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Illumina Body Map 2

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Results for SOX30

Z-value: 0.88

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
ENSG00000039600.6 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079428_1570794520.144.5e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_11548496 3.91 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr12_-_11463353 3.68 ENST00000279575.1
ENST00000535904.1
ENST00000445719.2
proline-rich protein BstNI subfamily 4
chr12_-_11508520 3.38 ENST00000545626.1
ENST00000500254.2
proline-rich protein BstNI subfamily 1
chr12_+_11081828 3.10 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr12_-_11002063 3.00 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
proline rich 4 (lacrimal)
chr12_-_11036844 2.55 ENST00000428168.2
proline-rich protein HaeIII subfamily 1
chr12_-_11422630 2.49 ENST00000381842.3
ENST00000538488.1
proline-rich protein BstNI subfamily 3
chr12_-_11422739 2.04 ENST00000279573.7
proline-rich protein BstNI subfamily 3
chrY_+_15016013 2.01 ENST00000360160.4
ENST00000454054.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_+_181429704 1.62 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr10_-_28270795 1.48 ENST00000545014.1
armadillo repeat containing 4
chr4_+_77356248 1.40 ENST00000296043.6
shroom family member 3
chr2_-_158182410 1.35 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr5_-_82969405 1.30 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr7_+_100770328 1.20 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_-_165555200 1.05 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr7_-_121944491 1.00 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZ family zinc finger 1
chr8_-_70016408 0.97 ENST00000518540.1
RP11-600K15.1
chr5_+_139175380 0.93 ENST00000274710.3
pleckstrin and Sec7 domain containing 2
chr3_-_19988462 0.93 ENST00000344838.4
EF-hand domain family, member B
chr1_+_47489240 0.88 ENST00000371901.3
cytochrome P450, family 4, subfamily X, polypeptide 1
chr6_+_12290586 0.87 ENST00000379375.5
endothelin 1
chr11_+_63057412 0.84 ENST00000544661.1
solute carrier family 22, member 10
chr16_+_87636474 0.84 ENST00000284262.2
junctophilin 3
chrX_-_24690771 0.82 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr5_-_82969363 0.81 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr2_-_158182322 0.78 ENST00000420719.2
ENST00000409216.1
ermin, ERM-like protein
chr14_+_100070869 0.77 ENST00000502101.2
RP11-543C4.1
chr1_-_204463829 0.75 ENST00000429009.1
ENST00000415899.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr1_-_26231589 0.74 ENST00000374291.1
stathmin 1
chr17_-_38821373 0.68 ENST00000394052.3
keratin 222
chr6_+_126240442 0.68 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
nuclear receptor coactivator 7
chr3_-_167191814 0.66 ENST00000466903.1
ENST00000264677.4
serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_-_201476274 0.64 ENST00000340006.2
cysteine and glycine-rich protein 1
chr2_+_179184955 0.63 ENST00000315022.2
oxysterol binding protein-like 6
chrX_+_114874727 0.63 ENST00000543070.1
plastin 3
chr2_-_166702601 0.60 ENST00000428888.1
AC009495.4
chr8_+_24151553 0.59 ENST00000265769.4
ENST00000540823.1
ENST00000397649.3
ADAM metallopeptidase domain 28
chr1_-_201476220 0.59 ENST00000526723.1
ENST00000524951.1
cysteine and glycine-rich protein 1
chr12_-_10251576 0.58 ENST00000315330.4
C-type lectin domain family 1, member A
chr13_+_98795664 0.58 ENST00000376581.5
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr12_-_10251539 0.58 ENST00000420265.2
C-type lectin domain family 1, member A
chr12_-_10251603 0.57 ENST00000457018.2
C-type lectin domain family 1, member A
chr12_-_10588539 0.44 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr9_+_103235365 0.44 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_-_70725856 0.44 ENST00000226444.3
sulfotransferase family 1E, estrogen-preferring, member 1
chr12_-_66317967 0.43 ENST00000601398.1
Uncharacterized protein
chr5_+_140729649 0.41 ENST00000523390.1
protocadherin gamma subfamily B, 1
chr1_+_185703513 0.41 ENST00000271588.4
ENST00000367492.2
hemicentin 1
chr13_+_110958124 0.39 ENST00000400163.2
collagen, type IV, alpha 2
chr4_-_176733897 0.38 ENST00000393658.2
glycoprotein M6A
chr5_+_140739537 0.38 ENST00000522605.1
protocadherin gamma subfamily B, 2
chr5_+_170288856 0.38 ENST00000523189.1
RAN binding protein 17
chr10_-_62060232 0.38 ENST00000503925.1
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_82792215 0.37 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr5_+_140772381 0.36 ENST00000398604.2
protocadherin gamma subfamily A, 8
chr5_+_140235469 0.36 ENST00000506939.2
ENST00000307360.5
protocadherin alpha 10
chr11_-_85430356 0.35 ENST00000526999.1
synaptotagmin-like 2
chr5_+_38148582 0.35 ENST00000508853.1
CTD-2207A17.1
chr15_+_69857515 0.35 ENST00000559477.1
RP11-279F6.1
chr1_-_243418621 0.34 ENST00000366544.1
ENST00000366543.1
centrosomal protein 170kDa
chr1_-_85930246 0.33 ENST00000426972.3
dimethylarginine dimethylaminohydrolase 1
chr10_-_124459284 0.33 ENST00000432000.1
ENST00000329446.4
chromosome 10 open reading frame 120
chr11_-_85430163 0.31 ENST00000529581.1
ENST00000533577.1
synaptotagmin-like 2
chr6_-_49712123 0.31 ENST00000263045.4
cysteine-rich secretory protein 3
chr6_-_11779174 0.30 ENST00000379413.2
androgen-dependent TFPI-regulating protein
chr8_+_24151620 0.30 ENST00000437154.2
ADAM metallopeptidase domain 28
chr4_-_87028478 0.30 ENST00000515400.1
ENST00000395157.3
mitogen-activated protein kinase 10
chr8_-_49533521 0.28 ENST00000523038.1
RP11-567J20.1
chr11_-_123756334 0.28 ENST00000528595.1
ENST00000375026.2
transmembrane protein 225
chr1_+_240255166 0.27 ENST00000319653.9
formin 2
chr11_-_85430204 0.26 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chrX_+_102192200 0.25 ENST00000218249.5
RAB40A, member RAS oncogene family-like
chr8_-_82024290 0.25 ENST00000220597.4
phosphoprotein associated with glycosphingolipid microdomains 1
chr1_+_228337553 0.25 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr12_+_80750134 0.25 ENST00000546620.1
otogelin-like
chr12_+_27623565 0.25 ENST00000535986.1
single-pass membrane protein with coiled-coil domains 2
chr9_-_74383302 0.23 ENST00000377066.5
transmembrane protein 2
chr2_+_143635067 0.23 ENST00000264170.4
kynureninase
chr1_-_243418344 0.23 ENST00000366542.1
centrosomal protein 170kDa
chr20_-_5426332 0.23 ENST00000420529.1
long intergenic non-protein coding RNA 658
chr6_+_22146851 0.22 ENST00000606197.1
cancer susceptibility candidate 15 (non-protein coding)
chr16_+_20499024 0.22 ENST00000593357.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr3_-_57583130 0.21 ENST00000303436.6
ADP-ribosylation factor 4
chr5_-_160279207 0.20 ENST00000327245.5
ATPase, class V, type 10B
chr6_-_11779014 0.20 ENST00000229583.5
androgen-dependent TFPI-regulating protein
chr1_-_167883353 0.19 ENST00000545172.1
adenylate cyclase 10 (soluble)
chr12_-_99288986 0.19 ENST00000552407.1
ENST00000551613.1
ENST00000548447.1
ENST00000546364.3
ENST00000552748.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_35415719 0.19 ENST00000474362.1
ENST00000374721.3
cAMP responsive element modulator
chr10_+_35415978 0.19 ENST00000429130.3
ENST00000469949.2
ENST00000460270.1
cAMP responsive element modulator
chr13_-_25754077 0.18 ENST00000413501.1
AMER2 antisense RNA 1 (head to head)
chr1_-_167883327 0.17 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
adenylate cyclase 10 (soluble)
chr1_-_198906528 0.17 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr1_-_200379180 0.16 ENST00000294740.3
zinc finger protein 281
chr3_+_19988566 0.16 ENST00000273047.4
RAB5A, member RAS oncogene family
chr20_-_62610982 0.16 ENST00000369886.3
ENST00000450107.1
sterile alpha motif domain containing 10
chr20_+_30555805 0.16 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr11_-_85430088 0.15 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr6_-_89927151 0.14 ENST00000454853.2
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr11_+_128563652 0.14 ENST00000527786.2
Fli-1 proto-oncogene, ETS transcription factor
chr10_+_35416090 0.14 ENST00000354759.3
cAMP responsive element modulator
chr5_-_146461027 0.13 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
protein phosphatase 2, regulatory subunit B, beta
chr1_-_200379129 0.13 ENST00000367353.1
zinc finger protein 281
chr2_-_169769787 0.12 ENST00000451987.1
SPC25, NDC80 kinetochore complex component
chr10_+_35416223 0.11 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr1_-_243418650 0.10 ENST00000522995.1
centrosomal protein 170kDa
chr1_+_74701062 0.10 ENST00000326637.3
TNNI3 interacting kinase
chr14_-_90420862 0.09 ENST00000556005.1
ENST00000555872.1
EF-hand calcium binding domain 11
chr10_-_61122934 0.08 ENST00000512919.1
family with sequence similarity 13, member C
chr7_-_142176790 0.08 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr11_+_63137251 0.07 ENST00000310969.4
ENST00000279178.3
solute carrier family 22 (organic anion transporter), member 9
chr15_+_93426514 0.07 ENST00000556722.1
chromodomain helicase DNA binding protein 2
chr4_+_17516788 0.07 ENST00000511148.2
clarin 2
chr5_-_141338627 0.07 ENST00000231484.3
protocadherin 12
chr4_+_71457970 0.07 ENST00000322937.6
ameloblastin (enamel matrix protein)
chr4_-_186570679 0.07 ENST00000451974.1
sorbin and SH3 domain containing 2
chr3_+_19988736 0.07 ENST00000443878.1
RAB5A, member RAS oncogene family
chr12_+_93096759 0.07 ENST00000544406.2
chromosome 12 open reading frame 74
chr17_+_7323634 0.06 ENST00000323675.3
spermatid maturation 1
chr15_+_76629064 0.06 ENST00000290759.4
ISL LIM homeobox 2
chr14_+_101299520 0.06 ENST00000455531.1
maternally expressed 3 (non-protein coding)
chr12_-_49581152 0.06 ENST00000550811.1
tubulin, alpha 1a
chr22_-_30970560 0.06 ENST00000402369.1
ENST00000406361.1
galactose-3-O-sulfotransferase 1
chr6_-_134639180 0.06 ENST00000367858.5
serum/glucocorticoid regulated kinase 1
chr4_+_71458012 0.05 ENST00000449493.2
ameloblastin (enamel matrix protein)
chr14_+_36295504 0.04 ENST00000216807.7
breast cancer metastasis-suppressor 1-like
chr14_-_90421028 0.03 ENST00000267544.9
ENST00000316738.7
ENST00000538485.2
ENST00000556609.1
EF-hand calcium binding domain 11
chr6_-_134639235 0.02 ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr6_-_161085291 0.02 ENST00000316300.5
lipoprotein, Lp(a)
chr1_+_244998602 0.02 ENST00000411948.2
COX20 cytochrome C oxidase assembly factor
chrX_-_117107542 0.02 ENST00000371878.1
kelch-like family member 13
chr17_-_73149921 0.02 ENST00000481647.1
ENST00000470924.1
hematological and neurological expressed 1
chr1_+_244998918 0.01 ENST00000366528.3
COX20 cytochrome C oxidase assembly factor
chr1_+_149239529 0.00 ENST00000457216.2
RP11-403I13.4

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0001300 chronological cell aging(GO:0001300)
0.4 1.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.2 0.9 GO:0060584 nitric oxide transport(GO:0030185) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 1.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 1.6 GO:0001714 endodermal cell fate specification(GO:0001714)
0.1 0.4 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 1.5 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 0.3 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 1.6 GO:0045176 apical protein localization(GO:0045176)
0.1 1.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.8 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.9 GO:0015747 urate transport(GO:0015747)
0.0 4.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 3.0 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 1.2 GO:0070527 platelet aggregation(GO:0070527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 2.1 GO:0033269 internode region of axon(GO:0033269)
0.1 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 1.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.2 0.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.8 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.7 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 1.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.9 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.9 GO:0070330 aromatase activity(GO:0070330)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.8 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 1.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 7.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors