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Illumina Body Map 2
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Results for MYB
Z-value: 3.66
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Transcription factors associated with MYB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYB | hg19_v2_chr6_+_135502501_135502652 | 0.31 | 8.4e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 77.7 | GO:0007286 | spermatid development(GO:0007286) |
| 0.1 | 42.7 | GO:0007283 | spermatogenesis(GO:0007283) |
| 1.6 | 42.2 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 1.1 | 20.8 | GO:0007342 | fusion of sperm to egg plasma membrane(GO:0007342) |
| 0.6 | 19.3 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 4.2 | 12.7 | GO:0051039 | histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039) |
| 0.1 | 12.5 | GO:1904029 | regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.2 | 11.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 2.9 | 11.7 | GO:0000711 | meiotic DNA repair synthesis(GO:0000711) |
| 0.3 | 11.0 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 28.4 | GO:0000795 | synaptonemal complex(GO:0000795) |
| 0.2 | 22.2 | GO:0031514 | motile cilium(GO:0031514) |
| 0.2 | 21.8 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.2 | 17.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.7 | 17.6 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 1.1 | 17.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 16.4 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.4 | 14.8 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.9 | 14.0 | GO:0001520 | outer dense fiber(GO:0001520) |
| 0.1 | 12.3 | GO:0036064 | ciliary basal body(GO:0036064) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 30.5 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 1.4 | 27.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.5 | 25.8 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 23.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 23.1 | GO:0000987 | core promoter proximal region sequence-specific DNA binding(GO:0000987) |
| 0.5 | 18.6 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.4 | 14.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 13.1 | GO:0008270 | zinc ion binding(GO:0008270) |
| 0.2 | 13.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.2 | 11.9 | GO:0031369 | translation initiation factor binding(GO:0031369) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 33.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.3 | 19.9 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.2 | 16.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 11.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 7.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 5.4 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 5.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 3.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 3.8 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 3.6 | PID P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 25.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 25.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.3 | 10.6 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.0 | 9.3 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.4 | 7.6 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.5 | 7.1 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.2 | 7.0 | REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.2 | 5.9 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.3 | 5.8 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 5.5 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |