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Illumina Body Map 2
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Results for NR2F2
Z-value: 1.43
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Transcription factors associated with NR2F2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NR2F2 | hg19_v2_chr15_+_96875657_96875794 | 0.16 | 3.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of NR2F2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.0 | GO:0045124 | regulation of bone resorption(GO:0045124) |
| 0.3 | 4.3 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 3.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 3.4 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.1 | 3.1 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.4 | 3.0 | GO:0044789 | modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) |
| 0.9 | 2.7 | GO:2000854 | positive regulation of corticosterone secretion(GO:2000854) |
| 0.2 | 2.7 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.0 | 2.7 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 2.6 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.2 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 7.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 5.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 4.4 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 3.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 3.5 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 3.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 3.0 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 2.7 | GO:0030673 | axolemma(GO:0030673) |
| 0.8 | 2.5 | GO:0070703 | inner mucus layer(GO:0070702) outer mucus layer(GO:0070703) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 6.7 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.0 | 4.3 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.3 | 3.1 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.1 | 3.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 3.1 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.0 | 3.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 2.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 2.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.2 | 2.7 | GO:0043184 | vascular endothelial growth factor receptor 2 binding(GO:0043184) |
| 0.1 | 2.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 3.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 2.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 2.4 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.8 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.1 | 1.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 1.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 1.6 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.4 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 1.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.6 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 4.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 3.5 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 3.4 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.0 | 3.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 2.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.7 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.1 | 2.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 2.2 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |