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Illumina Body Map 2

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Results for NR1I2

Z-value: 1.14

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119501557_1195015570.222.2e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_91576429 5.42 ENST00000552145.1
ENST00000546745.1
decorin
chr20_+_43343886 3.70 ENST00000190983.4
WNT1 inducible signaling pathway protein 2
chr15_+_96875657 3.46 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr15_+_96876340 3.19 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr7_-_27169801 3.16 ENST00000511914.1
homeobox A4
chr1_-_173886491 2.82 ENST00000367698.3
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr6_-_75912508 2.79 ENST00000416123.2
collagen, type XII, alpha 1
chr1_-_178840157 2.72 ENST00000367629.1
ENST00000234816.2
angiopoietin-like 1
chr3_-_49722523 2.67 ENST00000448220.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr8_-_82395461 2.67 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr1_+_201979743 2.65 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr1_+_201979645 2.57 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr8_+_99956662 2.49 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
odd-skipped related transciption factor 2
chr7_+_134576151 2.43 ENST00000393118.2
caldesmon 1
chr15_-_65067773 2.39 ENST00000300069.4
RNA binding protein with multiple splicing 2
chr9_-_129885010 2.37 ENST00000373425.3
angiopoietin-like 2
chr1_+_199996733 2.32 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr12_-_91576561 2.28 ENST00000547568.2
ENST00000552962.1
decorin
chr9_-_129884902 2.28 ENST00000373417.1
angiopoietin-like 2
chr11_+_117073850 2.22 ENST00000529622.1
transgelin
chr3_+_112930306 2.22 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr17_-_34345002 2.20 ENST00000293280.2
chemokine (C-C motif) ligand 23
chr17_-_46682321 2.19 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr12_-_91576750 2.17 ENST00000228329.5
ENST00000303320.3
ENST00000052754.5
decorin
chr13_-_110959478 2.15 ENST00000543140.1
ENST00000375820.4
collagen, type IV, alpha 1
chr1_+_199996702 2.15 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr1_+_200011711 2.13 ENST00000544748.1
nuclear receptor subfamily 5, group A, member 2
chr1_+_16083154 2.11 ENST00000375771.1
filamin binding LIM protein 1
chr4_-_110723134 2.10 ENST00000510800.1
ENST00000512148.1
complement factor I
chr9_-_14313893 2.09 ENST00000380921.3
ENST00000380959.3
nuclear factor I/B
chr4_-_110723335 2.05 ENST00000394634.2
complement factor I
chr1_+_16083098 2.03 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr4_-_110723194 2.03 ENST00000394635.3
complement factor I
chr1_+_22970119 2.03 ENST00000374640.4
ENST00000374639.3
ENST00000374637.1
complement component 1, q subcomponent, C chain
chr17_-_34344991 2.02 ENST00000591423.1
chemokine (C-C motif) ligand 23
chr1_+_16083123 2.00 ENST00000510393.1
ENST00000430076.1
filamin binding LIM protein 1
chr8_+_11561660 1.96 ENST00000526716.1
ENST00000335135.4
ENST00000528027.1
GATA binding protein 4
chr11_+_69831982 1.92 ENST00000534086.1
RP11-626H12.1
chr8_+_99956759 1.90 ENST00000522510.1
ENST00000457907.2
odd-skipped related transciption factor 2
chr10_+_24755416 1.88 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
chr12_-_96184533 1.87 ENST00000343702.4
ENST00000344911.4
netrin 4
chr1_+_82165350 1.83 ENST00000359929.3
latrophilin 2
chr7_-_107642348 1.82 ENST00000393561.1
laminin, beta 1
chr22_+_21128167 1.82 ENST00000215727.5
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr3_+_12330560 1.81 ENST00000397026.2
peroxisome proliferator-activated receptor gamma
chr12_+_52626898 1.80 ENST00000331817.5
keratin 7
chr1_+_145413268 1.80 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
hemochromatosis type 2 (juvenile)
chr10_-_33625154 1.79 ENST00000265371.4
neuropilin 1
chr12_-_96184913 1.77 ENST00000538383.1
netrin 4
chr1_-_12679171 1.75 ENST00000606790.1
RP11-474O21.5
chrX_+_99839799 1.75 ENST00000373031.4
tenomodulin
chr2_-_75426183 1.74 ENST00000409848.3
tachykinin receptor 1
chr3_+_112930387 1.73 ENST00000485230.1
BOC cell adhesion associated, oncogene regulated
chr9_-_14313641 1.73 ENST00000380953.1
nuclear factor I/B
chr6_-_154751629 1.70 ENST00000424998.1
CNKSR family member 3
chr2_+_192141611 1.69 ENST00000392316.1
myosin IB
chr5_-_33892204 1.69 ENST00000504830.1
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr1_+_159557607 1.67 ENST00000255040.2
amyloid P component, serum
chr1_+_196788887 1.67 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr6_+_142623063 1.66 ENST00000296932.8
ENST00000367609.3
G protein-coupled receptor 126
chr2_+_234621551 1.65 ENST00000608381.1
ENST00000373414.3
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr3_-_58196688 1.65 ENST00000486455.1
deoxyribonuclease I-like 3
chr9_-_14314066 1.63 ENST00000397575.3
nuclear factor I/B
chr6_+_142622991 1.63 ENST00000230173.6
ENST00000367608.2
G protein-coupled receptor 126
chr1_+_207277632 1.62 ENST00000421786.1
complement component 4 binding protein, alpha
chr4_+_124317940 1.62 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_86230315 1.60 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr9_+_135457530 1.59 ENST00000263610.2
BarH-like homeobox 1
chr2_+_234627424 1.57 ENST00000373409.3
UDP glucuronosyltransferase 1 family, polypeptide A4
chr1_+_22962948 1.57 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr17_-_7167279 1.56 ENST00000571932.2
claudin 7
chr3_+_112929850 1.55 ENST00000464546.1
BOC cell adhesion associated, oncogene regulated
chr5_+_73109339 1.55 ENST00000296799.4
Rho guanine nucleotide exchange factor (GEF) 28
chr16_+_71392616 1.55 ENST00000349553.5
ENST00000302628.4
ENST00000562305.1
calbindin 2
chr2_-_105030466 1.55 ENST00000449772.1
AC068535.3
chr1_-_154458520 1.53 ENST00000486773.1
Src homology 2 domain containing E
chr2_+_223916862 1.53 ENST00000604125.1
potassium voltage-gated channel, Isk-related family, member 4
chr17_-_74528128 1.53 ENST00000590175.1
cytoglobin
chr4_-_70361579 1.52 ENST00000512583.1
UDP glucuronosyltransferase 2 family, polypeptide B4
chr17_-_46035187 1.51 ENST00000300557.2
proline rich 15-like
chr7_-_99381884 1.50 ENST00000336411.2
cytochrome P450, family 3, subfamily A, polypeptide 4
chr10_-_131762105 1.50 ENST00000368648.3
ENST00000355311.5
early B-cell factor 3
chr2_+_69240302 1.50 ENST00000303714.4
anthrax toxin receptor 1
chr5_+_92919043 1.49 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr6_+_12007963 1.49 ENST00000607445.1
RP11-456H18.2
chr3_-_58196939 1.49 ENST00000394549.2
ENST00000461914.3
deoxyribonuclease I-like 3
chr3_+_193853927 1.46 ENST00000232424.3
hes family bHLH transcription factor 1
chr15_-_75017711 1.46 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
cytochrome P450, family 1, subfamily A, polypeptide 1
chr1_+_196912902 1.45 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr10_-_74714533 1.44 ENST00000373032.3
phospholipase A2, group XIIB
chr15_+_65337708 1.43 ENST00000334287.2
solute carrier family 51, beta subunit
chr6_+_152128371 1.42 ENST00000443427.1
estrogen receptor 1
chr3_+_8543533 1.40 ENST00000454244.1
LIM and cysteine-rich domains 1
chr22_-_24641027 1.40 ENST00000398292.3
ENST00000263112.7
ENST00000418439.2
ENST00000424217.1
ENST00000327365.4
gamma-glutamyltransferase 5
chr8_+_102504651 1.40 ENST00000251808.3
ENST00000521085.1
grainyhead-like 2 (Drosophila)
chr1_+_223101757 1.39 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr1_+_196743912 1.38 ENST00000367425.4
complement factor H-related 3
chr6_-_85474219 1.37 ENST00000369663.5
T-box 18
chr12_-_56106060 1.35 ENST00000452168.2
integrin, alpha 7
chr2_+_69240511 1.35 ENST00000409349.3
anthrax toxin receptor 1
chr19_+_4153598 1.34 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
cAMP responsive element binding protein 3-like 3
chr8_+_102504979 1.34 ENST00000395927.1
grainyhead-like 2 (Drosophila)
chr3_+_111630451 1.33 ENST00000495180.1
pleckstrin homology-like domain, family B, member 2
chr16_-_15950868 1.33 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
myosin, heavy chain 11, smooth muscle
chr6_+_43738444 1.32 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
vascular endothelial growth factor A
chr13_-_28896641 1.32 ENST00000543394.1
fms-related tyrosine kinase 1
chr2_+_69240415 1.32 ENST00000409829.3
anthrax toxin receptor 1
chr7_-_22259845 1.29 ENST00000420196.1
Rap guanine nucleotide exchange factor (GEF) 5
chr1_+_207277590 1.29 ENST00000367070.3
complement component 4 binding protein, alpha
chr8_-_13372395 1.28 ENST00000276297.4
ENST00000511869.1
deleted in liver cancer 1
chr6_+_152128686 1.27 ENST00000206249.3
estrogen receptor 1
chr1_+_196743943 1.23 ENST00000471440.2
ENST00000391985.3
complement factor H-related 3
chr9_+_133305669 1.23 ENST00000302481.1
hemicentin 2
chr15_+_101420028 1.22 ENST00000557963.1
ENST00000346623.6
aldehyde dehydrogenase 1 family, member A3
chr3_+_112930373 1.22 ENST00000498710.1
BOC cell adhesion associated, oncogene regulated
chr2_+_177015950 1.21 ENST00000306324.3
homeobox D4
chr6_+_12007897 1.19 ENST00000437559.1
RP11-456H18.2
chr5_+_78985673 1.19 ENST00000446378.2
cardiomyopathy associated 5
chr4_+_77356248 1.18 ENST00000296043.6
shroom family member 3
chr3_+_153839149 1.18 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr19_-_46476791 1.17 ENST00000263257.5
neuro-oncological ventral antigen 2
chr1_-_53387386 1.17 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
enoyl CoA hydratase domain containing 2
chr3_+_8543561 1.15 ENST00000397386.3
LIM and cysteine-rich domains 1
chr14_-_95236551 1.15 ENST00000238558.3
goosecoid homeobox
chr3_-_126373929 1.14 ENST00000523403.1
ENST00000524230.2
thioredoxin reductase 3
chr12_-_94673956 1.14 ENST00000551941.1
Uncharacterized protein
chr14_-_90085458 1.13 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr17_+_1958388 1.13 ENST00000399849.3
hypermethylated in cancer 1
chr2_+_18059906 1.11 ENST00000304101.4
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr1_-_53387352 1.11 ENST00000541281.1
enoyl CoA hydratase domain containing 2
chr5_+_34656569 1.11 ENST00000428746.2
retinoic acid induced 14
chr3_+_8543393 1.10 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LIM and cysteine-rich domains 1
chr2_+_27371866 1.08 ENST00000296096.5
transcription factor 23
chr12_+_54447637 1.08 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr13_-_46679144 1.04 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr13_-_46679185 1.03 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr16_-_79804198 1.02 ENST00000568389.1
RP11-345M22.2
chr1_+_61869748 1.02 ENST00000357977.5
nuclear factor I/A
chr6_+_142623758 1.02 ENST00000541199.1
ENST00000435011.2
G protein-coupled receptor 126
chr11_+_66624527 1.01 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr19_+_2977444 1.01 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr1_+_43148625 1.01 ENST00000436427.1
Y box binding protein 1
chr8_-_93115445 1.01 ENST00000523629.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_+_128399002 1.01 ENST00000493278.1
calumenin
chr4_+_100495864 1.00 ENST00000265517.5
ENST00000422897.2
microsomal triglyceride transfer protein
chr1_-_47407111 0.99 ENST00000371904.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chrX_-_15619076 0.97 ENST00000252519.3
angiotensin I converting enzyme 2
chr14_+_21492331 0.97 ENST00000533984.1
ENST00000532213.2
AL161668.5
chr5_-_112630598 0.95 ENST00000302475.4
mutated in colorectal cancers
chr11_+_118478313 0.95 ENST00000356063.5
pleckstrin homology-like domain, family B, member 1
chr3_-_138665969 0.95 ENST00000330315.3
forkhead box L2
chr2_+_135596106 0.94 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr19_-_39322497 0.94 ENST00000221418.4
enoyl CoA hydratase 1, peroxisomal
chr16_-_79804394 0.93 ENST00000567993.1
RP11-345M22.2
chr13_-_33859819 0.92 ENST00000336934.5
StAR-related lipid transfer (START) domain containing 13
chr4_+_5712898 0.91 ENST00000264956.6
ENST00000382674.2
Ellis van Creveld syndrome
chr7_-_99381798 0.90 ENST00000415003.1
ENST00000354593.2
cytochrome P450, family 3, subfamily A, polypeptide 4
chr17_-_31204124 0.90 ENST00000579584.1
ENST00000318217.5
ENST00000583621.1
myosin ID
chr3_-_123123407 0.89 ENST00000466617.1
adenylate cyclase 5
chr1_-_47407136 0.89 ENST00000462347.1
ENST00000371905.1
ENST00000310638.4
cytochrome P450, family 4, subfamily A, polypeptide 11
chr4_-_111119804 0.89 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chrX_+_135278908 0.88 ENST00000539015.1
ENST00000370683.1
four and a half LIM domains 1
chr2_+_242127924 0.88 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
anoctamin 7
chr6_-_138866823 0.88 ENST00000342260.5
NHS-like 1
chr5_-_158526756 0.87 ENST00000313708.6
ENST00000517373.1
early B-cell factor 1
chr1_+_47603109 0.87 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
cytochrome P450, family 4, subfamily A, polypeptide 22
chr1_-_153521714 0.87 ENST00000368713.3
S100 calcium binding protein A3
chr6_+_159590423 0.86 ENST00000297267.9
ENST00000340366.6
fibronectin type III domain containing 1
chr16_+_28874860 0.86 ENST00000545570.1
SH2B adaptor protein 1
chr9_-_4299874 0.86 ENST00000381971.3
ENST00000477901.1
GLIS family zinc finger 3
chr16_-_57520378 0.86 ENST00000340099.4
docking protein 4
chrX_+_135279179 0.86 ENST00000370676.3
four and a half LIM domains 1
chr15_+_39873268 0.86 ENST00000397591.2
ENST00000260356.5
thrombospondin 1
chr15_-_52404921 0.84 ENST00000561198.1
ENST00000260442.3
BCL2-like 10 (apoptosis facilitator)
chr3_+_157154578 0.84 ENST00000295927.3
pentraxin 3, long
chr9_+_135458021 0.82 ENST00000542090.1
BarH-like homeobox 1
chr22_+_46546406 0.82 ENST00000440343.1
ENST00000415785.1
peroxisome proliferator-activated receptor alpha
chr8_+_37654424 0.81 ENST00000315215.7
G protein-coupled receptor 124
chr11_-_64013663 0.80 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_65593784 0.80 ENST00000443619.2
sprouty-related, EVH1 domain containing 2
chr5_+_140810132 0.80 ENST00000252085.3
protocadherin gamma subfamily A, 12
chr8_-_101733794 0.78 ENST00000523555.1
poly(A) binding protein, cytoplasmic 1
chr11_-_111783595 0.77 ENST00000528628.1
crystallin, alpha B
chr17_+_4802713 0.75 ENST00000521575.1
ENST00000381365.3
chromosome 17 open reading frame 107
chr6_-_138893661 0.75 ENST00000427025.2
NHS-like 1
chr6_+_152128810 0.75 ENST00000406599.1
estrogen receptor 1
chr11_+_4664650 0.74 ENST00000396952.5
olfactory receptor, family 51, subfamily E, member 1
chr14_+_21498360 0.74 ENST00000321760.6
ENST00000460647.2
ENST00000530140.2
ENST00000472458.1
tubulin polymerization-promoting protein family member 2
chr3_-_100566492 0.73 ENST00000528490.1
ABI family, member 3 (NESH) binding protein
chr3_-_171489085 0.73 ENST00000418087.1
phospholipase D1, phosphatidylcholine-specific
chr5_+_3596168 0.73 ENST00000302006.3
iroquois homeobox 1
chr2_-_220083076 0.73 ENST00000295750.4
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr4_+_5712942 0.73 ENST00000509451.1
Ellis van Creveld syndrome
chr1_+_196857144 0.73 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr3_+_188817891 0.72 ENST00000412373.1
tumor protein p63 regulated 1
chrX_+_38420623 0.72 ENST00000378482.2
tetraspanin 7
chr16_+_83986827 0.72 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr2_-_89266286 0.71 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_-_158732340 0.71 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
activin A receptor, type I
chrX_+_9880412 0.69 ENST00000418909.2
shroom family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0009956 radial pattern formation(GO:0009956)
1.4 4.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.1 2.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.7 6.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.7 0.7 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.7 2.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.7 5.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.7 4.7 GO:0002933 lipid hydroxylation(GO:0002933)
0.7 9.9 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 4.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.6 3.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.6 1.7 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.5 2.7 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.5 3.2 GO:0006789 bilirubin conjugation(GO:0006789)
0.5 2.6 GO:0003095 pressure natriuresis(GO:0003095)
0.5 1.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.5 2.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.5 1.5 GO:2000974 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.5 1.4 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.5 1.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.4 1.3 GO:1903570 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.4 0.9 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.6 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.4 2.7 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.4 1.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.4 1.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.4 2.5 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.4 1.8 GO:0038190 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.4 1.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.3 0.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 3.8 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.3 0.9 GO:0008057 eye pigment granule organization(GO:0008057)
0.3 6.1 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 1.2 GO:0060166 olfactory pit development(GO:0060166)
0.3 0.9 GO:0003032 detection of oxygen(GO:0003032)
0.3 5.2 GO:0060056 mammary gland involution(GO:0060056)
0.3 2.9 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 1.9 GO:0097475 motor neuron migration(GO:0097475)
0.3 1.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 1.8 GO:0008218 bioluminescence(GO:0008218)
0.2 1.7 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 0.7 GO:0072086 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.2 0.2 GO:0070585 protein localization to mitochondrion(GO:0070585)
0.2 0.7 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 1.5 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.2 3.1 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.2 0.6 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.9 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.2 0.6 GO:0014736 negative regulation of muscle atrophy(GO:0014736) response to injury involved in regulation of muscle adaptation(GO:0014876)
0.2 3.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 6.7 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 2.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 2.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 2.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 1.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 3.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.2 0.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.2 0.6 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.4 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.1 0.4 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.4 GO:1902356 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 3.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.1 2.3 GO:1904261 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 0.3 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 1.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.9 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 0.9 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.9 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 1.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 1.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 2.8 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.1 0.6 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.3 GO:0061009 common bile duct development(GO:0061009)
0.1 1.0 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0039003 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 1.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 2.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0007518 myoblast fate determination(GO:0007518)
0.1 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.5 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 2.9 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 1.2 GO:0045176 apical protein localization(GO:0045176)
0.1 0.9 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 0.5 GO:0001878 response to yeast(GO:0001878)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 9.2 GO:0030449 regulation of complement activation(GO:0030449)
0.1 1.0 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.3 GO:0097501 stress response to metal ion(GO:0097501)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.1 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 1.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 4.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.4 GO:0060356 leucine import(GO:0060356)
0.1 4.2 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.9 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.2 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.0 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 1.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.8 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.0 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 1.7 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of terminal mannose on C branch(GO:0036510) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.6 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0035803 egg coat formation(GO:0035803)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.3 GO:0072719 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 1.8 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 2.2 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.7 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 5.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672) positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 2.7 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.3 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 1.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:2000987 general adaptation syndrome(GO:0051866) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0021678 third ventricle development(GO:0021678)
0.0 1.1 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 2.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.1 GO:0072233 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.0 0.2 GO:0044539 adiponectin-activated signaling pathway(GO:0033211) long-chain fatty acid import(GO:0044539)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.9 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.6 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.7 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.2 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.0 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 1.9 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0016236 macroautophagy(GO:0016236)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0005595 collagen type XII trimer(GO:0005595)
0.7 9.9 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6 1.8 GO:0043257 laminin-8 complex(GO:0043257)
0.3 1.6 GO:0005602 complement component C1 complex(GO:0005602)
0.3 5.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 3.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 2.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.2 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.2 1.8 GO:0097443 sorting endosome(GO:0097443)
0.2 2.4 GO:0030478 actin cap(GO:0030478)
0.2 6.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 2.3 GO:0045180 basal cortex(GO:0045180)
0.1 1.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 4.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 1.6 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.2 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 13.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.9 GO:0005921 gap junction(GO:0005921)
0.0 0.5 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 10.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 8.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 3.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.6 GO:0008305 integrin complex(GO:0008305)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 4.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 1.1 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 8.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.1 GO:0045095 keratin filament(GO:0045095)
0.0 1.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 2.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.6 4.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.5 2.6 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.5 1.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 3.8 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.4 3.6 GO:0043237 laminin-1 binding(GO:0043237)
0.4 1.5 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.3 1.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 0.9 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.3 1.8 GO:0050692 DBD domain binding(GO:0050692)
0.3 2.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.3 2.5 GO:0001849 complement component C1q binding(GO:0001849)
0.2 0.7 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 12.0 GO:0001972 retinoic acid binding(GO:0001972)
0.2 3.0 GO:0051525 NFAT protein binding(GO:0051525)
0.2 1.8 GO:0098821 BMP receptor activity(GO:0098821)
0.2 0.7 GO:0052852 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.2 1.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 0.6 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.2 0.8 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.6 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2 3.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 0.7 GO:0016361 activin receptor activity, type I(GO:0016361)
0.2 0.5 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.9 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.2 5.0 GO:0031005 filamin binding(GO:0031005)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 2.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.4 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 9.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.6 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0004335 galactokinase activity(GO:0004335)
0.1 2.1 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 1.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 2.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.4 GO:0089720 caspase binding(GO:0089720)
0.1 3.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 8.3 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.4 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.2 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.5 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.4 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 6.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 1.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 0.5 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.7 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 0.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0004802 transketolase activity(GO:0004802)
0.1 4.9 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 1.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.4 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.7 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 4.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 2.7 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 12.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.6 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.5 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0005548 phospholipid transporter activity(GO:0005548)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.2 16.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 9.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 10.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 5.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 4.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 2.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 2.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.6 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 5.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 5.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 9.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 3.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.9 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 4.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 4.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 5.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 5.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 14.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 8.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 10.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 2.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 5.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 5.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 3.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism