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Illumina Body Map 2

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Results for HOXD1

Z-value: 0.77

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Transcription factors associated with HOXD1

Gene Symbol Gene ID Gene Info
ENSG00000128645.11 homeobox D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD1hg19_v2_chr2_+_177053307_1770534020.318.2e-02Click!

Activity profile of HOXD1 motif

Sorted Z-values of HOXD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_26593649 4.37 ENST00000455601.2
mucin 15, cell surface associated
chr11_-_26593779 4.28 ENST00000529533.1
mucin 15, cell surface associated
chr11_-_26593677 3.77 ENST00000527569.1
mucin 15, cell surface associated
chr8_+_92261516 2.95 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr11_+_65554493 2.00 ENST00000335987.3
ovo-like zinc finger 1
chr11_+_71900703 1.87 ENST00000393681.2
folate receptor 1 (adult)
chr2_+_135596180 1.85 ENST00000283054.4
ENST00000392928.1
aminocarboxymuconate semialdehyde decarboxylase
chr2_+_135596106 1.83 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr11_+_71900572 1.81 ENST00000312293.4
folate receptor 1 (adult)
chr6_+_78400375 1.80 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr7_-_73256838 1.37 ENST00000297873.4
Williams Beuren syndrome chromosome region 27
chr5_+_176811431 1.37 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr20_-_50419055 1.23 ENST00000217086.4
spalt-like transcription factor 4
chr3_-_151034734 1.22 ENST00000260843.4
G protein-coupled receptor 87
chr11_-_102651343 1.08 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chr7_+_133812052 1.02 ENST00000285928.2
leucine-rich repeats and guanylate kinase domain containing
chr20_-_50418972 0.97 ENST00000395997.3
spalt-like transcription factor 4
chr1_-_190446759 0.95 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chrX_+_43515467 0.93 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr8_+_55528627 0.93 ENST00000220676.1
retinitis pigmentosa 1 (autosomal dominant)
chr3_-_126327398 0.90 ENST00000383572.2
thioredoxin reductase 3 neighbor
chr3_+_2933893 0.89 ENST00000397459.2
contactin 4
chr11_+_101918153 0.87 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
chromosome 11 open reading frame 70
chr4_-_150736962 0.85 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1
chr14_+_20187174 0.83 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chrX_+_114827818 0.82 ENST00000420625.2
plastin 3
chr8_-_49834299 0.81 ENST00000396822.1
snail family zinc finger 2
chr20_-_50418947 0.78 ENST00000371539.3
spalt-like transcription factor 4
chr4_-_139051839 0.77 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
long intergenic non-protein coding RNA 616
chr4_+_105828492 0.76 ENST00000506148.1
RP11-556I14.1
chr2_+_78143006 0.75 ENST00000443419.1
AC073628.1
chr15_+_63050785 0.70 ENST00000472902.1
talin 2
chr19_-_36001113 0.69 ENST00000434389.1
dermokine
chr8_-_49833978 0.67 ENST00000020945.1
snail family zinc finger 2
chr12_-_23737534 0.67 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr4_-_74486109 0.62 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chrX_-_19504642 0.61 ENST00000469203.2
mitogen-activated protein kinase kinase kinase 15
chr11_+_118398178 0.60 ENST00000302783.4
ENST00000539546.1
tetratricopeptide repeat domain 36
chr4_+_105828537 0.59 ENST00000515649.1
RP11-556I14.1
chr1_-_201140673 0.52 ENST00000367333.2
transmembrane protein 9
chr3_-_99569821 0.51 ENST00000487087.1
filamin A interacting protein 1-like
chr4_-_138453606 0.51 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr4_-_74486217 0.49 ENST00000335049.5
ENST00000307439.5
Ras association (RalGDS/AF-6) domain family member 6
chr17_-_10372875 0.49 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr16_-_52061283 0.48 ENST00000566314.1
chromosome 16 open reading frame 97
chr5_-_96478466 0.47 ENST00000274382.4
Lix1 homolog (chicken)
chr7_+_37723420 0.44 ENST00000476620.1
ependymin related 1
chr15_+_58702742 0.43 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr4_+_86748898 0.43 ENST00000509300.1
Rho GTPase activating protein 24
chr9_+_124329336 0.42 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chr4_-_138453559 0.41 ENST00000511115.1
protocadherin 18
chr10_+_99205959 0.40 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr5_-_96478457 0.39 ENST00000512378.1
Lix1 homolog (chicken)
chr4_-_74486347 0.32 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr9_-_5339873 0.32 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr10_+_99205894 0.30 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr4_-_146261573 0.30 ENST00000610239.1
RP11-142A22.4
chr6_+_130742231 0.29 ENST00000545622.1
transmembrane protein 200A
chr7_-_81399438 0.29 ENST00000222390.5
hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_+_43990576 0.28 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr11_+_4615269 0.26 ENST00000530443.2
olfactory receptor, family 52, subfamily I, member 1
chr15_-_37393406 0.26 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr11_-_102709441 0.22 ENST00000434103.1
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_38956205 0.22 ENST00000306658.7
keratin 28
chr11_-_74800799 0.22 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chr18_-_33709268 0.21 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr4_+_86749045 0.18 ENST00000514229.1
Rho GTPase activating protein 24
chr11_-_95657231 0.17 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
myotubularin related protein 2
chr14_+_60386853 0.17 ENST00000570145.1
leucine rich repeat containing 9
chr11_-_124190184 0.16 ENST00000357438.2
olfactory receptor, family 8, subfamily D, member 2
chr7_-_99716940 0.13 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_113568207 0.13 ENST00000511529.1
La ribonucleoprotein domain family, member 7
chr7_-_99717463 0.12 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_-_99716952 0.11 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr7_+_148287657 0.11 ENST00000307003.2
chromosome 7 open reading frame 33
chrX_+_107288239 0.11 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr11_+_4615037 0.10 ENST00000450052.2
olfactory receptor, family 52, subfamily I, member 1
chr11_+_60163775 0.10 ENST00000300187.6
ENST00000395005.2
membrane-spanning 4-domains, subfamily A, member 14
chr19_+_11071546 0.09 ENST00000358026.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr19_-_3557570 0.08 ENST00000355415.2
major facilitator superfamily domain containing 12
chr22_-_28490123 0.07 ENST00000442232.1
tetratricopeptide repeat domain 28
chr1_-_151431909 0.07 ENST00000361398.3
ENST00000271715.2
pogo transposable element with ZNF domain
chr12_+_10163231 0.07 ENST00000396502.1
ENST00000338896.5
C-type lectin domain family 12, member B
chr1_-_112032284 0.06 ENST00000414219.1
adenosine A3 receptor
chr12_-_52761262 0.06 ENST00000257901.3
keratin 85
chr2_+_228736335 0.06 ENST00000440997.1
ENST00000545118.1
dynein assembly factor with WDR repeat domains 1
chr11_-_71823796 0.05 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
anaphase promoting complex subunit 15
chr2_+_191221240 0.05 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chrX_+_107288197 0.05 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr12_-_53171128 0.04 ENST00000332411.2
keratin 76
chr5_+_63802109 0.03 ENST00000334025.2
regulator of G-protein signaling 7 binding protein
chr7_-_81399329 0.03 ENST00000453411.1
ENST00000444829.2
hepatocyte growth factor (hepapoietin A; scatter factor)
chr18_-_44181442 0.03 ENST00000398722.4
lipoxygenase homology domains 1
chr1_+_12834984 0.02 ENST00000357726.4
PRAME family member 12
chr1_-_151431674 0.01 ENST00000531094.1
pogo transposable element with ZNF domain

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 3.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.5 1.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.5 1.4 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.4 2.0 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.4 1.8 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 3.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 2.9 GO:0019532 oxalate transport(GO:0019532)
0.1 12.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.9 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.9 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.9 GO:0097352 autophagosome maturation(GO:0097352)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 1.0 GO:0002177 manchette(GO:0002177)
0.1 12.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.8 GO:0000800 lateral element(GO:0000800)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 3.0 GO:0000792 heterochromatin(GO:0000792)
0.0 0.9 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.5 GO:0032982 myosin filament(GO:0032982)
0.0 1.3 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 2.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 3.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 3.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.5 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 11.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 3.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 3.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane