST00000457358.2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr13_-_36050819 1.61 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr10_+_124320156 1.61 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
deleted in malignant brain tumors 1
chr3_-_46786245 1.55 ENST00000442359.2
protease, serine, 45
chr10_-_100995603 1.53 ENST00000370552.3
ENST00000370549.1
heparanase 2
chr20_+_52105495 1.50 ENST00000439873.2
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr7_-_150864635 1.49 ENST00000297537.4
gastrulation brain homeobox 1
chr10_-_79397547 1.48 ENST00000481070.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr17_+_48609903 1.42 ENST00000268933.3
epsin 3
chr7_+_26591441 1.42 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2
chr12_-_49393092 1.40 ENST00000421952.2
dendrin
chr17_+_36584662 1.40 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr9_+_124329336 1.38 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr7_+_20370746 1.36 ENST00000222573.4
integrin, beta 8
chr10_-_79397479 1.27 ENST00000404771.3
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr9_+_113431029 1.25 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
muscle, skeletal, receptor tyrosine kinase
chr3_+_189507460 1.24 ENST00000434928.1
tumor protein p63
chr7_+_86273218 1.23 ENST00000361669.2
glutamate receptor, metabotropic 3
chr10_-_98945264 1.23 ENST00000314867.5
slit homolog 1 (Drosophila)
chr7_-_14029515 1.22 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ets variant 1
chr6_+_73331520 1.22 ENST00000342056.2
ENST00000355194.4
potassium voltage-gated channel, KQT-like subfamily, member 5
chr15_-_74501310 1.21 ENST00000423167.2
ENST00000432245.2
stimulated by retinoic acid 6
chr16_-_67427389 1.20 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr1_-_217250231 1.14 ENST00000493748.1
ENST00000463665.1
estrogen-related receptor gamma
chr1_+_178062855 1.12 ENST00000448150.3
RAS protein activator like 2
chr8_-_38008783 1.11 ENST00000276449.4
steroidogenic acute regulatory protein
chr6_-_112575838 1.11 ENST00000455073.1
laminin, alpha 4
chr11_-_126870655 1.10 ENST00000525144.2
kin of IRRE like 3 (Drosophila)
chr3_+_150264555 1.08 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
eukaryotic translation initiation factor 2A, 65kDa
chr10_+_18689637 1.07 ENST00000377315.4
calcium channel, voltage-dependent, beta 2 subunit
chr17_-_57604200 1.07 ENST00000577478.1
RP11-567L7.6
chr8_+_143530791 1.06 ENST00000517894.1
brain-specific angiogenesis inhibitor 1
chr15_+_48009541 1.05 ENST00000536845.2
ENST00000558816.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_+_46706725 1.04 ENST00000434431.1
transmembrane protein 247
chr10_+_124320195 0.99 ENST00000359586.6
deleted in malignant brain tumors 1
chr12_-_114843889 0.99 ENST00000405440.2
T-box 5
chr3_+_150264458 0.99 ENST00000487799.1
ENST00000460851.1
eukaryotic translation initiation factor 2A, 65kDa
chr12_+_7023491 0.98 ENST00000541477.1
ENST00000229277.1
enolase 2 (gamma, neuronal)
chrX_+_125953746 0.94 ENST00000371125.3
chromosome X open reading frame 64
chr1_-_67390474 0.92 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WD repeat domain 78
chrX_-_10645724 0.91 ENST00000413894.1
midline 1 (Opitz/BBB syndrome)
chr7_-_120497178 0.90 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
tetraspanin 12
chr1_-_182642017 0.90 ENST00000367557.4
ENST00000258302.4
regulator of G-protein signaling 8
chr3_+_239652 0.86 ENST00000435603.1
cell adhesion molecule L1-like
chr4_-_90757364 0.83 ENST00000508895.1
synuclein, alpha (non A4 component of amyloid precursor)
chr8_-_67874805 0.82 ENST00000563496.1
transcription factor 24
chr2_-_190044480 0.80 ENST00000374866.3
collagen, type V, alpha 2
chr9_-_101471479 0.78 ENST00000259455.2
gamma-aminobutyric acid (GABA) B receptor, 2
chr11_+_133902667 0.77 ENST00000533091.1
ENST00000527712.1
RP11-713P17.3
chr9_+_113431059 0.77 ENST00000416899.2
muscle, skeletal, receptor tyrosine kinase
chr1_-_205391178 0.75 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEM domain containing 1
chr2_+_26624775 0.75 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr2_-_142888573 0.75 ENST00000434794.1
low density lipoprotein receptor-related protein 1B
chrX_+_82763265 0.75 ENST00000373200.2
POU class 3 homeobox 4
chr18_+_18943554 0.74 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr6_+_29426230 0.73 ENST00000442615.1
olfactory receptor, family 2, subfamily H, member 1
chr6_+_32006042 0.72 ENST00000418967.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr2_+_242089833 0.71 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
protein phosphatase 1, regulatory subunit 7
chr4_-_113437328 0.65 ENST00000313341.3
neurogenin 2
chr4_-_90756769 0.64 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
synuclein, alpha (non A4 component of amyloid precursor)
chr14_-_81893734 0.62 ENST00000555447.1
stonin 2
chr16_+_30080857 0.61 ENST00000565355.1
aldolase A, fructose-bisphosphate
chr1_-_65533390 0.61 ENST00000448344.1
RP4-535B20.1
chr2_+_166326157 0.61 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
cysteine-serine-rich nuclear protein 3
chr15_-_95870348 0.59 ENST00000556899.1
CTD-2536I1.1
chr13_+_36050881 0.58 ENST00000537702.1
neurobeachin
chr19_+_37997812 0.58 ENST00000542455.1
ENST00000587143.1
zinc finger protein 793
chr15_-_74501360 0.57 ENST00000323940.5
stimulated by retinoic acid 6
chr12_-_86650045 0.56 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_28125638 0.55 ENST00000545234.1
parathyroid hormone-like hormone
chr8_-_22550691 0.51 ENST00000519492.1
early growth response 3
chr9_-_73477826 0.49 ENST00000396285.1
ENST00000396292.4
ENST00000396280.5
ENST00000358082.3
ENST00000408909.2
ENST00000377097.3
transient receptor potential cation channel, subfamily M, member 3
chr6_+_32006159 0.49 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr8_+_77316233 0.48 ENST00000603284.1
ENST00000603837.1
RP11-706J10.2
long intergenic non-protein coding RNA 1109
chr19_+_35849723 0.47 ENST00000594310.1
free fatty acid receptor 3
chr1_-_109584716 0.47 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WD repeat domain 47
chr1_-_109584768 0.44 ENST00000357672.3
WD repeat domain 47
chr12_-_86650154 0.43 ENST00000552435.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_-_200323414 0.40 ENST00000443023.1
SATB homeobox 2
chr14_-_24733444 0.39 ENST00000560478.1
ENST00000560443.1
transglutaminase 1
chr8_-_143961236 0.39 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
cytochrome P450, family 11, subfamily B, polypeptide 1
chr2_+_121493717 0.39 ENST00000418323.1
GLI family zinc finger 2
chr9_+_40028620 0.39 ENST00000426179.1
AL353791.1
chr12_-_88423164 0.38 ENST00000298699.2
ENST00000550553.1
chromosome 12 open reading frame 50
chr7_-_144107320 0.37 ENST00000483238.1
ENST00000467773.1
NOBOX oogenesis homeobox
chr11_-_55905194 0.36 ENST00000301529.1
olfactory receptor, family 8, subfamily J, member 3
chr8_+_77596014 0.36 ENST00000523885.1
zinc finger homeobox 4
chr1_+_68150744 0.35 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chrX_-_65253506 0.34 ENST00000427538.1
V-set and immunoglobulin domain containing 4
chr7_-_100881041 0.32 ENST00000412417.1
ENST00000414035.1
claudin 15
chr11_+_47430133 0.32 ENST00000531974.1
ENST00000531419.1
ENST00000531865.1
ENST00000362021.4
ENST00000354884.4
solute carrier family 39 (zinc transporter), member 13
chr1_-_109584608 0.30 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WD repeat domain 47
chr20_+_30467600 0.30 ENST00000375934.4
ENST00000375922.4
tubulin tyrosine ligase-like family, member 9
chr1_+_243419306 0.29 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
serologically defined colon cancer antigen 8
chr12_+_10658489 0.29 ENST00000538173.1
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chrX_+_95939711 0.28 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr7_-_14029283 0.26 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr18_-_53070913 0.26 ENST00000568186.1
ENST00000564228.1
transcription factor 4
chr9_-_73029540 0.26 ENST00000377126.2
Kruppel-like factor 9
chr7_-_78400364 0.26 ENST00000535697.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr4_-_102267953 0.24 ENST00000523694.2
ENST00000507176.1
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_-_127269661 0.24 ENST00000373588.4
nuclear receptor subfamily 5, group A, member 1
chr3_-_98619999 0.23 ENST00000449482.1
discoidin, CUB and LCCL domain containing 2
chr17_+_43239231 0.21 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
hexamethylene bis-acetamide inducible 2
chr5_+_145826867 0.21 ENST00000296702.5
ENST00000394421.2
transcription elongation regulator 1
chr12_+_7022909 0.19 ENST00000537688.1
enolase 2 (gamma, neuronal)
chr15_-_95870310 0.18 ENST00000508732.2
CTD-2536I1.1
chr2_-_49381646 0.17 ENST00000346173.3
ENST00000406846.2
follicle stimulating hormone receptor
chr5_-_145895753 0.17 ENST00000311104.2
G protein-coupled receptor 151
chr17_+_7758374 0.17 ENST00000301599.6
ENST00000574668.1
transmembrane protein 88
chr8_-_143999259 0.17 ENST00000323110.2
cytochrome P450, family 11, subfamily B, polypeptide 2
chrX_+_95939638 0.17 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr12_+_57482877 0.16 ENST00000342556.6
ENST00000357680.4
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_-_44588694 0.16 ENST00000409957.1
prolyl endopeptidase-like
chr12_-_86650077 0.16 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_+_191046810 0.16 ENST00000392455.3
ENST00000392456.3
coiled-coil domain containing 50
chr2_-_200322723 0.15 ENST00000417098.1
SATB homeobox 2
chr2_-_44588679 0.12 ENST00000409411.1
prolyl endopeptidase-like
chr2_-_49381572 0.11 ENST00000454032.1
ENST00000304421.4
follicle stimulating hormone receptor
chr17_+_43239191 0.10 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chrY_+_26997726 0.09 ENST00000382296.2
deleted in azoospermia 4
chr19_+_44645731 0.07 ENST00000426739.2
zinc finger protein 234
chr1_-_43833628 0.06 ENST00000413844.2
ENST00000372458.3
ELOVL fatty acid elongase 1
chr7_-_78400598 0.05 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_+_125562370 0.05 ENST00000277309.2
olfactory receptor, family 1, subfamily K, member 1
chr19_+_47421933 0.04 ENST00000404338.3
Rho GTPase activating protein 35
chr16_-_54972581 0.03 ENST00000559802.1
ENST00000558156.1
CTD-3032H12.1
chr5_+_154181816 0.03 ENST00000518677.1
La ribonucleoprotein domain family, member 1
chr17_+_58755184 0.02 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
breast carcinoma amplified sequence 3
chr1_+_36621174 0.01 ENST00000429533.2
MAP7 domain containing 1
chr9_-_26947220 0.01 ENST00000520884.1
phospholipase A2-activating protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 11.7 GO:0042418 epinephrine biosynthetic process(GO:0042418)
1.9 7.7 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
1.8 7.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
1.2 3.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
1.2 27.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.2 4.8 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.0 3.0 GO:0042137 sequestering of neurotransmitter(GO:0042137)
1.0 24.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
1.0 10.7 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.9 4.6 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.8 12.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 3.0 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.7 3.5 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.7 3.3 GO:2000005 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.6 2.8 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.5 6.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.4 11.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.4 3.9 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.4 1.1 GO:0018963 phthalate metabolic process(GO:0018963)
0.3 1.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.3 1.5 GO:0019230 proprioception(GO:0019230)
0.3 1.8 GO:0061143 alveolar primary septum development(GO:0061143)
0.3 1.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.3 1.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 2.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 2.8 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 1.8 GO:0072675 osteoclast fusion(GO:0072675)
0.2 2.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 0.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.2 3.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.2 2.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.8 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 2.5 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 4.5 GO:0001502 cartilage condensation(GO:0001502)
0.1 0.5 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 2.6 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 7.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 8.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 1.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 2.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 4.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 1.8 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 2.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 0.3 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.1 1.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.5 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 1.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.2 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 2.0 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 3.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 2.2 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.5 GO:2001054 regulation of mesenchymal cell apoptotic process(GO:2001053) negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 6.7 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 1.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 5.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.8 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 2.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.2 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.9 GO:0035640 exploration behavior(GO:0035640)
0.0 0.9 GO:0003341 cilium movement(GO:0003341)
0.0 0.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 3.0 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 1.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 6.1 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 1.1 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 27.3 GO:0032982 myosin filament(GO:0032982)
0.7 11.0 GO:0097512 cardiac myofibril(GO:0097512)
0.5 1.4 GO:1990032 parallel fiber(GO:1990032)
0.5 1.4 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 2.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 3.0 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.2 0.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.2 5.9 GO:0005614 interstitial matrix(GO:0005614)
0.2 2.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 8.2 GO:0005605 basal lamina(GO:0005605)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 28.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 8.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.2 GO:0097427 microtubule bundle(GO:0097427)
0.1 9.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.3 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 6.6 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 10.9 GO:0045121 membrane raft(GO:0045121)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 2.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.8 GO:0002102 podosome(GO:0002102)
0.0 9.8 GO:0005938 cell cortex(GO:0005938)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 10.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.7 GO:0030426 growth cone(GO:0030426)
0.0 6.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.2 GO:0030118 clathrin coat(GO:0030118)
0.0 1.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 4.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.1 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.7 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
1.4 24.7 GO:1990459 transferrin receptor binding(GO:1990459)
1.1 27.3 GO:0031432 titin binding(GO:0031432)
0.9 3.7 GO:0030305 heparanase activity(GO:0030305)
0.7 6.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.6 12.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 7.7 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 11.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 1.4 GO:1990175 EH domain binding(GO:1990175)
0.3 3.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.3 8.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.2 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 3.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 2.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 7.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 1.2 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.2 1.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.6 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.2 0.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 1.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 4.8 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 4.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 14.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 3.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 2.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.3 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.1 2.6 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 3.0 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.8 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 3.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 2.1 GO:0000049 tRNA binding(GO:0000049)
0.0 3.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 5.9 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 2.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.2 GO:0019838 growth factor binding(GO:0019838)
0.0 0.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 32.0 PID BMP PATHWAY BMP receptor signaling
0.1 8.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 5.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 8.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 4.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 10.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 1.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 27.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 29.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 4.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 3.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 9.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 3.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 2.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 6.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.1 2.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.0 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway