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Illumina Body Map 2

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Results for RELB

Z-value: 1.02

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Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
RELB
ENSG00000104856.9 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg19_v2_chr19_+_45504688_455047820.192.9e-01Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_159174701 3.00 ENST00000435307.1
DARC
Duffy blood group, atypical chemokine receptor
chr15_+_33010175 2.79 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr14_-_106967788 2.75 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr2_+_89952792 2.43 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr2_-_89476644 2.35 ENST00000484817.1
IGKV2-24
immunoglobulin kappa variable 2-24
chr22_+_23222886 2.34 ENST00000390319.2
IGLV3-1
immunoglobulin lambda variable 3-1
chr22_-_19512893 2.16 ENST00000403084.1
ENST00000413119.2
CLDN5
claudin 5
chr2_-_89619904 2.13 ENST00000498574.1
IGKV1-39
immunoglobulin kappa variable 1-39 (gene/pseudogene)
chr13_-_78492927 2.11 ENST00000334286.5
EDNRB
endothelin receptor type B
chr19_+_42381173 2.10 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr13_-_78492955 2.10 ENST00000446573.1
EDNRB
endothelin receptor type B
chr19_+_42381337 2.00 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr2_-_89310012 1.96 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr11_+_18287721 1.92 ENST00000356524.4
SAA1
serum amyloid A1
chr11_+_18287801 1.88 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr2_-_89247338 1.82 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr22_+_23134974 1.71 ENST00000390314.2
IGLV2-11
immunoglobulin lambda variable 2-11
chr12_-_8815215 1.70 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr12_-_8815299 1.68 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr6_-_29527702 1.64 ENST00000377050.4
UBD
ubiquitin D
chr22_+_22786288 1.64 ENST00000390301.2
IGLV1-36
immunoglobulin lambda variable 1-36
chr2_-_89340242 1.56 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr2_-_89568263 1.54 ENST00000473726.1
IGKV1-33
immunoglobulin kappa variable 1-33
chr19_-_6591113 1.50 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr7_+_22766766 1.48 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_95392635 1.42 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr1_+_161228517 1.39 ENST00000504449.1
PCP4L1
Purkinje cell protein 4 like 1
chr1_+_11249398 1.33 ENST00000376819.3
ANGPTL7
angiopoietin-like 7
chr17_-_74547256 1.33 ENST00000589145.1
CYGB
cytoglobin
chr1_-_186649543 1.32 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_114163945 1.31 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr14_-_106471723 1.30 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr19_+_18492973 1.25 ENST00000595973.2
GDF15
growth differentiation factor 15
chr7_+_89783689 1.21 ENST00000297205.2
STEAP1
six transmembrane epithelial antigen of the prostate 1
chr7_+_33945106 1.16 ENST00000426693.1
BMPER
BMP binding endothelial regulator
chr12_-_8815404 1.16 ENST00000359478.2
ENST00000396549.2
MFAP5
microfibrillar associated protein 5
chr3_-_168864315 1.14 ENST00000475754.1
ENST00000484519.1
MECOM
MDS1 and EVI1 complex locus
chr17_+_12569306 1.13 ENST00000425538.1
MYOCD
myocardin
chr1_+_201979645 1.13 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_-_74864386 1.07 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr13_+_53602894 1.06 ENST00000219022.2
OLFM4
olfactomedin 4
chr10_-_118031778 1.04 ENST00000369236.1
GFRA1
GDNF family receptor alpha 1
chrX_-_133119895 1.03 ENST00000370818.3
GPC3
glypican 3
chr12_-_8815477 1.02 ENST00000433590.2
MFAP5
microfibrillar associated protein 5
chr4_-_74964904 1.02 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr5_-_146833485 1.02 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr5_-_146833222 0.97 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chrX_-_65253506 0.97 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr14_-_25045446 0.97 ENST00000216336.2
CTSG
cathepsin G
chr2_-_36779411 0.95 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr12_+_54422142 0.91 ENST00000243108.4
HOXC6
homeobox C6
chr1_-_204436344 0.91 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr7_-_27239703 0.91 ENST00000222753.4
HOXA13
homeobox A13
chr10_+_89419370 0.88 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_+_30722866 0.86 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr18_-_70535177 0.86 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr2_-_27718052 0.85 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chrX_+_15518923 0.85 ENST00000348343.6
BMX
BMX non-receptor tyrosine kinase
chr2_-_56150184 0.84 ENST00000394554.1
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr1_+_37940153 0.84 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr18_+_21529811 0.83 ENST00000588004.1
LAMA3
laminin, alpha 3
chr10_-_7708918 0.81 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr3_+_148415571 0.81 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chr22_-_37640277 0.78 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr1_+_117297007 0.77 ENST00000369478.3
ENST00000369477.1
CD2
CD2 molecule
chr12_-_53074182 0.77 ENST00000252244.3
KRT1
keratin 1
chr11_-_5271122 0.77 ENST00000330597.3
HBG1
hemoglobin, gamma A
chr14_+_52734401 0.76 ENST00000306051.2
ENST00000553372.1
PTGDR
prostaglandin D2 receptor (DP)
chr8_-_57472154 0.75 ENST00000499425.1
ENST00000523664.1
ENST00000518943.1
ENST00000524338.1
LINC00968
long intergenic non-protein coding RNA 968
chr3_-_156878540 0.75 ENST00000461804.1
CCNL1
cyclin L1
chr7_-_22539771 0.75 ENST00000406890.2
ENST00000424363.1
STEAP1B
STEAP family member 1B
chr22_-_28490123 0.74 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr9_+_35792151 0.73 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr19_-_17958771 0.72 ENST00000534444.1
JAK3
Janus kinase 3
chr2_+_242498135 0.70 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr5_+_140588269 0.69 ENST00000541609.1
ENST00000239450.2
PCDHB12
protocadherin beta 12
chr9_+_72658490 0.69 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr15_-_89438742 0.69 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr21_-_43373999 0.68 ENST00000380486.3
C2CD2
C2 calcium-dependent domain containing 2
chr12_+_50690489 0.68 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr18_-_53068940 0.68 ENST00000562638.1
TCF4
transcription factor 4
chr2_+_159825143 0.67 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr9_+_101705893 0.67 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr16_-_2059748 0.67 ENST00000562103.1
ENST00000431526.1
ZNF598
zinc finger protein 598
chr1_-_6321035 0.65 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr9_+_33240157 0.65 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr17_-_46799872 0.65 ENST00000290294.3
PRAC1
prostate cancer susceptibility candidate 1
chr22_-_37640456 0.64 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_108991812 0.64 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chr22_-_30642728 0.63 ENST00000403987.3
LIF
leukemia inhibitory factor
chr19_-_17958832 0.62 ENST00000458235.1
JAK3
Janus kinase 3
chr16_+_85932760 0.62 ENST00000565552.1
IRF8
interferon regulatory factor 8
chr19_-_47128294 0.61 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr8_+_38644715 0.61 ENST00000317827.4
ENST00000379931.3
TACC1
transforming, acidic coiled-coil containing protein 1
chr20_+_30225682 0.60 ENST00000376075.3
COX4I2
cytochrome c oxidase subunit IV isoform 2 (lung)
chr10_+_104154229 0.60 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr3_-_3152031 0.59 ENST00000383846.1
ENST00000427088.1
ENST00000446632.2
ENST00000438560.1
IL5RA
interleukin 5 receptor, alpha
chr19_+_17638059 0.59 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr14_+_86401039 0.58 ENST00000557195.1
CTD-2341M24.1
CTD-2341M24.1
chr14_-_69446034 0.58 ENST00000193403.6
ACTN1
actinin, alpha 1
chr22_-_38380543 0.58 ENST00000396884.2
SOX10
SRY (sex determining region Y)-box 10
chr1_-_202130702 0.57 ENST00000309017.3
ENST00000477554.1
ENST00000492451.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr12_-_127256772 0.57 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr6_+_138188351 0.57 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_-_111091948 0.57 ENST00000447165.2
NREP
neuronal regeneration related protein
chrX_+_153059608 0.56 ENST00000370087.1
SSR4
signal sequence receptor, delta
chr12_+_104324112 0.56 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_-_92539614 0.56 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_+_110453514 0.56 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_75428857 0.56 ENST00000198801.5
MOGAT2
monoacylglycerol O-acyltransferase 2
chr19_+_17638041 0.56 ENST00000601861.1
FAM129C
family with sequence similarity 129, member C
chr21_-_44898015 0.55 ENST00000332440.3
LINC00313
long intergenic non-protein coding RNA 313
chr18_-_53068782 0.55 ENST00000569012.1
TCF4
transcription factor 4
chr12_-_40013553 0.55 ENST00000308666.3
ABCD2
ATP-binding cassette, sub-family D (ALD), member 2
chr18_-_71959159 0.55 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr2_+_219745020 0.54 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr4_-_114900126 0.54 ENST00000541197.1
ARSJ
arylsulfatase family, member J
chr1_+_201979743 0.54 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr9_-_136344197 0.54 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr18_-_53068911 0.53 ENST00000537856.3
TCF4
transcription factor 4
chr3_+_52529346 0.53 ENST00000321725.6
STAB1
stabilin 1
chr12_-_54982420 0.52 ENST00000257905.8
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr4_-_74904398 0.52 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr1_+_110453203 0.52 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr7_+_150498783 0.52 ENST00000475536.1
ENST00000468689.1
TMEM176A
transmembrane protein 176A
chr11_+_102188272 0.52 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr3_-_186262166 0.52 ENST00000307944.5
CRYGS
crystallin, gamma S
chr5_-_150521192 0.52 ENST00000523714.1
ENST00000521749.1
ANXA6
annexin A6
chr17_-_40828969 0.51 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr9_-_130517522 0.51 ENST00000373274.3
ENST00000420366.1
SH2D3C
SH2 domain containing 3C
chr1_+_110453462 0.50 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr1_-_202129105 0.50 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_38747172 0.50 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr10_+_124221036 0.50 ENST00000368984.3
HTRA1
HtrA serine peptidase 1
chr12_-_49259643 0.50 ENST00000309739.5
RND1
Rho family GTPase 1
chr3_-_156878482 0.50 ENST00000295925.4
CCNL1
cyclin L1
chrX_+_67913471 0.49 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr12_-_57443886 0.49 ENST00000300119.3
MYO1A
myosin IA
chr6_+_138188551 0.49 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_+_57392684 0.48 ENST00000219235.4
CCL22
chemokine (C-C motif) ligand 22
chr8_-_65711310 0.48 ENST00000310193.3
CYP7B1
cytochrome P450, family 7, subfamily B, polypeptide 1
chr19_+_45504688 0.48 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr6_+_126221034 0.48 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr1_-_202129704 0.47 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr8_+_73449625 0.47 ENST00000523207.1
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
chrX_+_37208540 0.47 ENST00000466533.1
ENST00000542554.1
ENST00000543642.1
ENST00000484460.1
ENST00000449135.2
ENST00000463135.1
ENST00000465127.1
PRRG1
TM4SF2
proline rich Gla (G-carboxyglutamic acid) 1
Uncharacterized protein; cDNA FLJ59144, highly similar to Tetraspanin-7
chr4_-_185275104 0.47 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr4_+_74735102 0.47 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr8_+_72755796 0.46 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr7_+_142423143 0.46 ENST00000390399.3
TRBV27
T cell receptor beta variable 27
chr1_+_110453109 0.46 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_102188224 0.45 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chrX_-_73072534 0.45 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr1_+_95975672 0.44 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr12_+_6309517 0.43 ENST00000382519.4
ENST00000009180.4
CD9
CD9 molecule
chr6_-_36355513 0.43 ENST00000340181.4
ENST00000373737.4
ETV7
ets variant 7
chr9_-_140335789 0.43 ENST00000344119.2
ENST00000371506.2
ENTPD8
ectonucleoside triphosphate diphosphohydrolase 8
chr12_+_6308881 0.43 ENST00000382518.1
ENST00000536586.1
CD9
CD9 molecule
chr1_-_113253977 0.42 ENST00000606505.1
ENST00000605933.1
RP11-426L16.10
Rho-related GTP-binding protein RhoC
chr1_+_207669573 0.42 ENST00000400960.2
ENST00000534202.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chrX_-_153599578 0.42 ENST00000360319.4
ENST00000344736.4
FLNA
filamin A, alpha
chr12_-_55378470 0.41 ENST00000524668.1
ENST00000533607.1
TESPA1
thymocyte expressed, positive selection associated 1
chr6_+_138188378 0.41 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_-_52005009 0.41 ENST00000291707.3
SIGLEC12
sialic acid binding Ig-like lectin 12 (gene/pseudogene)
chr14_+_75988768 0.40 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr5_+_140579162 0.40 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chrX_+_48644962 0.40 ENST00000376670.3
ENST00000376665.3
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr3_-_155461515 0.40 ENST00000399242.2
AC104472.1
CDNA FLJ26134 fis, clone TMS03713; Uncharacterized protein
chr2_-_163099546 0.40 ENST00000447386.1
FAP
fibroblast activation protein, alpha
chr7_+_150498610 0.39 ENST00000461345.1
TMEM176A
transmembrane protein 176A
chr17_-_40829026 0.39 ENST00000412503.1
PLEKHH3
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_-_1356719 0.39 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr19_+_496454 0.39 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr16_-_67978016 0.39 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr12_-_49318715 0.39 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr2_+_176957619 0.39 ENST00000392539.3
HOXD13
homeobox D13
chr16_-_2059797 0.39 ENST00000563630.1
ZNF598
zinc finger protein 598
chr19_+_14142535 0.38 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr11_-_58345569 0.37 ENST00000528954.1
ENST00000528489.1
LPXN
leupaxin
chr4_-_48683188 0.37 ENST00000505759.1
FRYL
FRY-like
chr12_+_56473628 0.36 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_+_207669613 0.36 ENST00000367049.4
ENST00000529814.1
CR1
complement component (3b/4b) receptor 1 (Knops blood group)
chr3_-_151176497 0.36 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr9_+_133259836 0.36 ENST00000455439.2
HMCN2
hemicentin 2
chr22_+_37318082 0.36 ENST00000406230.1
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_+_112939121 0.36 ENST00000441739.1
CTTNBP2NL
CTTNBP2 N-terminal like
chr11_-_75062730 0.35 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr5_+_134181755 0.35 ENST00000504727.1
ENST00000435259.2
ENST00000508791.1
C5orf24
chromosome 5 open reading frame 24
chr8_-_95229531 0.35 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr12_-_54982300 0.34 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_-_113249734 0.34 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr9_+_127539481 0.34 ENST00000373580.3
OLFML2A
olfactomedin-like 2A
chr10_+_102756800 0.34 ENST00000370223.3
LZTS2
leucine zipper, putative tumor suppressor 2
chr15_-_82824843 0.34 ENST00000560826.1
ENST00000559187.1
ENST00000330339.7
RPS17
ribosomal protein S17
chr11_-_75062829 0.33 ENST00000393505.4
ARRB1
arrestin, beta 1
chr4_+_39046615 0.33 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr8_+_101170563 0.33 ENST00000520508.1
ENST00000388798.2
SPAG1
sperm associated antigen 1
chrX_+_37208521 0.33 ENST00000378628.4
PRRG1
proline rich Gla (G-carboxyglutamic acid) 1
chr14_+_75988851 0.33 ENST00000555504.1
BATF
basic leucine zipper transcription factor, ATF-like
chr16_+_89686991 0.33 ENST00000393092.3
DPEP1
dipeptidase 1 (renal)

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.9 2.8 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.5 1.5 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.4 1.3 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)
0.4 1.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.4 2.0 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.4 1.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.3 1.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.3 0.8 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.3 1.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 0.8 GO:0030451 regulation of complement activation, alternative pathway(GO:0030451) negative regulation of complement activation, alternative pathway(GO:0045957)
0.2 2.0 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.8 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 0.6 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 1.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 1.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.2 0.6 GO:0031247 actin rod assembly(GO:0031247)
0.2 2.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.2 0.5 GO:0097187 dentinogenesis(GO:0097187)
0.2 0.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 1.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.6 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 0.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.7 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.4 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.1 4.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 1.0 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.1 6.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:0016999 antibiotic metabolic process(GO:0016999)
0.1 1.1 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 17.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.7 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.7 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.1 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.8 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.1 1.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.8 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.9 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.3 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.1 3.7 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 1.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.4 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.8 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 2.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.8 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.7 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.5 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 1.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.9 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.3 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.9 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.1 0.9 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.4 GO:0042832 defense response to protozoan(GO:0042832)
0.1 1.2 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 1.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.7 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.2 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.8 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.1 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.4 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.3 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 3.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 8.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.8 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.1 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
0.0 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 1.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.6 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.5 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.6 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232) cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0 0.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.3 GO:0030033 microvillus assembly(GO:0030033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.1 GO:0019815 B cell receptor complex(GO:0019815)
0.3 1.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 5.6 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 4.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.4 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
0.1 0.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.4 GO:0031523 Myb complex(GO:0031523)
0.1 0.9 GO:0070552 BRISC complex(GO:0070552)
0.1 0.9 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 0.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.5 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.9 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.8 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 9.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 1.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0098553 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 2.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 3.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 5.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.3 1.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.3 0.9 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 2.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 0.8 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.3 1.3 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.3 0.8 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.3 1.0 GO:0060422 peptidyl-dipeptidase inhibitor activity(GO:0060422)
0.3 2.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 2.8 GO:0016015 morphogen activity(GO:0016015)
0.2 0.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 2.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 1.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.7 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.9 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 24.4 GO:0003823 antigen binding(GO:0003823)
0.1 1.8 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1 3.8 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.1 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 5.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.3 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 1.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235) metallodipeptidase activity(GO:0070573)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.4 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.5 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.6 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 5.0 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 1.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 5.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 2.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 2.6 PID BMP PATHWAY BMP receptor signaling
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID IGF1 PATHWAY IGF1 pathway
0.0 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.8 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 7.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.9 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 2.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.4 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse