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Illumina Body Map 2

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Results for NKX2-8

Z-value: 1.40

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_370518310.327.1e-02Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_106573756 4.84 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr14_-_107049312 4.79 ENST00000390627.2
IGHV3-53
immunoglobulin heavy variable 3-53
chr14_-_106552755 4.45 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr14_-_107199464 4.34 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr14_-_106518922 4.27 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr14_-_106692191 4.22 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr14_-_106586656 4.20 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr14_-_107131560 4.01 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr14_-_106994333 3.73 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr14_-_106622419 3.47 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr16_+_32063311 3.17 ENST00000426099.1
AC142381.1
AC142381.1
chr14_-_106791536 3.08 ENST00000390613.2
IGHV3-30
immunoglobulin heavy variable 3-30
chr14_-_107219365 3.03 ENST00000424969.2
IGHV3-74
immunoglobulin heavy variable 3-74
chr14_-_106845789 2.85 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr17_+_37784749 2.82 ENST00000394265.1
ENST00000394267.2
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr14_-_106963409 2.82 ENST00000390621.2
IGHV1-45
immunoglobulin heavy variable 1-45
chr14_+_22356029 2.70 ENST00000390437.2
TRAV12-2
T cell receptor alpha variable 12-2
chr14_+_22362613 2.52 ENST00000390438.2
TRAV8-4
T cell receptor alpha variable 8-4
chr16_-_33647696 2.42 ENST00000558425.1
ENST00000569103.2
RP11-812E19.9
Uncharacterized protein
chr15_-_20170354 2.41 ENST00000338912.5
IGHV1OR15-9
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr3_+_111717511 2.20 ENST00000478951.1
ENST00000393917.2
TAGLN3
transgelin 3
chr16_+_89696692 2.20 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chr5_+_156607829 2.17 ENST00000422843.3
ITK
IL2-inducible T-cell kinase
chr16_+_33020496 2.16 ENST00000565407.2
IGHV3OR16-8
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr22_-_30925150 2.06 ENST00000437871.1
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr6_-_32731243 2.05 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr3_+_111717600 2.05 ENST00000273368.4
TAGLN3
transgelin 3
chr16_+_33006369 2.03 ENST00000425181.3
IGHV3OR16-10
immunoglobulin heavy variable 3/OR16-10 (non-functional)
chr2_-_36779411 1.98 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr5_-_176056974 1.97 ENST00000510387.1
ENST00000506696.1
SNCB
synuclein, beta
chr19_-_17622269 1.96 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr6_-_32731299 1.96 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr3_+_137728842 1.91 ENST00000183605.5
CLDN18
claudin 18
chr16_+_32077386 1.88 ENST00000354689.6
IGHV3OR16-9
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr22_+_29834572 1.83 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr3_-_116163830 1.82 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr16_+_33629600 1.78 ENST00000562905.2
IGHV3OR16-13
immunoglobulin heavy variable 3/OR16-13 (non-functional)
chr2_+_204801471 1.76 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr5_+_92919043 1.72 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr5_+_35852797 1.69 ENST00000508941.1
IL7R
interleukin 7 receptor
chr5_+_3596168 1.68 ENST00000302006.3
IRX1
iroquois homeobox 1
chr14_-_24732403 1.68 ENST00000206765.6
TGM1
transglutaminase 1
chr13_-_46964177 1.64 ENST00000389908.3
KIAA0226L
KIAA0226-like
chr20_+_58296265 1.61 ENST00000395636.2
ENST00000361300.4
PHACTR3
phosphatase and actin regulator 3
chr4_-_176708533 1.60 ENST00000507520.1
GPM6A
glycoprotein M6A
chr12_-_12837423 1.57 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr15_-_56757329 1.56 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr12_+_25205568 1.54 ENST00000548766.1
ENST00000556887.1
LRMP
lymphoid-restricted membrane protein
chr10_-_15762124 1.53 ENST00000378076.3
ITGA8
integrin, alpha 8
chr3_-_58613323 1.51 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chrX_-_110039286 1.49 ENST00000434224.1
CHRDL1
chordin-like 1
chr14_+_22309368 1.48 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr15_+_51973680 1.47 ENST00000542355.2
SCG3
secretogranin III
chr8_+_24241789 1.45 ENST00000256412.4
ENST00000538205.1
ADAMDEC1
ADAM-like, decysin 1
chr3_+_172361483 1.43 ENST00000598405.1
AC007919.2
HCG1787166; PRO1163; Uncharacterized protein
chr2_-_133429091 1.43 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr16_+_226658 1.40 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr11_-_114466477 1.33 ENST00000375478.3
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr15_+_40453204 1.33 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chrX_-_72095622 1.31 ENST00000290273.5
DMRTC1
DMRT-like family C1
chr3_-_139195350 1.30 ENST00000232217.2
RBP2
retinol binding protein 2, cellular
chr1_+_55464600 1.28 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr8_+_27182862 1.28 ENST00000521164.1
ENST00000346049.5
PTK2B
protein tyrosine kinase 2 beta
chr3_-_180397256 1.25 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr12_-_10320256 1.25 ENST00000538745.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr12_+_13349650 1.25 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1
epithelial membrane protein 1
chr2_+_207024306 1.19 ENST00000236957.5
ENST00000392221.1
ENST00000392222.2
ENST00000445505.1
EEF1B2
eukaryotic translation elongation factor 1 beta 2
chr20_+_42143136 1.17 ENST00000373134.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chrX_+_144908928 1.17 ENST00000408967.2
TMEM257
transmembrane protein 257
chr14_-_24732368 1.16 ENST00000544573.1
TGM1
transglutaminase 1
chr7_-_92855762 1.15 ENST00000453812.2
ENST00000394468.2
HEPACAM2
HEPACAM family member 2
chr16_+_88872176 1.14 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr6_-_160679905 1.13 ENST00000366953.3
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr4_-_46126093 1.09 ENST00000295452.4
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chrX_-_70326455 1.07 ENST00000374251.5
CXorf65
chromosome X open reading frame 65
chr12_-_11548496 1.06 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr6_+_149539053 1.04 ENST00000451095.1
RP1-111D6.3
RP1-111D6.3
chr12_+_25205666 1.04 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr7_-_92848878 1.01 ENST00000341723.4
HEPACAM2
HEPACAM family member 2
chr4_-_123377880 1.01 ENST00000226730.4
IL2
interleukin 2
chr7_-_92848858 1.01 ENST00000440868.1
HEPACAM2
HEPACAM family member 2
chr7_-_766879 1.00 ENST00000537384.1
ENST00000417852.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr17_+_76210267 0.98 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr12_+_13349711 0.97 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr17_-_46703826 0.97 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr6_+_34433844 0.96 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr3_+_239652 0.96 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chrX_-_72095808 0.96 ENST00000373529.5
DMRTC1
DMRT-like family C1
chr1_+_16083098 0.95 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr4_+_37245799 0.93 ENST00000309447.5
KIAA1239
KIAA1239
chr6_-_132272504 0.93 ENST00000367976.3
CTGF
connective tissue growth factor
chr17_+_76210367 0.92 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr6_+_84222220 0.92 ENST00000369700.3
PRSS35
protease, serine, 35
chr11_-_114466471 0.89 ENST00000424261.2
NXPE4
neurexophilin and PC-esterase domain family, member 4
chr3_-_87039662 0.86 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr3_-_121740969 0.86 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr22_-_50523807 0.85 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr6_-_131299929 0.83 ENST00000531356.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr16_+_23194033 0.81 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr7_+_30185496 0.80 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr14_-_24042184 0.79 ENST00000544177.1
JPH4
junctophilin 4
chr14_+_22670455 0.78 ENST00000390460.1
TRAV26-2
T cell receptor alpha variable 26-2
chr7_-_99716914 0.78 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_-_95007193 0.77 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr22_-_50523760 0.76 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr4_-_119274121 0.75 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr17_+_61086917 0.75 ENST00000424789.2
ENST00000389520.4
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr17_+_42015654 0.70 ENST00000565120.1
RP11-527L4.2
Uncharacterized protein
chr12_-_21810726 0.70 ENST00000396076.1
LDHB
lactate dehydrogenase B
chr14_+_24540154 0.70 ENST00000559778.1
ENST00000560761.1
ENST00000557889.1
CPNE6
copine VI (neuronal)
chr3_+_47021168 0.70 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2
neurobeachin-like 2
chr15_+_51973708 0.69 ENST00000558709.1
SCG3
secretogranin III
chr6_+_52051171 0.69 ENST00000340057.1
IL17A
interleukin 17A
chr6_+_116782527 0.68 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr19_-_44259053 0.68 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr11_-_10715117 0.68 ENST00000527509.2
MRVI1
murine retrovirus integration site 1 homolog
chr20_-_17539456 0.67 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr1_+_16083123 0.67 ENST00000510393.1
ENST00000430076.1
FBLIM1
filamin binding LIM protein 1
chrX_-_48776292 0.66 ENST00000376509.4
PIM2
pim-2 oncogene
chr17_+_73642486 0.66 ENST00000579469.1
SMIM6
small integral membrane protein 6
chrX_+_115567767 0.65 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr14_+_24540046 0.64 ENST00000397016.2
ENST00000537691.1
ENST00000560356.1
ENST00000558450.1
CPNE6
copine VI (neuronal)
chr12_-_10320190 0.64 ENST00000543993.1
ENST00000339968.6
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr20_-_44485835 0.64 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
ACOT8
acyl-CoA thioesterase 8
chr19_-_44259136 0.64 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr17_+_76227391 0.64 ENST00000586400.1
ENST00000421688.1
ENST00000374946.3
TMEM235
transmembrane protein 235
chr12_+_25205155 0.63 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr19_-_51893827 0.63 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr12_-_21810765 0.63 ENST00000450584.1
ENST00000350669.1
LDHB
lactate dehydrogenase B
chr3_-_8811288 0.63 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr3_+_126423045 0.63 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr3_+_4535025 0.61 ENST00000302640.8
ENST00000354582.6
ENST00000423119.2
ENST00000357086.4
ENST00000456211.2
ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
chr1_+_228337553 0.61 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr17_+_73642315 0.61 ENST00000556126.2
SMIM6
small integral membrane protein 6
chr15_+_51973550 0.60 ENST00000220478.3
SCG3
secretogranin III
chr4_-_819901 0.60 ENST00000304062.6
CPLX1
complexin 1
chr8_+_67405794 0.59 ENST00000522977.1
ENST00000480005.1
C8orf46
chromosome 8 open reading frame 46
chr8_+_67405755 0.59 ENST00000521495.1
C8orf46
chromosome 8 open reading frame 46
chr12_-_75603482 0.58 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr16_-_66952742 0.58 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr10_-_14596140 0.58 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr12_+_25205446 0.57 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr2_+_79252822 0.57 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chr2_+_79252834 0.57 ENST00000409471.1
REG3G
regenerating islet-derived 3 gamma
chr19_-_38720354 0.57 ENST00000416611.1
DPF1
D4, zinc and double PHD fingers family 1
chr6_+_84222194 0.57 ENST00000536636.1
PRSS35
protease, serine, 35
chr2_+_79252804 0.56 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr22_-_50523843 0.56 ENST00000535444.1
ENST00000431262.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_+_140474181 0.55 ENST00000194155.4
PCDHB2
protocadherin beta 2
chr13_+_108921977 0.54 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr11_-_67141640 0.54 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr1_-_67266939 0.54 ENST00000304526.2
INSL5
insulin-like 5
chr6_+_69942298 0.53 ENST00000238918.8
BAI3
brain-specific angiogenesis inhibitor 3
chr12_-_75603202 0.52 ENST00000393288.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr15_+_45422178 0.51 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr7_+_99816859 0.51 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr12_-_102591604 0.51 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr16_+_22501658 0.50 ENST00000415833.2
NPIPB5
nuclear pore complex interacting protein family, member B5
chr1_-_160924589 0.50 ENST00000368029.3
ITLN2
intelectin 2
chr11_-_132812987 0.49 ENST00000541867.1
OPCML
opioid binding protein/cell adhesion molecule-like
chr1_+_16348525 0.48 ENST00000331433.4
CLCNKA
chloride channel, voltage-sensitive Ka
chrX_-_110655306 0.48 ENST00000371993.2
DCX
doublecortin
chr11_+_35211429 0.48 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr12_-_75603643 0.47 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_-_9003586 0.47 ENST00000380951.5
MUC16
mucin 16, cell surface associated
chr17_-_8198636 0.46 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr14_-_106068065 0.46 ENST00000390541.2
IGHE
immunoglobulin heavy constant epsilon
chr8_-_86162077 0.46 ENST00000551479.1
RP11-219B4.6
Uncharacterized protein
chr1_+_120839412 0.46 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr3_+_67048721 0.45 ENST00000295568.4
ENST00000484414.1
ENST00000460576.1
ENST00000417314.2
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr8_+_104310661 0.45 ENST00000522566.1
FZD6
frizzled family receptor 6
chr2_-_159313214 0.45 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
CCDC148
coiled-coil domain containing 148
chr3_-_150966902 0.45 ENST00000424796.2
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr15_-_70387120 0.45 ENST00000539550.1
TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr5_+_149737202 0.44 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr11_+_12108410 0.44 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr2_-_68547019 0.42 ENST00000409862.1
CNRIP1
cannabinoid receptor interacting protein 1
chr1_+_158223923 0.41 ENST00000289429.5
CD1A
CD1a molecule
chr2_-_68547061 0.41 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr11_-_133826852 0.41 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr4_+_15341442 0.40 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr3_+_10183447 0.40 ENST00000345392.2
VHL
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
chr14_+_63671577 0.40 ENST00000555125.1
RHOJ
ras homolog family member J
chr15_-_35047166 0.40 ENST00000290374.4
GJD2
gap junction protein, delta 2, 36kDa
chr7_-_38295997 0.40 ENST00000390334.1
TRGJP2
T cell receptor gamma joining P2
chr6_+_149539106 0.40 ENST00000443992.1
RP1-111D6.3
RP1-111D6.3
chr6_+_43968306 0.40 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr3_-_53290016 0.39 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr4_-_164253738 0.38 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr8_+_128426535 0.38 ENST00000465342.2
POU5F1B
POU class 5 homeobox 1B
chrX_+_591524 0.38 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr16_-_55478666 0.37 ENST00000565307.1
RP11-212I21.2
RP11-212I21.2
chr12_+_25205628 0.37 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr15_-_77363441 0.36 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr17_-_62502399 0.35 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr12_-_49504449 0.34 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr17_-_28661065 0.34 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr13_-_46756351 0.33 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_36764142 0.33 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr18_+_44497455 0.33 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0016999 antibiotic metabolic process(GO:0016999)
0.6 1.7 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.5 1.6 GO:0034059 response to anoxia(GO:0034059)
0.4 35.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.4 1.7 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.4 2.8 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.4 1.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.3 1.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 1.5 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.3 1.5 GO:0048749 compound eye development(GO:0048749)
0.3 2.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 1.0 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 29.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 1.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.2 1.3 GO:2000537 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.7 GO:0002636 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.1 1.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 2.2 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.5 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 1.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.8 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 0.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:0005997 xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.5 GO:0042335 cuticle development(GO:0042335)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 2.2 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 1.1 GO:1901374 acetate ester transport(GO:1901374)
0.1 0.4 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 1.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.1 1.9 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 2.2 GO:0032060 bleb assembly(GO:0032060)
0.1 1.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.1 1.6 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.2 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.2 GO:0048789 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 1.4 GO:0015671 oxygen transport(GO:0015671)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.9 GO:0014029 neural crest formation(GO:0014029)
0.1 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.3 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 1.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.7 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.3 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.3 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.0 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.8 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.6 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.4 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 1.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 1.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.3 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 4.0 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 1.1 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.4 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 3.2 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.7 GO:0030220 platelet formation(GO:0030220)
0.0 2.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.2 GO:0010663 positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 3.2 GO:0007098 centrosome cycle(GO:0007098)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 1.0 GO:0031103 axon regeneration(GO:0031103)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0007625 grooming behavior(GO:0007625)
0.0 0.6 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.8 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0030578 PML body organization(GO:0030578)
0.0 0.0 GO:1905244 regulation of modification of synaptic structure(GO:1905244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 35.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.4 1.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.3 1.5 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 1.9 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 4.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.1 1.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 1.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0030891 VCB complex(GO:0030891)
0.0 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.8 GO:0008091 spectrin(GO:0008091)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 1.7 GO:0032809 axolemma(GO:0030673) neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 3.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.8 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.8 GO:0034706 sodium channel complex(GO:0034706)
0.0 1.7 GO:0001533 cornified envelope(GO:0001533)
0.0 2.6 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.6 GO:0071565 nBAF complex(GO:0071565)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 2.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 3.6 GO:0043209 myelin sheath(GO:0043209)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 3.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.2 GO:0030496 midbody(GO:0030496)
0.0 1.6 GO:0016234 inclusion body(GO:0016234)
0.0 1.9 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 2.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.5 35.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.4 1.7 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 1.2 GO:0032093 SAM domain binding(GO:0032093)
0.4 1.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 0.9 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.3 1.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 4.0 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.2 2.2 GO:0034235 GPI anchor binding(GO:0034235) metallodipeptidase activity(GO:0070573)
0.2 2.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 29.8 GO:0003823 antigen binding(GO:0003823)
0.1 2.0 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.0 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.1 0.4 GO:0004802 transketolase activity(GO:0004802)
0.1 1.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 1.7 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.3 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 1.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 1.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.7 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 0.1 GO:0046978 peptide antigen-transporting ATPase activity(GO:0015433) TAP binding(GO:0046977) TAP1 binding(GO:0046978)
0.1 1.6 GO:0031005 filamin binding(GO:0031005)
0.1 1.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 1.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.6 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.8 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.8 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 1.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.5 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.3 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.9 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 1.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.3 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 2.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 2.3 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 1.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.7 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.9 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.3 REACTOME TRANSLATION Genes involved in Translation
0.0 0.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis