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Illumina Body Map 2

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Results for LMX1B_MNX1_RAX2

Z-value: 0.73

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Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
ENSG00000136944.13 LIM homeobox transcription factor 1 beta
ENSG00000130675.10 motor neuron and pancreas homeobox 1
ENSG00000173976.11 retina and anterior neural fold homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MNX1hg19_v2_chr7_-_156803329_1568033620.664.4e-05Click!
LMX1Bhg19_v2_chr9_+_129376722_1293767480.531.7e-03Click!
RAX2hg19_v2_chr19_-_3772209_37722360.193.1e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_24298531 3.31 ENST00000175238.6
ADAM metallopeptidase domain 7
chr8_+_24298597 2.95 ENST00000380789.1
ADAM metallopeptidase domain 7
chr15_+_48483736 2.65 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr3_+_173116225 2.50 ENST00000457714.1
neuroligin 1
chr7_-_92855762 2.43 ENST00000453812.2
ENST00000394468.2
HEPACAM family member 2
chr4_+_169418195 2.08 ENST00000261509.6
ENST00000335742.7
palladin, cytoskeletal associated protein
chr12_+_41831485 2.07 ENST00000539469.2
ENST00000298919.7
PDZ domain containing ring finger 4
chr4_-_138453606 2.05 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
protocadherin 18
chr17_-_46690839 2.04 ENST00000498634.2
homeobox B8
chr16_-_29910853 2.01 ENST00000308713.5
seizure related 6 homolog (mouse)-like 2
chr18_+_76740189 1.88 ENST00000537592.2
ENST00000575389.2
spalt-like transcription factor 3
chr8_+_24298438 1.85 ENST00000441335.2
ADAM metallopeptidase domain 7
chr5_+_174151536 1.79 ENST00000239243.6
ENST00000507785.1
msh homeobox 2
chr1_-_234667504 1.70 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
chrX_+_99839799 1.49 ENST00000373031.4
tenomodulin
chr6_-_87804815 1.49 ENST00000369582.2
glycoprotein hormones, alpha polypeptide
chr3_-_151034734 1.47 ENST00000260843.4
G protein-coupled receptor 87
chr7_-_107443652 1.46 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr8_+_50824233 1.45 ENST00000522124.1
syntrophin, gamma 1
chr6_+_78400375 1.43 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr4_-_138453559 1.36 ENST00000511115.1
protocadherin 18
chrY_-_13524717 1.34 ENST00000331172.6
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1 pseudogene 1
chr15_-_37393406 1.30 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
Meis homeobox 2
chr4_+_169418255 1.28 ENST00000505667.1
ENST00000511948.1
palladin, cytoskeletal associated protein
chr17_+_56833184 1.27 ENST00000308249.2
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr1_-_101360331 1.26 ENST00000416479.1
ENST00000370113.3
exostosin-like glycosyltransferase 2
chr5_-_24645078 1.20 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chr1_-_101360205 1.12 ENST00000450240.1
exostosin-like glycosyltransferase 2
chr1_-_190446759 1.11 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr13_+_53602894 1.09 ENST00000219022.2
olfactomedin 4
chrX_-_10851762 1.08 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr8_+_105235572 1.08 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr15_+_76352178 1.07 ENST00000388942.3
chromosome 15 open reading frame 27
chr5_+_176811431 1.07 ENST00000512593.1
ENST00000324417.5
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr9_+_12693336 1.05 ENST00000381137.2
ENST00000388918.5
tyrosinase-related protein 1
chr8_-_109799793 1.04 ENST00000297459.3
transmembrane protein 74
chr12_-_10978957 1.03 ENST00000240619.2
taste receptor, type 2, member 10
chr7_+_134464376 1.02 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr9_-_95166841 1.02 ENST00000262551.4
osteoglycin
chrX_-_13835147 1.01 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr12_+_26348246 1.01 ENST00000422622.2
sarcospan
chr7_-_130080977 0.99 ENST00000223208.5
centrosomal protein 41kDa
chr9_-_95166884 0.98 ENST00000375561.5
osteoglycin
chr1_-_101360374 0.96 ENST00000535414.1
exostosin-like glycosyltransferase 2
chr1_+_152943122 0.96 ENST00000328051.2
small proline-rich protein 4
chr18_+_32173276 0.94 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr4_+_114214125 0.94 ENST00000509550.1
ankyrin 2, neuronal
chr4_-_20985632 0.92 ENST00000359001.5
Kv channel interacting protein 4
chr13_-_36788718 0.92 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr11_-_26744908 0.92 ENST00000533617.1
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
chr1_-_242612779 0.91 ENST00000427495.1
phospholipase D family, member 5
chr11_-_129062093 0.91 ENST00000310343.9
Rho GTPase activating protein 32
chr20_-_29978383 0.91 ENST00000339144.3
ENST00000376321.3
defensin, beta 119
chr1_+_160370344 0.89 ENST00000368061.2
VANGL planar cell polarity protein 2
chr1_-_185597619 0.87 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
chr5_+_31193847 0.86 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chr13_-_86373536 0.85 ENST00000400286.2
SLIT and NTRK-like family, member 6
chr5_+_126984710 0.84 ENST00000379445.3
cortexin 3
chr4_+_105828537 0.82 ENST00000515649.1
RP11-556I14.1
chr4_+_71108300 0.81 ENST00000304954.3
casein kappa
chr4_+_105828492 0.81 ENST00000506148.1
RP11-556I14.1
chr3_-_12587055 0.81 ENST00000564146.3
chromosome 3 open reading frame 83
chr2_+_3800169 0.80 ENST00000399143.3
doublecortin domain containing 2C
chr1_-_204135450 0.79 ENST00000272190.8
ENST00000367195.2
renin
chr3_+_111717511 0.78 ENST00000478951.1
ENST00000393917.2
transgelin 3
chr8_-_1922789 0.78 ENST00000521498.1
RP11-439C15.4
chr12_+_26348429 0.77 ENST00000242729.2
sarcospan
chr20_-_56647116 0.75 ENST00000441277.2
ENST00000452842.1
RP13-379L11.1
chr17_-_38859996 0.75 ENST00000264651.2
keratin 24
chr12_-_6233828 0.75 ENST00000572068.1
ENST00000261405.5
von Willebrand factor
chr20_-_29978286 0.75 ENST00000376315.2
defensin, beta 119
chr2_+_149974684 0.74 ENST00000450639.1
LY6/PLAUR domain containing 6B
chr18_+_34124507 0.74 ENST00000591635.1
formin homology 2 domain containing 3
chr1_-_94586651 0.73 ENST00000535735.1
ENST00000370225.3
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_31107127 0.71 ENST00000259845.4
psoriasis susceptibility 1 candidate 2
chr11_-_16419067 0.67 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr4_+_69313145 0.66 ENST00000305363.4
transmembrane protease, serine 11E
chr1_+_160160283 0.66 ENST00000368079.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_149293990 0.64 ENST00000472417.1
WW domain containing transcription regulator 1
chr7_+_134464414 0.64 ENST00000361901.2
caldesmon 1
chr7_-_107642348 0.63 ENST00000393561.1
laminin, beta 1
chr12_-_94673956 0.63 ENST00000551941.1
Uncharacterized protein
chr2_+_179318295 0.61 ENST00000442710.1
deafness, autosomal recessive 59
chr11_-_102576537 0.61 ENST00000260229.4
matrix metallopeptidase 27
chr12_+_26348582 0.61 ENST00000535504.1
sarcospan
chr10_+_45406627 0.61 ENST00000389583.4
transmembrane protein 72
chr5_-_147286065 0.61 ENST00000318315.4
ENST00000515291.1
chromosome 5 open reading frame 46
chr1_+_160160346 0.59 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_+_111717600 0.59 ENST00000273368.4
transgelin 3
chr5_-_36301984 0.59 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chrX_-_139047669 0.57 ENST00000370540.1
chromosome X open reading frame 66
chr1_+_107683436 0.56 ENST00000370068.1
netrin G1
chr1_-_95783809 0.56 ENST00000423410.1
RP4-586O15.1
chr6_-_100912785 0.56 ENST00000369208.3
single-minded family bHLH transcription factor 1
chr1_+_107682629 0.55 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
netrin G1
chr9_-_95166976 0.55 ENST00000447356.1
osteoglycin
chr3_+_111718036 0.54 ENST00000455401.2
transgelin 3
chr2_+_177015122 0.54 ENST00000468418.3
homeobox D3
chr15_+_69857515 0.53 ENST00000559477.1
RP11-279F6.1
chr12_-_52967600 0.53 ENST00000549343.1
ENST00000305620.2
keratin 74
chr1_-_242612726 0.52 ENST00000459864.1
phospholipase D family, member 5
chr8_-_139926236 0.52 ENST00000303045.6
ENST00000435777.1
collagen, type XXII, alpha 1
chr4_-_87028478 0.51 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr12_-_112123524 0.50 ENST00000327551.6
BRCA1 associated protein
chr22_-_28490123 0.50 ENST00000442232.1
tetratricopeptide repeat domain 28
chr2_+_78143006 0.48 ENST00000443419.1
AC073628.1
chr10_+_24497704 0.47 ENST00000376456.4
ENST00000458595.1
KIAA1217
chr14_+_65016620 0.47 ENST00000298705.1
protein phosphatase 1, regulatory subunit 36
chr6_+_105404899 0.46 ENST00000345080.4
lin-28 homolog B (C. elegans)
chr12_-_91573132 0.44 ENST00000550563.1
ENST00000546370.1
decorin
chr7_-_83278322 0.44 ENST00000307792.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr10_-_75351088 0.44 ENST00000451492.1
ENST00000413442.1
ubiquitin specific peptidase 54
chr16_-_14109841 0.44 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
chr13_-_44735393 0.43 ENST00000400419.1
small integral membrane protein 2
chr12_-_91573249 0.43 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
decorin
chr14_-_21058982 0.43 ENST00000556526.1
ribonuclease, RNase A family, 12 (non-active)
chr1_+_115572415 0.43 ENST00000256592.1
thyroid stimulating hormone, beta
chr4_-_186696425 0.43 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
sorbin and SH3 domain containing 2
chr14_+_23709555 0.43 ENST00000430154.2
chromosome 14 open reading frame 164
chr21_-_42219065 0.43 ENST00000400454.1
Down syndrome cell adhesion molecule
chr21_+_35736302 0.43 ENST00000290310.3
potassium voltage-gated channel, Isk-related family, member 2
chr10_+_115511434 0.42 ENST00000369312.4
pleckstrin homology domain containing, family S member 1
chr2_-_50574856 0.42 ENST00000342183.5
neurexin 1
chr5_+_61874562 0.40 ENST00000334994.5
ENST00000409534.1
leucine rich repeat containing 70
importin 11
chr21_+_17442799 0.40 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
long intergenic non-protein coding RNA 478
chr12_+_54410664 0.39 ENST00000303406.4
homeobox C4
chr6_-_167797887 0.39 ENST00000476779.2
ENST00000460930.2
ENST00000397829.4
ENST00000366827.2
t-complex 10
chr8_+_117950422 0.39 ENST00000378279.3
alanine and arginine rich domain containing protein
chr5_+_166711804 0.39 ENST00000518659.1
ENST00000545108.1
teneurin transmembrane protein 2
chr19_-_14064114 0.39 ENST00000585607.1
ENST00000538517.2
ENST00000587458.1
ENST00000538371.2
podocan-like 1
chr9_+_12695702 0.39 ENST00000381136.2
tyrosinase-related protein 1
chr4_+_147145709 0.38 ENST00000504313.1
Uncharacterized protein
chr13_+_34922173 0.38 ENST00000605909.1
RP11-16D22.2
chr3_-_157221128 0.38 ENST00000392833.2
ENST00000362010.2
ventricular zone expressed PH domain-containing 1
chr5_+_61874696 0.38 ENST00000491184.2
leucine rich repeat containing 70
chr4_+_88571429 0.38 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr10_+_115511213 0.37 ENST00000361048.1
pleckstrin homology domain containing, family S member 1
chr7_+_129984630 0.37 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr3_-_79816965 0.37 ENST00000464233.1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr7_-_84121858 0.36 ENST00000448879.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_-_7697857 0.36 ENST00000598935.1
Purkinje cell protein 2
chr5_-_126409159 0.36 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
chromosome 5 open reading frame 63
chr3_+_115342349 0.36 ENST00000393780.3
growth associated protein 43
chr9_-_28670283 0.36 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr6_-_76072719 0.35 ENST00000370020.1
filamin A interacting protein 1
chr10_+_32873190 0.35 ENST00000375025.4
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr3_-_20053741 0.35 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr18_+_5748793 0.35 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
chr6_+_153071925 0.35 ENST00000367244.3
ENST00000367243.3
vasoactive intestinal peptide
chr10_+_118083919 0.35 ENST00000333254.3
coiled-coil domain containing 172
chr11_-_124190184 0.34 ENST00000357438.2
olfactory receptor, family 8, subfamily D, member 2
chr17_+_72427477 0.34 ENST00000342648.5
ENST00000481232.1
G protein-coupled receptor, family C, group 5, member C
chr3_-_164796269 0.33 ENST00000264382.3
sucrase-isomaltase (alpha-glucosidase)
chr2_-_180610767 0.33 ENST00000409343.1
zinc finger protein 385B
chr1_+_40713573 0.33 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr9_+_130026756 0.33 ENST00000314904.5
ENST00000373387.4
GTPase activating Rap/RanGAP domain-like 3
chr1_+_107683644 0.32 ENST00000370067.1
netrin G1
chr7_-_99716940 0.32 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr2_+_187454749 0.32 ENST00000261023.3
ENST00000374907.3
integrin, alpha V
chr6_+_4087664 0.31 ENST00000430835.2
chromosome 6 open reading frame 201
chr6_-_49937338 0.31 ENST00000398718.1
defensin, beta 113
chr4_+_169633310 0.31 ENST00000510998.1
palladin, cytoskeletal associated protein
chr7_+_97361388 0.31 ENST00000350485.4
ENST00000346867.4
tachykinin, precursor 1
chr18_+_68002675 0.31 ENST00000584919.1
Uncharacterized protein
chr12_+_78359999 0.30 ENST00000550503.1
neuron navigator 3
chr14_+_32798547 0.30 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr1_+_68150744 0.30 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr14_+_32798462 0.30 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr18_-_33709268 0.30 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chr2_-_190927447 0.30 ENST00000260950.4
myostatin
chr5_+_53751445 0.30 ENST00000302005.1
heat shock 27kDa protein 3
chr1_-_67266939 0.30 ENST00000304526.2
insulin-like 5
chr7_-_111032971 0.30 ENST00000450877.1
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr19_-_56110859 0.29 ENST00000221665.3
ENST00000592585.1
FLT3-interacting zinc finger 1
chr1_-_186430222 0.29 ENST00000391997.2
phosducin
chr11_-_4719072 0.29 ENST00000396950.3
ENST00000532598.1
olfactory receptor, family 51, subfamily E, member 2
chr9_-_98189055 0.29 ENST00000433644.2
RP11-435O5.2
chr1_-_227505289 0.29 ENST00000366765.3
CDC42 binding protein kinase alpha (DMPK-like)
chr12_-_16759440 0.28 ENST00000537304.1
LIM domain only 3 (rhombotin-like 2)
chr12_-_86650077 0.28 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chrM_+_10053 0.28 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr19_-_7698599 0.28 ENST00000311069.5
Purkinje cell protein 2
chr11_-_30608413 0.28 ENST00000528686.1
metallophosphoesterase domain containing 2
chr17_+_42785976 0.28 ENST00000393547.2
ENST00000398338.3
DBF4 homolog B (S. cerevisiae)
chr1_+_50569575 0.27 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr2_+_171034646 0.27 ENST00000409044.3
ENST00000408978.4
myosin IIIB
chr6_+_12290586 0.27 ENST00000379375.5
endothelin 1
chr20_-_50722183 0.26 ENST00000371523.4
ZFP64 zinc finger protein
chr7_-_99716952 0.26 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_-_46716647 0.26 ENST00000608940.1
RP11-357H14.17
chrM_+_7586 0.26 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr5_-_1882858 0.26 ENST00000511126.1
ENST00000231357.2
iroquois homeobox 4
chr4_+_3388057 0.26 ENST00000538395.1
regulator of G-protein signaling 12
chr7_-_99717463 0.26 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_+_155538093 0.25 ENST00000462408.2
T-cell lymphoma invasion and metastasis 2
chr6_+_167584081 0.25 ENST00000366832.2
t-complex 10-like 2
chr18_-_500692 0.25 ENST00000400256.3
collectin sub-family member 12
chr9_-_16728161 0.25 ENST00000603713.1
ENST00000603313.1
basonuclin 2
chr9_+_44867571 0.25 ENST00000377548.2
RP11-160N1.10
chr12_-_23737534 0.24 ENST00000396007.2
SRY (sex determining region Y)-box 5

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.6 1.8 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.5 1.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.4 0.4 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.4 1.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.3 0.9 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 3.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.4 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.8 GO:0060005 vestibular reflex(GO:0060005)
0.1 3.7 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.8 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.1 0.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.7 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 2.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 2.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 1.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.7 GO:0072378 blood coagulation, intrinsic pathway(GO:0007597) blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.3 GO:2000854 positive regulation of corticosterone secretion(GO:2000854)
0.1 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 1.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 1.0 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 1.5 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 1.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.6 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.3 GO:1902725 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.6 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0060585 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.9 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.5 GO:0007625 grooming behavior(GO:0007625)
0.1 1.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.3 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.2 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 1.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.4 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.3 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.6 GO:0072257 negative regulation of catenin import into nucleus(GO:0035414) metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.3 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 1.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.0 5.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 2.3 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 2.8 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 1.1 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 1.6 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 2.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0007595 lactation(GO:0007595)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.2 0.6 GO:0043257 laminin-8 complex(GO:0043257)
0.2 1.2 GO:0014802 terminal cisterna(GO:0014802)
0.1 1.4 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.7 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0034686 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.1 2.5 GO:0032433 filopodium tip(GO:0032433)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.6 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.4 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0071547 piP-body(GO:0071547)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0043034 costamere(GO:0043034)
0.0 3.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.7 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.4 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.9 2.6 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.4 1.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 3.9 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 0.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.2 GO:0005148 prolactin receptor binding(GO:0005148)
0.1 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.5 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 8.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 2.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 4.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport