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Results for NR1H2

Z-value: 1.15

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Transcription factors associated with NR1H2

Gene Symbol Gene ID Gene Info
ENSG00000131408.9 nuclear receptor subfamily 1 group H member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1H2hg19_v2_chr19_+_50832895_50832928-0.364.2e-02Click!

Activity profile of NR1H2 motif

Sorted Z-values of NR1H2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_77774897 6.40 ENST00000281030.2
thyroid hormone responsive
chr7_+_80253387 2.74 ENST00000438020.1
CD36 molecule (thrombospondin receptor)
chr9_-_107690420 2.57 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr12_-_47226152 2.30 ENST00000546940.1
solute carrier family 38, member 4
chr16_+_56995762 2.28 ENST00000200676.3
ENST00000379780.2
cholesteryl ester transfer protein, plasma
chr11_-_118083600 2.27 ENST00000524477.1
adhesion molecule, interacts with CXADR antigen 1
chr2_-_216946500 2.25 ENST00000265322.7
peroxisomal trans-2-enoyl-CoA reductase
chr20_+_5987890 2.22 ENST00000378868.4
cardiolipin synthase 1
chr1_-_237167718 2.20 ENST00000464121.2
metallothionein 1H-like 1
chr12_+_32115400 2.18 ENST00000381054.3
KIAA1551
chr2_+_234104079 2.15 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_2042065 2.07 ENST00000591588.1
ENST00000591142.1
MAP kinase interacting serine/threonine kinase 2
chr11_+_10326612 2.03 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
adrenomedullin
chr4_-_71532601 2.01 ENST00000510614.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532668 1.97 ENST00000510437.1
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr16_-_68034452 1.91 ENST00000575510.1
dipeptidase 2
chr15_-_90358564 1.88 ENST00000559874.1
alanyl (membrane) aminopeptidase
chr22_-_24096562 1.88 ENST00000398465.3
pre-B lymphocyte 3
chr10_-_70287172 1.81 ENST00000539557.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr12_+_56511943 1.79 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr16_+_72042487 1.74 ENST00000572887.1
ENST00000219240.4
ENST00000574309.1
ENST00000576145.1
dihydroorotate dehydrogenase (quinone)
chr10_-_72648541 1.73 ENST00000299299.3
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
chr14_+_105046094 1.70 ENST00000331952.2
chromosome 14 open reading frame 180
chr10_-_70287231 1.70 ENST00000609923.1
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr16_+_56995854 1.64 ENST00000566128.1
cholesteryl ester transfer protein, plasma
chr17_+_7184986 1.62 ENST00000317370.8
ENST00000571308.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr8_-_48651648 1.59 ENST00000408965.3
CCAAT/enhancer binding protein (C/EBP), delta
chr5_+_35856951 1.55 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr7_+_16700806 1.55 ENST00000446596.1
ENST00000438834.1
basic leucine zipper and W2 domains 2
chr17_+_32683456 1.52 ENST00000225844.2
chemokine (C-C motif) ligand 13
chr17_-_26694979 1.52 ENST00000438614.1
vitronectin
chr17_+_77018896 1.52 ENST00000578229.1
C1q and tumor necrosis factor related protein 1
chr21_+_43619796 1.51 ENST00000398457.2
ATP-binding cassette, sub-family G (WHITE), member 1
chr17_-_26695013 1.50 ENST00000555059.2
Homeobox protein SEBOX
chr11_+_32851487 1.48 ENST00000257836.3
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr19_+_41092680 1.48 ENST00000594298.1
ENST00000597396.1
SH3KBP1 binding protein 1
chr16_-_68034470 1.47 ENST00000412757.2
dipeptidase 2
chr12_-_7125770 1.45 ENST00000261407.4
lysophosphatidylcholine acyltransferase 3
chr22_-_24096630 1.39 ENST00000248948.3
pre-B lymphocyte 3
chr20_+_43343886 1.37 ENST00000190983.4
WNT1 inducible signaling pathway protein 2
chr5_+_96424779 1.36 ENST00000509481.1
Uncharacterized protein
chr17_+_8213539 1.35 ENST00000583529.1
Rho guanine nucleotide exchange factor (GEF) 15
chr6_+_30687978 1.34 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr16_+_21623392 1.32 ENST00000562961.1
methyltransferase like 9
chr4_+_108910870 1.31 ENST00000403312.1
ENST00000603302.1
ENST00000309522.3
hydroxyacyl-CoA dehydrogenase
chr16_-_11723066 1.31 ENST00000576036.1
lipopolysaccharide-induced TNF factor
chr14_-_102976135 1.28 ENST00000560748.1
ankyrin repeat domain 9
chr4_-_84205905 1.28 ENST00000311461.7
ENST00000311469.4
ENST00000439031.2
coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
chr20_+_43343517 1.28 ENST00000372865.4
WNT1 inducible signaling pathway protein 2
chr2_+_238877424 1.27 ENST00000434655.1
ubiquitin-conjugating enzyme E2F (putative)
chr19_-_49658387 1.26 ENST00000595625.1
histidine rich calcium binding protein
chr5_-_133968529 1.26 ENST00000402673.2
SAR1 homolog B (S. cerevisiae)
chr19_-_38806540 1.26 ENST00000592694.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr17_-_3595042 1.21 ENST00000552723.1
purinergic receptor P2X, ligand-gated ion channel, 5
chr1_+_87595433 1.20 ENST00000469312.2
ENST00000490006.2
long intergenic non-protein coding RNA 1140
chr1_-_153950098 1.20 ENST00000356648.1
jumping translocation breakpoint
chr2_+_27255806 1.19 ENST00000238788.9
ENST00000404032.3
transmembrane protein 214
chr3_+_39371255 1.19 ENST00000414803.1
ENST00000545843.1
chemokine (C-C motif) receptor 8
chr18_+_21693306 1.18 ENST00000540918.2
tetratricopeptide repeat domain 39C
chr11_+_86748957 1.18 ENST00000526733.1
ENST00000532959.1
transmembrane protein 135
chr10_-_76818272 1.17 ENST00000338487.5
dual specificity phosphatase and pro isomerase domain containing 1
chr4_-_71705027 1.17 ENST00000545193.1
G-rich RNA sequence binding factor 1
chr4_-_71705060 1.16 ENST00000514161.1
G-rich RNA sequence binding factor 1
chr7_+_45067265 1.15 ENST00000474617.1
cerebral cavernous malformation 2
chr20_-_46041046 1.14 ENST00000437920.1
RP1-148H17.1
chr22_-_33968239 1.14 ENST00000452586.2
ENST00000421768.1
like-glycosyltransferase
chr22_+_23247030 1.14 ENST00000390324.2
immunoglobulin lambda joining 3
chr11_+_844406 1.13 ENST00000397404.1
tetraspanin 4
chr3_-_127309550 1.13 ENST00000296210.7
ENST00000355552.3
transmembrane protein, adipocyte asscociated 1
chr12_-_113841678 1.12 ENST00000552280.1
ENST00000257549.4
serine dehydratase
chr15_-_89010607 1.11 ENST00000312475.4
mitochondrial ribosomal protein L46
chr2_+_168043793 1.11 ENST00000409273.1
ENST00000409605.1
xin actin-binding repeat containing 2
chr17_+_27047570 1.10 ENST00000472628.1
ENST00000578181.1
ribosomal protein L23a
chr19_+_52264104 1.09 ENST00000340023.6
formyl peptide receptor 2
chr15_+_81589254 1.09 ENST00000394652.2
interleukin 16
chr11_+_827248 1.09 ENST00000527089.1
ENST00000530183.1
EF-hand calcium binding domain 4A
chr19_-_38806390 1.07 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr19_+_15752088 1.07 ENST00000585846.1
cytochrome P450, family 4, subfamily F, polypeptide 3
chr17_-_17480779 1.07 ENST00000395782.1
phosphatidylethanolamine N-methyltransferase
chr11_-_82611448 1.06 ENST00000393399.2
ENST00000313010.3
prolylcarboxypeptidase (angiotensinase C)
chr5_+_76145826 1.06 ENST00000513010.1
S100 calcium binding protein Z
chr17_+_77019030 1.05 ENST00000580454.1
C1q and tumor necrosis factor related protein 1
chr16_+_30484021 1.03 ENST00000358164.5
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr2_-_74699770 1.03 ENST00000409710.1
mitochondrial ribosomal protein L53
chr1_-_153949751 1.02 ENST00000428469.1
jumping translocation breakpoint
chr19_-_38806560 1.01 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chr1_-_161207986 1.00 ENST00000506209.1
ENST00000367980.2
nuclear receptor subfamily 1, group I, member 3
chr14_-_73925225 0.99 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
numb homolog (Drosophila)
chr11_+_86749035 0.99 ENST00000305494.5
ENST00000535167.1
transmembrane protein 135
chr11_-_118789613 0.99 ENST00000532899.1
B-cell CLL/lymphoma 9-like
chr12_-_6677422 0.98 ENST00000382421.3
ENST00000545200.1
ENST00000399466.2
ENST00000536124.1
ENST00000540228.1
ENST00000542867.1
ENST00000545492.1
ENST00000322166.5
ENST00000545915.1
NOP2 nucleolar protein
chr1_-_161207953 0.96 ENST00000367982.4
nuclear receptor subfamily 1, group I, member 3
chr12_-_56694142 0.96 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chr1_-_9714644 0.95 ENST00000377320.3
chromosome 1 open reading frame 200
chr5_-_180671172 0.95 ENST00000512805.1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr2_-_219146839 0.94 ENST00000425694.1
transmembrane BAX inhibitor motif containing 1
chr16_+_53133070 0.92 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chrX_-_2847366 0.92 ENST00000381154.1
arylsulfatase D
chr14_-_74462922 0.92 ENST00000553284.1
ectonucleoside triphosphate diphosphohydrolase 5
chr15_+_89010923 0.90 ENST00000353598.6
mitochondrial ribosomal protein S11
chr13_+_49684445 0.89 ENST00000398316.3
fibronectin type III domain containing 3A
chr5_+_179135246 0.89 ENST00000508787.1
calnexin
chr17_+_4675175 0.88 ENST00000270560.3
transmembrane 4 L six family member 5
chr14_-_94970559 0.87 ENST00000556881.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr12_-_9913489 0.86 ENST00000228434.3
ENST00000536709.1
CD69 molecule
chr4_-_140216948 0.85 ENST00000265500.4
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr20_+_3052264 0.85 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr11_+_119039414 0.84 ENST00000409991.1
ENST00000292199.2
ENST00000409265.4
ENST00000409109.1
NLR family member X1
chr10_+_101491968 0.84 ENST00000370476.5
ENST00000370472.4
cutC copper transporter
chr9_-_130829588 0.83 ENST00000373078.4
nuclear apoptosis inducing factor 1
chr3_-_127309879 0.83 ENST00000489960.1
ENST00000490290.1
transmembrane protein, adipocyte asscociated 1
chr2_-_165697920 0.82 ENST00000342193.4
ENST00000375458.2
cordon-bleu WH2 repeat protein-like 1
chr22_+_36113919 0.81 ENST00000249044.2
apolipoprotein L, 5
chr17_-_56350797 0.81 ENST00000577220.1
myeloperoxidase
chr19_+_35899569 0.80 ENST00000600405.1
AC002511.1
chr19_+_15751689 0.80 ENST00000586182.2
ENST00000591058.1
ENST00000221307.8
cytochrome P450, family 4, subfamily F, polypeptide 3
chr17_-_8151353 0.80 ENST00000315684.8
CTS telomere maintenance complex component 1
chr6_+_37475109 0.80 ENST00000570443.2
RP1-153P14.8
chr12_+_120972606 0.79 ENST00000413266.2
ring finger protein 10
chr8_-_144700212 0.79 ENST00000526290.1
tissue specific transplantation antigen P35B
chr4_-_2965052 0.78 ENST00000398071.4
ENST00000502735.1
ENST00000314262.6
ENST00000416614.2
NOP14 nucleolar protein
chr11_+_86748998 0.77 ENST00000525018.1
ENST00000355734.4
transmembrane protein 135
chr9_+_95736758 0.75 ENST00000337352.6
FYVE, RhoGEF and PH domain containing 3
chr21_-_35281399 0.74 ENST00000418933.1
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr16_+_577697 0.74 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
calpain 15
chrX_+_48542168 0.73 ENST00000376701.4
Wiskott-Aldrich syndrome
chr21_-_46340807 0.73 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_34639733 0.72 ENST00000374021.1
chromosome 6 open reading frame 106
chr20_+_19738792 0.72 ENST00000412571.1
RP1-122P22.2
chr19_-_49121054 0.71 ENST00000546623.1
ENST00000084795.5
ribosomal protein L18
chr8_+_38065104 0.70 ENST00000521311.1
BCL2-associated athanogene 4
chr19_+_1026298 0.70 ENST00000263097.4
calponin 2
chr1_+_22962948 0.70 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr16_-_19533404 0.69 ENST00000353258.3
glycerophosphodiester phosphodiesterase 1
chr5_+_76145920 0.69 ENST00000317593.4
S100 calcium binding protein Z
chr16_+_4674814 0.69 ENST00000415496.1
ENST00000587747.1
ENST00000399577.5
ENST00000588994.1
ENST00000586183.1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr3_+_39371191 0.69 ENST00000326306.4
chemokine (C-C motif) receptor 8
chr14_-_73924954 0.68 ENST00000555307.1
ENST00000554818.1
numb homolog (Drosophila)
chr2_-_3521518 0.67 ENST00000382093.5
acireductone dioxygenase 1
chr11_-_62420757 0.67 ENST00000330574.2
integrator complex subunit 5
chr20_-_48747662 0.67 ENST00000371656.2
transmembrane protein 189
chr17_-_5026397 0.67 ENST00000250076.3
zinc finger protein 232
chr12_+_52281744 0.66 ENST00000301190.6
ENST00000538991.1
ankyrin repeat domain 33
chr16_+_29467780 0.66 ENST00000395400.3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr17_+_76183398 0.65 ENST00000409257.5
arylformamidase
chr19_-_6670128 0.65 ENST00000245912.3
tumor necrosis factor (ligand) superfamily, member 14
chr14_-_106114739 0.65 ENST00000460164.1
RP11-731F5.2
chr8_+_132916318 0.65 ENST00000254624.5
ENST00000522709.1
EFR3 homolog A (S. cerevisiae)
chr8_-_13134246 0.64 ENST00000503161.2
deleted in liver cancer 1
chr17_-_79604075 0.64 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
nuclear protein localization 4 homolog (S. cerevisiae)
chr2_+_207630081 0.63 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr19_+_16254488 0.63 ENST00000588246.1
ENST00000593031.1
hematopoietic SH2 domain containing
chr11_+_119039069 0.63 ENST00000422249.1
NLR family member X1
chr11_+_119038897 0.63 ENST00000454811.1
ENST00000449394.1
NLR family member X1
chr15_+_96876340 0.62 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr12_-_56123444 0.62 ENST00000546457.1
ENST00000549117.1
CD63 molecule
chr11_+_65190245 0.61 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_+_10290822 0.61 ENST00000377083.1
kinesin family member 1B
chr16_+_56969284 0.61 ENST00000568358.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_+_36335351 0.61 ENST00000373206.1
argonaute RISC catalytic component 1
chr5_-_138862326 0.60 ENST00000330794.4
transmembrane protein 173
chr19_+_50094866 0.60 ENST00000418929.2
proline rich 12
chr19_-_50420918 0.59 ENST00000595761.1
nucleoporin 62kDa
chr11_+_86748863 0.58 ENST00000340353.7
transmembrane protein 135
chr19_+_17622415 0.58 ENST00000252603.2
ENST00000600923.1
6-phosphogluconolactonase
chr2_+_223725723 0.57 ENST00000535678.1
acyl-CoA synthetase long-chain family member 3
chr1_+_161035655 0.56 ENST00000600454.1
Uncharacterized protein
chr1_-_161208013 0.56 ENST00000515452.1
ENST00000367983.4
nuclear receptor subfamily 1, group I, member 3
chr21_-_46340770 0.56 ENST00000397854.3
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr14_-_102976091 0.56 ENST00000286918.4
ankyrin repeat domain 9
chr11_+_62652649 0.55 ENST00000539507.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chrX_+_1455478 0.55 ENST00000331035.4
interleukin 3 receptor, alpha (low affinity)
chr17_-_76183111 0.54 ENST00000405273.1
ENST00000590862.1
ENST00000590430.1
ENST00000586613.1
thymidine kinase 1, soluble
chr4_-_39640700 0.53 ENST00000295958.5
small integral membrane protein 14
chr8_-_27941359 0.53 ENST00000418860.1
nuclear GTPase, germinal center associated
chr17_-_17726907 0.53 ENST00000423161.3
sterol regulatory element binding transcription factor 1
chr8_+_142402089 0.53 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
protein tyrosine phosphatase type IVA, member 3
chr14_-_57197224 0.52 ENST00000554597.1
ENST00000556696.1
Uncharacterized protein
chr12_-_125399573 0.52 ENST00000339647.5
ubiquitin C
chr8_-_121457332 0.52 ENST00000518918.1
mitochondrial ribosomal protein L13
chr19_-_36391434 0.52 ENST00000396901.1
ENST00000585925.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr19_-_45873642 0.51 ENST00000485403.2
ENST00000586856.1
ENST00000586131.1
ENST00000391940.4
ENST00000221481.6
ENST00000391944.3
ENST00000391945.4
excision repair cross-complementing rodent repair deficiency, complementation group 2
chr12_+_52282001 0.51 ENST00000340970.4
ankyrin repeat domain 33
chr8_+_74903580 0.50 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr11_+_67171391 0.49 ENST00000312390.5
TBC1 domain family, member 10C
chr12_+_123942188 0.49 ENST00000526639.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr14_-_70826438 0.49 ENST00000389912.6
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr11_-_62521614 0.49 ENST00000527994.1
ENST00000394807.3
zinc finger and BTB domain containing 3
chr1_+_10459111 0.47 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
phosphogluconate dehydrogenase
chr1_+_210001309 0.47 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chr17_-_62097904 0.46 ENST00000583366.1
intercellular adhesion molecule 2
chr9_-_36400213 0.46 ENST00000259605.6
ENST00000353739.4
ring finger protein 38
chr12_-_56122761 0.46 ENST00000552164.1
ENST00000420846.3
ENST00000257857.4
CD63 molecule
chr16_+_21312170 0.46 ENST00000338573.5
ENST00000561968.1
CRYM antisense RNA 1
chr7_+_2687173 0.46 ENST00000403167.1
tweety family member 3
chr1_+_24117627 0.46 ENST00000400061.1
lysophospholipase II
chr16_+_30194118 0.45 ENST00000563778.1
coronin, actin binding protein, 1A
chr7_+_56131917 0.45 ENST00000434526.2
ENST00000275607.9
ENST00000395435.2
ENST00000413952.2
ENST00000342190.6
ENST00000437307.2
ENST00000413756.1
ENST00000451338.1
sulfatase modifying factor 2
chrX_+_107334983 0.45 ENST00000457035.1
ENST00000545696.1
autophagy related 4A, cysteine peptidase
chr6_-_31763408 0.45 ENST00000444930.2
valyl-tRNA synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1H2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.6 1.7 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.5 6.5 GO:0055091 phospholipid homeostasis(GO:0055091)
0.4 2.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.4 1.3 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.4 1.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.3 2.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 2.0 GO:0036100 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.3 0.8 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.3 1.3 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.3 0.8 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.3 6.4 GO:0006853 carnitine shuttle(GO:0006853)
0.2 2.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.2 2.7 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 0.7 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.2 1.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.2 2.0 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.2 0.8 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.2 0.7 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.2 2.7 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 1.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.2 2.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 1.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.9 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.2 0.6 GO:1904647 response to rotenone(GO:1904647)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.7 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.8 GO:0048539 bone marrow development(GO:0048539)
0.1 2.0 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.6 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.9 GO:0051697 protein delipidation(GO:0051697)
0.1 1.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 1.0 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.7 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.4 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.1 0.6 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.1 0.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.6 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.5 GO:0032796 uropod organization(GO:0032796)
0.1 0.8 GO:0001878 response to yeast(GO:0001878)
0.1 0.4 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.6 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.9 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 1.1 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 1.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.2 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.6 GO:0060356 leucine import(GO:0060356)
0.1 0.5 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.2 GO:0042245 RNA repair(GO:0042245)
0.1 4.2 GO:0032094 response to food(GO:0032094)
0.1 0.8 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.7 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.5 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 1.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 1.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.1 1.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 1.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 1.3 GO:0045116 protein neddylation(GO:0045116)
0.1 1.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.7 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.4 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.5 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 1.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.9 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.2 GO:2000678 negative regulation of transcription regulatory region DNA binding(GO:2000678)
0.0 1.6 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 2.3 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.3 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.8 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 2.6 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 1.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.6 GO:0035458 positive regulation of protein import into nucleus, translocation(GO:0033160) cellular response to interferon-beta(GO:0035458)
0.0 1.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.6 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.2 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 1.3 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 2.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.7 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 2.7 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 2.0 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 3.3 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 0.8 GO:0010039 response to iron ion(GO:0010039)
0.0 3.5 GO:0009108 coenzyme biosynthetic process(GO:0009108)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 1.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 4.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.7 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 1.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.1 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.4 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0044299 C-fiber(GO:0044299)
0.4 1.5 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 0.8 GO:0030689 Noc complex(GO:0030689)
0.2 2.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.2 1.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.7 GO:0005602 complement component C1 complex(GO:0005602)
0.1 6.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.6 GO:1990037 Lewy body core(GO:1990037)
0.1 0.4 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 2.7 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.9 GO:0000243 commitment complex(GO:0000243)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 3.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 6.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 2.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.6 GO:0005642 annulate lamellae(GO:0005642)
0.0 5.1 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.0 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 2.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 3.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.1 GO:0031941 filamentous actin(GO:0031941)
0.0 5.6 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.4 GO:0016605 PML body(GO:0016605)
0.0 1.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 9.1 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0017129 triglyceride binding(GO:0017129)
0.7 2.2 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.7 2.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.6 2.6 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.6 1.9 GO:0097259 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.6 1.7 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.5 1.5 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.4 1.7 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.4 2.5 GO:0004882 androgen receptor activity(GO:0004882)
0.4 1.5 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 1.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.4 1.1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 1.3 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.3 1.0 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.3 1.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 1.5 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 2.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.3 0.8 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.2 2.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.2 1.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.2 0.7 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.2 2.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 0.6 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.2 0.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.4 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 1.1 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 1.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.7 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.6 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.1 0.3 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 1.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.5 GO:0004797 thymidine kinase activity(GO:0004797)
0.1 0.4 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 1.9 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 3.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.2 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 1.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.8 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 1.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.8 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.2 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.9 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 3.5 GO:0015297 antiporter activity(GO:0015297)
0.0 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.0 GO:0005179 hormone activity(GO:0005179)
0.0 1.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 2.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.9 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 3.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 2.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 2.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID IGF1 PATHWAY IGF1 pathway
0.0 1.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 ST ADRENERGIC Adrenergic Pathway
0.0 2.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 1.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 2.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 8.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.2 3.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 6.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 4.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 4.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 2.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 2.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.3 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery