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Results for MEIS3_TGIF2LX

Z-value: 1.15

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Transcription factors associated with MEIS3_TGIF2LX

Gene Symbol Gene ID Gene Info
ENSG00000105419.13 Meis homeobox 3
ENSG00000153779.8 TGFB induced factor homeobox 2 like X-linked

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2LXhg19_v2_chrX_+_89176881_891769550.154.0e-01Click!
MEIS3hg19_v2_chr19_-_47922373_47922572-0.134.7e-01Click!

Activity profile of MEIS3_TGIF2LX motif

Sorted Z-values of MEIS3_TGIF2LX motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_107590383 5.91 ENST00000525934.1
ENST00000531293.1
sarcolipin
chr8_+_86351056 4.58 ENST00000285381.2
carbonic anhydrase III, muscle specific
chr19_-_45826125 4.37 ENST00000221476.3
creatine kinase, muscle
chr17_+_41003166 4.12 ENST00000308423.2
amine oxidase, copper containing 3
chr3_+_8775466 3.91 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr11_+_18287721 3.84 ENST00000356524.4
serum amyloid A1
chr11_+_18287801 3.81 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr12_-_54978086 3.63 ENST00000553113.1
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr17_-_1395954 3.02 ENST00000359786.5
myosin IC
chr16_+_1290694 2.63 ENST00000338844.3
tryptase alpha/beta 1
chr16_+_1290725 2.63 ENST00000461509.2
tryptase alpha/beta 1
chr11_+_117947782 2.51 ENST00000522307.1
ENST00000523251.1
ENST00000437212.3
ENST00000522824.1
ENST00000522151.1
transmembrane protease, serine 4
chr1_-_47655686 2.45 ENST00000294338.2
PDZK1 interacting protein 1
chr5_+_115298165 2.32 ENST00000357872.4
Aminopeptidase Q
chr1_-_201081579 2.26 ENST00000367338.3
ENST00000362061.3
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr11_+_1942580 2.18 ENST00000381558.1
troponin T type 3 (skeletal, fast)
chr16_+_1306060 1.99 ENST00000397534.2
tryptase delta 1
chr9_-_22009297 1.96 ENST00000276925.6
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_+_120110863 1.90 ENST00000543440.2
POU class 2 homeobox 3
chr10_-_5060147 1.85 ENST00000604507.1
aldo-keto reductase family 1, member C2
chrX_+_135618258 1.85 ENST00000440515.1
ENST00000456412.1
vestigial like 1 (Drosophila)
chr10_-_5060201 1.80 ENST00000407674.1
aldo-keto reductase family 1, member C2
chr9_-_22009241 1.78 ENST00000380142.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr2_-_42160486 1.78 ENST00000427054.1
AC104654.2
chr11_-_2170786 1.76 ENST00000300632.5
insulin-like growth factor 2 (somatomedin A)
chr5_+_115298145 1.69 ENST00000395528.2
Aminopeptidase Q
chr11_-_119187826 1.67 ENST00000264036.4
melanoma cell adhesion molecule
chr16_+_66410244 1.55 ENST00000562048.1
ENST00000568155.2
cadherin 5, type 2 (vascular endothelium)
chr17_-_39781054 1.51 ENST00000463128.1
keratin 17
chr17_+_37782955 1.48 ENST00000580825.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_+_154801678 1.45 ENST00000462837.1
membrane metallo-endopeptidase
chr16_+_1306093 1.42 ENST00000211076.3
tryptase delta 1
chr8_+_67039278 1.42 ENST00000276573.7
ENST00000350034.4
tripartite motif containing 55
chr11_-_76381029 1.41 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr17_-_39780634 1.40 ENST00000577817.2
keratin 17
chr6_-_150219232 1.40 ENST00000531073.1
retinoic acid early transcript 1E
chr10_+_99349450 1.40 ENST00000370640.3
chromosome 10 open reading frame 62
chr9_+_34990219 1.35 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_-_7661623 1.35 ENST00000298441.6
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr4_-_187517928 1.33 ENST00000512772.1
FAT atypical cadherin 1
chr6_+_160769300 1.30 ENST00000275300.2
solute carrier family 22 (organic cation transporter), member 3
chr8_+_67039131 1.27 ENST00000315962.4
ENST00000353317.5
tripartite motif containing 55
chr5_-_42887494 1.26 ENST00000514218.1
selenoprotein P, plasma, 1
chr6_+_160769399 1.22 ENST00000392145.1
solute carrier family 22 (organic cation transporter), member 3
chr21_-_43735446 1.21 ENST00000398431.2
trefoil factor 3 (intestinal)
chr2_+_97203082 1.20 ENST00000454558.2
AT rich interactive domain 5A (MRF1-like)
chr18_+_7231123 1.19 ENST00000383467.2
leucine rich repeat containing 30
chr1_+_46379254 1.19 ENST00000372008.2
microtubule associated serine/threonine kinase 2
chr5_-_44388899 1.16 ENST00000264664.4
fibroblast growth factor 10
chr2_+_97202480 1.14 ENST00000357485.3
AT rich interactive domain 5A (MRF1-like)
chr10_+_50507232 1.11 ENST00000374144.3
chromosome 10 open reading frame 71
chr19_-_51529849 1.10 ENST00000600362.1
ENST00000453757.3
ENST00000601671.1
kallikrein-related peptidase 11
chr1_-_153517473 1.09 ENST00000368715.1
S100 calcium binding protein A4
chr10_+_123970670 1.07 ENST00000496913.2
transforming, acidic coiled-coil containing protein 2
chr17_-_34122596 1.07 ENST00000250144.8
matrix metallopeptidase 28
chr17_-_39780819 1.06 ENST00000311208.8
keratin 17
chr19_-_51530916 1.05 ENST00000594768.1
kallikrein-related peptidase 11
chr4_-_18023350 1.05 ENST00000539056.1
ENST00000382226.5
ENST00000326877.4
ligand dependent nuclear receptor corepressor-like
chr12_+_95611536 1.05 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chr1_+_86934526 1.05 ENST00000394711.1
chloride channel accessory 1
chr11_+_827553 1.04 ENST00000528542.2
ENST00000450448.1
EF-hand calcium binding domain 4A
chr18_+_3449330 1.03 ENST00000549253.1
TGFB-induced factor homeobox 1
chr13_+_78109884 1.02 ENST00000377246.3
ENST00000349847.3
sciellin
chr12_-_53298841 1.01 ENST00000293308.6
keratin 8
chr19_-_51531272 1.01 ENST00000319720.7
kallikrein-related peptidase 11
chr16_-_2004683 0.99 ENST00000268661.7
ribosomal protein L3-like
chr12_+_95611516 0.98 ENST00000436874.1
vezatin, adherens junctions transmembrane protein
chr19_-_51531210 0.97 ENST00000391804.3
kallikrein-related peptidase 11
chr13_+_78109804 0.96 ENST00000535157.1
sciellin
chr9_-_86432547 0.96 ENST00000376365.3
ENST00000376371.2
G kinase anchoring protein 1
chr17_-_19648916 0.94 ENST00000444455.1
ENST00000439102.2
aldehyde dehydrogenase 3 family, member A1
chr2_-_218770168 0.91 ENST00000413554.1
tensin 1
chr1_-_155162658 0.90 ENST00000368389.2
ENST00000368396.4
ENST00000343256.5
ENST00000342482.4
ENST00000368398.3
ENST00000368390.3
ENST00000337604.5
ENST00000368392.3
ENST00000438413.1
ENST00000368393.3
ENST00000457295.2
ENST00000338684.5
ENST00000368395.1
mucin 1, cell surface associated
chr6_+_53948328 0.89 ENST00000370876.2
muscular LMNA-interacting protein
chr3_+_29322437 0.87 ENST00000434693.2
RNA binding motif, single stranded interacting protein 3
chr12_+_95611569 0.86 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
vezatin, adherens junctions transmembrane protein
chr3_-_149093499 0.85 ENST00000472441.1
transmembrane 4 L six family member 1
chr21_+_30502806 0.84 ENST00000399928.1
ENST00000399926.1
MAP3K7 C-terminal like
chr3_-_49726486 0.81 ENST00000449682.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_+_86511549 0.81 ENST00000533902.2
protease, serine, 23
chr6_+_53948221 0.80 ENST00000460844.2
muscular LMNA-interacting protein
chr18_-_52989525 0.79 ENST00000457482.3
transcription factor 4
chr7_-_141957847 0.77 ENST00000552471.1
ENST00000547058.2
protease, serine, 58
chr14_-_67859422 0.76 ENST00000556532.1
pleckstrin 2
chr1_-_57285038 0.75 ENST00000343433.6
chromosome 1 open reading frame 168
chr22_+_21369316 0.74 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
purinergic receptor P2X, ligand-gated ion channel, 6
chr11_-_65325664 0.73 ENST00000301873.5
latent transforming growth factor beta binding protein 3
chr17_-_42345487 0.71 ENST00000262418.6
solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
chr17_+_37783197 0.69 ENST00000582680.1
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr20_-_57089934 0.69 ENST00000439429.1
ENST00000371149.3
adenomatosis polyposis coli down-regulated 1-like
chr4_-_184241927 0.69 ENST00000323319.5
claudin 22
chr19_-_9092018 0.68 ENST00000397910.4
mucin 16, cell surface associated
chr12_+_104458235 0.67 ENST00000229330.4
host cell factor C2
chr17_+_7210294 0.67 ENST00000336452.7
eukaryotic translation initiation factor 5A
chr5_+_15500280 0.67 ENST00000504595.1
F-box and leucine-rich repeat protein 7
chr3_+_147795932 0.66 ENST00000490465.1
RP11-639B1.1
chr19_-_40791211 0.66 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr11_-_101000445 0.65 ENST00000534013.1
progesterone receptor
chr15_+_65337708 0.65 ENST00000334287.2
solute carrier family 51, beta subunit
chr18_+_3449821 0.64 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr1_+_228395755 0.64 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr17_+_37783170 0.63 ENST00000254079.4
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr3_+_49726932 0.63 ENST00000327697.6
ENST00000432042.1
ENST00000454491.1
ring finger protein 123
chr1_+_12704566 0.63 ENST00000376221.1
arylacetamide deacetylase-like 4
chr9_+_96026230 0.63 ENST00000448251.1
WNK lysine deficient protein kinase 2
chr3_-_133748913 0.62 ENST00000310926.4
solute carrier organic anion transporter family, member 2A1
chr7_-_156803329 0.62 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr5_-_58882219 0.61 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chr6_+_151662815 0.60 ENST00000359755.5
A kinase (PRKA) anchor protein 12
chr6_+_31887761 0.60 ENST00000413154.1
complement component 2
chrX_-_11445856 0.59 ENST00000380736.1
Rho GTPase activating protein 6
chr18_+_3449695 0.58 ENST00000343820.5
TGFB-induced factor homeobox 1
chr3_-_133748758 0.58 ENST00000493729.1
solute carrier organic anion transporter family, member 2A1
chr11_+_117947724 0.56 ENST00000534111.1
transmembrane protease, serine 4
chr5_+_155753745 0.56 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr7_+_116654958 0.56 ENST00000449366.1
suppression of tumorigenicity 7
chr14_+_24600484 0.56 ENST00000267426.5
fat storage-inducing transmembrane protein 1
chr9_-_33447584 0.55 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr22_+_39052632 0.55 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
chibby homolog 1 (Drosophila)
chr4_+_175839506 0.55 ENST00000505141.1
ENST00000359240.3
ENST00000445694.1
ADAM metallopeptidase domain 29
chr11_-_76381781 0.55 ENST00000260061.5
ENST00000404995.1
leucine rich repeat containing 32
chr2_-_241624705 0.54 ENST00000599492.1
HCG2013738; Uncharacterized protein
chr4_+_175839551 0.53 ENST00000404450.4
ENST00000514159.1
ADAM metallopeptidase domain 29
chr11_-_842509 0.52 ENST00000322028.4
polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
chr3_+_154801312 0.52 ENST00000497890.1
membrane metallo-endopeptidase
chr21_+_30503282 0.51 ENST00000399925.1
MAP3K7 C-terminal like
chr14_-_21502944 0.51 ENST00000382951.3
ribonuclease, RNase A family, 13 (non-active)
chrX_+_23925918 0.51 ENST00000379211.3
chromosome X open reading frame 58
chr9_-_140444814 0.50 ENST00000277531.4
patatin-like phospholipase domain containing 7
chr8_+_7345191 0.50 ENST00000335510.6
defensin, beta 105B
chr1_-_55341551 0.50 ENST00000537443.1
24-dehydrocholesterol reductase
chr5_-_16738451 0.50 ENST00000274203.9
ENST00000515803.1
myosin X
chr17_+_28256874 0.50 ENST00000541045.1
ENST00000536908.2
EF-hand calcium binding domain 5
chr2_+_233271546 0.50 ENST00000295453.3
alkaline phosphatase, placental-like 2
chr8_-_7681411 0.49 ENST00000334773.6
defensin, beta 105A
chr17_+_73089382 0.49 ENST00000538213.2
ENST00000584118.1
solute carrier family 16 (monocarboxylate transporter), member 5
chr17_-_76220740 0.47 ENST00000600484.1
Uncharacterized protein
chr1_-_153013588 0.46 ENST00000360379.3
small proline-rich protein 2D
chr1_+_82165350 0.46 ENST00000359929.3
latrophilin 2
chr3_-_52719888 0.46 ENST00000458294.1
polybromo 1
chr19_+_6361754 0.45 ENST00000597326.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chrX_+_17755563 0.45 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
sex comb on midleg-like 1 (Drosophila)
chr8_+_95653840 0.44 ENST00000520385.1
epithelial splicing regulatory protein 1
chr10_-_79398127 0.43 ENST00000372443.1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_67360712 0.43 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
leucine rich repeat containing 36
chr19_+_6361841 0.42 ENST00000596605.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr14_-_54418598 0.42 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chrX_-_117250740 0.42 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
kelch-like family member 13
chr2_+_232457569 0.42 ENST00000313965.2
chromosome 2 open reading frame 57
chr6_+_112375275 0.42 ENST00000368666.2
ENST00000604763.1
ENST00000230529.5
WNT1 inducible signaling pathway protein 3
chr3_-_12883026 0.41 ENST00000396953.2
ENST00000457131.1
ENST00000435983.1
ENST00000273223.6
ENST00000396957.1
ENST00000429711.2
ribosomal protein L32
chrX_+_17755696 0.41 ENST00000419185.1
sex comb on midleg-like 1 (Drosophila)
chr19_+_6361795 0.41 ENST00000596149.1
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr6_+_34204642 0.41 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr19_+_1000418 0.40 ENST00000234389.3
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr11_+_86511569 0.40 ENST00000441050.1
protease, serine, 23
chr6_+_50061315 0.40 ENST00000415106.1
RP11-397G17.1
chr10_+_104503727 0.40 ENST00000448841.1
WW domain binding protein 1-like
chr19_-_40791302 0.39 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr1_+_145549203 0.39 ENST00000355594.4
ENST00000544626.1
ankyrin repeat domain 35
chr2_-_175202151 0.39 ENST00000595354.1
Uncharacterized protein FLJ46347
chr19_+_48337701 0.38 ENST00000535362.1
tetra-peptide repeat homeobox 2 pseudogene
chr6_+_50681541 0.37 ENST00000008391.3
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr22_+_44319648 0.37 ENST00000423180.2
patatin-like phospholipase domain containing 3
chr19_+_5455421 0.37 ENST00000222033.4
zinc and ring finger 4
chr2_+_26785409 0.37 ENST00000329615.3
ENST00000409392.1
chromosome 2 open reading frame 70
chr19_+_18530146 0.36 ENST00000348495.6
ENST00000270061.7
single stranded DNA binding protein 4
chrX_+_47420516 0.36 ENST00000377045.4
ENST00000290277.6
ENST00000377039.2
v-raf murine sarcoma 3611 viral oncogene homolog
chr14_+_100789669 0.36 ENST00000361529.3
ENST00000557052.1
solute carrier family 25, member 47
chr4_+_175839517 0.35 ENST00000502940.1
ENST00000502305.1
ADAM metallopeptidase domain 29
chr9_-_130667592 0.34 ENST00000447681.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr10_-_104597286 0.33 ENST00000369887.3
cytochrome P450, family 17, subfamily A, polypeptide 1
chr2_+_162087577 0.33 ENST00000439442.1
TRAF family member-associated NFKB activator
chr17_-_79533608 0.33 ENST00000572760.1
ENST00000573876.1
nuclear protein localization 4 homolog (S. cerevisiae)
chr7_+_76139833 0.33 ENST00000257632.5
uroplakin 3B
chr7_+_76139925 0.32 ENST00000394849.1
uroplakin 3B
chr3_-_122512619 0.32 ENST00000383659.1
ENST00000306103.2
HSPB (heat shock 27kDa) associated protein 1
chr11_+_60524426 0.32 ENST00000528170.1
ENST00000337911.4
ENST00000405633.3
membrane-spanning 4-domains, subfamily A, member 15
chr7_-_99332719 0.32 ENST00000336374.2
cytochrome P450, family 3, subfamily A, polypeptide 7
chrY_-_2655644 0.31 ENST00000525526.2
ENST00000534739.2
ENST00000383070.1
sex determining region Y
chr19_+_999601 0.30 ENST00000594393.1
Uncharacterized protein
chr2_-_3595547 0.29 ENST00000438485.1
Uncharacterized protein
chr1_-_32264250 0.29 ENST00000528579.1
SPOC domain containing 1
chr11_+_47608198 0.29 ENST00000356737.2
ENST00000538490.1
family with sequence similarity 180, member B
chr17_+_48172639 0.28 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr11_+_45868957 0.28 ENST00000443527.2
cryptochrome 2 (photolyase-like)
chr4_-_135248604 0.27 ENST00000515491.1
ENST00000504728.1
ENST00000506638.1
RP11-400D2.2
chr16_+_20817953 0.27 ENST00000568647.1
Putative RNA exonuclease NEF-sp
chr19_+_53517174 0.27 ENST00000602168.1
endogenous retrovirus group V, member 1
chr3_+_52719936 0.26 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr2_+_242089833 0.26 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
protein phosphatase 1, regulatory subunit 7
chr12_-_123215306 0.26 ENST00000356987.2
ENST00000436083.2
hydroxycarboxylic acid receptor 1
chr11_+_64073699 0.26 ENST00000405666.1
ENST00000468670.1
estrogen-related receptor alpha
chr1_+_210406121 0.25 ENST00000367012.3
SERTA domain containing 4
chr11_-_615570 0.25 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr19_-_10227503 0.25 ENST00000593054.1
eukaryotic translation initiation factor 3, subunit G
chr19_+_18530184 0.25 ENST00000601357.2
single stranded DNA binding protein 4
chr2_-_65593784 0.25 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr11_-_18956556 0.25 ENST00000302797.3
MAS-related GPR, member X1
chr7_-_144100786 0.25 ENST00000223140.5
NOBOX oogenesis homeobox

Network of associatons between targets according to the STRING database.

First level regulatory network of MEIS3_TGIF2LX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
1.4 4.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.6 3.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.5 3.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 3.6 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 1.2 GO:0060661 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) secretion by lung epithelial cell involved in lung growth(GO:0061033) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.3 4.4 GO:0006600 creatine metabolic process(GO:0006600)
0.3 2.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 2.0 GO:0046449 creatinine metabolic process(GO:0046449)
0.2 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 0.7 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2 2.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 1.8 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2 4.0 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.2 7.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.2 1.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 1.6 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 1.7 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.7 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 2.5 GO:0051608 histamine transport(GO:0051608)
0.1 2.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.4 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.3 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.6 GO:0070295 renal water absorption(GO:0070295)
0.1 3.7 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.3 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.1 0.4 GO:0072096 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.5 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.5 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 4.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 1.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.1 0.6 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.3 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.2 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.2 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.3 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.6 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.6 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.4 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.2 GO:2000027 regulation of organ morphogenesis(GO:2000027)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 2.2 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 2.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.6 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 5.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 1.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.1 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.0 0.3 GO:2000018 regulation of male gonad development(GO:2000018) positive regulation of male gonad development(GO:2000020)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.0 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.6 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.9 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.4 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.4 GO:0015879 carnitine transport(GO:0015879)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0045160 myosin I complex(GO:0045160)
0.3 1.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.2 7.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 2.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 5.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 5.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.9 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.7 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 2.5 GO:0001533 cornified envelope(GO:0001533)
0.0 4.2 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.5 GO:0031527 filopodium membrane(GO:0031527) filopodium tip(GO:0032433)
0.0 4.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.6 GO:0005884 actin filament(GO:0005884)
0.0 1.8 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0034709 methylosome(GO:0034709)
0.0 2.0 GO:0005903 brush border(GO:0005903)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.6 2.8 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 2.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.5 3.6 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.5 4.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.4 4.4 GO:0004111 creatine kinase activity(GO:0004111)
0.4 1.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 3.9 GO:0071253 connexin binding(GO:0071253)
0.3 3.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 4.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 2.5 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.2 3.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 3.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 8.1 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 1.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.9 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 2.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.7 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 2.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 2.3 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 20.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 7.0 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 5.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.5 GO:0009881 photoreceptor activity(GO:0009881)
0.0 2.9 GO:0017022 myosin binding(GO:0017022)
0.0 0.5 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 2.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 2.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 7.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 3.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 6.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 4.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 4.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 7.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 5.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 6.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 3.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 2.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex