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Illumina Body Map 2

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Results for TCF7

Z-value: 1.17

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Transcription factors associated with TCF7

Gene Symbol Gene ID Gene Info
TCF7
ENSG00000081059.15 transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7hg19_v2_chr5_+_133477868_133477885-0.593.3e-04Click!

Activity profile of TCF7 motif

Sorted Z-values of TCF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_68100989 4.41 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_+_133879193 4.38 ENST00000377869.1
ENST00000220616.4
TG
thyroglobulin
chr2_-_217560248 4.36 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr8_-_119964434 3.70 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr4_-_186682716 3.44 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_79472365 3.37 ENST00000370742.3
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr10_+_99332198 3.05 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chr2_+_234621551 3.01 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_-_16345245 2.87 ENST00000311890.9
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr18_-_56296182 2.74 ENST00000361673.3
ALPK2
alpha-kinase 2
chr1_-_151345159 2.74 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1
selenium binding protein 1
chr7_+_94023873 2.65 ENST00000297268.6
COL1A2
collagen, type I, alpha 2
chr5_-_16936340 2.54 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr14_+_85996471 2.50 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr1_+_169079823 2.49 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_151344172 2.42 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3
Rho family GTPase 3
chr7_-_107643567 2.37 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1
laminin, beta 1
chr17_+_68101117 2.36 ENST00000587698.1
ENST00000587892.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr7_-_107643674 2.32 ENST00000222399.6
LAMB1
laminin, beta 1
chr17_+_31255165 2.27 ENST00000578289.1
ENST00000439138.1
TMEM98
transmembrane protein 98
chr1_+_110009215 2.25 ENST00000369872.3
SYPL2
synaptophysin-like 2
chr14_+_32798462 2.25 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr15_+_74466012 2.22 ENST00000249842.3
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr17_+_72428218 2.14 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_31255023 2.13 ENST00000395149.2
ENST00000261713.4
TMEM98
transmembrane protein 98
chr2_+_1417228 2.13 ENST00000382269.3
ENST00000337415.3
ENST00000345913.4
ENST00000346956.3
ENST00000349624.3
ENST00000539820.1
ENST00000329066.4
ENST00000382201.3
TPO
thyroid peroxidase
chr14_+_32798547 2.13 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr7_+_73868439 2.10 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr8_+_70476088 2.09 ENST00000525999.1
SULF1
sulfatase 1
chrX_+_38420783 2.07 ENST00000422612.2
ENST00000286824.6
ENST00000545599.1
TSPAN7
tetraspanin 7
chr9_-_130639997 2.06 ENST00000373176.1
AK1
adenylate kinase 1
chr2_+_88367299 2.02 ENST00000419482.2
ENST00000444564.2
SMYD1
SET and MYND domain containing 1
chr1_-_116311323 1.97 ENST00000456138.2
CASQ2
calsequestrin 2 (cardiac muscle)
chr14_+_85996507 1.96 ENST00000554746.1
FLRT2
fibronectin leucine rich transmembrane protein 2
chr2_-_242842587 1.95 ENST00000404031.1
AC131097.4
Protein LOC285095
chr2_+_88367368 1.93 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr12_+_101988627 1.89 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr8_+_30244580 1.89 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr2_-_88427568 1.86 ENST00000393750.3
ENST00000295834.3
FABP1
fatty acid binding protein 1, liver
chr12_+_101988774 1.83 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr20_+_57875457 1.82 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr2_+_69240302 1.81 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr15_-_93632421 1.75 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr17_+_72428266 1.74 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_+_48610074 1.72 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chrX_-_15332665 1.71 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr2_-_86564776 1.68 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr5_-_36301984 1.67 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr9_-_35691017 1.65 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr7_+_140774032 1.63 ENST00000565468.1
TMEM178B
transmembrane protein 178B
chr8_-_124665190 1.63 ENST00000325995.7
KLHL38
kelch-like family member 38
chr1_-_110933611 1.59 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr7_-_27213893 1.58 ENST00000283921.4
HOXA10
homeobox A10
chr6_-_29527702 1.57 ENST00000377050.4
UBD
ubiquitin D
chr17_+_31254892 1.55 ENST00000394642.3
ENST00000579849.1
TMEM98
transmembrane protein 98
chr19_+_45281118 1.54 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr15_+_36871983 1.54 ENST00000437989.2
ENST00000569302.1
C15orf41
chromosome 15 open reading frame 41
chr10_-_61122220 1.53 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
FAM13C
family with sequence similarity 13, member C
chr2_+_234580525 1.50 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_+_159570722 1.49 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr1_-_110933663 1.47 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr5_+_150040403 1.47 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr16_-_73082274 1.44 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr2_+_189157536 1.44 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr5_+_147648393 1.43 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr5_+_140235469 1.41 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr11_-_8615488 1.41 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33
serine/threonine kinase 33
chr6_+_125540951 1.41 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr2_+_108994633 1.38 ENST00000409309.3
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr11_-_8615687 1.38 ENST00000534493.1
ENST00000422559.2
STK33
serine/threonine kinase 33
chr11_-_8615720 1.38 ENST00000358872.3
ENST00000454443.2
STK33
serine/threonine kinase 33
chr10_+_52750930 1.36 ENST00000401604.2
PRKG1
protein kinase, cGMP-dependent, type I
chr1_+_185703513 1.35 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr1_+_22138758 1.33 ENST00000344642.2
ENST00000543870.1
LDLRAD2
low density lipoprotein receptor class A domain containing 2
chr2_-_238499337 1.29 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr11_+_100862811 1.29 ENST00000303130.2
TMEM133
transmembrane protein 133
chr5_-_137610300 1.28 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr2_+_234580499 1.28 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr3_+_14860469 1.28 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr3_+_178276488 1.28 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr2_-_86564740 1.27 ENST00000540790.1
ENST00000428491.1
REEP1
receptor accessory protein 1
chr20_+_39969519 1.26 ENST00000373257.3
LPIN3
lipin 3
chr15_+_36871806 1.26 ENST00000566621.1
ENST00000564586.1
C15orf41
chromosome 15 open reading frame 41
chr5_-_137610254 1.25 ENST00000378362.3
GFRA3
GDNF family receptor alpha 3
chr2_-_179659669 1.25 ENST00000436599.1
TTN
titin
chr7_-_16840820 1.25 ENST00000450569.1
AGR2
anterior gradient 2
chr7_+_134576317 1.24 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr7_+_134576151 1.24 ENST00000393118.2
CALD1
caldesmon 1
chr18_+_6729698 1.23 ENST00000383472.4
ARHGAP28
Rho GTPase activating protein 28
chr2_+_159651821 1.21 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr7_-_135433534 1.21 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chr8_-_17579726 1.18 ENST00000381861.3
MTUS1
microtubule associated tumor suppressor 1
chr6_+_43968306 1.18 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr11_+_7506584 1.18 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr17_+_48611853 1.17 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
EPN3
epsin 3
chr7_+_55086703 1.16 ENST00000455089.1
ENST00000342916.3
ENST00000344576.2
ENST00000420316.2
EGFR
epidermal growth factor receptor
chr14_-_23624511 1.16 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr18_-_24445729 1.15 ENST00000383168.4
AQP4
aquaporin 4
chr21_+_17553910 1.13 ENST00000428669.2
LINC00478
long intergenic non-protein coding RNA 478
chr3_-_167813672 1.13 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr17_+_75542997 1.11 ENST00000592651.1
ENST00000590398.1
RP11-13K12.1
RP11-13K12.1
chr7_+_23286182 1.11 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr6_-_112575687 1.10 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr2_-_238499303 1.10 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr2_+_220309379 1.10 ENST00000451076.1
SPEG
SPEG complex locus
chr10_-_69455873 1.09 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr5_+_140579162 1.09 ENST00000536699.1
ENST00000354757.3
PCDHB11
protocadherin beta 11
chr6_+_112408768 1.09 ENST00000368656.2
ENST00000604268.1
FAM229B
family with sequence similarity 229, member B
chr6_-_112575912 1.09 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4
laminin, alpha 4
chr10_+_54074033 1.08 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chrX_-_117119243 1.08 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr10_-_61513201 1.07 ENST00000414264.1
ENST00000594536.1
LINC00948
long intergenic non-protein coding RNA 948
chr13_+_36920569 1.07 ENST00000379848.2
SPG20OS
SPG20 opposite strand
chr2_+_155555201 1.04 ENST00000544049.1
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr1_+_59762642 1.03 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr13_+_30002741 1.01 ENST00000380808.2
MTUS2
microtubule associated tumor suppressor candidate 2
chr10_+_75668916 1.00 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr9_-_21187598 1.00 ENST00000421715.1
IFNA4
interferon, alpha 4
chr19_+_13135439 1.00 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_-_8615507 0.99 ENST00000431279.2
ENST00000418597.1
STK33
serine/threonine kinase 33
chr5_+_140705777 0.99 ENST00000606901.1
ENST00000606674.1
AC005618.6
AC005618.6
chr3_+_35681728 0.98 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr5_+_34757309 0.98 ENST00000397449.1
RAI14
retinoic acid induced 14
chr5_+_140165876 0.97 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr11_+_7506713 0.97 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr4_+_69917078 0.97 ENST00000502942.1
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr12_+_108523133 0.97 ENST00000547525.1
WSCD2
WSC domain containing 2
chr2_-_172750733 0.96 ENST00000392592.4
ENST00000422440.2
SLC25A12
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr22_+_39052632 0.96 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr22_+_29279552 0.96 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr10_+_19777984 0.95 ENST00000377265.3
ENST00000455457.2
C10orf112
MAM and LDL receptor class A domain containing 1
chr1_+_244998918 0.93 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr19_+_50084561 0.93 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr4_+_154125565 0.93 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr11_+_7506837 0.93 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr2_-_241195452 0.92 ENST00000457178.1
AC124861.1
AC124861.1
chr18_+_32455201 0.92 ENST00000590831.2
DTNA
dystrobrevin, alpha
chr1_-_155162658 0.92 ENST00000368389.2
ENST00000368396.4
ENST00000343256.5
ENST00000342482.4
ENST00000368398.3
ENST00000368390.3
ENST00000337604.5
ENST00000368392.3
ENST00000438413.1
ENST00000368393.3
ENST00000457295.2
ENST00000338684.5
ENST00000368395.1
MUC1
mucin 1, cell surface associated
chr1_-_213020991 0.92 ENST00000332912.3
C1orf227
chromosome 1 open reading frame 227
chr1_-_209824643 0.91 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr11_-_57092381 0.90 ENST00000358252.3
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_+_35681081 0.89 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_-_231989808 0.89 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr6_+_32146131 0.89 ENST00000375094.3
RNF5
ring finger protein 5, E3 ubiquitin protein ligase
chr14_+_21214039 0.88 ENST00000326842.2
EDDM3A
epididymal protein 3A
chr13_+_102104952 0.87 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr1_-_153029980 0.87 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr10_+_52833883 0.85 ENST00000373980.4
PRKG1
protein kinase, cGMP-dependent, type I
chr19_+_41256764 0.85 ENST00000243563.3
ENST00000601253.1
ENST00000597353.1
ENST00000599362.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr8_+_95653840 0.85 ENST00000520385.1
ESRP1
epithelial splicing regulatory protein 1
chr4_+_95972822 0.84 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr6_-_25874440 0.84 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr4_+_87515454 0.82 ENST00000427191.2
ENST00000436978.1
ENST00000502971.1
PTPN13
protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
chr4_-_52904425 0.82 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr22_-_39052300 0.82 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr13_+_102142296 0.80 ENST00000376162.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_+_53343171 0.80 ENST00000430986.2
HLF
hepatic leukemia factor
chr6_-_112575758 0.78 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr6_+_43265992 0.78 ENST00000449231.1
ENST00000372589.3
ENST00000372585.5
SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr5_-_160365601 0.78 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1
RP11-109J4.1
chr10_-_99393208 0.77 ENST00000307450.6
MORN4
MORN repeat containing 4
chr12_+_6309963 0.76 ENST00000382515.2
CD9
CD9 molecule
chrX_-_138287168 0.76 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr2_-_99871570 0.75 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr1_+_244998602 0.74 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr1_-_75198940 0.74 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr16_-_8622226 0.74 ENST00000568335.1
TMEM114
transmembrane protein 114
chr8_-_6914251 0.73 ENST00000330590.2
DEFA5
defensin, alpha 5, Paneth cell-specific
chr7_-_135433460 0.73 ENST00000415751.1
FAM180A
family with sequence similarity 180, member A
chr1_-_75198495 0.73 ENST00000441120.1
CRYZ
crystallin, zeta (quinone reductase)
chr17_-_63557309 0.73 ENST00000580513.1
AXIN2
axin 2
chr19_-_49339080 0.73 ENST00000595764.1
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chrX_+_102883620 0.73 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr1_+_68150744 0.73 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr7_-_36406750 0.72 ENST00000453212.1
ENST00000415803.2
ENST00000440378.1
ENST00000431396.1
ENST00000317020.6
ENST00000436884.1
KIAA0895
KIAA0895
chr1_-_75198681 0.72 ENST00000370872.3
ENST00000370871.3
ENST00000340866.5
ENST00000370870.1
CRYZ
crystallin, zeta (quinone reductase)
chr17_+_48503519 0.71 ENST00000300441.4
ENST00000541920.1
ENST00000506582.1
ENST00000504392.1
ENST00000427954.2
ACSF2
acyl-CoA synthetase family member 2
chr10_+_115999089 0.71 ENST00000392982.3
VWA2
von Willebrand factor A domain containing 2
chr8_-_42358742 0.71 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr17_+_53343577 0.71 ENST00000573945.1
HLF
hepatic leukemia factor
chr11_-_64013288 0.71 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_+_166326157 0.70 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr17_-_63556414 0.68 ENST00000585045.1
AXIN2
axin 2
chr3_-_169487617 0.67 ENST00000330368.2
ACTRT3
actin-related protein T3
chr12_+_27677085 0.67 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr9_+_109685630 0.67 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr4_-_85419603 0.67 ENST00000295886.4
NKX6-1
NK6 homeobox 1
chr10_-_62332357 0.66 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_13135386 0.65 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr10_+_104629199 0.65 ENST00000369880.3
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr11_-_76155618 0.65 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr2_+_177134201 0.65 ENST00000452865.1
MTX2
metaxin 2
chr12_-_130529501 0.65 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
RP11-474D1.4
RP11-474D1.3
chr7_-_143929936 0.64 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr6_+_54172653 0.63 ENST00000370869.3
TINAG
tubulointerstitial nephritis antigen
chr2_+_108994466 0.63 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr12_-_71003568 0.62 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr20_+_57875658 0.62 ENST00000371025.3
EDN3
endothelin 3
chr9_+_113431029 0.62 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
MUSK
muscle, skeletal, receptor tyrosine kinase
chr14_-_21502944 0.61 ENST00000382951.3
RNASE13
ribonuclease, RNase A family, 13 (non-active)

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
1.2 3.7 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.9 4.7 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 4.5 GO:0070980 biphenyl catabolic process(GO:0070980)
0.7 4.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 1.8 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.5 4.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 2.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 1.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.5 1.4 GO:0090381 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.4 2.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.4 1.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.4 2.5 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.3 2.4 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.3 4.4 GO:0015705 iodide transport(GO:0015705)
0.3 1.2 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.3 2.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 0.9 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 1.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.3 1.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 0.9 GO:1904482 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.2 5.0 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.2 0.7 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.2 1.3 GO:0051552 flavone metabolic process(GO:0051552)
0.2 1.7 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.2 1.0 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.2 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.2 0.2 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.2 0.5 GO:1904617 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 2.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.2 3.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 0.8 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 2.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 1.6 GO:0070842 aggresome assembly(GO:0070842)
0.1 2.6 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.5 GO:0003193 pulmonary valve formation(GO:0003193) visceral motor neuron differentiation(GO:0021524) foramen ovale closure(GO:0035922)
0.1 0.9 GO:0006740 NADPH regeneration(GO:0006740)
0.1 1.2 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 2.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.1 0.5 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.8 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.6 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 2.0 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.6 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.1 0.7 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 4.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 2.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.1 6.5 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0018277 protein deamination(GO:0018277)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.4 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.7 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.9 GO:0034605 cellular response to heat(GO:0034605)
0.1 1.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.9 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.5 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 2.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 3.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.2 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.1 1.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 2.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 1.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 1.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 1.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.6 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.1 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.0 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.7 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.9 GO:0007320 insemination(GO:0007320)
0.1 0.8 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 2.5 GO:0048485 sympathetic nervous system development(GO:0048485)
0.1 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.6 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.3 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.5 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 1.6 GO:0060065 uterus development(GO:0060065)
0.0 0.4 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 1.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.6 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0070827 chromatin maintenance(GO:0070827)
0.0 1.2 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.0 0.5 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.8 GO:0030913 fusion of sperm to egg plasma membrane(GO:0007342) paranodal junction assembly(GO:0030913)
0.0 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 1.1 GO:0006833 water transport(GO:0006833)
0.0 0.4 GO:0007512 adult heart development(GO:0007512)
0.0 1.1 GO:0042692 muscle cell differentiation(GO:0042692)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 1.2 GO:0030239 myofibril assembly(GO:0030239)
0.0 0.1 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.0 1.8 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 2.4 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 2.3 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 4.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 1.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 1.8 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 1.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.5 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 2.9 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.4 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.5 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.0 0.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.4 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 1.1 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.6 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0019627 urea metabolic process(GO:0019627)
0.0 0.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0043257 laminin-8 complex(GO:0043257)
0.9 2.6 GO:0005584 collagen type I trimer(GO:0005584)
0.4 4.4 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 1.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.4 6.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 3.0 GO:0030478 actin cap(GO:0030478)
0.2 4.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 4.3 GO:0032982 myosin filament(GO:0032982)
0.1 1.9 GO:0045179 apical cortex(GO:0045179)
0.1 2.4 GO:0032433 filopodium tip(GO:0032433)
0.1 3.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 4.4 GO:0005605 basal lamina(GO:0005605)
0.1 2.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 0.3 GO:0035841 new growing cell tip(GO:0035841)
0.1 3.1 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.6 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 2.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.1 4.4 GO:0016235 aggresome(GO:0016235)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 3.0 GO:0000791 euchromatin(GO:0000791)
0.1 1.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.2 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 7.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.7 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.9 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.8 GO:0001533 cornified envelope(GO:0001533)
0.0 0.4 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.4 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.2 GO:0030018 Z disc(GO:0030018)
0.0 1.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 6.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 7.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.7 2.9 GO:1990175 EH domain binding(GO:1990175)
0.5 3.5 GO:0031849 olfactory receptor binding(GO:0031849)
0.5 2.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 3.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 2.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.3 1.0 GO:0019150 D-ribulokinase activity(GO:0019150)
0.3 2.2 GO:0070404 NADH binding(GO:0070404)
0.3 4.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 2.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 0.9 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.3 1.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.3 6.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.5 GO:0051373 FATZ binding(GO:0051373)
0.2 2.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 1.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 1.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 2.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 4.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 4.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 3.7 GO:0031432 titin binding(GO:0031432)
0.2 0.9 GO:0070905 serine binding(GO:0070905)
0.2 2.0 GO:0019534 toxin transporter activity(GO:0019534)
0.1 6.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 2.7 GO:0008430 selenium binding(GO:0008430)
0.1 2.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.5 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 3.5 GO:0031005 filamin binding(GO:0031005)
0.1 0.5 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.1 1.2 GO:0031433 telethonin binding(GO:0031433)
0.1 1.1 GO:0045545 syndecan binding(GO:0045545)
0.1 1.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 2.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1 1.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.8 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.8 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.6 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.1 1.5 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.2 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.1 2.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.2 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 3.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 3.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 1.2 GO:0070513 death domain binding(GO:0070513)
0.1 8.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 4.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.7 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 1.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.8 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 2.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 1.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 4.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.6 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.6 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 1.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.6 GO:0000146 microfilament motor activity(GO:0000146)
0.0 1.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.7 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 9.2 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.7 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.7 ST ADRENERGIC Adrenergic Pathway
0.0 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.2 PID BMP PATHWAY BMP receptor signaling
0.0 3.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.6 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 5.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 6.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 4.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 5.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 2.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 7.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME DEFENSINS Genes involved in Defensins
0.0 1.8 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane