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Illumina Body Map 2

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Results for NKX1-2_RAX

Z-value: 0.73

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Transcription factors associated with NKX1-2_RAX

Gene Symbol Gene ID Gene Info
ENSG00000229544.6 NK1 homeobox 2
ENSG00000134438.9 retina and anterior neural fold homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAXhg19_v2_chr18_-_56940611_56940660-0.261.6e-01Click!
NKX1-2hg19_v2_chr10_-_126138622_126138753-0.202.7e-01Click!

Activity profile of NKX1-2_RAX motif

Sorted Z-values of NKX1-2_RAX motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_114827818 2.84 ENST00000420625.2
plastin 3
chr12_-_22063787 2.61 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr10_-_4285835 2.59 ENST00000454470.1
long intergenic non-protein coding RNA 702
chrX_+_114827851 2.34 ENST00000539310.1
plastin 3
chr7_+_70597109 2.23 ENST00000333538.5
Williams-Beuren syndrome chromosome region 17
chr14_+_32798462 2.20 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr2_+_217524323 2.02 ENST00000456764.1
insulin-like growth factor binding protein 2, 36kDa
chr14_+_32798547 1.97 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr10_-_4285923 1.95 ENST00000418372.1
ENST00000608792.1
long intergenic non-protein coding RNA 702
chr1_+_201979645 1.77 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr10_+_6779326 1.73 ENST00000417112.1
RP11-554I8.2
chrX_+_43515467 1.72 ENST00000338702.3
ENST00000542639.1
monoamine oxidase A
chr6_+_53964336 1.67 ENST00000447836.2
ENST00000511678.1
muscular LMNA-interacting protein
chr3_-_151034734 1.66 ENST00000260843.4
G protein-coupled receptor 87
chr4_+_77356248 1.62 ENST00000296043.6
shroom family member 3
chr9_+_124329336 1.62 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2 interacting protein
chrX_-_21676442 1.54 ENST00000379499.2
kelch-like family member 34
chr13_-_36050819 1.46 ENST00000379919.4
mab-21-like 1 (C. elegans)
chr6_+_53883708 1.36 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr10_+_99205959 1.35 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr1_+_62439037 1.34 ENST00000545929.1
InaD-like (Drosophila)
chr3_-_120400960 1.33 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr10_+_24755416 1.22 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr9_-_95166976 1.20 ENST00000447356.1
osteoglycin
chr7_+_120628731 1.18 ENST00000310396.5
cadherin-like and PC-esterase domain containing 1
chr9_-_95166841 1.16 ENST00000262551.4
osteoglycin
chr5_-_35938674 1.16 ENST00000397366.1
ENST00000513623.1
ENST00000514524.1
ENST00000397367.2
calcyphosine-like
chr7_-_7575477 1.13 ENST00000399429.3
collagen, type XXVIII, alpha 1
chr1_-_151804314 1.12 ENST00000318247.6
RAR-related orphan receptor C
chr5_-_102898465 1.05 ENST00000507423.1
ENST00000230792.2
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr17_+_1666108 1.03 ENST00000570731.1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_99205894 0.96 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr6_-_94129244 0.96 ENST00000369303.4
ENST00000369297.1
EPH receptor A7
chr11_-_59383617 0.95 ENST00000263847.1
oxysterol binding protein
chr1_+_186265399 0.88 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr12_+_18414446 0.88 ENST00000433979.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
chr1_+_160370344 0.87 ENST00000368061.2
VANGL planar cell polarity protein 2
chr1_+_162336686 0.86 ENST00000420220.1
chromosome 1 open reading frame 226
chr11_+_71900572 0.86 ENST00000312293.4
folate receptor 1 (adult)
chr11_+_71900703 0.86 ENST00000393681.2
folate receptor 1 (adult)
chr7_-_107443652 0.84 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
solute carrier family 26 (anion exchanger), member 3
chr3_+_28390637 0.84 ENST00000420223.1
ENST00000383768.2
zinc finger, CW type with PWWP domain 2
chr11_+_112047087 0.82 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
beta-carotene oxygenase 2
chr12_+_7014126 0.82 ENST00000415834.1
ENST00000436789.1
leucine rich repeat containing 23
chr8_-_101571933 0.81 ENST00000520311.1
ankyrin repeat domain 46
chr12_+_7013897 0.77 ENST00000007969.8
ENST00000323702.5
leucine rich repeat containing 23
chr13_+_36050881 0.77 ENST00000537702.1
neurobeachin
chr3_-_105587879 0.76 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr8_+_92261516 0.74 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr16_+_82068585 0.72 ENST00000563491.1
hydroxysteroid (17-beta) dehydrogenase 2
chr2_-_198540751 0.72 ENST00000429081.1
raftlin family member 2
chr1_-_159832438 0.72 ENST00000368100.1
V-set and immunoglobulin domain containing 8
chr2_-_190446738 0.70 ENST00000427419.1
ENST00000455320.1
solute carrier family 40 (iron-regulated transporter), member 1
chr10_-_92681033 0.70 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr19_-_46285736 0.70 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr14_+_74034310 0.68 ENST00000538782.1
acyl-CoA thioesterase 2
chrX_+_130192318 0.67 ENST00000370922.1
Rho GTPase activating protein 36
chr3_+_183853052 0.65 ENST00000273783.3
ENST00000432569.1
ENST00000444495.1
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr12_+_7014064 0.64 ENST00000443597.2
leucine rich repeat containing 23
chr17_-_10372875 0.63 ENST00000255381.2
myosin, heavy chain 4, skeletal muscle
chr8_-_101571964 0.61 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ankyrin repeat domain 46
chr20_+_43990576 0.59 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr8_-_29605625 0.58 ENST00000506121.3
long intergenic non-protein coding RNA 589
chr4_-_74486217 0.58 ENST00000335049.5
ENST00000307439.5
Ras association (RalGDS/AF-6) domain family member 6
chr19_+_48949087 0.57 ENST00000598711.1
glutamate-rich WD repeat containing 1
chr1_-_159915386 0.56 ENST00000361509.3
ENST00000368094.1
immunoglobulin superfamily, member 9
chr11_+_22689648 0.53 ENST00000278187.3
growth arrest-specific 2
chr6_+_160542870 0.52 ENST00000324965.4
ENST00000457470.2
solute carrier family 22 (organic cation transporter), member 1
chr11_+_118398178 0.52 ENST00000302783.4
ENST00000539546.1
tetratricopeptide repeat domain 36
chr4_-_103749105 0.51 ENST00000394801.4
ENST00000394804.2
ubiquitin-conjugating enzyme E2D 3
chrX_+_135618258 0.51 ENST00000440515.1
ENST00000456412.1
vestigial like 1 (Drosophila)
chrX_+_19362011 0.51 ENST00000379806.5
ENST00000545074.1
ENST00000540249.1
ENST00000423505.1
ENST00000417819.1
ENST00000422285.2
ENST00000355808.5
ENST00000379805.3
pyruvate dehydrogenase (lipoamide) alpha 1
chr7_+_100770328 0.50 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr9_+_109685630 0.50 ENST00000451160.2
Uncharacterized protein
chr4_-_175041663 0.50 ENST00000503140.1
RP11-148L24.1
chr11_-_4389616 0.49 ENST00000408920.2
olfactory receptor, family 52, subfamily B, member 4
chr5_-_82969363 0.49 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr17_+_59489112 0.48 ENST00000335108.2
chromosome 17 open reading frame 82
chr6_-_167040731 0.48 ENST00000265678.4
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_167040693 0.48 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr4_-_103749313 0.47 ENST00000394803.5
ubiquitin-conjugating enzyme E2D 3
chr2_-_198540719 0.46 ENST00000295049.4
raftlin family member 2
chr3_+_195447738 0.46 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
mucin 20, cell surface associated
chr5_-_82969405 0.44 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr17_-_27418537 0.43 ENST00000408971.2
TGFB1-induced anti-apoptotic factor 1
chr2_-_220264703 0.43 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr5_+_63802109 0.43 ENST00000334025.2
regulator of G-protein signaling 7 binding protein
chr11_-_102651343 0.42 ENST00000279441.4
ENST00000539681.1
matrix metallopeptidase 10 (stromelysin 2)
chrM_+_9207 0.41 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr21_-_37914898 0.41 ENST00000399136.1
claudin 14
chr8_-_30670384 0.40 ENST00000221138.4
ENST00000518243.1
protein phosphatase 2, catalytic subunit, beta isozyme
chr4_-_103749179 0.39 ENST00000502690.1
ubiquitin-conjugating enzyme E2D 3
chr19_-_36001113 0.39 ENST00000434389.1
dermokine
chrX_+_77154935 0.38 ENST00000481445.1
cytochrome c oxidase subunit VIIb
chr7_+_138145076 0.38 ENST00000343526.4
tripartite motif containing 24
chr12_-_74686314 0.37 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
chr2_+_191221240 0.36 ENST00000409027.1
ENST00000458193.1
inositol polyphosphate-1-phosphatase
chr15_-_43882140 0.36 ENST00000429176.1
diphosphoinositol pentakisphosphate kinase 1
chr16_-_55866997 0.36 ENST00000360526.3
ENST00000361503.4
carboxylesterase 1
chr4_-_10686475 0.34 ENST00000226951.6
cytokine-dependent hematopoietic cell linker
chr11_-_123814580 0.34 ENST00000321252.2
olfactory receptor, family 6, subfamily T, member 1
chr19_+_37742773 0.34 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5
chr9_+_125133467 0.33 ENST00000426608.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr14_+_20187174 0.33 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chr12_+_8309630 0.33 ENST00000396570.3
zinc finger protein 705A
chr5_-_94890648 0.32 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr16_-_20702578 0.32 ENST00000307493.4
ENST00000219151.4
acyl-CoA synthetase medium-chain family member 1
chr1_+_43148059 0.30 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr11_-_63376013 0.30 ENST00000540943.1
phospholipase A2, group XVI
chr5_+_66300446 0.30 ENST00000261569.7
microtubule associated serine/threonine kinase family member 4
chr9_-_21239978 0.30 ENST00000380222.2
interferon, alpha 14
chr12_+_82347498 0.29 ENST00000550506.1
RP11-362A1.1
chr1_-_190446759 0.29 ENST00000367462.3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_-_103749205 0.29 ENST00000508249.1
ubiquitin-conjugating enzyme E2D 3
chr3_-_55539287 0.29 ENST00000472238.1
RP11-875H7.5
chr8_+_105602961 0.28 ENST00000521923.1
Uncharacterized protein
chr14_+_67831576 0.28 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr17_-_4938712 0.28 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr3_-_105588231 0.27 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr12_+_16500571 0.27 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr10_-_105845536 0.27 ENST00000393211.3
collagen, type XVII, alpha 1
chr4_-_103748880 0.27 ENST00000453744.2
ENST00000349311.8
ubiquitin-conjugating enzyme E2D 3
chr2_+_187371440 0.26 ENST00000445547.1
zinc finger CCCH-type containing 15
chr7_-_99716952 0.26 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr19_+_8740061 0.26 ENST00000593792.1
CTD-2586B10.1
chr2_-_239197201 0.25 ENST00000254658.3
period circadian clock 2
chr2_-_239197238 0.25 ENST00000254657.3
period circadian clock 2
chr1_+_158449668 0.25 ENST00000368152.1
olfactory receptor, family 10, subfamily R, member 2
chr6_-_111927449 0.24 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3 interacting protein 2
chr3_+_186353756 0.24 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
fetuin B
chr7_-_99716940 0.24 ENST00000440225.1
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr19_+_48949030 0.24 ENST00000253237.5
glutamate-rich WD repeat containing 1
chr4_-_74486109 0.23 ENST00000395777.2
Ras association (RalGDS/AF-6) domain family member 6
chr4_+_66536248 0.23 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
chr2_-_74619152 0.22 ENST00000440727.1
ENST00000409240.1
dynactin 1
chr12_+_32832203 0.22 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
dynamin 1-like
chr12_-_23737534 0.21 ENST00000396007.2
SRY (sex determining region Y)-box 5
chr6_-_82957433 0.20 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr12_+_64798826 0.20 ENST00000540203.1
exportin, tRNA
chr6_-_111927062 0.20 ENST00000359831.4
TRAF3 interacting protein 2
chr15_+_93447675 0.20 ENST00000536619.1
chromodomain helicase DNA binding protein 2
chr12_+_16500599 0.19 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr6_+_52442083 0.19 ENST00000606714.1
TRAM2 antisense RNA 1 (head to head)
chr4_-_141348789 0.19 ENST00000414773.1
calmegin
chr4_-_74486347 0.19 ENST00000342081.3
Ras association (RalGDS/AF-6) domain family member 6
chr16_-_48281444 0.19 ENST00000537808.1
ENST00000569991.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr7_-_99717463 0.19 ENST00000437822.2
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_+_135937365 0.18 ENST00000372080.4
ENST00000351304.7
carboxyl ester lipase
chr4_-_68829144 0.18 ENST00000508048.1
transmembrane protease, serine 11A
chr3_-_11685345 0.18 ENST00000430365.2
vestigial like 4 (Drosophila)
chr11_-_121986923 0.18 ENST00000560104.1
BH3-like motif containing, cell death inducer
chr11_+_29181503 0.17 ENST00000530960.1
RP11-466I1.1
chr1_-_28969517 0.16 ENST00000263974.4
ENST00000373824.4
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr4_+_31998999 0.16 ENST00000513211.1
RP11-734I18.1
chr6_+_30687978 0.16 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr20_-_1447547 0.16 ENST00000476071.1
NSFL1 (p97) cofactor (p47)
chr8_+_9413410 0.14 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_+_111748183 0.14 ENST00000422994.1
long intergenic non-protein coding RNA 368
chr9_+_34646651 0.14 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr11_-_74800799 0.14 ENST00000305159.3
olfactory receptor, family 2, subfamily AT, member 4
chr9_+_34646624 0.13 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr9_-_5339873 0.13 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr17_-_33390667 0.12 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr22_-_28490123 0.12 ENST00000442232.1
tetratricopeptide repeat domain 28
chr19_+_46236509 0.12 ENST00000457052.2
Uncharacterized protein
chr14_-_53258314 0.12 ENST00000216410.3
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr19_-_36822551 0.12 ENST00000591372.1
long intergenic non-protein coding RNA 665
chr12_-_10959892 0.12 ENST00000240615.2
taste receptor, type 2, member 8
chr10_-_99205607 0.11 ENST00000477692.2
ENST00000485122.2
ENST00000370886.5
ENST00000370885.4
ENST00000370902.3
ENST00000370884.5
exosome component 1
chr11_-_124981475 0.11 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr19_-_3985455 0.11 ENST00000309311.6
eukaryotic translation elongation factor 2
chr12_+_112279782 0.11 ENST00000550735.2
mitogen-activated protein kinase-activated protein kinase 5
chr16_-_48281305 0.11 ENST00000356608.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr4_-_68829226 0.11 ENST00000396188.2
transmembrane protease, serine 11A
chr20_-_1447467 0.11 ENST00000353088.2
ENST00000350991.4
NSFL1 (p97) cofactor (p47)
chr10_-_105845674 0.09 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr8_+_105235572 0.08 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr6_+_154360476 0.08 ENST00000428397.2
opioid receptor, mu 1
chr12_+_90674665 0.08 ENST00000549313.1
RP11-753N8.1
chr4_+_110736659 0.08 ENST00000394631.3
ENST00000226796.6
GAR1 ribonucleoprotein
chr19_-_36822595 0.08 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
long intergenic non-protein coding RNA 665
chr11_-_111741994 0.08 ENST00000398006.2
ALG9, alpha-1,2-mannosyltransferase
chr2_-_86422095 0.07 ENST00000254636.5
inner membrane protein, mitochondrial
chr21_-_35796241 0.07 ENST00000450895.1
AP000322.53
chr6_-_49937338 0.07 ENST00000398718.1
defensin, beta 113
chr2_-_74618907 0.06 ENST00000421392.1
ENST00000437375.1
dynactin 1
chr1_-_211307404 0.05 ENST00000367007.4
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr6_+_78400375 0.05 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr3_+_186560476 0.05 ENST00000320741.2
ENST00000444204.2
adiponectin, C1Q and collagen domain containing
chr1_+_28261492 0.05 ENST00000373894.3
sphingomyelin phosphodiesterase, acid-like 3B
chr8_+_29605825 0.05 ENST00000522158.1
AC145110.1
chr14_+_55493920 0.05 ENST00000395472.2
ENST00000555846.1
suppressor of cytokine signaling 4
chr3_+_186560462 0.05 ENST00000412955.2
adiponectin, C1Q and collagen domain containing
chr16_-_52061283 0.04 ENST00000566314.1
chromosome 16 open reading frame 97
chr8_-_94179079 0.03 ENST00000521906.1
chromosome 8 open reading frame 87
chr9_-_7961080 0.03 ENST00000435444.1
RP11-29B9.2
chr6_+_34204642 0.03 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
high mobility group AT-hook 1
chr17_-_40337470 0.03 ENST00000293330.1
hypocretin (orexin) neuropeptide precursor
chr19_+_36239576 0.03 ENST00000587751.1
lin-37 homolog (C. elegans)
chr1_+_192605252 0.03 ENST00000391995.2
ENST00000543215.1
regulator of G-protein signaling 13

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.5 4.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.4 1.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.3 1.6 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 0.9 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 0.8 GO:0042214 terpene metabolic process(GO:0042214)
0.2 0.7 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.2 5.2 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.5 GO:0001300 chronological cell aging(GO:0001300)
0.2 0.5 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.7 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 2.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 1.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 1.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.9 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.5 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 1.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.5 GO:0048241 epinephrine transport(GO:0048241)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 2.0 GO:0010226 response to lithium ion(GO:0010226)
0.1 1.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.1 2.3 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.0 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.4 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.7 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 2.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 1.1 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0097018 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.9 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 1.9 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.3 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1990032 parallel fiber(GO:1990032)
0.3 2.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 4.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.0 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.8 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 5.2 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 1.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 0.7 GO:0097689 iron channel activity(GO:0097689)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 4.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 1.7 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 2.1 GO:0008142 oxysterol binding(GO:0008142)
0.1 2.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.5 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.1 0.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.7 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.1 1.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 2.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.9 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 6.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression