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Illumina Body Map 2

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Results for NR1I3

Z-value: 0.50

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207986_1612080000.261.5e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_57766075 2.54 ENST00000371030.2
ZNF831
zinc finger protein 831
chr10_-_73848764 1.69 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr13_-_20806440 1.53 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr22_+_42372764 1.39 ENST00000396426.3
ENST00000406029.1
SEPT3
septin 3
chr7_-_31380502 1.30 ENST00000297142.3
NEUROD6
neuronal differentiation 6
chr1_+_153330322 1.23 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr11_+_105480740 1.22 ENST00000393125.2
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr4_-_57524061 1.15 ENST00000508121.1
HOPX
HOP homeobox
chr12_-_75601778 1.12 ENST00000550433.1
ENST00000548513.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr14_-_50506589 1.06 ENST00000553914.2
RP11-58E21.3
RP11-58E21.3
chr1_-_235116495 1.05 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr8_+_11351876 1.01 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr5_+_156712372 1.01 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr5_-_39270725 0.85 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr22_+_39493207 0.83 ENST00000348946.4
ENST00000442487.3
ENST00000421988.2
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr14_+_22748980 0.81 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr11_+_105480770 0.80 ENST00000531986.1
GRIA4
glutamate receptor, ionotropic, AMPA 4
chr5_-_176937351 0.78 ENST00000377112.4
ENST00000501403.2
ENST00000312943.6
DOK3
docking protein 3
chr1_-_205290865 0.78 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr20_-_44007014 0.72 ENST00000372726.3
ENST00000537995.1
TP53TG5
TP53 target 5
chr4_+_37245799 0.71 ENST00000309447.5
KIAA1239
KIAA1239
chr12_-_54779511 0.71 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr6_+_32407619 0.70 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr11_-_83393303 0.68 ENST00000398304.1
ENST00000420775.2
DLG2
discs, large homolog 2 (Drosophila)
chr22_+_39493268 0.67 ENST00000401756.1
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr6_+_108487245 0.60 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr19_-_49140609 0.59 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr12_-_53729525 0.51 ENST00000303846.3
SP7
Sp7 transcription factor
chr16_+_58535372 0.51 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr13_-_95131923 0.51 ENST00000377028.5
ENST00000446125.1
DCT
dopachrome tautomerase
chr5_-_176936817 0.51 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr11_-_88799113 0.50 ENST00000393294.3
GRM5
glutamate receptor, metabotropic 5
chr3_+_52350335 0.50 ENST00000420323.2
DNAH1
dynein, axonemal, heavy chain 1
chr3_-_108476231 0.50 ENST00000295755.6
RETNLB
resistin like beta
chrX_-_39186610 0.49 ENST00000429281.1
ENST00000448597.1
RP11-265P11.2
RP11-265P11.2
chr16_-_4465886 0.49 ENST00000539968.1
CORO7
coronin 7
chr19_-_9968816 0.48 ENST00000590841.1
OLFM2
olfactomedin 2
chr11_-_83878041 0.46 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_32210275 0.46 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr1_+_154378049 0.46 ENST00000512471.1
IL6R
interleukin 6 receptor
chr7_+_143079000 0.46 ENST00000392910.2
ZYX
zyxin
chr3_-_116163830 0.45 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr17_-_53499218 0.45 ENST00000571578.1
MMD
monocyte to macrophage differentiation-associated
chr4_-_82136114 0.44 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chr1_+_43803475 0.44 ENST00000372470.3
ENST00000413998.2
MPL
myeloproliferative leukemia virus oncogene
chr14_+_22988947 0.43 ENST00000390513.1
TRAJ24
T cell receptor alpha joining 24
chrX_-_110655391 0.43 ENST00000356915.2
ENST00000356220.3
DCX
doublecortin
chr11_-_71781096 0.42 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_71753188 0.40 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr11_-_104480019 0.40 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr9_+_75766763 0.39 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr14_-_22005062 0.38 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr12_-_118810688 0.38 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr7_-_56160666 0.38 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr3_-_71802760 0.38 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr17_-_10701241 0.36 ENST00000578763.1
LINC00675
long intergenic non-protein coding RNA 675
chr11_-_61124266 0.36 ENST00000539890.1
CYB561A3
cytochrome b561 family, member A3
chr19_-_49140692 0.36 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr14_-_22005018 0.35 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr2_-_69180083 0.34 ENST00000328895.4
GKN2
gastrokine 2
chr1_-_225616515 0.34 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr18_+_61557781 0.33 ENST00000443281.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr9_-_35361262 0.32 ENST00000599954.1
AL160274.1
HCG17281; PRO0038; Uncharacterized protein
chr9_-_114937676 0.32 ENST00000374270.3
SUSD1
sushi domain containing 1
chr1_+_145516252 0.32 ENST00000369306.3
PEX11B
peroxisomal biogenesis factor 11 beta
chr1_+_154377669 0.31 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr17_-_53499310 0.31 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr18_-_19283649 0.31 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr8_-_143833918 0.30 ENST00000359228.3
LYPD2
LY6/PLAUR domain containing 2
chr12_+_100594557 0.30 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr7_-_56160625 0.29 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr16_+_30710462 0.29 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr1_+_145516560 0.29 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr10_-_50396425 0.28 ENST00000374148.1
C10orf128
chromosome 10 open reading frame 128
chr10_+_80027085 0.28 ENST00000415959.1
LINC00595
long intergenic non-protein coding RNA 595
chr9_-_125148928 0.27 ENST00000600713.1
AL162424.1
Uncharacterized protein
chr19_-_44306590 0.27 ENST00000377950.3
LYPD5
LY6/PLAUR domain containing 5
chr6_-_127780510 0.27 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr1_+_59250815 0.26 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr2_-_69180012 0.26 ENST00000481498.1
GKN2
gastrokine 2
chr4_+_70894130 0.25 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr18_-_19284724 0.25 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr11_+_63137251 0.25 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr15_-_42343388 0.24 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr5_+_139055055 0.24 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr14_+_100070869 0.24 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr1_+_44401479 0.23 ENST00000438616.3
ARTN
artemin
chr7_+_101460882 0.23 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr6_-_34113856 0.21 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr3_-_116164306 0.21 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr14_-_22005197 0.21 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr9_+_34179003 0.21 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1
ubiquitin associated protein 1
chr4_-_170897045 0.20 ENST00000508313.1
RP11-205M3.3
RP11-205M3.3
chr11_-_82611448 0.19 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr1_-_21625486 0.19 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr10_-_50396407 0.19 ENST00000374153.2
ENST00000374151.3
C10orf128
chromosome 10 open reading frame 128
chr11_+_62556596 0.18 ENST00000526546.1
TMEM179B
transmembrane protein 179B
chr6_+_36097992 0.18 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr19_-_6604094 0.18 ENST00000597430.2
CD70
CD70 molecule
chr15_+_43985084 0.17 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr17_-_33390667 0.16 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr15_+_85523671 0.16 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr12_+_49208234 0.16 ENST00000540990.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr8_-_53626974 0.16 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chrX_+_118602363 0.16 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr9_+_5450503 0.15 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chrX_+_69674943 0.14 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr5_+_139055021 0.14 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr16_+_67906919 0.13 ENST00000358933.5
EDC4
enhancer of mRNA decapping 4
chr16_+_67280799 0.13 ENST00000566345.2
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr14_+_21525981 0.12 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr14_+_22977587 0.12 ENST00000390504.1
TRAJ33
T cell receptor alpha joining 33
chr2_-_241075706 0.12 ENST00000607357.1
ENST00000307266.3
MYEOV2
myeloma overexpressed 2
chr1_+_26036093 0.11 ENST00000374329.1
MAN1C1
mannosidase, alpha, class 1C, member 1
chr1_+_160097462 0.10 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr11_-_59950519 0.10 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr1_+_32930647 0.10 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chrX_-_153583257 0.10 ENST00000438732.1
FLNA
filamin A, alpha
chr20_-_62339315 0.09 ENST00000440854.1
ENST00000607873.1
ARFRP1
ADP-ribosylation factor related protein 1
chr19_+_58919992 0.09 ENST00000306910.4
ENST00000598901.1
ENST00000593920.1
ENST00000596281.1
ZNF584
zinc finger protein 584
chr12_+_57998400 0.08 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr9_-_80646374 0.08 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr20_-_62339190 0.07 ENST00000324228.2
ENST00000609142.1
ARFRP1
ADP-ribosylation factor related protein 1
chr10_+_47658234 0.07 ENST00000447511.2
ENST00000537271.1
ANTXRL
anthrax toxin receptor-like
chr17_+_62503073 0.07 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chr2_-_86790593 0.06 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr1_+_113217043 0.06 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr15_+_43885252 0.06 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr9_+_37486005 0.05 ENST00000377792.3
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr20_+_62339381 0.05 ENST00000355969.6
ENST00000357119.4
ENST00000431125.1
ENST00000369967.3
ENST00000328969.5
ZGPAT
zinc finger, CCCH-type with G patch domain
chr12_+_53693812 0.05 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr2_-_86790472 0.04 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr11_+_933555 0.04 ENST00000534485.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr19_+_58920102 0.04 ENST00000599238.1
ENST00000322834.7
ZNF584
zinc finger protein 584
chr1_-_1690014 0.03 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr1_-_20755140 0.03 ENST00000418743.1
ENST00000426428.1
RP4-749H3.1
long intergenic non-protein coding RNA 1141
chr14_+_53173910 0.02 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr6_+_96969672 0.02 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr19_+_7562431 0.01 ENST00000361664.2
C19orf45
chromosome 19 open reading frame 45
chr14_+_53173890 0.01 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 0.8 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.5 GO:0070383 DNA cytosine deamination(GO:0070383)
0.2 0.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.1 0.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.4 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.1 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 1.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.4 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.5 GO:1902938 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.8 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.1 1.0 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 0.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.1 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:1903280 negative regulation of calcium:sodium antiporter activity(GO:1903280)
0.0 1.3 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 2.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.7 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.5 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.2 GO:0015853 adenine transport(GO:0015853)
0.0 1.3 GO:0046710 GDP metabolic process(GO:0046710) receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 1.5 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 1.0 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.8 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.8 GO:0055028 cortical microtubule(GO:0055028)
0.1 0.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.2 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.9 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 1.7 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.2 1.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 2.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.4 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.5 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 1.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins