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Illumina Body Map 2
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Results for INSM1
Z-value: 1.25
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Transcription factors associated with INSM1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| INSM1 | hg19_v2_chr20_+_20348740_20348765 | 0.42 | 1.7e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of INSM1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 7.2 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.1 | 5.6 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.3 | 5.2 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 1.7 | 5.0 | GO:0040040 | thermosensory behavior(GO:0040040) |
| 0.9 | 4.4 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.8 | 4.2 | GO:0030382 | sperm mitochondrion organization(GO:0030382) |
| 0.0 | 3.7 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
| 0.8 | 3.1 | GO:0036071 | N-glycan fucosylation(GO:0036071) |
| 0.1 | 2.9 | GO:0051573 | negative regulation of histone H3-K9 methylation(GO:0051573) |
| 0.1 | 2.9 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.4 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 4.8 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 4.4 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 4.2 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.0 | 4.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 3.3 | GO:0043679 | axon terminus(GO:0043679) |
| 0.9 | 2.7 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.0 | 2.1 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 2.0 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.0 | 1.5 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 7.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 0.1 | 5.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.9 | 5.2 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 0.4 | 5.0 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 1.5 | 4.4 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.0 | 4.0 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.5 | 3.3 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.8 | 3.1 | GO:0008424 | glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921) |
| 0.4 | 2.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.5 | 2.6 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 2.0 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.6 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 1.6 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 1.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.1 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.0 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.0 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.1 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.0 | 5.6 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 4.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 3.7 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 3.4 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.1 | 3.1 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.0 | 2.3 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 2.0 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 2.0 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |