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Illumina Body Map 2
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Results for RELA
Z-value: 1.86
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Transcription factors associated with RELA
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RELA
|
ENSG00000173039.14 | RELA proto-oncogene, NF-kB subunit |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RELA | hg19_v2_chr11_-_65430554_65430579 | 0.61 | 1.9e-04 | Click! |
Activity profile of RELA motif
Sorted Z-values of RELA motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_9913489 | 9.27 |
ENST00000228434.3
ENST00000536709.1 |
CD69
|
CD69 molecule |
| chr4_-_76944621 | 9.16 |
ENST00000306602.1
|
CXCL10
|
chemokine (C-X-C motif) ligand 10 |
| chr6_-_31550192 | 7.55 |
ENST00000429299.2
ENST00000446745.2 |
LTB
|
lymphotoxin beta (TNF superfamily, member 3) |
| chr2_-_89442621 | 6.99 |
ENST00000492167.1
|
IGKV3-20
|
immunoglobulin kappa variable 3-20 |
| chr2_+_219745020 | 6.74 |
ENST00000258411.3
|
WNT10A
|
wingless-type MMTV integration site family, member 10A |
| chr22_-_37545972 | 6.36 |
ENST00000216223.5
|
IL2RB
|
interleukin 2 receptor, beta |
| chr19_-_6591113 | 5.92 |
ENST00000423145.3
ENST00000245903.3 |
CD70
|
CD70 molecule |
| chr6_+_138188351 | 5.89 |
ENST00000421450.1
|
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr10_+_30723045 | 5.86 |
ENST00000542547.1
ENST00000415139.1 |
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr6_+_138188378 | 5.78 |
ENST00000420009.1
|
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr11_+_102188272 | 5.59 |
ENST00000532808.1
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr1_-_186649543 | 5.50 |
ENST00000367468.5
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| chr6_+_138188551 | 5.47 |
ENST00000237289.4
ENST00000433680.1 |
TNFAIP3
|
tumor necrosis factor, alpha-induced protein 3 |
| chr11_+_102188224 | 5.33 |
ENST00000263464.3
|
BIRC3
|
baculoviral IAP repeat containing 3 |
| chr10_+_30722866 | 5.16 |
ENST00000263056.1
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr4_+_74735102 | 5.14 |
ENST00000395761.3
|
CXCL1
|
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| chr4_-_74864386 | 5.11 |
ENST00000296027.4
|
CXCL5
|
chemokine (C-X-C motif) ligand 5 |
| chr10_+_104154229 | 4.89 |
ENST00000428099.1
ENST00000369966.3 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr19_+_42381173 | 4.75 |
ENST00000221972.3
|
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr11_-_5271122 | 4.37 |
ENST00000330597.3
|
HBG1
|
hemoglobin, gamma A |
| chr4_-_74904398 | 4.37 |
ENST00000296026.4
|
CXCL3
|
chemokine (C-X-C motif) ligand 3 |
| chr19_+_45504688 | 4.36 |
ENST00000221452.8
ENST00000540120.1 ENST00000505236.1 |
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B |
| chr5_-_149792295 | 4.35 |
ENST00000518797.1
ENST00000524315.1 ENST00000009530.7 ENST00000377795.3 |
CD74
|
CD74 molecule, major histocompatibility complex, class II invariant chain |
| chr22_+_37318082 | 4.18 |
ENST00000406230.1
|
CSF2RB
|
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| chr14_+_103589789 | 4.14 |
ENST00000558056.1
ENST00000560869.1 |
TNFAIP2
|
tumor necrosis factor, alpha-induced protein 2 |
| chr17_-_34207295 | 4.13 |
ENST00000463941.1
ENST00000293272.3 |
CCL5
|
chemokine (C-C motif) ligand 5 |
| chr6_+_32605134 | 4.11 |
ENST00000343139.5
ENST00000395363.1 ENST00000496318.1 |
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr19_+_42381337 | 4.08 |
ENST00000597454.1
ENST00000444740.2 |
CD79A
|
CD79a molecule, immunoglobulin-associated alpha |
| chr17_-_61776522 | 4.01 |
ENST00000582055.1
|
LIMD2
|
LIM domain containing 2 |
| chr3_+_101546827 | 4.00 |
ENST00000461724.1
ENST00000483180.1 ENST00000394054.2 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr17_-_61777090 | 3.93 |
ENST00000578061.1
|
LIMD2
|
LIM domain containing 2 |
| chr6_+_32605195 | 3.90 |
ENST00000374949.2
|
HLA-DQA1
|
major histocompatibility complex, class II, DQ alpha 1 |
| chr4_-_76957214 | 3.84 |
ENST00000306621.3
|
CXCL11
|
chemokine (C-X-C motif) ligand 11 |
| chr1_+_201979645 | 3.76 |
ENST00000367284.5
ENST00000367283.3 |
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| chr19_-_17958771 | 3.66 |
ENST00000534444.1
|
JAK3
|
Janus kinase 3 |
| chr10_+_30723105 | 3.65 |
ENST00000375322.2
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr6_+_106534192 | 3.58 |
ENST00000369091.2
ENST00000369096.4 |
PRDM1
|
PR domain containing 1, with ZNF domain |
| chr22_-_37640277 | 3.47 |
ENST00000401529.3
ENST00000249071.6 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr4_-_76928641 | 3.45 |
ENST00000264888.5
|
CXCL9
|
chemokine (C-X-C motif) ligand 9 |
| chr14_+_75988768 | 3.40 |
ENST00000286639.6
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr9_-_139927462 | 3.35 |
ENST00000314412.6
|
FUT7
|
fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
| chr14_-_35873856 | 3.34 |
ENST00000553342.1
ENST00000216797.5 ENST00000557140.1 |
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| chr16_+_50730910 | 3.26 |
ENST00000300589.2
|
NOD2
|
nucleotide-binding oligomerization domain containing 2 |
| chr7_+_22766766 | 3.26 |
ENST00000426291.1
ENST00000401651.1 ENST00000258743.5 ENST00000420258.2 ENST00000407492.1 ENST00000401630.3 ENST00000406575.1 |
IL6
|
interleukin 6 (interferon, beta 2) |
| chr17_+_16318850 | 3.21 |
ENST00000338560.7
|
TRPV2
|
transient receptor potential cation channel, subfamily V, member 2 |
| chr1_-_89738528 | 3.20 |
ENST00000343435.5
|
GBP5
|
guanylate binding protein 5 |
| chr17_+_16318909 | 3.15 |
ENST00000577397.1
|
TRPV2
|
transient receptor potential cation channel, subfamily V, member 2 |
| chr22_-_37640456 | 3.12 |
ENST00000405484.1
ENST00000441619.1 ENST00000406508.1 |
RAC2
|
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| chr14_+_75988851 | 3.08 |
ENST00000555504.1
|
BATF
|
basic leucine zipper transcription factor, ATF-like |
| chr1_-_204436344 | 3.07 |
ENST00000367184.2
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| chr19_-_47734448 | 3.07 |
ENST00000439096.2
|
BBC3
|
BCL2 binding component 3 |
| chr4_-_74964904 | 3.04 |
ENST00000508487.2
|
CXCL2
|
chemokine (C-X-C motif) ligand 2 |
| chr6_-_32636145 | 3.02 |
ENST00000399084.1
|
HLA-DQB1
|
major histocompatibility complex, class II, DQ beta 1 |
| chr6_+_135502466 | 2.99 |
ENST00000367814.4
|
MYB
|
v-myb avian myeloblastosis viral oncogene homolog |
| chr19_+_17638059 | 2.98 |
ENST00000599164.1
ENST00000449408.2 ENST00000600871.1 ENST00000599124.1 |
FAM129C
|
family with sequence similarity 129, member C |
| chr3_+_137717571 | 2.91 |
ENST00000343735.4
|
CLDN18
|
claudin 18 |
| chr6_+_31540056 | 2.91 |
ENST00000418386.2
|
LTA
|
lymphotoxin alpha |
| chr17_+_40440481 | 2.87 |
ENST00000590726.2
ENST00000452307.2 ENST00000444283.1 ENST00000588868.1 |
STAT5A
|
signal transducer and activator of transcription 5A |
| chr3_-_111852061 | 2.85 |
ENST00000488580.1
ENST00000460387.2 ENST00000484193.1 ENST00000487901.1 |
GCSAM
|
germinal center-associated, signaling and motility |
| chr2_+_228678550 | 2.85 |
ENST00000409189.3
ENST00000358813.4 |
CCL20
|
chemokine (C-C motif) ligand 20 |
| chr19_+_45251804 | 2.85 |
ENST00000164227.5
|
BCL3
|
B-cell CLL/lymphoma 3 |
| chr9_+_127054217 | 2.79 |
ENST00000394199.2
ENST00000546191.1 |
NEK6
|
NIMA-related kinase 6 |
| chr4_-_185395191 | 2.75 |
ENST00000510814.1
ENST00000507523.1 ENST00000506230.1 |
IRF2
|
interferon regulatory factor 2 |
| chr3_-_156878482 | 2.74 |
ENST00000295925.4
|
CCNL1
|
cyclin L1 |
| chr19_-_17958832 | 2.74 |
ENST00000458235.1
|
JAK3
|
Janus kinase 3 |
| chr3_-_156878540 | 2.73 |
ENST00000461804.1
|
CCNL1
|
cyclin L1 |
| chr12_+_52445191 | 2.70 |
ENST00000243050.1
ENST00000394825.1 ENST00000550763.1 ENST00000394824.2 ENST00000548232.1 ENST00000562373.1 |
NR4A1
|
nuclear receptor subfamily 4, group A, member 1 |
| chr19_-_7766991 | 2.69 |
ENST00000597921.1
ENST00000346664.5 |
FCER2
|
Fc fragment of IgE, low affinity II, receptor for (CD23) |
| chr7_-_16844611 | 2.69 |
ENST00000401412.1
ENST00000419304.2 |
AGR2
|
anterior gradient 2 |
| chrX_-_30595959 | 2.68 |
ENST00000378962.3
|
CXorf21
|
chromosome X open reading frame 21 |
| chr6_+_29691056 | 2.60 |
ENST00000414333.1
ENST00000334668.4 ENST00000259951.7 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr11_-_128392085 | 2.59 |
ENST00000526145.2
ENST00000531611.1 ENST00000319397.6 ENST00000345075.4 ENST00000535549.1 |
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| chr19_+_17638041 | 2.58 |
ENST00000601861.1
|
FAM129C
|
family with sequence similarity 129, member C |
| chr5_+_82767284 | 2.58 |
ENST00000265077.3
|
VCAN
|
versican |
| chr10_+_104155450 | 2.57 |
ENST00000471698.1
ENST00000189444.6 |
NFKB2
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| chr7_+_143078652 | 2.55 |
ENST00000354434.4
ENST00000449423.2 |
ZYX
|
zyxin |
| chr19_-_11688260 | 2.51 |
ENST00000590832.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr6_+_29691198 | 2.51 |
ENST00000440587.2
ENST00000434407.2 |
HLA-F
|
major histocompatibility complex, class I, F |
| chr19_+_35940486 | 2.51 |
ENST00000246549.2
|
FFAR2
|
free fatty acid receptor 2 |
| chr10_+_30723533 | 2.50 |
ENST00000413724.1
|
MAP3K8
|
mitogen-activated protein kinase kinase kinase 8 |
| chr19_-_11688447 | 2.44 |
ENST00000590420.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr1_-_202130702 | 2.43 |
ENST00000309017.3
ENST00000477554.1 ENST00000492451.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr5_+_118604385 | 2.41 |
ENST00000274456.6
|
TNFAIP8
|
tumor necrosis factor, alpha-induced protein 8 |
| chr7_+_143078379 | 2.40 |
ENST00000449630.1
ENST00000457235.1 |
ZYX
|
zyxin |
| chr14_+_22573582 | 2.35 |
ENST00000390453.1
|
TRAV24
|
T cell receptor alpha variable 24 |
| chr6_+_144471643 | 2.35 |
ENST00000367568.4
|
STX11
|
syntaxin 11 |
| chr7_-_27169801 | 2.32 |
ENST00000511914.1
|
HOXA4
|
homeobox A4 |
| chr14_+_61789382 | 2.28 |
ENST00000555082.1
|
PRKCH
|
protein kinase C, eta |
| chr1_+_201979743 | 2.26 |
ENST00000446188.1
|
ELF3
|
E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| chr9_-_136344197 | 2.26 |
ENST00000414172.1
ENST00000371897.4 |
SLC2A6
|
solute carrier family 2 (facilitated glucose transporter), member 6 |
| chr3_-_111852128 | 2.26 |
ENST00000308910.4
|
GCSAM
|
germinal center-associated, signaling and motility |
| chr1_-_202129105 | 2.25 |
ENST00000367279.4
|
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr1_-_209825674 | 2.23 |
ENST00000367030.3
ENST00000356082.4 |
LAMB3
|
laminin, beta 3 |
| chr19_+_10381769 | 2.20 |
ENST00000423829.2
ENST00000588645.1 |
ICAM1
|
intercellular adhesion molecule 1 |
| chr12_-_57504069 | 2.13 |
ENST00000543873.2
ENST00000554663.1 ENST00000557635.1 |
STAT6
|
signal transducer and activator of transcription 6, interleukin-4 induced |
| chr11_-_58345569 | 2.12 |
ENST00000528954.1
ENST00000528489.1 |
LPXN
|
leupaxin |
| chr11_-_75062730 | 2.11 |
ENST00000420843.2
ENST00000360025.3 |
ARRB1
|
arrestin, beta 1 |
| chr18_+_3252265 | 2.10 |
ENST00000580887.1
ENST00000536605.1 |
MYL12A
|
myosin, light chain 12A, regulatory, non-sarcomeric |
| chr17_+_40440094 | 2.08 |
ENST00000546010.2
|
STAT5A
|
signal transducer and activator of transcription 5A |
| chr20_-_45530365 | 2.08 |
ENST00000414085.1
|
RP11-323C15.2
|
RP11-323C15.2 |
| chr16_+_3096638 | 2.07 |
ENST00000336577.4
|
MMP25
|
matrix metallopeptidase 25 |
| chr19_-_11688500 | 2.07 |
ENST00000433365.2
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr3_+_111578027 | 2.06 |
ENST00000431670.2
ENST00000412622.1 |
PHLDB2
|
pleckstrin homology-like domain, family B, member 2 |
| chr13_+_108922228 | 2.03 |
ENST00000542136.1
|
TNFSF13B
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr12_-_22487588 | 2.01 |
ENST00000381424.3
|
ST8SIA1
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
| chr10_-_6104253 | 1.99 |
ENST00000256876.6
ENST00000379954.1 ENST00000379959.3 |
IL2RA
|
interleukin 2 receptor, alpha |
| chr19_+_41281060 | 1.99 |
ENST00000594436.1
ENST00000597784.1 |
MIA
|
melanoma inhibitory activity |
| chr12_-_55375622 | 1.98 |
ENST00000316577.8
|
TESPA1
|
thymocyte expressed, positive selection associated 1 |
| chr1_-_202129704 | 1.97 |
ENST00000476061.1
ENST00000544762.1 ENST00000467283.1 ENST00000464870.1 ENST00000435759.2 ENST00000486116.1 ENST00000543735.1 ENST00000308986.5 ENST00000477625.1 |
PTPN7
|
protein tyrosine phosphatase, non-receptor type 7 |
| chr1_-_236030216 | 1.96 |
ENST00000389794.3
ENST00000389793.2 |
LYST
|
lysosomal trafficking regulator |
| chr4_+_74702214 | 1.95 |
ENST00000226317.5
ENST00000515050.1 |
CXCL6
|
chemokine (C-X-C motif) ligand 6 |
| chr9_+_127054254 | 1.91 |
ENST00000422297.1
|
NEK6
|
NIMA-related kinase 6 |
| chr2_-_43453734 | 1.89 |
ENST00000282388.3
|
ZFP36L2
|
ZFP36 ring finger protein-like 2 |
| chr2_-_191885686 | 1.88 |
ENST00000432058.1
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa |
| chr1_-_155959853 | 1.88 |
ENST00000462460.2
ENST00000368316.1 |
ARHGEF2
|
Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| chr2_+_201987200 | 1.87 |
ENST00000425030.1
|
CFLAR
|
CASP8 and FADD-like apoptosis regulator |
| chr17_+_38474489 | 1.85 |
ENST00000394089.2
ENST00000425707.3 |
RARA
|
retinoic acid receptor, alpha |
| chr1_+_66820058 | 1.84 |
ENST00000480109.2
|
PDE4B
|
phosphodiesterase 4B, cAMP-specific |
| chr12_+_52430894 | 1.82 |
ENST00000546842.1
|
NR4A1
|
nuclear receptor subfamily 4, group A, member 1 |
| chr3_-_158390282 | 1.81 |
ENST00000264265.3
|
LXN
|
latexin |
| chr2_+_61108771 | 1.80 |
ENST00000394479.3
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog |
| chr4_-_185395672 | 1.79 |
ENST00000393593.3
|
IRF2
|
interferon regulatory factor 2 |
| chr6_+_29910301 | 1.76 |
ENST00000376809.5
ENST00000376802.2 |
HLA-A
|
major histocompatibility complex, class I, A |
| chr11_+_118754475 | 1.76 |
ENST00000292174.4
|
CXCR5
|
chemokine (C-X-C motif) receptor 5 |
| chr7_+_143771275 | 1.76 |
ENST00000408898.2
|
OR2A25
|
olfactory receptor, family 2, subfamily A, member 25 |
| chr1_+_111770232 | 1.73 |
ENST00000369744.2
|
CHI3L2
|
chitinase 3-like 2 |
| chr1_+_186649754 | 1.73 |
ENST00000608917.1
|
RP5-973M2.2
|
RP5-973M2.2 |
| chr1_+_111770278 | 1.72 |
ENST00000369748.4
|
CHI3L2
|
chitinase 3-like 2 |
| chr3_+_111578131 | 1.72 |
ENST00000498699.1
|
PHLDB2
|
pleckstrin homology-like domain, family B, member 2 |
| chr3_+_157154578 | 1.71 |
ENST00000295927.3
|
PTX3
|
pentraxin 3, long |
| chr20_-_62203808 | 1.69 |
ENST00000467148.1
|
HELZ2
|
helicase with zinc finger 2, transcriptional coactivator |
| chr11_-_75062829 | 1.68 |
ENST00000393505.4
|
ARRB1
|
arrestin, beta 1 |
| chr1_+_26869597 | 1.67 |
ENST00000530003.1
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| chr6_-_30712313 | 1.67 |
ENST00000376377.2
ENST00000259874.5 |
IER3
|
immediate early response 3 |
| chr22_-_19512893 | 1.67 |
ENST00000403084.1
ENST00000413119.2 |
CLDN5
|
claudin 5 |
| chr6_-_74231303 | 1.66 |
ENST00000309268.6
|
EEF1A1
|
eukaryotic translation elongation factor 1 alpha 1 |
| chr4_+_103422499 | 1.66 |
ENST00000511926.1
ENST00000507079.1 |
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| chr17_-_4852332 | 1.64 |
ENST00000572383.1
|
PFN1
|
profilin 1 |
| chr11_+_72525353 | 1.64 |
ENST00000321297.5
ENST00000534905.1 ENST00000540567.1 |
ATG16L2
|
autophagy related 16-like 2 (S. cerevisiae) |
| chr21_+_34775698 | 1.62 |
ENST00000381995.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr12_-_127256858 | 1.61 |
ENST00000542248.1
ENST00000540684.1 |
LINC00944
|
long intergenic non-protein coding RNA 944 |
| chr1_+_100818156 | 1.59 |
ENST00000336454.3
|
CDC14A
|
cell division cycle 14A |
| chr8_-_101724989 | 1.59 |
ENST00000517403.1
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1 |
| chr1_-_153935983 | 1.58 |
ENST00000537590.1
ENST00000356205.4 |
SLC39A1
|
solute carrier family 39 (zinc transporter), member 1 |
| chr12_-_127256772 | 1.58 |
ENST00000536517.1
|
LINC00944
|
long intergenic non-protein coding RNA 944 |
| chr21_+_34775772 | 1.58 |
ENST00000405436.1
|
IFNGR2
|
interferon gamma receptor 2 (interferon gamma transducer 1) |
| chr19_+_42364460 | 1.57 |
ENST00000593863.1
|
RPS19
|
ribosomal protein S19 |
| chr13_+_108921977 | 1.54 |
ENST00000430559.1
ENST00000375887.4 |
TNFSF13B
|
tumor necrosis factor (ligand) superfamily, member 13b |
| chr7_+_120629653 | 1.52 |
ENST00000450913.2
ENST00000340646.5 |
CPED1
|
cadherin-like and PC-esterase domain containing 1 |
| chr4_-_40631859 | 1.50 |
ENST00000295971.7
ENST00000319592.4 |
RBM47
|
RNA binding motif protein 47 |
| chr6_-_74230741 | 1.48 |
ENST00000316292.9
|
EEF1A1
|
eukaryotic translation elongation factor 1 alpha 1 |
| chr14_+_22984601 | 1.47 |
ENST00000390509.1
|
TRAJ28
|
T cell receptor alpha joining 28 |
| chr19_+_51728316 | 1.47 |
ENST00000436584.2
ENST00000421133.2 ENST00000391796.3 ENST00000262262.4 |
CD33
|
CD33 molecule |
| chr4_-_174256276 | 1.47 |
ENST00000296503.5
|
HMGB2
|
high mobility group box 2 |
| chr1_-_153935938 | 1.46 |
ENST00000368621.1
ENST00000368623.3 |
SLC39A1
|
solute carrier family 39 (zinc transporter), member 1 |
| chr12_+_11802753 | 1.45 |
ENST00000396373.4
|
ETV6
|
ets variant 6 |
| chr12_-_57023995 | 1.45 |
ENST00000549884.1
ENST00000546695.1 |
BAZ2A
|
bromodomain adjacent to zinc finger domain, 2A |
| chr19_+_42363917 | 1.44 |
ENST00000598742.1
|
RPS19
|
ribosomal protein S19 |
| chr5_-_158526693 | 1.44 |
ENST00000380654.4
|
EBF1
|
early B-cell factor 1 |
| chr5_-_158526756 | 1.44 |
ENST00000313708.6
ENST00000517373.1 |
EBF1
|
early B-cell factor 1 |
| chr12_+_7055631 | 1.43 |
ENST00000543115.1
ENST00000399448.1 |
PTPN6
|
protein tyrosine phosphatase, non-receptor type 6 |
| chr1_-_41950342 | 1.42 |
ENST00000372587.4
|
EDN2
|
endothelin 2 |
| chr6_-_29527702 | 1.42 |
ENST00000377050.4
|
UBD
|
ubiquitin D |
| chr5_+_118604439 | 1.39 |
ENST00000388882.5
|
TNFAIP8
|
tumor necrosis factor, alpha-induced protein 8 |
| chr14_+_22985251 | 1.39 |
ENST00000390510.1
|
TRAJ27
|
T cell receptor alpha joining 27 |
| chr5_-_141338377 | 1.38 |
ENST00000510041.1
|
PCDH12
|
protocadherin 12 |
| chr12_+_65672702 | 1.36 |
ENST00000538045.1
ENST00000535239.1 |
MSRB3
|
methionine sulfoxide reductase B3 |
| chr1_+_156123318 | 1.36 |
ENST00000368285.3
|
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| chr3_+_52280173 | 1.35 |
ENST00000296487.4
|
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr2_+_97202480 | 1.35 |
ENST00000357485.3
|
ARID5A
|
AT rich interactive domain 5A (MRF1-like) |
| chr19_+_42364313 | 1.34 |
ENST00000601492.1
ENST00000600467.1 ENST00000221975.2 |
RPS19
|
ribosomal protein S19 |
| chr19_-_11688951 | 1.33 |
ENST00000589792.1
|
ACP5
|
acid phosphatase 5, tartrate resistant |
| chr7_-_100881109 | 1.32 |
ENST00000308344.5
|
CLDN15
|
claudin 15 |
| chr1_+_247579451 | 1.32 |
ENST00000391828.3
ENST00000366497.2 |
NLRP3
|
NLR family, pyrin domain containing 3 |
| chr1_+_156123359 | 1.32 |
ENST00000368284.1
ENST00000368286.2 ENST00000438830.1 |
SEMA4A
|
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| chr5_-_150460539 | 1.31 |
ENST00000520931.1
ENST00000520695.1 ENST00000521591.1 ENST00000518977.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr16_+_50775948 | 1.30 |
ENST00000569681.1
ENST00000569418.1 ENST00000540145.1 |
CYLD
|
cylindromatosis (turban tumor syndrome) |
| chr1_+_100818009 | 1.29 |
ENST00000370125.2
ENST00000361544.6 ENST00000370124.3 |
CDC14A
|
cell division cycle 14A |
| chr1_-_161168834 | 1.29 |
ENST00000367995.3
ENST00000367996.5 |
ADAMTS4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| chr18_-_12884259 | 1.29 |
ENST00000353319.4
ENST00000327283.3 |
PTPN2
|
protein tyrosine phosphatase, non-receptor type 2 |
| chr15_+_57884117 | 1.28 |
ENST00000267853.5
|
MYZAP
|
myocardial zonula adherens protein |
| chr2_+_233925064 | 1.28 |
ENST00000359570.5
ENST00000538935.1 |
INPP5D
|
inositol polyphosphate-5-phosphatase, 145kDa |
| chr3_+_184033551 | 1.28 |
ENST00000456033.1
|
EIF4G1
|
eukaryotic translation initiation factor 4 gamma, 1 |
| chr3_+_52280220 | 1.26 |
ENST00000409502.3
ENST00000323588.4 |
PPM1M
|
protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| chr14_+_103243813 | 1.26 |
ENST00000560371.1
ENST00000347662.4 ENST00000392745.2 ENST00000539721.1 ENST00000560463.1 |
TRAF3
|
TNF receptor-associated factor 3 |
| chr11_-_96076334 | 1.26 |
ENST00000524717.1
|
MAML2
|
mastermind-like 2 (Drosophila) |
| chr5_-_150466692 | 1.24 |
ENST00000315050.7
ENST00000523338.1 ENST00000522100.1 |
TNIP1
|
TNFAIP3 interacting protein 1 |
| chr7_+_120969045 | 1.24 |
ENST00000222462.2
|
WNT16
|
wingless-type MMTV integration site family, member 16 |
| chr1_+_111770294 | 1.23 |
ENST00000474304.2
|
CHI3L2
|
chitinase 3-like 2 |
| chrX_-_131353461 | 1.23 |
ENST00000370874.1
|
RAP2C
|
RAP2C, member of RAS oncogene family |
| chr8_+_38758737 | 1.23 |
ENST00000521746.1
ENST00000420274.1 |
PLEKHA2
|
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| chr2_-_109605663 | 1.23 |
ENST00000409271.1
ENST00000258443.2 ENST00000376651.1 |
EDAR
|
ectodysplasin A receptor |
| chr2_+_161993465 | 1.22 |
ENST00000457476.1
|
TANK
|
TRAF family member-associated NFKB activator |
| chr1_+_145477060 | 1.21 |
ENST00000369308.3
|
LIX1L
|
Lix1 homolog (mouse)-like |
| chr17_-_7590745 | 1.19 |
ENST00000514944.1
ENST00000503591.1 ENST00000455263.2 ENST00000420246.2 ENST00000445888.2 ENST00000509690.1 ENST00000604348.1 ENST00000269305.4 |
TP53
|
tumor protein p53 |
| chr18_+_3450161 | 1.17 |
ENST00000551402.1
ENST00000577543.1 |
TGIF1
|
TGFB-induced factor homeobox 1 |
| chr2_+_97203082 | 1.16 |
ENST00000454558.2
|
ARID5A
|
AT rich interactive domain 5A (MRF1-like) |
| chr11_+_57508825 | 1.16 |
ENST00000534355.1
|
C11orf31
|
chromosome 11 open reading frame 31 |
| chr2_+_202047843 | 1.14 |
ENST00000272879.5
ENST00000374650.3 ENST00000346817.5 ENST00000313728.7 ENST00000448480.1 |
CASP10
|
caspase 10, apoptosis-related cysteine peptidase |
| chr1_-_38100491 | 1.13 |
ENST00000356545.2
|
RSPO1
|
R-spondin 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of RELA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.7 | 17.1 | GO:0072573 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
| 2.6 | 10.3 | GO:0002268 | follicular dendritic cell differentiation(GO:0002268) |
| 2.1 | 6.4 | GO:0002731 | negative regulation of dendritic cell cytokine production(GO:0002731) |
| 1.8 | 5.5 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 1.4 | 1.4 | GO:0060585 | regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) |
| 1.3 | 10.4 | GO:0038110 | interleukin-2-mediated signaling pathway(GO:0038110) |
| 1.3 | 16.4 | GO:0043950 | positive regulation of cAMP-mediated signaling(GO:0043950) |
| 1.2 | 7.4 | GO:2000110 | negative regulation of macrophage apoptotic process(GO:2000110) |
| 1.2 | 3.6 | GO:1990654 | sebum secreting cell proliferation(GO:1990654) |
| 1.2 | 3.5 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 1.1 | 3.4 | GO:0002522 | leukocyte migration involved in immune response(GO:0002522) |
| 1.1 | 3.3 | GO:0070427 | nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) |
| 1.1 | 4.3 | GO:0060265 | positive regulation of respiratory burst involved in inflammatory response(GO:0060265) |
| 1.1 | 7.6 | GO:0045084 | positive regulation of interleukin-12 biosynthetic process(GO:0045084) |
| 1.1 | 3.2 | GO:0072616 | interleukin-18 secretion(GO:0072616) |
| 1.0 | 8.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 1.0 | 29.8 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 1.0 | 3.0 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 1.0 | 2.9 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) |
| 0.9 | 2.8 | GO:0045362 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.9 | 10.9 | GO:0070424 | regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424) |
| 0.9 | 2.6 | GO:0045083 | negative regulation of interleukin-12 biosynthetic process(GO:0045083) |
| 0.8 | 2.5 | GO:0002232 | leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752) |
| 0.8 | 4.2 | GO:0038156 | interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156) |
| 0.8 | 3.3 | GO:0002384 | hepatic immune response(GO:0002384) response to prolactin(GO:1990637) |
| 0.8 | 3.9 | GO:0052027 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.7 | 3.6 | GO:0031296 | positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296) |
| 0.7 | 4.9 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.7 | 6.9 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.7 | 2.7 | GO:0002925 | positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.7 | 2.0 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.5 | 2.7 | GO:1903899 | positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.5 | 2.1 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.5 | 4.0 | GO:2000402 | negative regulation of lymphocyte migration(GO:2000402) |
| 0.5 | 2.4 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 0.5 | 4.8 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 0.5 | 1.9 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.4 | 6.7 | GO:0048733 | sebaceous gland development(GO:0048733) |
| 0.4 | 2.2 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.4 | 1.7 | GO:0001878 | response to yeast(GO:0001878) |
| 0.4 | 5.5 | GO:0043435 | response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376) |
| 0.4 | 12.2 | GO:0043011 | myeloid dendritic cell differentiation(GO:0043011) |
| 0.4 | 5.5 | GO:1901409 | positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409) |
| 0.4 | 3.4 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.4 | 3.8 | GO:0042699 | follicle-stimulating hormone signaling pathway(GO:0042699) |
| 0.4 | 2.6 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.4 | 1.8 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.4 | 2.6 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.4 | 2.9 | GO:0071802 | negative regulation of podosome assembly(GO:0071802) |
| 0.4 | 1.8 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.4 | 3.5 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
| 0.3 | 1.7 | GO:0097403 | cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545) |
| 0.3 | 6.0 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.3 | 1.0 | GO:0090427 | activation of meiosis(GO:0090427) |
| 0.3 | 3.3 | GO:0034351 | regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) |
| 0.3 | 0.3 | GO:2000152 | regulation of ubiquitin-specific protease activity(GO:2000152) |
| 0.3 | 2.9 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.3 | 2.0 | GO:0010387 | COP9 signalosome assembly(GO:0010387) |
| 0.3 | 1.7 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 0.3 | 1.6 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.3 | 0.8 | GO:0089700 | protein kinase D signaling(GO:0089700) |
| 0.3 | 1.1 | GO:0000103 | sulfate assimilation(GO:0000103) |
| 0.3 | 4.7 | GO:0006030 | chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) |
| 0.2 | 3.8 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.2 | 1.3 | GO:0032621 | interleukin-18 production(GO:0032621) |
| 0.2 | 0.6 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.2 | 1.3 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.2 | 4.1 | GO:0051601 | exocyst localization(GO:0051601) |
| 0.2 | 0.8 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.2 | 1.2 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.2 | 28.2 | GO:0031295 | lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295) |
| 0.2 | 1.9 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.2 | 0.6 | GO:0051685 | maintenance of ER location(GO:0051685) |
| 0.2 | 2.4 | GO:0030091 | protein repair(GO:0030091) |
| 0.2 | 1.5 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.2 | 1.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.2 | 0.9 | GO:0034141 | positive regulation of toll-like receptor 3 signaling pathway(GO:0034141) |
| 0.2 | 7.0 | GO:0003094 | glomerular filtration(GO:0003094) |
| 0.2 | 4.4 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.2 | 0.5 | GO:0032203 | telomere formation via telomerase(GO:0032203) |
| 0.2 | 2.1 | GO:0060022 | hard palate development(GO:0060022) |
| 0.2 | 1.9 | GO:1903944 | negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.1 | 1.0 | GO:0045627 | positive regulation of T-helper 1 cell differentiation(GO:0045627) |
| 0.1 | 0.9 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.1 | 0.9 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183) |
| 0.1 | 3.1 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.1 | 1.7 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.1 | 2.6 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 1.6 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.1 | 2.2 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 2.7 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.1 | 1.6 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.1 | 0.2 | GO:0019933 | cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935) |
| 0.1 | 4.1 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 1.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.1 | 1.7 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.1 | 2.0 | GO:0001780 | neutrophil homeostasis(GO:0001780) |
| 0.1 | 1.0 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 1.6 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.1 | 1.0 | GO:0055118 | negative regulation of cardiac muscle contraction(GO:0055118) |
| 0.1 | 0.3 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619) |
| 0.1 | 2.3 | GO:0099500 | synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500) |
| 0.1 | 0.7 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.1 | 0.5 | GO:0045359 | interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.1 | 0.4 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
| 0.1 | 1.9 | GO:0048535 | lymph node development(GO:0048535) |
| 0.1 | 7.9 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.1 | 2.6 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.6 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.1 | 1.8 | GO:0050965 | detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965) |
| 0.1 | 1.1 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.1 | 0.5 | GO:2000510 | positive regulation of dendritic cell chemotaxis(GO:2000510) |
| 0.1 | 1.2 | GO:0060605 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.1 | 0.4 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.1 | 1.1 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 1.1 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.1 | 2.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 2.7 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 2.2 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
| 0.1 | 0.3 | GO:0033590 | response to cobalamin(GO:0033590) |
| 0.1 | 0.9 | GO:0098734 | macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 4.7 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 6.4 | GO:0042100 | B cell proliferation(GO:0042100) |
| 0.1 | 0.7 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.1 | 3.1 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.1 | 0.4 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
| 0.1 | 0.8 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.1 | 0.6 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
| 0.1 | 1.9 | GO:0071498 | cellular response to fluid shear stress(GO:0071498) |
| 0.1 | 0.3 | GO:0036343 | psychomotor behavior(GO:0036343) |
| 0.1 | 2.3 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.1 | 0.7 | GO:0045807 | positive regulation of endocytosis(GO:0045807) |
| 0.1 | 0.3 | GO:1902534 | single-organism membrane invagination(GO:1902534) |
| 0.0 | 4.7 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 0.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.0 | 0.3 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.0 | 1.0 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.0 | 0.4 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.0 | 4.0 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 2.5 | GO:0071391 | cellular response to estrogen stimulus(GO:0071391) |
| 0.0 | 0.7 | GO:0070365 | hepatocyte differentiation(GO:0070365) |
| 0.0 | 1.0 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 2.0 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.0 | 3.7 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) |
| 0.0 | 0.6 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.0 | 1.2 | GO:0097352 | autophagosome maturation(GO:0097352) |
| 0.0 | 2.8 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.0 | 0.4 | GO:0038171 | cannabinoid signaling pathway(GO:0038171) |
| 0.0 | 0.2 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.0 | 0.2 | GO:0097461 | ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.0 | 4.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 1.1 | GO:0045670 | regulation of osteoclast differentiation(GO:0045670) |
| 0.0 | 0.6 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 0.1 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.0 | 0.2 | GO:0097688 | AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) |
| 0.0 | 0.1 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.0 | 1.4 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 0.6 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 3.8 | GO:0043149 | contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149) |
| 0.0 | 0.8 | GO:0034142 | toll-like receptor 4 signaling pathway(GO:0034142) |
| 0.0 | 0.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.9 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.0 | 0.7 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.0 | 1.4 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 1.4 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 0.9 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.0 | 3.1 | GO:1905037 | autophagosome organization(GO:1905037) |
| 0.0 | 0.4 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 0.0 | 5.3 | GO:0097191 | extrinsic apoptotic signaling pathway(GO:0097191) |
| 0.0 | 0.3 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.0 | 0.4 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.0 | 1.2 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 0.7 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.4 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 0.4 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.0 | 0.2 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 1.0 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.0 | 2.5 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 0.5 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.1 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.0 | 0.1 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 1.4 | GO:0006306 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.0 | 0.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.0 | 0.4 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.9 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 2.0 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
| 0.0 | 1.0 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.4 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
| 0.0 | 0.4 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 10.3 | GO:0033257 | Bcl3/NF-kappaB2 complex(GO:0033257) |
| 2.3 | 7.0 | GO:0071749 | IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751) |
| 1.4 | 4.2 | GO:0030526 | granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526) |
| 1.3 | 12.7 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 1.3 | 8.8 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.7 | 15.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.6 | 3.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.6 | 6.9 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.5 | 6.0 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.3 | 2.6 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.3 | 0.9 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.3 | 1.1 | GO:0043291 | RAVE complex(GO:0043291) |
| 0.3 | 4.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.2 | 1.0 | GO:0031251 | PAN complex(GO:0031251) |
| 0.2 | 2.7 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 3.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.2 | 1.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.2 | 0.7 | GO:0005889 | hydrogen:potassium-exchanging ATPase complex(GO:0005889) |
| 0.2 | 4.3 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.2 | 0.9 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.1 | 4.5 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 1.4 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.1 | 4.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 3.1 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 1.6 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 38.9 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 0.3 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.1 | 5.7 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 1.3 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.1 | 6.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 0.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 5.5 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.1 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 6.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 0.7 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.1 | 2.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.1 | 6.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 4.8 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.4 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 1.4 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 1.6 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 3.5 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.1 | 1.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 1.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.3 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.4 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.0 | 4.9 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.6 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 2.3 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.7 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 5.3 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.5 | GO:0031906 | late endosome lumen(GO:0031906) |
| 0.0 | 1.0 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 6.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 10.5 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 1.0 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 32.5 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 1.1 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.0 | 7.1 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 3.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 1.7 | GO:0097610 | cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610) |
| 0.0 | 1.2 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 4.9 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.0 | 2.7 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.3 | GO:0042641 | actomyosin(GO:0042641) |
| 0.0 | 2.1 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 1.4 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 6.0 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.6 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 2.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.4 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.5 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 1.3 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 0.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 0.4 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 25.7 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 0.2 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
| 0.0 | 0.1 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.7 | GO:1990391 | DNA repair complex(GO:1990391) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.3 | 16.4 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 1.8 | 19.6 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 1.7 | 8.4 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 1.3 | 3.8 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
| 1.1 | 5.5 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473) |
| 1.1 | 20.6 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.9 | 2.8 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.9 | 1.8 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.9 | 4.4 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.8 | 4.2 | GO:0004912 | interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914) |
| 0.7 | 5.1 | GO:0046979 | TAP2 binding(GO:0046979) |
| 0.7 | 4.1 | GO:0004906 | interferon-gamma receptor activity(GO:0004906) |
| 0.6 | 11.0 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.6 | 4.1 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.5 | 3.3 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.4 | 23.8 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.4 | 8.4 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.4 | 3.4 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.4 | 16.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.4 | 1.1 | GO:0004781 | adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781) |
| 0.3 | 2.4 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.3 | 3.2 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.3 | 5.1 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.3 | 3.4 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.3 | 17.0 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.3 | 2.6 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.3 | 1.5 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.3 | 1.4 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.3 | 3.1 | GO:0035005 | lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.3 | 2.2 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.3 | 2.7 | GO:0019863 | IgE binding(GO:0019863) |
| 0.3 | 4.7 | GO:0004568 | chitinase activity(GO:0004568) |
| 0.3 | 1.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.2 | 4.6 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.2 | 3.0 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 1.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.2 | 3.0 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.2 | 4.4 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.2 | 4.7 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.2 | 1.8 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 2.0 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.2 | 1.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.2 | 8.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.1 | 0.8 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.5 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.1 | 3.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 1.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.5 | GO:0004583 | dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583) |
| 0.1 | 4.3 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 1.8 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) |
| 0.1 | 0.3 | GO:0046969 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.1 | 5.5 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.1 | 2.3 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.1 | 0.3 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.1 | 1.8 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.1 | 0.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 1.4 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 1.2 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 0.1 | 0.9 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 2.9 | GO:0070742 | C2H2 zinc finger domain binding(GO:0070742) |
| 0.1 | 3.1 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.7 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 2.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.3 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 3.3 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 5.5 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.6 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.1 | 0.4 | GO:0004949 | cannabinoid receptor activity(GO:0004949) |
| 0.1 | 0.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 1.4 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 0.6 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.1 | 1.7 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.1 | 1.1 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 3.9 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.1 | 0.9 | GO:0098599 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 2.9 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 2.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 2.7 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 1.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.1 | 0.6 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.4 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.1 | 0.7 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 2.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 5.5 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.1 | 1.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 1.1 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 5.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 1.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 8.1 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 1.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.2 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.0 | 2.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.3 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 0.0 | 2.6 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.0 | 1.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.6 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.4 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 2.0 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 2.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 21.8 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 0.2 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.0 | 1.6 | GO:0035326 | enhancer binding(GO:0035326) |
| 0.0 | 11.5 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
| 0.0 | 1.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 1.4 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.0 | 1.0 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.0 | 0.9 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.1 | GO:0050115 | myosin-light-chain-phosphatase activity(GO:0050115) |
| 0.0 | 1.2 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 5.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 1.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.0 | 0.9 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 1.1 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
| 0.0 | 2.4 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 3.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.2 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.0 | 2.9 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 4.5 | GO:0019887 | protein kinase regulator activity(GO:0019887) |
| 0.0 | 2.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.9 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.7 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 2.3 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.4 | GO:0015002 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 23.8 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.7 | 46.9 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.5 | 8.5 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.3 | 22.4 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.3 | 28.5 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.2 | 4.7 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.2 | 4.2 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.2 | 5.5 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 16.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 5.2 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.2 | 7.6 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.2 | 6.6 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 4.2 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 7.4 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.1 | 3.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 7.8 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 3.0 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 2.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 4.9 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 2.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 3.7 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 1.7 | ST ADRENERGIC | Adrenergic Pathway |
| 0.1 | 1.3 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 0.7 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.1 | 3.1 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 8.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 2.3 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 2.3 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 1.5 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.1 | 0.9 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.1 | 1.7 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.9 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.0 | 16.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 9.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.9 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.2 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.6 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 1.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 0.4 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.0 | 0.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.3 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.7 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.7 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.2 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 2.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.7 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.6 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.3 | PID INSULIN PATHWAY | Insulin Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 6.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.6 | 44.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.5 | 35.1 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.4 | 9.6 | REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX | Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex |
| 0.4 | 16.9 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.4 | 12.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.3 | 8.7 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.3 | 12.5 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.3 | 8.0 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.3 | 3.2 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 9.0 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.2 | 8.8 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.2 | 2.6 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 7.0 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 11.3 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 4.3 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 5.0 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 3.7 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.1 | 5.5 | REACTOME PIP3 ACTIVATES AKT SIGNALING | Genes involved in PIP3 activates AKT signaling |
| 0.1 | 6.0 | REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | Genes involved in Thrombin signalling through proteinase activated receptors (PARs) |
| 0.1 | 0.5 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.1 | 1.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.1 | 2.3 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 1.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 1.5 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 1.7 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 8.7 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.6 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 2.7 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 2.0 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.1 | 2.6 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.1 | 1.8 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 1.3 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 1.1 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.1 | 7.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 5.9 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.1 | 1.3 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 1.1 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.1 | 2.2 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 4.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 2.3 | REACTOME G ALPHA Z SIGNALLING EVENTS | Genes involved in G alpha (z) signalling events |
| 0.0 | 5.5 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 2.1 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.4 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 1.1 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 3.1 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 1.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 2.4 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.2 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 1.0 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.4 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 3.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 1.7 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.0 | 0.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME PI METABOLISM | Genes involved in PI Metabolism |
| 0.0 | 1.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.7 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.5 | REACTOME ACTIVATION OF NF KAPPAB IN B CELLS | Genes involved in Activation of NF-kappaB in B Cells |
| 0.0 | 0.5 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 1.2 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.4 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 2.2 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.7 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.5 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |