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Illumina Body Map 2

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Results for OTX1

Z-value: 0.73

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_63277938-0.318.9e-02Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_33605231 2.43 ENST00000570121.2
IGHV3OR16-12
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr14_+_22409308 2.38 ENST00000390441.2
TRAV9-2
T cell receptor alpha variable 9-2
chr14_-_106967788 2.16 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr14_-_107170409 2.16 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr20_+_48884002 2.16 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr6_+_106546808 1.96 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr6_-_133055815 1.86 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr5_+_101569696 1.85 ENST00000597120.1
AC008948.1
AC008948.1
chr6_-_133055896 1.84 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr14_+_22392209 1.81 ENST00000390440.2
TRAV14DV4
T cell receptor alpha variable 14/delta variable 4
chr11_+_128563652 1.79 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr1_-_160832490 1.76 ENST00000322302.7
ENST00000368033.3
CD244
CD244 molecule, natural killer cell receptor 2B4
chr14_+_102196739 1.75 ENST00000556973.1
RP11-796G6.2
Uncharacterized protein
chr19_-_47616992 1.75 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chr7_+_142364193 1.70 ENST00000390397.2
TRBV24-1
T cell receptor beta variable 24-1
chr14_-_106539557 1.68 ENST00000390599.2
IGHV1-8
immunoglobulin heavy variable 1-8
chr1_-_160832670 1.58 ENST00000368032.2
CD244
CD244 molecule, natural killer cell receptor 2B4
chr14_-_106471723 1.58 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr17_-_79623597 1.57 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr2_-_161350305 1.55 ENST00000348849.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr1_-_16539094 1.53 ENST00000270747.3
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr14_-_107131560 1.53 ENST00000390632.2
IGHV3-66
immunoglobulin heavy variable 3-66
chr2_-_160654745 1.52 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr1_-_160832642 1.50 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr14_-_107211459 1.49 ENST00000390636.2
IGHV3-73
immunoglobulin heavy variable 3-73
chr6_-_32731243 1.48 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr3_+_188664988 1.47 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr14_-_107179265 1.42 ENST00000390634.2
IGHV2-70
immunoglobulin heavy variable 2-70
chr1_+_160709076 1.37 ENST00000359331.4
ENST00000495334.1
SLAMF7
SLAM family member 7
chr19_+_55084438 1.36 ENST00000439534.1
LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr1_-_92351769 1.29 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr4_+_100737954 1.28 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr9_+_125132803 1.26 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr12_-_54071181 1.23 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr12_+_113354341 1.18 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr15_-_61521495 1.11 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr14_-_89878369 1.10 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr17_-_8770956 1.10 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr11_+_130029457 1.10 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr11_-_104817919 1.08 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr11_-_67275542 1.08 ENST00000531506.1
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr1_+_174844645 1.08 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr19_-_3761673 1.07 ENST00000316757.3
APBA3
amyloid beta (A4) precursor protein-binding, family A, member 3
chr2_-_190448118 1.04 ENST00000440626.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_+_221054411 1.02 ENST00000427693.1
HLX
H2.0-like homeobox
chr5_-_39425290 1.02 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr17_-_36981556 1.00 ENST00000536127.1
ENST00000225428.5
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr17_-_26876350 0.99 ENST00000470125.1
UNC119
unc-119 homolog (C. elegans)
chr5_-_39425222 0.99 ENST00000320816.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_54988448 0.98 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr1_+_40840320 0.95 ENST00000372708.1
SMAP2
small ArfGAP2
chr4_-_70626314 0.93 ENST00000510821.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr10_-_104211294 0.93 ENST00000239125.1
C10orf95
chromosome 10 open reading frame 95
chr6_+_33359582 0.90 ENST00000450504.1
KIFC1
kinesin family member C1
chr19_+_52255261 0.89 ENST00000600258.1
FPR2
formyl peptide receptor 2
chr11_-_67276100 0.89 ENST00000301488.3
CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr3_+_138340049 0.87 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr7_+_120702819 0.86 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr19_+_35940486 0.86 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr3_+_138340067 0.85 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr16_-_29875057 0.85 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chrX_+_100645812 0.83 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr11_-_65626797 0.81 ENST00000525451.2
CFL1
cofilin 1 (non-muscle)
chrX_+_2670153 0.76 ENST00000509484.2
XG
Xg blood group
chr4_+_108815402 0.75 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr17_-_34329084 0.75 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chr16_+_58033450 0.73 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr6_+_26251835 0.73 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr21_-_30047095 0.72 ENST00000452028.1
ENST00000433310.2
AF131217.1
AF131217.1
chr5_+_177631497 0.72 ENST00000358344.3
HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr14_-_24911448 0.71 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr17_+_41158742 0.71 ENST00000415816.2
ENST00000438323.2
IFI35
interferon-induced protein 35
chr11_+_8704748 0.71 ENST00000526562.1
ENST00000525981.1
RPL27A
ribosomal protein L27a
chr6_+_35420091 0.70 ENST00000229769.2
FANCE
Fanconi anemia, complementation group E
chr1_-_53608249 0.70 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr8_-_125577940 0.67 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr11_-_78052923 0.67 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr12_+_6603253 0.67 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr10_+_114133773 0.67 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr3_+_42544084 0.66 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1
vasoactive intestinal peptide receptor 1
chr19_+_16308711 0.65 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr1_-_206288647 0.65 ENST00000331555.5
C1orf186
chromosome 1 open reading frame 186
chr5_+_96038554 0.63 ENST00000508197.1
CAST
calpastatin
chr6_-_34393825 0.63 ENST00000605528.1
ENST00000326199.8
RPS10-NUDT3
RPS10
RPS10-NUDT3 readthrough
ribosomal protein S10
chr4_-_83769996 0.62 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr17_-_4689649 0.61 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr9_-_95244781 0.59 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr2_-_111230393 0.59 ENST00000447537.2
ENST00000413601.2
LIMS3L
LIMS3L
LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein
LIM and senescent cell antigen-like domains 3-like
chr16_-_29874462 0.59 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr2_-_85637459 0.58 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr1_+_222913009 0.58 ENST00000456298.1
FAM177B
family with sequence similarity 177, member B
chr2_-_96192450 0.58 ENST00000609975.1
RP11-440D17.3
RP11-440D17.3
chr5_+_135496675 0.57 ENST00000507637.1
SMAD5
SMAD family member 5
chr3_-_156878540 0.57 ENST00000461804.1
CCNL1
cyclin L1
chr12_+_1099675 0.57 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr1_-_161039753 0.57 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr5_-_59783882 0.56 ENST00000505507.2
ENST00000502484.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr5_+_96038476 0.56 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
CAST
calpastatin
chr6_-_137539651 0.56 ENST00000543628.1
IFNGR1
interferon gamma receptor 1
chr3_+_136649311 0.55 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr21_+_33671264 0.55 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr15_+_42787452 0.55 ENST00000249647.3
SNAP23
synaptosomal-associated protein, 23kDa
chr17_-_71223839 0.54 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr7_-_38293030 0.53 ENST00000390333.1
TRGJ2
T cell receptor gamma joining 2
chr7_-_38309141 0.53 ENST00000390337.1
TRGJ1
T cell receptor gamma joining 1
chr7_+_140103842 0.53 ENST00000495590.1
ENST00000275874.5
ENST00000537763.1
RAB19
RAB19, member RAS oncogene family
chr8_-_79717750 0.52 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr7_+_30589829 0.52 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr16_-_29874211 0.52 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr7_-_100239132 0.51 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr9_+_91605778 0.51 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
C9orf47
chromosome 9 open reading frame 47
chr3_-_69062790 0.51 ENST00000540955.1
ENST00000456376.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr7_+_16700806 0.50 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr11_-_65626753 0.50 ENST00000526975.1
ENST00000531413.1
CFL1
cofilin 1 (non-muscle)
chr19_+_16308659 0.48 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr20_+_3052264 0.48 ENST00000217386.2
OXT
oxytocin/neurophysin I prepropeptide
chrX_+_149861836 0.47 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr12_+_20963647 0.46 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr2_+_110656005 0.46 ENST00000437679.2
LIMS3
LIM and senescent cell antigen-like domains 3
chr6_+_96025341 0.46 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr2_+_204103663 0.46 ENST00000356079.4
ENST00000429815.2
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr6_+_42018614 0.45 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr3_+_151451707 0.44 ENST00000356517.3
AADACL2
arylacetamide deacetylase-like 2
chr4_-_112993808 0.43 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr1_+_241695670 0.41 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr14_-_65769392 0.41 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr6_-_9939552 0.41 ENST00000460363.2
OFCC1
orofacial cleft 1 candidate 1
chr2_-_201936302 0.40 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_-_216596738 0.39 ENST00000307340.3
ENST00000366943.2
ENST00000366942.3
USH2A
Usher syndrome 2A (autosomal recessive, mild)
chr1_+_241695424 0.39 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_+_15728003 0.39 ENST00000442176.1
AC005550.4
AC005550.4
chr6_-_144416737 0.39 ENST00000367569.2
SF3B5
splicing factor 3b, subunit 5, 10kDa
chrX_-_109561294 0.38 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr12_+_20963632 0.37 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_+_170501270 0.37 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr1_-_146696901 0.37 ENST00000369272.3
ENST00000441068.2
FMO5
flavin containing monooxygenase 5
chr3_-_45017609 0.36 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3
zinc finger, DHHC-type containing 3
chrX_-_100307043 0.36 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
TRMT2B
tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr2_+_204103733 0.36 ENST00000443941.1
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr4_-_122744998 0.36 ENST00000274026.5
CCNA2
cyclin A2
chr6_+_140175987 0.36 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr19_+_10381769 0.36 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr1_+_74701062 0.36 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr3_+_111393659 0.36 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr11_-_62420757 0.35 ENST00000330574.2
INTS5
integrator complex subunit 5
chr3_-_69062764 0.35 ENST00000295571.5
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr8_-_33370607 0.35 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chr16_-_8962200 0.35 ENST00000562843.1
ENST00000561530.1
ENST00000396593.2
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr15_+_57540230 0.35 ENST00000559703.1
TCF12
transcription factor 12
chr15_-_34629922 0.35 ENST00000559484.1
ENST00000354181.3
ENST00000558589.1
ENST00000458406.2
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chrX_+_53123314 0.35 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr10_-_28571015 0.34 ENST00000375719.3
ENST00000375732.1
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr3_-_141747950 0.34 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_17448348 0.34 ENST00000324894.8
ENST00000358792.7
ENST00000600625.1
GTPBP3
GTP binding protein 3 (mitochondrial)
chr9_+_128509624 0.33 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr19_-_10530784 0.32 ENST00000593124.1
CDC37
cell division cycle 37
chr3_+_11314099 0.31 ENST00000446450.2
ENST00000354956.5
ENST00000354449.3
ENST00000419112.1
ATG7
autophagy related 7
chr3_+_111393501 0.30 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr5_-_81574160 0.30 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23
ribosomal protein S23
chr3_-_69129501 0.30 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
UBA3
ubiquitin-like modifier activating enzyme 3
chr16_-_58163262 0.30 ENST00000565880.1
C16orf80
chromosome 16 open reading frame 80
chr9_-_35665165 0.30 ENST00000343259.3
ENST00000378387.3
ARHGEF39
Rho guanine nucleotide exchange factor (GEF) 39
chr19_+_41903709 0.29 ENST00000542943.1
ENST00000457836.2
BCKDHA
branched chain keto acid dehydrogenase E1, alpha polypeptide
chr16_-_21868978 0.29 ENST00000357370.5
ENST00000451409.1
ENST00000341400.7
ENST00000518761.4
NPIPB4
nuclear pore complex interacting protein family, member B4
chrX_+_133507283 0.28 ENST00000370803.3
PHF6
PHD finger protein 6
chr6_-_28806779 0.28 ENST00000457253.1
XXbac-BPG308K3.5
XXbac-BPG308K3.5
chr6_-_131211534 0.28 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr11_-_6191638 0.28 ENST00000530810.1
OR52B2
olfactory receptor, family 52, subfamily B, member 2
chr16_-_57880439 0.27 ENST00000565684.1
KIFC3
kinesin family member C3
chr13_-_43566301 0.27 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr1_+_28764653 0.27 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr1_-_154928562 0.27 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr16_-_58163299 0.25 ENST00000262498.3
C16orf80
chromosome 16 open reading frame 80
chr16_-_21452040 0.25 ENST00000521589.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr21_-_43816052 0.25 ENST00000398405.1
TMPRSS3
transmembrane protease, serine 3
chr1_-_151300160 0.25 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr1_-_36930012 0.24 ENST00000373116.5
MRPS15
mitochondrial ribosomal protein S15
chr1_+_184020811 0.24 ENST00000361641.1
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr1_+_45805342 0.23 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr8_-_56986768 0.23 ENST00000523936.1
RPS20
ribosomal protein S20
chrX_-_49089771 0.23 ENST00000376251.1
ENST00000323022.5
ENST00000376265.2
CACNA1F
calcium channel, voltage-dependent, L type, alpha 1F subunit
chr1_+_150293973 0.22 ENST00000414970.2
ENST00000543398.1
PRPF3
pre-mRNA processing factor 3
chr19_-_41903161 0.22 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chr12_-_4754318 0.22 ENST00000536414.1
AKAP3
A kinase (PRKA) anchor protein 3
chr5_-_77072085 0.22 ENST00000518338.2
ENST00000520039.1
ENST00000306388.6
ENST00000520361.1
TBCA
tubulin folding cofactor A
chr14_+_21458127 0.21 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17
methyltransferase like 17
chr1_+_184020830 0.21 ENST00000533373.1
ENST00000423085.2
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr9_-_116172946 0.21 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr8_+_55528627 0.20 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr11_-_111957451 0.20 ENST00000504148.2
ENST00000541231.1
TIMM8B
translocase of inner mitochondrial membrane 8 homolog B (yeast)
chr2_-_47403642 0.20 ENST00000456319.1
ENST00000409563.1
ENST00000272298.7
CALM2
calmodulin 2 (phosphorylase kinase, delta)
chr3_-_69062742 0.20 ENST00000424374.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr12_+_7864021 0.20 ENST00000345088.2
DPPA3
developmental pluripotency associated 3
chr1_+_117910047 0.19 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr10_-_31996316 0.19 ENST00000433770.1
RP11-472N13.3
RP11-472N13.3
chr17_-_39324424 0.19 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr11_+_119205222 0.19 ENST00000311413.4
RNF26
ring finger protein 26
chr16_-_29415350 0.18 ENST00000524087.1
NPIPB11
nuclear pore complex interacting protein family, member B11
chr3_+_145782358 0.18 ENST00000422482.1
AC107021.1
HCG1786590; PRO2533; Uncharacterized protein
chr2_-_112642267 0.17 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.7 2.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.3 1.0 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 2.0 GO:0035026 leading edge cell differentiation(GO:0035026)
0.3 0.9 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.3 1.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.2 1.0 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 2.0 GO:2000035 regulation of stem cell division(GO:2000035)
0.2 3.7 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 1.3 GO:2000769 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.2 0.6 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.5 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.2 1.1 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.4 GO:0039521 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 1.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.3 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.3 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.7 GO:0030035 microspike assembly(GO:0030035)
0.1 0.6 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.4 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 7.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.5 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 0.4 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 2.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.3 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.1 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0044725 chromatin reprogramming in the zygote(GO:0044725)
0.0 5.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 1.1 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0 0.5 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 1.1 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 1.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.7 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 2.5 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 3.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 4.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.4 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.2 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.5 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.8 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.9 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.7 GO:0071346 cellular response to interferon-gamma(GO:0071346)
0.0 0.3 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.7 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3 1.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 2.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0002139 stereocilia coupling link(GO:0002139)
0.1 7.0 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 1.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.7 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.5 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.7 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.0 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 5.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.6 3.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 1.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.3 1.0 GO:0097689 iron channel activity(GO:0097689)
0.3 1.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 0.5 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.2 1.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.7 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 4.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.9 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 1.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 7.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 1.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.1 1.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 2.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.9 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 1.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 8.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 1.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 2.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 1.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 2.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 2.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification