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Illumina Body Map 2

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Results for PRDM4

Z-value: 0.59

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Transcription factors associated with PRDM4

Gene Symbol Gene ID Gene Info
ENSG00000110851.7 PR/SET domain 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PRDM4hg19_v2_chr12_-_108154925_1081549450.412.0e-02Click!

Activity profile of PRDM4 motif

Sorted Z-values of PRDM4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_73072534 2.42 ENST00000429829.1
X inactive specific transcript (non-protein coding)
chr9_-_127263265 1.73 ENST00000373587.3
nuclear receptor subfamily 5, group A, member 1
chr17_+_42634844 1.26 ENST00000315323.3
frizzled family receptor 2
chr9_-_16727978 1.08 ENST00000418777.1
ENST00000468187.2
basonuclin 2
chr19_+_41117770 1.05 ENST00000601032.1
latent transforming growth factor beta binding protein 4
chr1_+_55107449 1.01 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
maestro heat-like repeat family member 7
chr7_+_90893783 1.01 ENST00000287934.2
frizzled family receptor 1
chr4_+_2451700 0.77 ENST00000506607.1
Uncharacterized protein
chr1_+_6511651 0.68 ENST00000434576.1
espin
chr1_+_55107489 0.66 ENST00000395690.2
maestro heat-like repeat family member 7
chr1_-_68516393 0.56 ENST00000395201.1
DIRAS family, GTP-binding RAS-like 3
chr3_-_169381166 0.54 ENST00000486748.1
MDS1 and EVI1 complex locus
chr2_-_179343226 0.52 ENST00000434643.2
FK506 binding protein 7
chr20_-_49639631 0.51 ENST00000424171.1
ENST00000439216.1
ENST00000371571.4
potassium voltage-gated channel, subfamily G, member 1
chr19_-_49371711 0.51 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr13_+_52436111 0.51 ENST00000242819.4
coiled-coil domain containing 70
chr1_+_172502336 0.50 ENST00000263688.3
SUN domain containing ossification factor
chr8_-_135652051 0.47 ENST00000522257.1
zinc finger and AT hook domain containing
chr1_+_172502244 0.44 ENST00000610051.1
SUN domain containing ossification factor
chr2_-_179343268 0.43 ENST00000424785.2
FK506 binding protein 7
chr22_+_38864041 0.42 ENST00000216014.4
ENST00000409006.3
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr19_-_53636125 0.39 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
zinc finger protein 415
chr11_-_441964 0.36 ENST00000332826.6
anoctamin 9
chr10_+_88728189 0.35 ENST00000416348.1
adipogenesis regulatory factor
chr14_+_105953246 0.31 ENST00000392531.3
cysteine-rich protein 1 (intestinal)
chr17_+_7788104 0.29 ENST00000380358.4
chromodomain helicase DNA binding protein 3
chr1_-_43232649 0.29 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
leucine proline-enriched proteoglycan (leprecan) 1
chr19_-_35264089 0.28 ENST00000588760.1
ENST00000329285.8
ENST00000587354.2
zinc finger protein 599
chr14_+_105953204 0.28 ENST00000409393.2
cysteine-rich protein 1 (intestinal)
chr2_+_219264762 0.25 ENST00000452977.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_61569227 0.24 ENST00000266070.4
ENST00000395335.2
ENST00000266071.5
death inducer-obliterator 1
chr14_+_64565442 0.23 ENST00000553308.1
spectrin repeat containing, nuclear envelope 2
chr1_+_27114418 0.22 ENST00000078527.4
phosphatidylinositol glycan anchor biosynthesis, class V
chr5_+_102455968 0.22 ENST00000358359.3
diphosphoinositol pentakisphosphate kinase 2
chr16_+_88636875 0.21 ENST00000569435.1
zinc finger CCCH-type containing 18
chr8_+_94712752 0.20 ENST00000522324.1
ENST00000522803.1
ENST00000423990.2
family with sequence similarity 92, member A1
chr8_+_94712732 0.20 ENST00000518322.1
family with sequence similarity 92, member A1
chr22_-_39636914 0.20 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr11_+_19138670 0.20 ENST00000446113.2
ENST00000399351.3
zinc finger, DHHC-type containing 13
chr11_+_8040739 0.20 ENST00000534099.1
tubby bipartite transcription factor
chr1_+_151043070 0.19 ENST00000368918.3
ENST00000368917.1
GA binding protein transcription factor, beta subunit 2
chr7_-_23571586 0.19 ENST00000538367.1
ENST00000392502.4
ENST00000297071.4
transformer 2 alpha homolog (Drosophila)
chr2_+_219264466 0.18 ENST00000273062.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr20_-_49639612 0.17 ENST00000396017.3
ENST00000433903.1
potassium voltage-gated channel, subfamily G, member 1
chr10_-_105212141 0.17 ENST00000369788.3
calcium homeostasis modulator 2
chr6_-_8064567 0.16 ENST00000543936.1
ENST00000397457.2
biogenesis of lysosomal organelles complex-1, subunit 5, muted
chr6_+_26045603 0.16 ENST00000540144.1
histone cluster 1, H3c
chr5_-_180688105 0.16 ENST00000327767.4
tripartite motif containing 52
chr9_+_17135016 0.15 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr20_-_61569296 0.15 ENST00000370371.4
death inducer-obliterator 1
chr16_+_15068831 0.14 ENST00000535621.2
ENST00000566426.1
pyridoxal-dependent decarboxylase domain containing 1
chr8_+_81397846 0.14 ENST00000379091.4
zinc finger and BTB domain containing 10
chr5_+_102455853 0.14 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
diphosphoinositol pentakisphosphate kinase 2
chr11_+_58910295 0.14 ENST00000420244.1
family with sequence similarity 111, member A
chr16_+_15068955 0.13 ENST00000396410.4
ENST00000569715.1
ENST00000450288.2
pyridoxal-dependent decarboxylase domain containing 1
chr5_-_102455801 0.13 ENST00000508629.1
ENST00000399004.2
gypsy retrotransposon integrase 1
chr16_+_15068916 0.13 ENST00000455313.2
pyridoxal-dependent decarboxylase domain containing 1
chr19_+_42724423 0.13 ENST00000301215.3
ENST00000597945.1
zinc finger protein 526
chr4_-_83295103 0.10 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr16_+_88636789 0.10 ENST00000301011.5
ENST00000452588.2
zinc finger CCCH-type containing 18
chr1_+_27114589 0.10 ENST00000431541.1
ENST00000449950.2
ENST00000374145.1
phosphatidylinositol glycan anchor biosynthesis, class V
chr12_+_15475331 0.10 ENST00000281171.4
protein tyrosine phosphatase, receptor type, O
chr20_+_58296265 0.10 ENST00000395636.2
ENST00000361300.4
phosphatase and actin regulator 3
chr12_+_15475462 0.09 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr1_+_16865561 0.09 ENST00000601199.1
family with sequence similarity 231, member B
chr6_-_24721054 0.09 ENST00000378119.4
chromosome 6 open reading frame 62
chr20_+_62697564 0.08 ENST00000458442.1
transcription elongation factor A (SII), 2
chr15_+_74287035 0.08 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
promyelocytic leukemia
chr5_+_159343688 0.07 ENST00000306675.3
adrenoceptor alpha 1B
chr12_+_50794947 0.07 ENST00000552445.1
La ribonucleoprotein domain family, member 4
chr1_+_54359854 0.07 ENST00000361921.3
ENST00000322679.6
ENST00000532493.1
ENST00000525202.1
ENST00000524406.1
ENST00000388876.3
deiodinase, iodothyronine, type I
chr11_+_47279504 0.06 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
nuclear receptor subfamily 1, group H, member 3
chr7_+_143079000 0.05 ENST00000392910.2
zyxin
chr4_-_83295296 0.05 ENST00000507010.1
ENST00000503822.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr5_-_61031495 0.04 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr1_+_27113963 0.04 ENST00000430292.1
phosphatidylinositol glycan anchor biosynthesis, class V
chrX_+_15808569 0.04 ENST00000380308.3
ENST00000307771.7
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
chr20_+_61569463 0.04 ENST00000266069.3
GID complex subunit 8
chr9_-_70488865 0.04 ENST00000377392.5
COBW domain containing 5
chr9_+_96338647 0.03 ENST00000359246.4
PHD finger protein 2
chr8_+_91952750 0.03 ENST00000521366.1
N-terminal EF-hand calcium binding protein 1
chr7_+_143078652 0.02 ENST00000354434.4
ENST00000449423.2
zyxin
chr16_+_29823427 0.02 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
proline-rich transmembrane protein 2
chr14_+_32030582 0.02 ENST00000550649.1
ENST00000281081.7
nucleotide binding protein-like
chr16_+_29823552 0.02 ENST00000300797.6
proline-rich transmembrane protein 2
chr2_-_151905288 0.01 ENST00000409243.1
HCG1817310; Uncharacterized protein
chr12_+_69979446 0.01 ENST00000543146.2
chaperonin containing TCP1, subunit 2 (beta)

Network of associatons between targets according to the STRING database.

First level regulatory network of PRDM4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0007538 primary sex determination(GO:0007538)
0.3 1.0 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:0010360 negative regulation of anion channel activity(GO:0010360) negative regulation of chloride transport(GO:2001226)
0.1 0.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.3 GO:0003150 muscular septum morphogenesis(GO:0003150)
0.1 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.2 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.2 GO:1905176 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.7 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.3 GO:0072719 cellular response to cisplatin(GO:0072719) regulation of response to drug(GO:2001023)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 1.1 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 1.0 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.7 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0030578 PML body organization(GO:0030578)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.5 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.7 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.9 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.1 2.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 1.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)