Project

Illumina Body Map 2

Navigation
Downloads

Results for TCF7L1

Z-value: 1.09

Motif logo

Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
ENSG00000152284.4 transcription factor 7 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg19_v2_chr2_+_85360499_85360598-0.551.0e-03Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_109090106 5.60 ENST00000379951.2
lymphoid enhancer-binding factor 1
chr17_-_38020392 5.10 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKAROS family zinc finger 3 (Aiolos)
chr17_-_38020379 4.84 ENST00000351680.3
ENST00000346243.3
ENST00000350532.3
ENST00000467757.1
ENST00000439016.2
IKAROS family zinc finger 3 (Aiolos)
chr4_-_109089573 4.55 ENST00000265165.1
lymphoid enhancer-binding factor 1
chr1_-_200992827 4.51 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr9_-_35650900 4.16 ENST00000259608.3
signaling threshold regulating transmembrane adaptor 1
chr5_+_133450365 4.10 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
transcription factor 7 (T-cell specific, HMG-box)
chr8_+_22019168 3.87 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
surfactant protein C
chr5_-_157002775 3.53 ENST00000257527.4
ADAM metallopeptidase domain 19
chr5_-_157002749 3.40 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM metallopeptidase domain 19
chr17_-_39093672 3.35 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
keratin 23 (histone deacetylase inducible)
chr7_-_105926058 2.96 ENST00000417537.1
nicotinamide phosphoribosyltransferase
chr21_-_46330545 2.91 ENST00000320216.6
ENST00000397852.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr21_+_30671690 2.91 ENST00000399921.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_+_22362613 2.90 ENST00000390438.2
T cell receptor alpha variable 8-4
chr14_+_75746664 2.90 ENST00000557139.1
FBJ murine osteosarcoma viral oncogene homolog
chr14_-_65409502 2.90 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr12_-_54694807 2.87 ENST00000435572.2
nuclear factor, erythroid 2
chr17_+_75447326 2.79 ENST00000591088.1
septin 9
chr10_-_14613968 2.77 ENST00000488576.1
ENST00000472095.1
family with sequence similarity 107, member B
chr11_+_36317830 2.68 ENST00000530639.1
proline rich 5 like
chrX_-_100183894 2.67 ENST00000328526.5
ENST00000372956.2
XK, Kell blood group complex subunit-related, X-linked
chr14_-_35344093 2.61 ENST00000382422.2
bromodomain adjacent to zinc finger domain, 1A
chr14_+_22987424 2.57 ENST00000390511.1
T cell receptor alpha joining 26
chr3_+_152879985 2.56 ENST00000323534.2
RAP2B, member of RAS oncogene family
chr10_-_14614122 2.51 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
family with sequence similarity 107, member B
chr10_-_14614311 2.48 ENST00000479731.1
ENST00000468492.1
family with sequence similarity 107, member B
chr5_-_175964366 2.40 ENST00000274811.4
ring finger protein 44
chr15_+_81293254 2.40 ENST00000267984.2
mesoderm development candidate 1
chr7_+_115850547 2.34 ENST00000358204.4
ENST00000455989.1
ENST00000537767.1
testis derived transcript (3 LIM domains)
chr10_-_14614095 2.29 ENST00000482277.1
ENST00000378462.1
family with sequence similarity 107, member B
chr2_-_100721801 2.24 ENST00000424600.1
ENST00000441400.1
AF4/FMR2 family, member 3
chr5_-_138725560 2.16 ENST00000412103.2
ENST00000457570.2
marginal zone B and B1 cell-specific protein
chr5_-_138725594 2.15 ENST00000302125.8
marginal zone B and B1 cell-specific protein
chr2_-_208031542 2.14 ENST00000423015.1
Kruppel-like factor 7 (ubiquitous)
chr7_+_139528952 2.14 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr6_-_128222103 2.12 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
thymocyte selection associated
chr1_-_157789850 2.11 ENST00000491942.1
ENST00000358292.3
ENST00000368176.3
Fc receptor-like 1
chr19_-_11450249 2.00 ENST00000222120.3
RAB3D, member RAS oncogene family
chr12_-_31477072 1.99 ENST00000454658.2
family with sequence similarity 60, member A
chr14_+_23846210 1.99 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CKLF-like MARVEL transmembrane domain containing 5
chr15_+_41136216 1.92 ENST00000562057.1
ENST00000344051.4
serine peptidase inhibitor, Kunitz type 1
chr14_+_75746781 1.90 ENST00000555347.1
FBJ murine osteosarcoma viral oncogene homolog
chr17_-_7297833 1.87 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3 readthrough (NMD candidate)
chr8_+_29953163 1.86 ENST00000518192.1
leptin receptor overlapping transcript-like 1
chr17_-_7297519 1.86 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3 readthrough (NMD candidate)
chr10_+_71561649 1.83 ENST00000398978.3
ENST00000354547.3
ENST00000357811.3
collagen, type XIII, alpha 1
chr13_-_72441315 1.82 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
dachshund homolog 1 (Drosophila)
chr1_+_100817262 1.78 ENST00000455467.1
cell division cycle 14A
chr12_-_133464151 1.77 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr11_-_94965667 1.76 ENST00000542176.1
ENST00000278499.2
sestrin 3
chr4_-_70626314 1.74 ENST00000510821.1
sulfotransferase family, cytosolic, 1B, member 1
chr10_+_114710211 1.71 ENST00000349937.2
ENST00000369397.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_+_169923504 1.66 ENST00000357546.2
dehydrogenase/reductase (SDR family) member 9
chr18_+_3449821 1.66 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGFB-induced factor homeobox 1
chr7_+_80231466 1.65 ENST00000309881.7
ENST00000534394.1
CD36 molecule (thrombospondin receptor)
chr12_-_49582593 1.64 ENST00000295766.5
tubulin, alpha 1a
chr2_+_169923577 1.59 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr11_-_77184739 1.58 ENST00000524847.1
p21 protein (Cdc42/Rac)-activated kinase 1
chr11_-_87908600 1.58 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38, member RAS oncogene family
chr15_+_41136734 1.57 ENST00000568580.1
serine peptidase inhibitor, Kunitz type 1
chr5_+_66300464 1.57 ENST00000436277.1
microtubule associated serine/threonine kinase family member 4
chr6_-_27440837 1.57 ENST00000211936.6
zinc finger protein 184
chr6_-_27440460 1.56 ENST00000377419.1
zinc finger protein 184
chr12_+_56324933 1.55 ENST00000549629.1
ENST00000555218.1
diacylglycerol kinase, alpha 80kDa
chr7_-_148581251 1.54 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
enhancer of zeste homolog 2 (Drosophila)
chr8_+_29952914 1.54 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
leptin receptor overlapping transcript-like 1
chr18_+_3450161 1.53 ENST00000551402.1
ENST00000577543.1
TGFB-induced factor homeobox 1
chr8_+_32579341 1.52 ENST00000519240.1
ENST00000539990.1
neuregulin 1
chr11_+_65339820 1.51 ENST00000316409.2
ENST00000449319.2
ENST00000530349.1
family with sequence similarity 89, member B
chr14_+_23845995 1.51 ENST00000359320.3
CKLF-like MARVEL transmembrane domain containing 5
chr10_+_71561630 1.51 ENST00000398974.3
ENST00000398971.3
ENST00000398968.3
ENST00000398966.3
ENST00000398964.3
ENST00000398969.3
ENST00000356340.3
ENST00000398972.3
ENST00000398973.3
collagen, type XIII, alpha 1
chr21_+_30672433 1.51 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_+_71562180 1.51 ENST00000517713.1
ENST00000522165.1
ENST00000520133.1
collagen, type XIII, alpha 1
chr2_+_47168630 1.50 ENST00000263737.6
tetratricopeptide repeat domain 7A
chr8_-_130253482 1.48 ENST00000509893.2
long intergenic non-protein coding RNA 977
chr1_+_200993071 1.48 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
chr15_+_41136369 1.46 ENST00000563656.1
serine peptidase inhibitor, Kunitz type 1
chr8_+_32579321 1.45 ENST00000522402.1
neuregulin 1
chr4_-_103266219 1.44 ENST00000394833.2
solute carrier family 39 (zinc transporter), member 8
chrX_-_153599578 1.43 ENST00000360319.4
ENST00000344736.4
filamin A, alpha
chr14_+_23846328 1.42 ENST00000382809.2
CKLF-like MARVEL transmembrane domain containing 5
chr15_-_52043722 1.42 ENST00000454181.2
LysM, putative peptidoglycan-binding, domain containing 2
chr15_+_75074915 1.42 ENST00000567123.1
ENST00000569462.1
c-src tyrosine kinase
chrX_-_19765692 1.42 ENST00000432234.1
SH3-domain kinase binding protein 1
chr15_+_41136263 1.41 ENST00000568823.1
serine peptidase inhibitor, Kunitz type 1
chr5_+_66124590 1.41 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
microtubule associated serine/threonine kinase family member 4
chr12_+_56324756 1.39 ENST00000331886.5
ENST00000555090.1
diacylglycerol kinase, alpha 80kDa
chr7_-_148725544 1.38 ENST00000413966.1
protein disulfide isomerase family A, member 4
chr2_-_100721923 1.37 ENST00000356421.2
AF4/FMR2 family, member 3
chr6_-_89927151 1.36 ENST00000454853.2
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr12_+_56325231 1.35 ENST00000549368.1
diacylglycerol kinase, alpha 80kDa
chr4_+_78078304 1.34 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
cyclin G2
chr7_+_80275953 1.33 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36 molecule (thrombospondin receptor)
chr16_+_53407383 1.31 ENST00000566383.1
RP11-44F14.2
chr1_+_223101757 1.31 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr12_-_133464118 1.30 ENST00000540963.1
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr4_+_26322987 1.30 ENST00000505958.1
recombination signal binding protein for immunoglobulin kappa J region
chr20_+_30555805 1.30 ENST00000562532.2
XK, Kell blood group complex subunit-related family, member 7
chr16_-_89007491 1.28 ENST00000327483.5
ENST00000564416.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr10_+_71561704 1.27 ENST00000520267.1
collagen, type XIII, alpha 1
chr12_+_9066472 1.26 ENST00000538657.1
polyhomeotic homolog 1 (Drosophila)
chr1_+_144339738 1.26 ENST00000538264.1
Protein LOC642441
chr14_+_22928070 1.25 ENST00000390476.1
T cell receptor delta joining 3
chr7_-_148581360 1.25 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
enhancer of zeste homolog 2 (Drosophila)
chr5_-_114515734 1.25 ENST00000514154.1
ENST00000282369.3
tripartite motif containing 36
chr6_-_11779403 1.23 ENST00000414691.3
androgen-dependent TFPI-regulating protein
chr17_+_57233087 1.23 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr7_-_25702669 1.22 ENST00000446840.1
AC003090.1
chr15_+_75074410 1.22 ENST00000439220.2
c-src tyrosine kinase
chr7_-_25702558 1.22 ENST00000423689.2
AC003090.1
chr3_+_141106643 1.21 ENST00000514251.1
zinc finger and BTB domain containing 38
chr12_-_49582837 1.21 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
tubulin, alpha 1a
chr2_+_47168313 1.21 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
tetratricopeptide repeat domain 7A
chr15_+_65134088 1.20 ENST00000323544.4
ENST00000437723.1
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr8_-_33424636 1.18 ENST00000256257.1
ring finger protein 122
chr2_+_17997763 1.17 ENST00000281047.3
mesogenin 1
chr14_+_22982921 1.16 ENST00000390508.1
T cell receptor alpha joining 29
chr4_+_113152978 1.15 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr15_+_90744745 1.14 ENST00000558051.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr7_-_148725733 1.14 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr4_+_113152881 1.12 ENST00000274000.5
adaptor-related protein complex 1 associated regulatory protein
chr6_+_143929307 1.12 ENST00000427704.2
ENST00000305766.6
phosphatase and actin regulator 2
chr4_-_120243545 1.12 ENST00000274024.3
fatty acid binding protein 2, intestinal
chr3_-_47823298 1.12 ENST00000254480.5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr8_+_32579271 1.12 ENST00000518084.1
neuregulin 1
chr11_-_6677018 1.08 ENST00000299441.3
dachsous cadherin-related 1
chr10_+_114710425 1.08 ENST00000352065.5
ENST00000369395.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_+_166808667 1.06 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
pogo transposable element with KRAB domain
chr20_+_55966444 1.06 ENST00000356208.5
ENST00000440234.2
RNA binding motif protein 38
chr13_-_72440901 1.05 ENST00000359684.2
dachshund homolog 1 (Drosophila)
chr7_+_80275752 1.04 ENST00000419819.2
CD36 molecule (thrombospondin receptor)
chr13_+_76334498 1.04 ENST00000534657.1
LIM domain 7
chr11_+_65999265 1.02 ENST00000528935.1
phosphofurin acidic cluster sorting protein 1
chr16_-_4852915 1.02 ENST00000322048.7
rogdi homolog (Drosophila)
chr12_-_49582978 1.02 ENST00000301071.7
tubulin, alpha 1a
chr6_-_166581333 1.02 ENST00000366876.2
T, brachyury homolog (mouse)
chr7_+_80275621 1.02 ENST00000426978.1
ENST00000432207.1
CD36 molecule (thrombospondin receptor)
chr4_-_103266355 1.01 ENST00000424970.2
solute carrier family 39 (zinc transporter), member 8
chrX_-_39956656 0.99 ENST00000397354.3
ENST00000378444.4
BCL6 corepressor
chr10_+_114710516 0.98 ENST00000542695.1
ENST00000346198.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr7_+_80275663 0.98 ENST00000413265.1
CD36 molecule (thrombospondin receptor)
chr8_-_70745575 0.98 ENST00000524945.1
solute carrier organic anion transporter family, member 5A1
chr6_-_33548006 0.98 ENST00000374467.3
BCL2-antagonist/killer 1
chr7_+_110731062 0.97 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
leucine rich repeat neuronal 3
chr2_-_9143786 0.95 ENST00000462696.1
ENST00000305997.3
membrane bound O-acyltransferase domain containing 2
chr1_-_115053781 0.95 ENST00000358465.2
ENST00000369543.2
tripartite motif containing 33
chr17_+_57232690 0.95 ENST00000262293.4
proline rich 11
chr17_-_39222131 0.95 ENST00000394015.2
keratin associated protein 2-4
chr12_+_1738363 0.95 ENST00000397196.2
wingless-type MMTV integration site family, member 5B
chr1_-_32801825 0.93 ENST00000329421.7
MARCKS-like 1
chr1_+_110091189 0.92 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr8_-_17104099 0.92 ENST00000524358.1
CCR4-NOT transcription complex, subunit 7
chr2_-_37551846 0.91 ENST00000443187.1
protein kinase D3
chr1_+_36348790 0.91 ENST00000373204.4
argonaute RISC catalytic component 1
chr6_-_11779174 0.90 ENST00000379413.2
androgen-dependent TFPI-regulating protein
chr6_-_33547975 0.89 ENST00000442998.2
ENST00000360661.5
BCL2-antagonist/killer 1
chr14_-_23451467 0.89 ENST00000555074.1
ENST00000361265.4
RP11-298I3.5
ajuba LIM protein
chr1_+_182808474 0.86 ENST00000367549.3
DEAH (Asp-Glu-Ala-His) box helicase 9
chr22_+_24105394 0.86 ENST00000305199.5
ENST00000382821.3
chromosome 22 open reading frame 15
chrX_+_100645812 0.86 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr22_-_31688431 0.86 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
phosphoinositide-3-kinase interacting protein 1
chr17_+_30813576 0.85 ENST00000313401.3
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr20_+_11008408 0.85 ENST00000378252.1
chromosome 20 open reading frame 187
chr6_+_108881012 0.85 ENST00000343882.6
forkhead box O3
chr5_+_112074029 0.84 ENST00000512211.2
adenomatous polyposis coli
chr7_+_29234028 0.84 ENST00000222792.6
chimerin 2
chr6_-_151712673 0.84 ENST00000325144.4
zinc finger and BTB domain containing 2
chr17_+_59529743 0.82 ENST00000589003.1
ENST00000393853.4
T-box 4
chr12_-_49449107 0.81 ENST00000301067.7
lysine (K)-specific methyltransferase 2D
chr12_+_15475462 0.80 ENST00000543886.1
ENST00000348962.2
protein tyrosine phosphatase, receptor type, O
chr12_-_108154705 0.80 ENST00000547188.1
PR domain containing 4
chr20_-_656437 0.79 ENST00000488788.2
Uncharacterized protein
chr1_+_10459433 0.78 ENST00000465632.1
ENST00000460189.1
phosphogluconate dehydrogenase
chr11_-_65381643 0.77 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr10_+_11206925 0.76 ENST00000354440.2
ENST00000315874.4
ENST00000427450.1
CUGBP, Elav-like family member 2
chr11_-_117747327 0.76 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr20_-_17511962 0.76 ENST00000377873.3
beaded filament structural protein 1, filensin
chr17_-_46690839 0.75 ENST00000498634.2
homeobox B8
chr1_+_166808692 0.75 ENST00000367876.4
pogo transposable element with KRAB domain
chr6_+_12008986 0.75 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chr4_-_123542224 0.75 ENST00000264497.3
interleukin 21
chr13_-_39612176 0.74 ENST00000352251.3
ENST00000350125.3
proline and serine rich 1
chr2_+_32288725 0.72 ENST00000315285.3
spastin
chr22_-_31688381 0.72 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr12_-_49453557 0.72 ENST00000547610.1
lysine (K)-specific methyltransferase 2D
chr2_-_9771075 0.71 ENST00000446619.1
ENST00000238081.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
chr17_+_42081914 0.71 ENST00000293404.3
ENST00000589767.1
N-acetylglutamate synthase
chr2_-_39348137 0.71 ENST00000426016.1
son of sevenless homolog 1 (Drosophila)
chr1_+_32479430 0.70 ENST00000327300.7
ENST00000492989.1
KH domain containing, RNA binding, signal transduction associated 1
chr8_-_29939933 0.69 ENST00000522794.1
transmembrane protein 66
chr18_-_56985873 0.69 ENST00000299721.3
complexin 4
chr7_+_29234101 0.67 ENST00000435288.2
chimerin 2
chr22_+_24105241 0.67 ENST00000402217.3
chromosome 22 open reading frame 15
chr16_+_30406423 0.66 ENST00000524644.1
zinc finger protein 48
chr7_-_106301405 0.66 ENST00000523505.1
coiled-coil domain containing 71-like
chr8_-_29940464 0.65 ENST00000521265.1
ENST00000536273.1
transmembrane protein 66
chr10_+_11207088 0.65 ENST00000608830.1
CUGBP, Elav-like family member 2
chr11_-_117747434 0.65 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD domain containing ion transport regulator 6
chr6_-_107436473 0.65 ENST00000369042.1
BEN domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 10.1 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.9 2.8 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.9 4.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.8 2.3 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.7 4.3 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.6 4.5 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.6 1.9 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.5 4.8 GO:0001661 conditioned taste aversion(GO:0001661)
0.5 6.0 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.5 1.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.5 3.8 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.4 4.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 3.4 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.4 4.1 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.4 2.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.4 1.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.4 1.1 GO:0003192 mitral valve formation(GO:0003192)
0.3 1.6 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 3.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 2.6 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.3 0.9 GO:0021722 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 0.8 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.3 0.8 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 6.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 1.5 GO:0001555 oocyte growth(GO:0001555)
0.2 1.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.2 4.4 GO:0038203 TORC2 signaling(GO:0038203)
0.2 1.6 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.6 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 2.4 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.0 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.2 0.8 GO:0019520 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.2 9.9 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.2 0.6 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 0.5 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.2 0.7 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.2 0.9 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
0.2 1.3 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.7 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 3.0 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 4.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 0.9 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 4.9 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0072679 thymocyte migration(GO:0072679)
0.1 7.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 2.9 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 2.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.6 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.3 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 3.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.1 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.9 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.7 GO:0070307 lens fiber cell development(GO:0070307)
0.1 2.1 GO:0043383 negative T cell selection(GO:0043383)
0.1 0.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 6.3 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 1.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 3.6 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 1.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 1.7 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 2.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.7 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 4.2 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.6 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.5 GO:0060789 hair follicle placode formation(GO:0060789)
0.1 1.3 GO:0060539 diaphragm development(GO:0060539)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 1.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.7 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 1.7 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 1.2 GO:0007379 segment specification(GO:0007379)
0.0 0.3 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.4 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 2.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.4 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:1904637 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 1.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.0 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.6 GO:0050919 negative chemotaxis(GO:0050919)
0.0 4.1 GO:0070268 cornification(GO:0070268)
0.0 1.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 1.0 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 1.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 2.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.8 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.9 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.6 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 1.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.6 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 2.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.5 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.2 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.8 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0043162 viral budding via host ESCRT complex(GO:0039702) ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 6.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
1.0 13.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.9 2.6 GO:0008623 CHRAC(GO:0008623)
0.5 4.8 GO:0035976 AP1 complex(GO:0035976)
0.5 1.4 GO:0075341 host cell PML body(GO:0075341)
0.4 2.9 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.4 1.4 GO:0031523 Myb complex(GO:0031523)
0.3 3.9 GO:0097486 multivesicular body lumen(GO:0097486)
0.3 1.6 GO:0031905 early endosome lumen(GO:0031905)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 7.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 4.4 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 3.2 GO:0045120 pronucleus(GO:0045120)
0.1 1.9 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 2.9 GO:0042588 zymogen granule(GO:0042588)
0.1 1.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.7 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.8 GO:0060091 kinocilium(GO:0060091)
0.1 4.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 4.6 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 2.8 GO:0031105 septin complex(GO:0031105)
0.1 0.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 1.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 2.0 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.6 GO:0071564 npBAF complex(GO:0071564)
0.0 1.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 1.6 GO:0071437 invadopodium(GO:0071437)
0.0 5.9 GO:0016605 PML body(GO:0016605)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 3.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 5.0 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 1.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 1.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 3.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 1.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
1.0 3.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 14.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.5 6.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.5 2.1 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.5 1.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 4.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 2.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 0.9 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.3 0.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 5.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 2.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.2 3.2 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.2 0.8 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.6 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.2 0.5 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.2 4.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 2.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.7 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 4.1 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 2.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.9 GO:0051400 BH domain binding(GO:0051400)
0.1 2.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 4.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 1.0 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 2.0 GO:0031489 myosin V binding(GO:0031489)
0.1 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.1 1.7 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 3.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.6 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 2.9 GO:0019003 GDP binding(GO:0019003)
0.0 2.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.6 GO:0015197 peptide transporter activity(GO:0015197)
0.0 4.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 5.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.9 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0008266 poly-pyrimidine tract binding(GO:0008187) poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 5.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.2 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.3 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 4.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 4.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.4 GO:0001530 lipopolysaccharide binding(GO:0001530)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 4.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 10.6 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 13.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 6.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 2.9 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 3.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 4.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 4.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 3.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 3.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.8 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 3.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 4.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 4.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 6.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 2.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 6.0 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 2.1 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 2.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis