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Results for HOXC6_HOXA7

Z-value: 0.99

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Transcription factors associated with HOXC6_HOXA7

Gene Symbol Gene ID Gene Info
ENSG00000197757.7 homeobox C6
ENSG00000122592.6 homeobox A7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA7hg19_v2_chr7_-_27196267_271963110.134.9e-01Click!
HOXC6hg19_v2_chr12_+_54422142_54422239-0.029.1e-01Click!

Activity profile of HOXC6_HOXA7 motif

Sorted Z-values of HOXC6_HOXA7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106552755 4.04 ENST00000390600.2
immunoglobulin heavy variable 3-9
chr14_-_106668095 3.50 ENST00000390606.2
immunoglobulin heavy variable 3-20
chr9_+_125132803 2.94 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_89327228 2.90 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr13_+_53602894 2.81 ENST00000219022.2
olfactomedin 4
chr2_+_90211643 2.79 ENST00000390277.2
immunoglobulin kappa variable 3D-11
chr9_+_125133315 2.78 ENST00000223423.4
ENST00000362012.2
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_90273679 2.43 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr9_+_125133467 2.34 ENST00000426608.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_90248739 2.31 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr15_+_58430567 1.83 ENST00000536493.1
aquaporin 9
chr6_+_130339710 1.76 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
l(3)mbt-like 3 (Drosophila)
chr4_+_151503077 1.73 ENST00000317605.4
mab-21-like 2 (C. elegans)
chr9_-_95166841 1.57 ENST00000262551.4
osteoglycin
chr11_+_59824060 1.55 ENST00000395032.2
ENST00000358152.2
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr11_+_59824127 1.51 ENST00000278865.3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr14_+_22465771 1.46 ENST00000390445.2
T cell receptor alpha variable 17
chr6_+_114178512 1.46 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr2_-_89340242 1.35 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_+_90198535 1.30 ENST00000390276.2
immunoglobulin kappa variable 1D-12
chr14_+_101295638 1.28 ENST00000523671.2
maternally expressed 3 (non-protein coding)
chr4_+_155484155 1.27 ENST00000509493.1
fibrinogen beta chain
chr3_+_149191723 1.25 ENST00000305354.4
transmembrane 4 L six family member 4
chr16_+_82068585 1.24 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_12059050 1.23 ENST00000396495.3
tumor necrosis factor receptor superfamily, member 17
chr12_+_56435637 1.21 ENST00000356464.5
ENST00000552361.1
ribosomal protein S26
chr19_+_50016610 1.19 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr18_-_44181442 1.19 ENST00000398722.4
lipoxygenase homology domains 1
chr1_-_92952433 1.12 ENST00000294702.5
growth factor independent 1 transcription repressor
chr6_+_26365387 1.11 ENST00000532865.1
ENST00000530653.1
ENST00000527417.1
butyrophilin, subfamily 3, member A2
chr18_-_47018869 1.10 ENST00000583036.1
ENST00000580261.1
ribosomal protein L17
chr3_+_111630451 1.10 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr3_-_191000172 1.09 ENST00000427544.2
urotensin 2B
chr4_+_155484103 1.09 ENST00000302068.4
fibrinogen beta chain
chr1_-_160924589 1.08 ENST00000368029.3
intelectin 2
chr14_-_106926724 1.08 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr6_+_26365443 1.02 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr17_-_46688334 1.02 ENST00000239165.7
homeobox B7
chr2_-_89161432 0.99 ENST00000390242.2
immunoglobulin kappa joining 1
chr18_-_47018897 0.97 ENST00000418495.1
ribosomal protein L17
chr12_-_10151773 0.96 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr2_+_152214098 0.93 ENST00000243347.3
tumor necrosis factor, alpha-induced protein 6
chr16_+_82068873 0.93 ENST00000566213.1
hydroxysteroid (17-beta) dehydrogenase 2
chr10_+_90660832 0.89 ENST00000371924.1
STAM binding protein-like 1
chr3_+_157154578 0.86 ENST00000295927.3
pentraxin 3, long
chr3_-_149093499 0.86 ENST00000472441.1
transmembrane 4 L six family member 1
chr7_+_150020329 0.85 ENST00000323078.7
leucine rich repeat containing 61
chr17_-_64225508 0.84 ENST00000205948.6
apolipoprotein H (beta-2-glycoprotein I)
chr18_-_61329118 0.83 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_+_221051699 0.82 ENST00000366903.6
H2.0-like homeobox
chr6_+_149721495 0.82 ENST00000326669.4
small ubiquitin-like modifier 4
chr2_+_234637754 0.82 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr16_+_12059091 0.80 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr17_+_61151306 0.80 ENST00000580068.1
ENST00000580466.1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_-_119759795 0.80 ENST00000419654.2
SEC24 family member D
chr14_-_94789663 0.79 ENST00000557225.1
ENST00000341584.3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr6_-_9933500 0.78 ENST00000492169.1
orofacial cleft 1 candidate 1
chr12_+_4385230 0.77 ENST00000536537.1
cyclin D2
chr6_+_26402517 0.75 ENST00000414912.2
butyrophilin, subfamily 3, member A1
chr8_-_133772794 0.73 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
transmembrane protein 71
chr11_-_102651343 0.73 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr11_-_104827425 0.70 ENST00000393150.3
caspase 4, apoptosis-related cysteine peptidase
chr6_+_26402465 0.69 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
butyrophilin, subfamily 3, member A1
chr12_-_10022735 0.69 ENST00000228438.2
C-type lectin domain family 2, member B
chr4_+_169418195 0.68 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr2_+_202098203 0.66 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
caspase 8, apoptosis-related cysteine peptidase
chr7_+_150020363 0.65 ENST00000359623.4
ENST00000493307.1
leucine rich repeat containing 61
chr15_+_69857515 0.62 ENST00000559477.1
RP11-279F6.1
chr3_+_152552685 0.61 ENST00000305097.3
purinergic receptor P2Y, G-protein coupled, 1
chr2_+_234621551 0.61 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr3_+_136649311 0.59 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr18_-_47018769 0.59 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr2_-_40680578 0.58 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr4_-_39979576 0.57 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr12_+_60083118 0.57 ENST00000261187.4
ENST00000543448.1
solute carrier family 16 (monocarboxylate transporter), member 7
chr16_-_28634874 0.57 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_-_112279694 0.55 ENST00000443596.1
ENST00000442119.1
MAPKAPK5 antisense RNA 1
chr4_+_141445333 0.55 ENST00000507667.1
ELMO/CED-12 domain containing 2
chr9_-_95166976 0.54 ENST00000447356.1
osteoglycin
chr1_-_232651312 0.52 ENST00000262861.4
signal-induced proliferation-associated 1 like 2
chr2_-_176046391 0.52 ENST00000392541.3
ENST00000409194.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr2_+_228736335 0.51 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr12_-_91573316 0.50 ENST00000393155.1
decorin
chr17_+_57233087 0.50 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr6_-_36515177 0.49 ENST00000229812.7
serine/threonine kinase 38
chr4_+_108745711 0.48 ENST00000394684.4
sphingomyelin synthase 2
chr4_-_138453559 0.48 ENST00000511115.1
protocadherin 18
chr6_+_46761118 0.48 ENST00000230588.4
meprin A, alpha (PABA peptide hydrolase)
chr2_+_25015968 0.48 ENST00000380834.2
ENST00000473706.1
centromere protein O
chr7_+_93551011 0.47 ENST00000248564.5
guanine nucleotide binding protein (G protein), gamma 11
chr2_+_26624775 0.47 ENST00000288710.2
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr8_-_133772870 0.47 ENST00000522334.1
ENST00000519016.1
transmembrane protein 71
chr15_+_96904487 0.47 ENST00000600790.1
Uncharacterized protein
chr3_+_111718036 0.47 ENST00000455401.2
transgelin 3
chr13_+_31309645 0.45 ENST00000380490.3
arachidonate 5-lipoxygenase-activating protein
chr2_-_151395525 0.45 ENST00000439275.1
Rho family GTPase 3
chr14_+_62164340 0.44 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr6_-_133035185 0.44 ENST00000367928.4
vanin 1
chr3_+_111717511 0.43 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr2_+_202047843 0.43 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
caspase 10, apoptosis-related cysteine peptidase
chr3_+_111717600 0.41 ENST00000273368.4
transgelin 3
chr5_+_40909354 0.41 ENST00000313164.9
complement component 7
chrX_-_110655306 0.41 ENST00000371993.2
doublecortin
chr1_+_117544366 0.40 ENST00000256652.4
ENST00000369470.1
CD101 molecule
chr8_-_62602327 0.40 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
aspartate beta-hydroxylase
chrX_-_77225135 0.39 ENST00000458128.1
phosphoglycerate mutase family member 4
chr2_+_202098166 0.39 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
caspase 8, apoptosis-related cysteine peptidase
chr4_-_138453606 0.38 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr4_-_120243545 0.37 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr3_+_132316081 0.37 ENST00000249887.2
atypical chemokine receptor 4
chr12_-_50643664 0.36 ENST00000550592.1
LIM domain and actin binding 1
chr3_+_111718173 0.36 ENST00000494932.1
transgelin 3
chr12_-_91573132 0.35 ENST00000550563.1
ENST00000546370.1
decorin
chr7_-_44580861 0.35 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1-like 1
chr6_+_152128371 0.34 ENST00000443427.1
estrogen receptor 1
chr3_-_167191814 0.34 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr16_-_28937027 0.32 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr19_+_50016411 0.32 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
Fc fragment of IgG, receptor, transporter, alpha
chr5_+_96840389 0.32 ENST00000504012.1
RP11-1E3.1
chr19_+_49199209 0.31 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr1_+_225600404 0.31 ENST00000366845.2
AC092811.1
chr5_-_173217931 0.31 ENST00000522731.1
CTB-43E15.4
chr11_+_33061543 0.31 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
t-complex 11, testis-specific-like 1
chr18_-_70211691 0.31 ENST00000269503.4
cerebellin 2 precursor
chr12_+_131438443 0.30 ENST00000261654.5
G protein-coupled receptor 133
chr2_-_134326009 0.30 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr14_-_101295407 0.30 ENST00000596284.1
AL117190.2
chr6_-_138866823 0.30 ENST00000342260.5
NHS-like 1
chr6_-_138833630 0.29 ENST00000533765.1
NHS-like 1
chr5_+_54455946 0.29 ENST00000503787.1
ENST00000296734.6
ENST00000515370.1
glutathione peroxidase 8 (putative)
chr4_+_169418255 0.29 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr12_-_89919765 0.29 ENST00000541909.1
ENST00000313546.3
POC1 centriolar protein B
chr6_+_26440700 0.29 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr14_-_23058063 0.27 ENST00000538631.1
ENST00000543337.1
ENST00000250498.4
defender against cell death 1
chr4_-_16675930 0.26 ENST00000503178.2
LIM domain binding 2
chr7_+_134528635 0.26 ENST00000445569.2
caldesmon 1
chr1_-_201140673 0.26 ENST00000367333.2
transmembrane protein 9
chr11_-_8857248 0.25 ENST00000534248.1
ENST00000530959.1
ENST00000531578.1
ENST00000533225.1
suppression of tumorigenicity 5
chr19_+_49404041 0.25 ENST00000263273.5
ENST00000424608.1
nucleobindin 1
chr12_+_131438496 0.25 ENST00000543826.1
G protein-coupled receptor 133
chr3_+_138340049 0.25 ENST00000464668.1
Fas apoptotic inhibitory molecule
chr7_-_22862448 0.25 ENST00000358435.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr1_+_66820058 0.25 ENST00000480109.2
phosphodiesterase 4B, cAMP-specific
chr3_-_164796269 0.24 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr4_-_152149033 0.24 ENST00000514152.1
SH3 domain containing 19
chr9_-_215744 0.24 ENST00000382387.2
chromosome 9 open reading frame 66
chr17_+_4692230 0.24 ENST00000331264.7
glycolipid transfer protein domain containing 2
chr20_+_15177480 0.23 ENST00000402914.1
MACRO domain containing 2
chr11_-_49230084 0.23 ENST00000356696.3
folate hydrolase (prostate-specific membrane antigen) 1
chr12_-_10282836 0.23 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr12_-_94673956 0.23 ENST00000551941.1
Uncharacterized protein
chr11_-_63376013 0.23 ENST00000540943.1
phospholipase A2, group XVI
chr4_-_87281196 0.22 ENST00000359221.3
mitogen-activated protein kinase 10
chr14_-_54425475 0.22 ENST00000559642.1
bone morphogenetic protein 4
chr12_-_91573249 0.22 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr14_-_23426270 0.22 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS augmin-like complex, subunit 4
chr6_+_152128325 0.22 ENST00000446550.1
estrogen receptor 1
chr6_+_28092338 0.22 ENST00000340487.4
zinc finger and SCAN domain containing 16
chr14_-_23426231 0.22 ENST00000556915.1
HAUS augmin-like complex, subunit 4
chr19_-_54618650 0.21 ENST00000391757.1
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr1_+_202317815 0.21 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
protein phosphatase 1, regulatory subunit 12B
chr14_-_23426337 0.21 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS augmin-like complex, subunit 4
chr4_-_74486109 0.21 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr12_-_89920030 0.21 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr7_-_22862406 0.21 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr8_-_41166953 0.21 ENST00000220772.3
secreted frizzled-related protein 1
chr14_-_23426322 0.20 ENST00000555367.1
HAUS augmin-like complex, subunit 4
chr17_-_39324424 0.20 ENST00000391356.2
keratin associated protein 4-3
chr4_-_87281224 0.20 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr11_-_107729887 0.20 ENST00000525815.1
solute carrier family 35, member F2
chr12_-_10282742 0.20 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
C-type lectin domain family 7, member A
chr17_-_39254391 0.20 ENST00000333822.4
keratin associated protein 4-8
chr5_-_22853429 0.20 ENST00000504376.2
cadherin 12, type 2 (N-cadherin 2)
chr11_-_49230184 0.20 ENST00000340334.7
ENST00000256999.2
folate hydrolase (prostate-specific membrane antigen) 1
chr20_+_43849941 0.19 ENST00000372769.3
semenogelin II
chr16_+_53469525 0.19 ENST00000544405.2
retinoblastoma-like 2 (p130)
chr11_+_2405833 0.19 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr12_+_78359999 0.19 ENST00000550503.1
neuron navigator 3
chr11_-_111649074 0.19 ENST00000534218.1
RP11-108O10.2
chrX_-_16887963 0.18 ENST00000380084.4
retinoblastoma binding protein 7
chr19_-_5903714 0.18 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr3_-_194188956 0.17 ENST00000256031.4
ENST00000446356.1
ATPase type 13A3
chr12_-_10282681 0.17 ENST00000533022.1
C-type lectin domain family 7, member A
chr8_-_82373809 0.17 ENST00000379071.2
fatty acid binding protein 9, testis
chr2_+_202047596 0.17 ENST00000286186.6
ENST00000360132.3
caspase 10, apoptosis-related cysteine peptidase
chr10_-_101825151 0.16 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr14_+_72399833 0.16 ENST00000553530.1
ENST00000556437.1
regulator of G-protein signaling 6
chr11_-_49230144 0.16 ENST00000343844.4
folate hydrolase (prostate-specific membrane antigen) 1
chr17_-_72772462 0.16 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr7_+_129906660 0.16 ENST00000222481.4
carboxypeptidase A2 (pancreatic)
chr5_+_66300446 0.16 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr8_+_39972170 0.15 ENST00000521257.1
RP11-359E19.2
chr11_+_86748863 0.15 ENST00000340353.7
transmembrane protein 135
chr17_-_76220740 0.14 ENST00000600484.1
Uncharacterized protein
chr7_+_141811539 0.14 ENST00000550469.2
ENST00000477922.3
Putative inactive maltase-glucoamylase-like protein LOC93432
chr12_+_64798095 0.14 ENST00000332707.5
exportin, tRNA
chr9_-_20382446 0.14 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr12_-_52995291 0.14 ENST00000293745.2
ENST00000354310.4
keratin 72
chr3_+_138340067 0.14 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr11_+_121447469 0.13 ENST00000532694.1
ENST00000534286.1
sortilin-related receptor, L(DLR class) A repeats containing

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.4 1.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.4 8.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.3 1.8 GO:0015722 canalicular bile acid transport(GO:0015722) pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.3 1.4 GO:0070980 biphenyl catabolic process(GO:0070980)
0.3 2.8 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.3 1.9 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 0.8 GO:0035425 autocrine signaling(GO:0035425)
0.2 0.6 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 2.4 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.6 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 1.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 3.6 GO:0072643 interferon-gamma secretion(GO:0072643)
0.1 0.2 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.2 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.1 2.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.8 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 2.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.4 GO:0070101 B-1 B cell homeostasis(GO:0001922) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 2.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 14.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.6 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.8 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.7 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.6 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.8 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0072200 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.5 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.0 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.0 1.0 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0030070 insulin processing(GO:0030070)
0.0 0.5 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 7.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.4 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 1.2 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.8 GO:0030728 ovulation(GO:0030728)
0.0 1.0 GO:0030220 platelet formation(GO:0030220)
0.0 2.0 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.0 0.1 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.8 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.6 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.9 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.3 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.2 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.0 0.5 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.2 GO:0042246 tissue regeneration(GO:0042246)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0042585 germinal vesicle(GO:0042585)
0.2 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 4.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 1.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 1.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 7.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 4.6 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 2.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 4.2 GO:0072562 blood microparticle(GO:0072562)
0.0 1.2 GO:0032420 stereocilium(GO:0032420)
0.0 3.1 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 8.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.4 1.8 GO:0015254 glycerol channel activity(GO:0015254)
0.4 2.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.3 1.5 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.6 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.2 0.6 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.6 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 0.6 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.4 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.8 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 21.9 GO:0003823 antigen binding(GO:0003823)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.6 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0015266 protein channel activity(GO:0015266)
0.0 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.6 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 1.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 7.3 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 3.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha