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Illumina Body Map 2

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Results for RXRG

Z-value: 1.20

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Transcription factors associated with RXRG

Gene Symbol Gene ID Gene Info
RXRG
ENSG00000143171.8 retinoid X receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RXRGhg19_v2_chr1_-_165414414_1654144330.512.7e-03Click!

Activity profile of RXRG motif

Sorted Z-values of RXRG motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_54378923 3.58 ENST00000303460.4
HOXC10
homeobox C10
chr19_-_49658641 3.53 ENST00000252825.4
HRC
histidine rich calcium binding protein
chr12_-_54982420 3.22 ENST00000257905.8
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr16_+_55357672 2.97 ENST00000290552.7
IRX6
iroquois homeobox 6
chr20_+_43343886 2.91 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr7_+_116166331 2.74 ENST00000393468.1
ENST00000393467.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr14_-_38725573 2.73 ENST00000342213.2
CLEC14A
C-type lectin domain family 14, member A
chr12_+_54378849 2.68 ENST00000515593.1
HOXC10
homeobox C10
chr20_-_44539538 2.46 ENST00000372420.1
PLTP
phospholipid transfer protein
chr15_+_41221536 2.44 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr17_+_7184986 2.36 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr7_+_116139821 2.36 ENST00000393480.2
CAV2
caveolin 2
chr12_+_12878829 2.31 ENST00000326765.6
APOLD1
apolipoprotein L domain containing 1
chr7_+_116165754 2.30 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116139744 2.17 ENST00000343213.2
CAV2
caveolin 2
chr14_-_61190754 2.15 ENST00000216513.4
SIX4
SIX homeobox 4
chr19_-_49658387 2.11 ENST00000595625.1
HRC
histidine rich calcium binding protein
chr19_+_50706866 2.07 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr5_-_138730817 2.05 ENST00000434752.2
PROB1
proline-rich basic protein 1
chr6_+_107811162 2.02 ENST00000317357.5
SOBP
sine oculis binding protein homolog (Drosophila)
chr3_-_38691119 2.01 ENST00000333535.4
ENST00000413689.1
ENST00000443581.1
ENST00000425664.1
ENST00000451551.2
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
chr11_-_86666427 2.01 ENST00000531380.1
FZD4
frizzled family receptor 4
chr1_+_202317815 1.99 ENST00000608999.1
ENST00000336894.4
ENST00000480184.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr10_+_88718314 1.99 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr19_-_17375527 1.94 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr17_-_40575535 1.91 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chrX_+_38420623 1.90 ENST00000378482.2
TSPAN7
tetraspanin 7
chr10_+_88718397 1.86 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr19_+_35630022 1.84 ENST00000589209.1
FXYD1
FXYD domain containing ion transport regulator 1
chr17_-_38256973 1.81 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr22_-_51016433 1.78 ENST00000405237.3
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chrX_+_38420783 1.76 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr5_+_131593364 1.76 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr8_+_144295067 1.75 ENST00000330824.2
GPIHBP1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr3_-_119379427 1.75 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr17_+_39969183 1.74 ENST00000321562.4
FKBP10
FK506 binding protein 10, 65 kDa
chr3_-_119379719 1.72 ENST00000493094.1
POPDC2
popeye domain containing 2
chr1_-_245134273 1.70 ENST00000607453.1
RP11-156E8.1
Uncharacterized protein
chr12_-_54982300 1.69 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr19_-_4517613 1.67 ENST00000301286.3
PLIN4
perilipin 4
chr6_-_46459099 1.65 ENST00000371374.1
RCAN2
regulator of calcineurin 2
chr5_+_80529104 1.64 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
chr5_-_131562935 1.64 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr12_-_57634475 1.64 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr9_-_124991124 1.64 ENST00000394319.4
ENST00000340587.3
LHX6
LIM homeobox 6
chr17_-_73511504 1.60 ENST00000581870.1
CASKIN2
CASK interacting protein 2
chr16_+_222846 1.60 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr17_+_59477233 1.59 ENST00000240328.3
TBX2
T-box 2
chr17_+_42923686 1.59 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr19_+_35630344 1.59 ENST00000455515.2
FXYD1
FXYD domain containing ion transport regulator 1
chr9_-_124990680 1.58 ENST00000541397.2
ENST00000560485.1
LHX6
LIM homeobox 6
chr17_+_39968926 1.58 ENST00000585664.1
ENST00000585922.1
ENST00000429461.1
FKBP10
FK506 binding protein 10, 65 kDa
chr19_+_16999966 1.56 ENST00000599210.1
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_35630628 1.55 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr11_-_46940074 1.52 ENST00000378623.1
ENST00000534404.1
LRP4
low density lipoprotein receptor-related protein 4
chr17_-_73511584 1.47 ENST00000321617.3
CASKIN2
CASK interacting protein 2
chr15_-_56035177 1.44 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr19_-_47922750 1.43 ENST00000331559.5
MEIS3
Meis homeobox 3
chr6_+_43737939 1.42 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr14_+_69726968 1.42 ENST00000553669.1
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr7_-_107643567 1.40 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr3_-_120169828 1.39 ENST00000424703.2
ENST00000469005.1
FSTL1
follistatin-like 1
chr3_+_28390637 1.39 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr7_-_82073031 1.39 ENST00000356253.5
ENST00000423588.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr9_+_124413873 1.38 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr15_-_71146480 1.37 ENST00000299213.8
LARP6
La ribonucleoprotein domain family, member 6
chr17_+_39975455 1.37 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr7_-_82073109 1.36 ENST00000356860.3
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_+_202317855 1.35 ENST00000356764.2
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr15_-_74043816 1.32 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr17_+_39975544 1.32 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr12_+_58003935 1.29 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr1_+_220701740 1.28 ENST00000366917.4
MARK1
MAP/microtubule affinity-regulating kinase 1
chr7_-_107643674 1.28 ENST00000222399.6
LAMB1
laminin, beta 1
chr15_-_75017711 1.28 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr11_-_9113137 1.27 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr11_-_47447767 1.27 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr16_+_28889703 1.26 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr8_-_93115445 1.26 ENST00000523629.1
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_-_13279406 1.26 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chrX_+_135229559 1.26 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr2_+_56411131 1.24 ENST00000407595.2
CCDC85A
coiled-coil domain containing 85A
chr22_+_51176624 1.24 ENST00000216139.5
ENST00000529621.1
ACR
acrosin
chrX_+_135229600 1.24 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr20_+_53092123 1.24 ENST00000262593.5
DOK5
docking protein 5
chr16_+_28889801 1.23 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_-_1587166 1.22 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr2_+_27301435 1.21 ENST00000380320.4
EMILIN1
elastin microfibril interfacer 1
chr7_-_120497178 1.20 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr3_-_66024213 1.20 ENST00000483466.1
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_-_79082867 1.19 ENST00000419488.1
ENST00000354212.4
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr17_+_36584662 1.18 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chrX_+_135229731 1.18 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr17_+_58227287 1.17 ENST00000300900.4
ENST00000591725.1
CA4
carbonic anhydrase IV
chr9_+_137533615 1.17 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr11_-_2162162 1.16 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_-_154710210 1.15 ENST00000274063.4
SFRP2
secreted frizzled-related protein 2
chr19_-_47922373 1.14 ENST00000559524.1
ENST00000557833.1
ENST00000558555.1
ENST00000561293.1
ENST00000441740.2
MEIS3
Meis homeobox 3
chr6_+_30951487 1.13 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr11_-_9113093 1.13 ENST00000450649.2
SCUBE2
signal peptide, CUB domain, EGF-like 2
chr20_+_53092232 1.12 ENST00000395939.1
DOK5
docking protein 5
chr19_-_17375541 1.12 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr14_-_105635090 1.11 ENST00000331782.3
ENST00000347004.2
JAG2
jagged 2
chr11_-_57092381 1.11 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_-_132549506 1.09 ENST00000370828.3
GPC4
glypican 4
chr2_-_175629164 1.08 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr3_-_50340996 1.08 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr1_-_33336414 1.07 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr5_-_131563501 1.07 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr10_+_81892347 1.06 ENST00000372267.2
PLAC9
placenta-specific 9
chr17_-_31404 1.06 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr1_-_1850697 1.05 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
TMEM52
transmembrane protein 52
chr11_+_10326612 1.05 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr16_-_75299884 1.04 ENST00000538440.2
ENST00000418647.3
BCAR1
breast cancer anti-estrogen resistance 1
chr2_-_175629135 1.04 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr1_+_178062855 1.04 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr11_-_47447970 1.03 ENST00000298852.3
ENST00000530912.1
PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chrX_+_149531524 1.01 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr16_-_70719925 1.00 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr9_-_13279563 1.00 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chr2_+_46524537 0.98 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr12_-_48152428 0.97 ENST00000449771.2
ENST00000395358.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr5_+_170288856 0.96 ENST00000523189.1
RANBP17
RAN binding protein 17
chr1_+_7844312 0.96 ENST00000377541.1
PER3
period circadian clock 3
chr19_+_16999654 0.95 ENST00000248076.3
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr11_+_86667117 0.95 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr3_+_125694347 0.95 ENST00000505382.1
ENST00000511082.1
ROPN1B
rhophilin associated tail protein 1B
chr4_+_20255123 0.95 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr14_+_24600484 0.94 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr22_+_31489344 0.93 ENST00000404574.1
SMTN
smoothelin
chr14_-_61191049 0.93 ENST00000556952.3
SIX4
SIX homeobox 4
chr19_-_46000251 0.92 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chr6_+_43738444 0.91 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr17_+_4853442 0.91 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr15_+_74218787 0.91 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr9_-_123342415 0.90 ENST00000349780.4
ENST00000360190.4
ENST00000360822.3
ENST00000359309.3
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr9_-_112260531 0.90 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr1_-_154946792 0.90 ENST00000412170.1
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr17_+_12569472 0.89 ENST00000343344.4
MYOCD
myocardin
chr1_+_199996733 0.89 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr5_+_128301189 0.89 ENST00000395266.1
ENST00000506176.1
SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr17_+_40811283 0.89 ENST00000251412.7
TUBG2
tubulin, gamma 2
chr5_-_132113063 0.88 ENST00000378719.2
SEPT8
septin 8
chr10_-_103454876 0.88 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr7_+_3340989 0.88 ENST00000404826.2
ENST00000389531.3
SDK1
sidekick cell adhesion molecule 1
chr7_+_94536514 0.86 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr17_-_1394940 0.86 ENST00000570984.2
ENST00000361007.2
MYO1C
myosin IC
chr1_-_32210275 0.84 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr10_+_95753714 0.84 ENST00000260766.3
PLCE1
phospholipase C, epsilon 1
chr11_+_72281681 0.84 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr7_-_27239703 0.84 ENST00000222753.4
HOXA13
homeobox A13
chr7_+_94536898 0.84 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr5_-_172755056 0.84 ENST00000520648.1
STC2
stanniocalcin 2
chr18_-_21242833 0.84 ENST00000586087.1
ENST00000592179.1
ANKRD29
ankyrin repeat domain 29
chr12_+_48152774 0.83 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr9_-_132515302 0.83 ENST00000340607.4
PTGES
prostaglandin E synthase
chr11_+_8040739 0.83 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr11_-_11643540 0.82 ENST00000227756.4
GALNT18
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
chr1_+_109642799 0.82 ENST00000602755.1
SCARNA2
small Cajal body-specific RNA 2
chr14_-_89021077 0.82 ENST00000556564.1
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr16_-_11370330 0.81 ENST00000241808.4
ENST00000435245.2
PRM2
protamine 2
chr5_-_37839782 0.81 ENST00000326524.2
ENST00000515058.1
GDNF
glial cell derived neurotrophic factor
chrX_+_149531606 0.81 ENST00000432680.2
MAMLD1
mastermind-like domain containing 1
chr19_-_474880 0.80 ENST00000382696.3
ENST00000315489.4
ODF3L2
outer dense fiber of sperm tails 3-like 2
chr2_+_95963052 0.80 ENST00000295225.5
KCNIP3
Kv channel interacting protein 3, calsenilin
chr1_+_1115056 0.79 ENST00000379288.3
TTLL10
tubulin tyrosine ligase-like family, member 10
chr22_+_18593507 0.79 ENST00000330423.3
TUBA8
tubulin, alpha 8
chr5_+_128300810 0.79 ENST00000262462.4
SLC27A6
solute carrier family 27 (fatty acid transporter), member 6
chr22_+_18593446 0.78 ENST00000316027.6
TUBA8
tubulin, alpha 8
chr1_+_199996702 0.78 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr18_+_56530692 0.78 ENST00000588601.1
ZNF532
zinc finger protein 532
chr3_+_12329358 0.78 ENST00000309576.6
PPARG
peroxisome proliferator-activated receptor gamma
chr6_+_44194762 0.77 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr12_-_102874330 0.77 ENST00000307046.8
IGF1
insulin-like growth factor 1 (somatomedin C)
chr11_-_57089774 0.77 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_-_110612323 0.76 ENST00000383686.2
RP11-553A10.1
Uncharacterized protein
chr19_-_48867291 0.76 ENST00000435956.3
TMEM143
transmembrane protein 143
chr11_+_450255 0.75 ENST00000308020.5
PTDSS2
phosphatidylserine synthase 2
chr17_+_3627185 0.75 ENST00000325418.4
GSG2
germ cell associated 2 (haspin)
chr1_-_149982624 0.74 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr8_-_42397037 0.74 ENST00000342228.3
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr17_+_7210898 0.73 ENST00000572815.1
EIF5A
eukaryotic translation initiation factor 5A
chr12_-_48152611 0.72 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr16_-_2007607 0.72 ENST00000565426.1
RPL3L
ribosomal protein L3-like
chr1_-_31902614 0.72 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr6_-_33267101 0.71 ENST00000497454.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr18_+_56530794 0.71 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532
zinc finger protein 532
chr14_+_24867992 0.71 ENST00000382554.3
NYNRIN
NYN domain and retroviral integrase containing
chr10_-_103603677 0.70 ENST00000358038.3
KCNIP2
Kv channel interacting protein 2
chr1_-_153521714 0.70 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr13_+_103046954 0.70 ENST00000606448.1
FGF14-AS2
FGF14 antisense RNA 2
chr7_+_116312411 0.70 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr11_-_57089671 0.69 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr2_-_242255117 0.69 ENST00000420451.1
ENST00000417540.1
ENST00000310931.4
HDLBP
high density lipoprotein binding protein
chr22_-_30234218 0.69 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2
activating signal cointegrator 1 complex subunit 2
chr12_+_52400719 0.69 ENST00000293662.4
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr10_-_81203972 0.69 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr1_+_156052354 0.69 ENST00000368301.2
LMNA
lamin A/C
chr3_-_46904946 0.69 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_-_36906058 0.68 ENST00000580830.1
PCGF2
polycomb group ring finger 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RXRG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.6 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
1.7 5.0 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
1.5 6.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.9 4.5 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.8 2.5 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.8 2.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.8 3.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.7 2.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.6 5.0 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.6 1.8 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.6 1.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.6 4.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.5 2.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.5 1.6 GO:1901207 mammary placode formation(GO:0060596) regulation of heart looping(GO:1901207)
0.5 1.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.5 2.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.5 2.3 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.4 2.7 GO:0071503 response to heparin(GO:0071503)
0.4 1.3 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.4 1.7 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.4 2.0 GO:1904073 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.4 2.4 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.4 6.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.4 1.1 GO:0060932 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929) His-Purkinje system cell differentiation(GO:0060932)
0.3 1.0 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.3 1.4 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 2.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.3 1.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 0.8 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 3.0 GO:0034465 response to carbon monoxide(GO:0034465)
0.2 2.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 3.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 1.8 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.9 GO:0018277 protein deamination(GO:0018277)
0.2 0.9 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.2 0.7 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.2 0.7 GO:0034059 response to anoxia(GO:0034059)
0.2 1.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 1.7 GO:0007341 penetration of zona pellucida(GO:0007341)
0.2 0.8 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.2 0.5 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.7 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 1.5 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.8 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.2 0.5 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2 0.8 GO:0015862 uridine transport(GO:0015862)
0.1 2.5 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.1 0.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.0 GO:0043129 surfactant homeostasis(GO:0043129)
0.1 0.6 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.4 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 3.3 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.4 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.5 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.7 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.1 0.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.6 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.8 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 1.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.7 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.2 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.1 1.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.1 0.7 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 1.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 0.9 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.5 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.3 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.8 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.3 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.5 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 1.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 2.1 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.8 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.5 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.9 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 0.5 GO:0032910 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.8 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.5 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.5 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 2.7 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:0030047 actin modification(GO:0030047)
0.1 1.3 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 1.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 1.8 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.7 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 2.4 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.8 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 2.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.4 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.5 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.5 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 1.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.5 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.8 GO:0035562 protein desumoylation(GO:0016926) negative regulation of chromatin binding(GO:0035562)
0.0 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 1.2 GO:0006853 carnitine shuttle(GO:0006853)
0.0 4.0 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.7 GO:0015074 DNA integration(GO:0015074)
0.0 0.8 GO:0015886 heme transport(GO:0015886)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 1.0 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 1.0 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0035962 response to interleukin-13(GO:0035962)
0.0 1.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.0 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.0 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 4.8 GO:0005977 glycogen metabolic process(GO:0005977)
0.0 0.7 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.6 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 3.8 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.0 1.3 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886) response to hydrostatic pressure(GO:0051599)
0.0 0.4 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 1.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 1.3 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 1.8 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 1.5 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.0 GO:0090102 cochlea development(GO:0090102)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.3 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.9 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 2.9 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.6 GO:0043586 tongue development(GO:0043586)
0.0 3.3 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.2 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 1.3 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.0 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.0 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.9 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.3 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.7 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 1.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.9 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0 1.0 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 1.5 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 2.1 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.4 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.4 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.6 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.7 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.0 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.6 GO:0046324 regulation of glucose import(GO:0046324)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315) positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.1 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 2.0 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.2 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0032402 melanosome transport(GO:0032402)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.6 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0043257 laminin-8 complex(GO:0043257)
0.5 6.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.5 1.4 GO:1990032 parallel fiber(GO:1990032)
0.4 1.2 GO:0043159 acrosomal matrix(GO:0043159)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.1 GO:0036117 hyaluranon cable(GO:0036117)
0.4 5.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 2.1 GO:0097513 myosin II filament(GO:0097513)
0.3 0.3 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.3 5.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.3 2.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.3 2.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.2 1.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.2 0.9 GO:0045160 myosin I complex(GO:0045160)
0.2 5.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 1.7 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 2.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.2 0.9 GO:0014802 terminal cisterna(GO:0014802)
0.2 2.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 3.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 4.5 GO:0002080 acrosomal membrane(GO:0002080)
0.1 2.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 1.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.5 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 2.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 2.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 1.4 GO:0016600 flotillin complex(GO:0016600)
0.1 2.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 0.7 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.4 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 2.1 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 5.4 GO:0031672 A band(GO:0031672)
0.1 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.5 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:1990742 microvesicle(GO:1990742)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.5 GO:0042587 glycogen granule(GO:0042587)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.2 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 3.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 5.3 GO:0042383 sarcolemma(GO:0042383)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 7.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 1.0 GO:0008305 integrin complex(GO:0008305)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.9 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.1 GO:0032993 protein-DNA complex(GO:0032993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.9 2.7 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.5 2.0 GO:0032184 SUMO polymer binding(GO:0032184)
0.5 2.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.5 2.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 1.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 2.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 3.3 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.3 1.0 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.3 3.0 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.3 2.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.2 GO:0004040 amidase activity(GO:0004040)
0.3 4.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.3 1.3 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.3 1.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.2 1.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 6.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 2.2 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.7 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.2 2.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.2 1.1 GO:0010736 serum response element binding(GO:0010736)
0.2 2.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 0.6 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.6 GO:0070984 SET domain binding(GO:0070984)
0.2 0.7 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.2 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 6.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 1.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.2 0.5 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.4 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 2.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 2.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 3.6 GO:0005112 Notch binding(GO:0005112)
0.1 2.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.4 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.8 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.8 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 2.0 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 3.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 5.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.8 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.8 GO:0050544 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544) DBD domain binding(GO:0050692)
0.1 0.3 GO:0004608 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 2.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 6.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.5 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 2.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.8 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 1.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 0.5 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0031432 titin binding(GO:0031432)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.8 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 11.5 GO:0044325 ion channel binding(GO:0044325)
0.1 6.9 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0050254 rhodopsin kinase activity(GO:0050254)
0.0 1.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 1.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.8 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.3 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.9 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.5 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 3.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 3.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.9 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0070035 ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.0 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 2.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 6.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID IGF1 PATHWAY IGF1 pathway
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 2.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 3.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.7 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 5.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 3.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 5.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 6.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 1.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 3.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 2.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 2.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 2.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 3.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation