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Illumina Body Map 2

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Results for MSX2

Z-value: 1.01

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Transcription factors associated with MSX2

Gene Symbol Gene ID Gene Info
MSX2
ENSG00000120149.7 msh homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSX2hg19_v2_chr5_+_174151536_1741516100.105.9e-01Click!

Activity profile of MSX2 motif

Sorted Z-values of MSX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_15332665 4.34 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chrX_-_21676442 3.60 ENST00000379499.2
KLHL34
kelch-like family member 34
chr8_+_1993152 3.49 ENST00000262113.4
MYOM2
myomesin 2
chr6_-_139613269 3.24 ENST00000358430.3
TXLNB
taxilin beta
chr14_+_32798462 3.21 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr8_+_1993173 3.16 ENST00000523438.1
MYOM2
myomesin 2
chr14_+_32798547 3.15 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr6_+_53948221 2.91 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chrX_+_130192318 2.73 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr6_+_53948328 2.66 ENST00000370876.2
MLIP
muscular LMNA-interacting protein
chr4_-_109684120 2.53 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr22_+_17956618 2.45 ENST00000262608.8
CECR2
cat eye syndrome chromosome region, candidate 2
chr10_-_72142345 1.79 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20
leucine rich repeat containing 20
chr11_-_13517565 1.58 ENST00000282091.1
ENST00000529816.1
PTH
parathyroid hormone
chr1_+_152943122 1.40 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr15_+_41245160 1.28 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr1_+_202317855 1.26 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr17_-_10372875 1.20 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr9_+_124329336 1.16 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr7_-_88425025 1.16 ENST00000297203.2
C7orf62
chromosome 7 open reading frame 62
chr5_+_95998070 1.14 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr7_-_100183742 1.09 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr20_+_56964169 1.09 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr1_-_151762943 1.06 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH
tudor and KH domain containing
chr19_+_46236509 1.01 ENST00000457052.2
AC074212.3
Uncharacterized protein
chr6_+_78400375 1.00 ENST00000602452.2
MEI4
meiosis-specific 4 homolog (S. cerevisiae)
chr13_-_103389159 0.97 ENST00000322527.2
CCDC168
coiled-coil domain containing 168
chr5_-_132200477 0.97 ENST00000296875.2
GDF9
growth differentiation factor 9
chr5_+_140557371 0.96 ENST00000239444.2
PCDHB8
protocadherin beta 8
chr8_+_9413410 0.95 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_+_34204642 0.95 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr1_-_151762900 0.94 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr3_-_114866084 0.92 ENST00000357258.3
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_46996424 0.92 ENST00000264318.3
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr4_-_138453606 0.90 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18
protocadherin 18
chr18_+_5748793 0.85 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1
chr6_-_167040731 0.85 ENST00000265678.4
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_-_88449771 0.84 ENST00000535835.1
SPARCL1
SPARC-like 1 (hevin)
chr17_+_12569306 0.80 ENST00000425538.1
MYOCD
myocardin
chr4_-_69536346 0.80 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr1_-_21377383 0.79 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr5_+_95997918 0.79 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST
calpastatin
chr16_-_52061283 0.79 ENST00000566314.1
C16orf97
chromosome 16 open reading frame 97
chr7_+_100183927 0.78 ENST00000241071.6
ENST00000360609.2
FBXO24
F-box protein 24
chr1_-_232651312 0.77 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr1_-_36916066 0.77 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr5_+_95997885 0.75 ENST00000511097.2
CAST
calpastatin
chr18_-_48346298 0.75 ENST00000398439.3
MRO
maestro
chr1_-_94050668 0.75 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr20_+_31805131 0.73 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr1_-_36916011 0.72 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr6_-_167040693 0.72 ENST00000366863.2
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_36915880 0.69 ENST00000445843.3
OSCP1
organic solute carrier partner 1
chr3_+_140396881 0.69 ENST00000286349.3
TRIM42
tripartite motif containing 42
chr1_-_8877692 0.68 ENST00000400908.2
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr18_+_63273310 0.68 ENST00000579862.1
RP11-775G23.1
RP11-775G23.1
chrX_+_89176881 0.67 ENST00000283891.5
ENST00000561129.2
TGIF2LX
TGFB-induced factor homeobox 2-like, X-linked
chr1_+_202317815 0.66 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr20_+_56964253 0.66 ENST00000395802.3
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr12_-_10955226 0.66 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr19_+_42817450 0.65 ENST00000301204.3
TMEM145
transmembrane protein 145
chr2_-_200335983 0.64 ENST00000457245.1
SATB2
SATB homeobox 2
chr14_-_23504337 0.61 ENST00000361611.6
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chr3_-_164796269 0.61 ENST00000264382.3
SI
sucrase-isomaltase (alpha-glucosidase)
chr6_+_25652432 0.60 ENST00000377961.2
SCGN
secretagogin, EF-hand calcium binding protein
chr7_+_130794846 0.60 ENST00000421797.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr8_+_92261516 0.59 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr20_-_50418947 0.59 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr8_-_117886563 0.59 ENST00000519837.1
ENST00000522699.1
RAD21
RAD21 homolog (S. pombe)
chr4_-_138453559 0.58 ENST00000511115.1
PCDH18
protocadherin 18
chr10_+_99205959 0.58 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr5_+_31532373 0.56 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr20_-_50419055 0.56 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr14_-_23504432 0.55 ENST00000425762.2
PSMB5
proteasome (prosome, macropain) subunit, beta type, 5
chrX_+_77154935 0.55 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr11_-_123814580 0.55 ENST00000321252.2
OR6T1
olfactory receptor, family 6, subfamily T, member 1
chr16_+_69345243 0.54 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr19_-_47137942 0.51 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr7_+_130794878 0.50 ENST00000416992.2
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr9_-_95056010 0.50 ENST00000443024.2
IARS
isoleucyl-tRNA synthetase
chr4_-_46126093 0.49 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr17_-_12920907 0.49 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
ELAC2
elaC ribonuclease Z 2
chr1_+_244515930 0.49 ENST00000366537.1
ENST00000308105.4
C1orf100
chromosome 1 open reading frame 100
chr6_+_25652501 0.49 ENST00000334979.6
SCGN
secretagogin, EF-hand calcium binding protein
chrX_-_139587225 0.49 ENST00000370536.2
SOX3
SRY (sex determining region Y)-box 3
chr19_-_19249255 0.48 ENST00000587583.2
ENST00000450333.2
ENST00000587096.1
ENST00000162044.9
ENST00000592369.1
ENST00000587915.1
TMEM161A
transmembrane protein 161A
chr5_-_31532160 0.48 ENST00000511367.2
ENST00000513349.1
DROSHA
drosha, ribonuclease type III
chr8_-_117886612 0.48 ENST00000520992.1
RAD21
RAD21 homolog (S. pombe)
chr6_-_111927449 0.48 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr17_-_43045439 0.47 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chr12_+_64798826 0.47 ENST00000540203.1
XPOT
exportin, tRNA
chr3_+_147795932 0.46 ENST00000490465.1
RP11-639B1.1
RP11-639B1.1
chr12_-_95397442 0.45 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr1_+_151735431 0.44 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr20_-_50418972 0.44 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr1_-_190446759 0.43 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr11_-_40315640 0.42 ENST00000278198.2
LRRC4C
leucine rich repeat containing 4C
chr19_-_46088068 0.40 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr6_-_111927062 0.40 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr5_+_140797296 0.39 ENST00000398594.2
PCDHGB7
protocadherin gamma subfamily B, 7
chr2_-_73460334 0.39 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr18_+_39535239 0.39 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr14_-_36990061 0.38 ENST00000546983.1
NKX2-1
NK2 homeobox 1
chr7_+_91570165 0.36 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9
A kinase (PRKA) anchor protein 9
chr8_-_12612962 0.36 ENST00000398246.3
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr11_-_124190184 0.35 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr9_-_107299137 0.35 ENST00000374781.2
OR13C3
olfactory receptor, family 13, subfamily C, member 3
chr2_+_172864490 0.35 ENST00000315796.4
METAP1D
methionyl aminopeptidase type 1D (mitochondrial)
chr20_-_54967187 0.35 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA
aurora kinase A
chr12_-_57039739 0.32 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr1_-_197115818 0.32 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr2_+_187371440 0.32 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr11_-_71823796 0.31 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15
anaphase promoting complex subunit 15
chr12_+_28410128 0.31 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr1_-_228613026 0.30 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr17_+_44679808 0.30 ENST00000571172.1
NSF
N-ethylmaleimide-sensitive factor
chr5_-_31532238 0.30 ENST00000507438.1
DROSHA
drosha, ribonuclease type III
chr11_-_71823715 0.29 ENST00000545944.1
ENST00000502597.2
ANAPC15
anaphase promoting complex subunit 15
chr7_-_99716940 0.29 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr19_+_17378278 0.28 ENST00000596335.1
ENST00000601436.1
ENST00000595632.1
BABAM1
BRISC and BRCA1 A complex member 1
chr10_+_99205894 0.28 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr10_-_99205607 0.27 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
EXOSC1
exosome component 1
chr19_+_17378159 0.27 ENST00000598188.1
ENST00000359435.4
ENST00000599474.1
ENST00000599057.1
ENST00000601043.1
ENST00000447614.2
BABAM1
BRISC and BRCA1 A complex member 1
chr11_+_17298342 0.27 ENST00000530964.1
NUCB2
nucleobindin 2
chr10_-_15762124 0.25 ENST00000378076.3
ITGA8
integrin, alpha 8
chr1_-_23694794 0.25 ENST00000374608.3
ZNF436
zinc finger protein 436
chr3_-_147997869 0.25 ENST00000460324.1
RP11-501O2.4
RP11-501O2.4
chr10_-_105110831 0.25 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr7_-_99716952 0.24 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_71587669 0.23 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr3_-_141747950 0.22 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr10_-_105110890 0.21 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr17_-_80250663 0.20 ENST00000581489.1
RP13-516M14.4
RP13-516M14.4
chr7_-_99717463 0.19 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_-_46716647 0.18 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chrX_-_69269788 0.18 ENST00000276101.3
AWAT2
acyl-CoA wax alcohol acyltransferase 2
chr15_+_80351910 0.18 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr19_+_42817527 0.17 ENST00000598766.1
TMEM145
transmembrane protein 145
chr1_+_198985262 0.17 ENST00000432488.1
RP11-16L9.4
RP11-16L9.4
chr17_+_67759813 0.16 ENST00000587241.1
AC003051.1
AC003051.1
chr18_+_39535152 0.16 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr11_+_17298543 0.16 ENST00000533926.1
NUCB2
nucleobindin 2
chr5_+_162864575 0.15 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr12_+_9102632 0.14 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr3_+_186353756 0.14 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr19_-_10121144 0.13 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr12_+_52695617 0.12 ENST00000293525.5
KRT86
keratin 86
chr1_-_151431909 0.10 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr11_-_121986923 0.09 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr1_-_151431674 0.09 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr9_-_5339873 0.08 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chrX_+_113818545 0.08 ENST00000371951.1
ENST00000276198.1
ENST00000371950.3
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
chr17_-_38956205 0.07 ENST00000306658.7
KRT28
keratin 28
chr1_+_211813019 0.07 ENST00000430123.1
RP11-354K1.1
RP11-354K1.1
chr1_-_151431647 0.07 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr12_-_120315074 0.07 ENST00000261833.7
ENST00000392521.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr11_-_58207646 0.07 ENST00000302572.2
OR5B12
olfactory receptor, family 5, subfamily B, member 12
chr11_-_71823266 0.05 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15
anaphase promoting complex subunit 15
chr12_+_117099342 0.04 ENST00000546835.1
RP11-497G19.1
RP11-497G19.1
chr7_-_56174161 0.04 ENST00000395422.3
CHCHD2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr11_+_17298522 0.03 ENST00000529313.1
NUCB2
nucleobindin 2
chr15_-_98417780 0.02 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr3_-_11685345 0.01 ENST00000430365.2
VGLL4
vestigial like 4 (Drosophila)
chr21_-_32253874 0.01 ENST00000332378.4
KRTAP11-1
keratin associated protein 11-1
chr20_+_54967409 0.00 ENST00000415828.1
ENST00000217109.4
ENST00000428552.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
chr4_-_19458597 0.00 ENST00000505347.1
RP11-3J1.1
RP11-3J1.1
chr3_-_112127981 0.00 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr20_+_54967663 0.00 ENST00000452950.1
CSTF1
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of MSX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.7 6.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.5 1.6 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 1.0 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.2 1.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 1.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 1.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.9 GO:2001023 regulation of response to drug(GO:2001023)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 1.3 GO:0019236 response to pheromone(GO:0019236)
0.2 0.5 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.2 0.5 GO:0099558 maintenance of synapse structure(GO:0099558)
0.2 1.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.7 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 2.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.5 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.1 2.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 2.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 2.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.1 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.7 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.7 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.0 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.5 GO:0007530 sex determination(GO:0007530)
0.0 1.2 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0044301 climbing fiber(GO:0044301)
0.4 6.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.3 0.8 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 7.9 GO:0032982 myosin filament(GO:0032982)
0.2 2.0 GO:0071547 piP-body(GO:0071547)
0.1 2.5 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.5 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.1 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 0.3 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.0 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 2.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 6.3 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0090543 ESCRT III complex(GO:0000815) Flemming body(GO:0090543)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 3.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 1.4 GO:0001533 cornified envelope(GO:0001533)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.6 1.7 GO:0033149 FFAT motif binding(GO:0033149)
0.3 1.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 6.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 2.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 6.7 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 1.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.6 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.8 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.5 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.5 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.9 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 1.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.7 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.6 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 1.2 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.8 GO:0000339 RNA cap binding(GO:0000339)
0.0 3.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 3.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport