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Illumina Body Map 2

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Results for TEAD3_TEAD1

Z-value: 4.56

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Transcription factors associated with TEAD3_TEAD1

Gene Symbol Gene ID Gene Info
ENSG00000007866.14 TEA domain transcription factor 3
ENSG00000187079.10 TEA domain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEAD1hg19_v2_chr11_+_12766583_127665920.902.1e-12Click!
TEAD3hg19_v2_chr6_-_35464817_354648940.798.3e-08Click!

Activity profile of TEAD3_TEAD1 motif

Sorted Z-values of TEAD3_TEAD1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_132272504 33.59 ENST00000367976.3
connective tissue growth factor
chr1_-_16344500 27.53 ENST00000406363.2
ENST00000411503.1
ENST00000545268.1
ENST00000487046.1
heat shock 27kDa protein family, member 7 (cardiovascular)
chr3_-_119379427 26.48 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
popeye domain containing 2
chr7_+_128470431 25.86 ENST00000325888.8
ENST00000346177.6
filamin C, gamma
chr3_-_119379719 23.38 ENST00000493094.1
popeye domain containing 2
chr14_-_23904861 23.19 ENST00000355349.3
myosin, heavy chain 7, cardiac muscle, beta
chr5_-_138842286 20.40 ENST00000515823.1
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr11_-_111781454 18.02 ENST00000533280.1
crystallin, alpha B
chr4_-_186733363 18.01 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
sorbin and SH3 domain containing 2
chr1_+_86046433 17.38 ENST00000451137.2
cysteine-rich, angiogenic inducer, 61
chr10_-_90712520 16.84 ENST00000224784.6
actin, alpha 2, smooth muscle, aorta
chr14_-_23877474 16.54 ENST00000405093.3
myosin, heavy chain 6, cardiac muscle, alpha
chr17_-_40575535 16.37 ENST00000357037.5
polymerase I and transcript release factor
chr11_+_66824276 14.88 ENST00000308831.2
ras homolog family member D
chr11_+_66824346 14.87 ENST00000532559.1
ras homolog family member D
chr10_+_123872483 14.75 ENST00000369001.1
transforming, acidic coiled-coil containing protein 2
chr10_+_24498060 14.75 ENST00000376454.3
ENST00000376452.3
KIAA1217
chr15_+_96869165 14.26 ENST00000421109.2
nuclear receptor subfamily 2, group F, member 2
chr16_-_122619 14.08 ENST00000262316.6
rhomboid 5 homolog 1 (Drosophila)
chr10_+_24497704 13.96 ENST00000376456.4
ENST00000458595.1
KIAA1217
chr12_-_7245125 13.81 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr3_-_112360116 13.51 ENST00000206423.3
ENST00000439685.2
coiled-coil domain containing 80
chr11_+_66824303 13.49 ENST00000533360.1
ras homolog family member D
chr1_-_201438282 13.26 ENST00000367311.3
ENST00000367309.1
pleckstrin homology-like domain, family A, member 3
chr4_-_187644930 13.06 ENST00000441802.2
FAT atypical cadherin 1
chr4_+_184020398 12.99 ENST00000403733.3
ENST00000378925.3
WW and C2 domain containing 2
chr6_-_35464817 12.96 ENST00000338863.7
TEA domain family member 3
chr6_-_35464727 12.83 ENST00000402886.3
TEA domain family member 3
chr1_-_26394114 12.69 ENST00000374272.3
tripartite motif containing 63, E3 ubiquitin protein ligase
chr12_-_7245152 12.50 ENST00000542220.2
complement component 1, r subcomponent
chr6_+_118869452 12.45 ENST00000357525.5
phospholamban
chr9_+_72658490 12.34 ENST00000377182.4
MAM domain containing 2
chr6_+_30850697 12.03 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr4_-_186732892 11.91 ENST00000451958.1
ENST00000439914.1
ENST00000428330.1
ENST00000429056.1
sorbin and SH3 domain containing 2
chr12_-_7245018 11.88 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr17_-_27949911 11.62 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
coronin 6
chr19_+_45409011 11.58 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
apolipoprotein E
chr12_-_96184533 11.56 ENST00000343702.4
ENST00000344911.4
netrin 4
chr11_-_111782484 11.50 ENST00000533971.1
crystallin, alpha B
chr15_+_63334831 11.33 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
tropomyosin 1 (alpha)
chr12_-_96184913 11.31 ENST00000538383.1
netrin 4
chr2_-_217560248 11.29 ENST00000233813.4
insulin-like growth factor binding protein 5
chr4_-_152149033 11.23 ENST00000514152.1
SH3 domain containing 19
chr11_-_111782696 10.92 ENST00000227251.3
ENST00000526180.1
crystallin, alpha B
chr14_-_89021077 10.82 ENST00000556564.1
protein tyrosine phosphatase, non-receptor type 21
chr8_-_82395461 10.57 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr5_-_38595498 10.50 ENST00000263409.4
leukemia inhibitory factor receptor alpha
chr12_-_7245080 10.48 ENST00000541042.1
ENST00000540242.1
complement component 1, r subcomponent
chr15_+_62853562 10.48 ENST00000561311.1
talin 2
chr1_-_1293904 10.24 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
matrix-remodelling associated 8
chr11_-_111781554 10.06 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chr2_+_27505260 9.99 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr1_+_78354330 9.99 ENST00000440324.1
nexilin (F actin binding protein)
chr16_+_30387141 9.95 ENST00000566955.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_-_111781610 9.94 ENST00000525823.1
crystallin, alpha B
chr3_-_134093275 9.93 ENST00000513145.1
ENST00000422605.2
angiomotin like 2
chr7_+_116165754 9.69 ENST00000405348.1
caveolin 1, caveolae protein, 22kDa
chr1_-_201346761 9.67 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr1_+_78354175 9.55 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
nexilin (F actin binding protein)
chr7_+_116165038 9.53 ENST00000393470.1
caveolin 1, caveolae protein, 22kDa
chr19_+_15218180 9.50 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr10_-_17659234 9.44 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_-_134093395 9.35 ENST00000249883.5
angiomotin like 2
chr1_+_78354243 9.34 ENST00000294624.8
nexilin (F actin binding protein)
chr19_+_34972543 9.13 ENST00000590071.2
Wilms tumor 1 interacting protein
chr1_-_229569834 9.02 ENST00000366684.3
ENST00000366683.2
actin, alpha 1, skeletal muscle
chr1_-_94050668 9.01 ENST00000539242.1
breast cancer anti-estrogen resistance 3
chr1_-_201915590 8.93 ENST00000367288.4
leiomodin 1 (smooth muscle)
chr2_+_228029281 8.89 ENST00000396578.3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr17_-_39677971 8.88 ENST00000393976.2
keratin 15
chr8_+_70378852 8.87 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
sulfatase 1
chrX_-_46187069 8.70 ENST00000446884.1
RP1-30G7.2
chr1_-_11918988 8.69 ENST00000376468.3
natriuretic peptide B
chr7_+_134464376 8.60 ENST00000454108.1
ENST00000361675.2
caldesmon 1
chr4_-_186733119 8.49 ENST00000419063.1
sorbin and SH3 domain containing 2
chr7_+_134464414 8.45 ENST00000361901.2
caldesmon 1
chr1_+_78354297 8.42 ENST00000334785.7
nexilin (F actin binding protein)
chr22_+_26138108 8.39 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
myosin XVIIIB
chr4_+_41614720 8.25 ENST00000509277.1
LIM and calponin homology domains 1
chr11_+_114166536 8.25 ENST00000299964.3
nicotinamide N-methyltransferase
chr1_+_183155373 8.21 ENST00000493293.1
ENST00000264144.4
laminin, gamma 2
chr9_-_13175823 8.17 ENST00000545857.1
multiple PDZ domain protein
chr16_+_28889703 8.11 ENST00000357084.3
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_+_50691437 8.07 ENST00000598205.1
myosin, heavy chain 14, non-muscle
chr1_-_95391315 8.05 ENST00000545882.1
ENST00000415017.1
calponin 3, acidic
chr4_+_41614909 8.01 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr1_-_24438664 7.94 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
myomesin 3
chr16_+_28889801 7.89 ENST00000395503.4
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr18_+_32173276 7.86 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
dystrobrevin, alpha
chr11_+_111782934 7.80 ENST00000304298.3
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr6_-_75915757 7.73 ENST00000322507.8
collagen, type XII, alpha 1
chr16_+_30386098 7.71 ENST00000322861.7
myosin light chain, phosphorylatable, fast skeletal muscle
chr12_-_47219733 7.66 ENST00000547477.1
ENST00000447411.1
ENST00000266579.4
solute carrier family 38, member 4
chr5_+_145316120 7.65 ENST00000359120.4
SH3 domain containing ring finger 2
chr14_-_23451845 7.65 ENST00000262713.2
ajuba LIM protein
chr15_-_99548775 7.56 ENST00000378919.6
pyroglutamyl-peptidase I-like
chr11_-_8832521 7.55 ENST00000530438.1
suppression of tumorigenicity 5
chr16_-_46797149 7.50 ENST00000536476.1
myosin light chain kinase 3
chr3_+_9944303 7.44 ENST00000421412.1
ENST00000295980.3
interleukin 17 receptor E
chr3_-_134093738 7.44 ENST00000506107.1
angiomotin like 2
chr12_-_8815404 7.42 ENST00000359478.2
ENST00000396549.2
microfibrillar associated protein 5
chr1_-_59043166 7.35 ENST00000371225.2
tumor-associated calcium signal transducer 2
chr10_+_69869237 7.29 ENST00000373675.3
myopalladin
chr12_+_27677085 7.28 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PTPRF interacting protein, binding protein 1 (liprin beta 1)
chr12_-_8815215 7.28 ENST00000544889.1
ENST00000543369.1
microfibrillar associated protein 5
chr4_-_186877502 7.15 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
sorbin and SH3 domain containing 2
chr12_-_111358372 7.15 ENST00000548438.1
ENST00000228841.8
myosin, light chain 2, regulatory, cardiac, slow
chr6_+_53883790 6.97 ENST00000509997.1
muscular LMNA-interacting protein
chr22_+_41956767 6.97 ENST00000306149.7
cold shock domain containing C2, RNA binding
chr11_-_47470703 6.91 ENST00000298854.2
receptor-associated protein of the synapse
chrX_+_99899180 6.89 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr4_+_55096489 6.86 ENST00000504461.1
platelet-derived growth factor receptor, alpha polypeptide
chr19_-_54984354 6.85 ENST00000301200.2
CDC42 effector protein (Rho GTPase binding) 5
chr10_+_112404132 6.76 ENST00000369519.3
RNA binding motif protein 20
chr14_+_32964258 6.62 ENST00000556638.1
A kinase (PRKA) anchor protein 6
chr12_+_3068466 6.61 ENST00000358409.2
TEA domain family member 4
chr14_+_63671105 6.57 ENST00000316754.3
ras homolog family member J
chr11_-_76381029 6.57 ENST00000407242.2
ENST00000421973.1
leucine rich repeat containing 32
chr2_-_211179883 6.43 ENST00000352451.3
myosin, light chain 1, alkali; skeletal, fast
chr12_+_3068544 6.42 ENST00000540314.1
ENST00000536826.1
ENST00000359864.2
TEA domain family member 4
chr7_+_134430212 6.30 ENST00000436461.2
caldesmon 1
chr11_+_46299199 6.20 ENST00000529193.1
ENST00000288400.3
cAMP responsive element binding protein 3-like 1
chr2_-_218770168 6.19 ENST00000413554.1
tensin 1
chr20_-_62680984 6.15 ENST00000340356.7
SRY (sex determining region Y)-box 18
chr11_-_119249805 6.15 ENST00000527843.1
ubiquitin specific peptidase 2
chr4_-_186732048 6.14 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
sorbin and SH3 domain containing 2
chr17_+_70117153 6.10 ENST00000245479.2
SRY (sex determining region Y)-box 9
chr11_-_47470682 6.04 ENST00000529341.1
ENST00000352508.3
receptor-associated protein of the synapse
chr17_+_4901199 6.03 ENST00000320785.5
ENST00000574165.1
kinesin family member 1C
chr19_-_49567124 6.02 ENST00000301411.3
neurotrophin 4
chr10_+_50507232 5.99 ENST00000374144.3
chromosome 10 open reading frame 71
chr19_-_46272462 5.98 ENST00000317578.6
SIX homeobox 5
chr12_-_8815299 5.97 ENST00000535336.1
microfibrillar associated protein 5
chr16_+_23194033 5.95 ENST00000300061.2
sodium channel, non-voltage-gated 1, gamma subunit
chr10_-_97175444 5.95 ENST00000486141.2
sorbin and SH3 domain containing 1
chr6_+_53883708 5.93 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
muscular LMNA-interacting protein
chr16_-_46782221 5.85 ENST00000394809.4
myosin light chain kinase 3
chr4_+_169552748 5.85 ENST00000504519.1
ENST00000512127.1
palladin, cytoskeletal associated protein
chr1_+_114522049 5.83 ENST00000369551.1
ENST00000320334.4
olfactomedin-like 3
chr12_-_12419905 5.83 ENST00000535731.1
low density lipoprotein receptor-related protein 6
chr4_+_166300084 5.82 ENST00000402744.4
carboxypeptidase E
chr2_-_216257849 5.77 ENST00000456923.1
fibronectin 1
chr4_+_110834033 5.77 ENST00000509793.1
ENST00000265171.5
epidermal growth factor
chr3_-_149375783 5.75 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WW domain containing transcription regulator 1
chr10_+_123923205 5.70 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chrX_-_10851762 5.69 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr22_+_24577183 5.67 ENST00000358321.3
sushi domain containing 2
chr21_-_40033618 5.63 ENST00000417133.2
ENST00000398910.1
ENST00000442448.1
v-ets avian erythroblastosis virus E26 oncogene homolog
chr5_+_42423872 5.57 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr21_+_17566643 5.54 ENST00000419952.1
ENST00000445461.2
long intergenic non-protein coding RNA 478
chr6_+_19837592 5.53 ENST00000378700.3
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_+_170366203 5.52 ENST00000284669.1
kelch-like family member 41
chr2_+_189157536 5.50 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr13_-_33760216 5.46 ENST00000255486.4
StAR-related lipid transfer (START) domain containing 13
chr10_+_81891416 5.45 ENST00000372270.2
placenta-specific 9
chr9_+_27109440 5.45 ENST00000519080.1
TEK tyrosine kinase, endothelial
chr17_-_73511504 5.43 ENST00000581870.1
CASK interacting protein 2
chr11_-_8832182 5.41 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
suppression of tumorigenicity 5
chr11_-_68780824 5.41 ENST00000441623.1
ENST00000309099.6
MAS-related GPR, member F
chr10_+_50507181 5.40 ENST00000323868.4
chromosome 10 open reading frame 71
chr1_-_161279749 5.37 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
myelin protein zero
chr3_-_52868931 5.31 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr9_-_14308004 5.31 ENST00000493697.1
nuclear factor I/B
chr9_+_109694914 5.30 ENST00000542028.1
zinc finger protein 462
chr4_-_186877806 5.30 ENST00000355634.5
sorbin and SH3 domain containing 2
chr17_-_73511584 5.29 ENST00000321617.3
CASK interacting protein 2
chr2_+_189157498 5.28 ENST00000359135.3
GULP, engulfment adaptor PTB domain containing 1
chr9_+_27109392 5.28 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr1_+_178310581 5.22 ENST00000462775.1
RAS protein activator like 2
chr1_+_66999799 5.20 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SH3-domain GRB2-like (endophilin) interacting protein 1
chr5_-_58882219 5.19 ENST00000505453.1
ENST00000360047.5
phosphodiesterase 4D, cAMP-specific
chr14_+_63671577 5.18 ENST00000555125.1
ras homolog family member J
chr3_+_9944492 5.18 ENST00000383814.3
ENST00000454190.2
ENST00000454992.1
interleukin 17 receptor E
chr15_-_48937982 5.11 ENST00000316623.5
fibrillin 1
chr17_+_73717516 5.06 ENST00000200181.3
ENST00000339591.3
integrin, beta 4
chr11_-_47470591 5.01 ENST00000524487.1
receptor-associated protein of the synapse
chr3_-_66024213 4.97 ENST00000483466.1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chrX_-_33229636 4.96 ENST00000357033.4
dystrophin
chr12_-_8815477 4.92 ENST00000433590.2
microfibrillar associated protein 5
chr11_+_101981169 4.92 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
Yes-associated protein 1
chr15_+_65369082 4.92 ENST00000432196.2
kelch repeat and BTB (POZ) domain containing 13
chr16_+_30907927 4.90 ENST00000279804.2
ENST00000395019.3
cardiotrophin 1
chr6_-_55740352 4.83 ENST00000370830.3
bone morphogenetic protein 5
chr14_-_23446900 4.81 ENST00000556731.1
ajuba LIM protein
chr1_+_62417957 4.72 ENST00000307297.7
ENST00000543708.1
InaD-like (Drosophila)
chr9_+_113431029 4.72 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
muscle, skeletal, receptor tyrosine kinase
chr11_+_7506713 4.71 ENST00000329293.3
ENST00000534244.1
olfactomedin-like 1
chr9_+_102584128 4.69 ENST00000338488.4
ENST00000395097.2
nuclear receptor subfamily 4, group A, member 3
chr3_-_149051444 4.68 ENST00000296059.2
transmembrane 4 L six family member 18
chr1_+_19967014 4.67 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr4_+_111397216 4.66 ENST00000265162.5
glutamyl aminopeptidase (aminopeptidase A)
chr5_-_149516966 4.66 ENST00000517957.1
platelet-derived growth factor receptor, beta polypeptide
chr5_+_150406527 4.62 ENST00000520059.1
glutathione peroxidase 3 (plasma)
chr19_-_49371711 4.62 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr17_+_73717407 4.62 ENST00000579662.1
integrin, beta 4
chr5_-_41213607 4.61 ENST00000337836.5
ENST00000433294.1
complement component 6
chr8_-_81787006 4.56 ENST00000327835.3
zinc finger protein 704
chr15_+_74466744 4.56 ENST00000560862.1
ENST00000395118.1
immunoglobulin superfamily containing leucine-rich repeat
chr3_-_149051194 4.55 ENST00000470080.1
transmembrane 4 L six family member 18
chr4_+_55096010 4.55 ENST00000503856.1
platelet-derived growth factor receptor, alpha polypeptide

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD3_TEAD1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
11.2 33.6 GO:0034059 response to anoxia(GO:0034059)
9.8 39.2 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724)
6.4 19.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
6.0 18.0 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
4.3 25.9 GO:0090131 mesenchyme migration(GO:0090131)
4.1 12.4 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
3.9 11.6 GO:2000646 lipid transport involved in lipid storage(GO:0010877) positive regulation of receptor catabolic process(GO:2000646)
3.8 22.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
3.8 11.3 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
3.6 14.3 GO:0009956 radial pattern formation(GO:0009956)
3.3 13.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.2 9.7 GO:0035261 external genitalia morphogenesis(GO:0035261) canonical Wnt signaling pathway involved in neural crest cell differentiation(GO:0044335)
3.1 6.1 GO:0072197 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
2.7 13.4 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
2.5 17.8 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
2.5 12.7 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
2.5 35.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
2.5 19.9 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.4 60.4 GO:0007021 tubulin complex assembly(GO:0007021)
2.4 12.1 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
2.4 9.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
2.4 61.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
2.2 17.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
2.1 4.2 GO:0007266 Rho protein signal transduction(GO:0007266)
2.1 16.8 GO:0048014 Tie signaling pathway(GO:0048014)
2.0 6.0 GO:0008052 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
2.0 25.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
2.0 5.9 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.9 9.7 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
1.9 5.8 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.9 9.3 GO:0090191 negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191)
1.8 14.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.8 12.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.7 10.3 GO:0061107 seminal vesicle development(GO:0061107)
1.6 13.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
1.6 1.6 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
1.6 6.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
1.6 3.3 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
1.6 4.7 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
1.5 6.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.4 21.1 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
1.4 4.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
1.4 70.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.3 4.0 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.3 4.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
1.3 3.9 GO:0048320 axial mesoderm formation(GO:0048320) negative regulation of lymphangiogenesis(GO:1901491)
1.2 6.2 GO:0048865 stem cell fate commitment(GO:0048865)
1.2 9.8 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
1.2 9.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
1.2 5.8 GO:0030070 insulin processing(GO:0030070)
1.1 12.6 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
1.1 6.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
1.1 14.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
1.0 1.0 GO:1990785 response to water-immersion restraint stress(GO:1990785)
1.0 25.0 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.0 13.0 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
1.0 9.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
1.0 56.1 GO:0035329 hippo signaling(GO:0035329)
1.0 6.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
1.0 6.8 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.9 6.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.9 4.6 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.9 5.5 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.9 8.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.9 4.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.8 2.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.8 14.2 GO:0035878 nail development(GO:0035878)
0.8 8.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.8 5.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.8 5.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.8 8.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.8 6.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.8 1.5 GO:0009644 response to high light intensity(GO:0009644)
0.7 6.7 GO:0072093 metanephric renal vesicle formation(GO:0072093)
0.7 18.8 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.7 1.4 GO:0002035 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051)
0.7 12.0 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.7 11.2 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.7 4.7 GO:0051012 microtubule sliding(GO:0051012)
0.7 4.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.6 3.1 GO:1903412 response to bile acid(GO:1903412)
0.6 0.6 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.6 6.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.6 3.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.6 4.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.6 38.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.6 4.7 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.6 2.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.6 9.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.6 11.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.6 2.8 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.6 3.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.5 1.6 GO:0097106 postsynaptic density organization(GO:0097106)
0.5 10.2 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.5 25.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.5 10.2 GO:0045475 locomotor rhythm(GO:0045475)
0.5 3.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 35.6 GO:0048747 muscle fiber development(GO:0048747)
0.5 5.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.5 11.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.5 7.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.5 1.8 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.5 6.4 GO:0015705 iodide transport(GO:0015705)
0.5 2.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.4 1.8 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.4 3.6 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.4 1.3 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.4 2.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.4 5.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.4 1.3 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 8.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4 8.6 GO:0070314 G1 to G0 transition(GO:0070314)
0.4 1.2 GO:0042245 RNA repair(GO:0042245)
0.4 9.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.4 1.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.4 2.0 GO:0060005 vestibular reflex(GO:0060005)
0.4 8.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.4 1.2 GO:1904888 cranial skeletal system development(GO:1904888)
0.4 52.0 GO:0002027 regulation of heart rate(GO:0002027)
0.4 2.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.4 11.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 3.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.4 2.9 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.4 4.6 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 0.7 GO:0016999 antibiotic metabolic process(GO:0016999)
0.3 54.1 GO:0030449 regulation of complement activation(GO:0030449)
0.3 5.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 6.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 3.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 2.2 GO:0008218 bioluminescence(GO:0008218)
0.3 0.9 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.3 11.6 GO:0071625 vocalization behavior(GO:0071625)
0.3 2.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.3 6.7 GO:0098743 cell aggregation(GO:0098743)
0.3 1.5 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.3 1.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.3 4.1 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.3 7.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.3 1.7 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.3 0.3 GO:2000630 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627) positive regulation of miRNA metabolic process(GO:2000630)
0.3 1.4 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.3 3.6 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.3 3.0 GO:0006528 asparagine metabolic process(GO:0006528)
0.3 3.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 1.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.3 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.3 8.7 GO:0006825 copper ion transport(GO:0006825)
0.2 1.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 8.8 GO:0040023 establishment of nucleus localization(GO:0040023)
0.2 5.8 GO:0003334 keratinocyte development(GO:0003334)
0.2 3.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.7 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.2 3.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2 0.7 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.2 1.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.2 0.6 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 2.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.2 2.8 GO:0060056 mammary gland involution(GO:0060056)
0.2 2.3 GO:0051451 myoblast migration(GO:0051451)
0.2 3.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 4.2 GO:0035994 response to muscle stretch(GO:0035994)
0.2 1.0 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.6 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.2 5.2 GO:0097320 membrane tubulation(GO:0097320)
0.2 6.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.2 37.6 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 3.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 7.1 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 3.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 4.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.2 1.8 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.2 4.2 GO:0051764 actin crosslink formation(GO:0051764)
0.2 2.2 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 2.8 GO:0072189 ureter development(GO:0072189)
0.2 1.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 3.7 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.2 2.3 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 2.4 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.2 1.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 2.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.5 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.2 7.9 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 1.7 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 2.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 7.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 5.0 GO:0030199 collagen fibril organization(GO:0030199)
0.1 13.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 4.5 GO:0055078 sodium ion homeostasis(GO:0055078)
0.1 20.1 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 3.6 GO:0010842 retina layer formation(GO:0010842) retinal ganglion cell axon guidance(GO:0031290)
0.1 3.1 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.9 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.7 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 6.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 18.9 GO:0021987 cerebral cortex development(GO:0021987)
0.1 5.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.1 0.3 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 1.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 19.8 GO:0008016 regulation of heart contraction(GO:0008016)
0.1 26.2 GO:0006936 muscle contraction(GO:0006936)
0.1 1.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 5.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.9 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.3 GO:0071316 cellular response to nicotine(GO:0071316)
0.1 1.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.5 GO:0061046 regulation of branching involved in lung morphogenesis(GO:0061046)
0.1 0.5 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 1.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.7 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.5 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.6 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 1.9 GO:0060325 face morphogenesis(GO:0060325)
0.1 3.0 GO:0030252 growth hormone secretion(GO:0030252)
0.1 4.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 11.1 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.1 0.5 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 1.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.0 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.4 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 2.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.8 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 1.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 14.5 GO:0031032 actomyosin structure organization(GO:0031032)
0.1 1.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.8 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.8 GO:0044351 macropinocytosis(GO:0044351)
0.1 3.3 GO:0010761 fibroblast migration(GO:0010761)
0.1 0.5 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.0 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 1.0 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.6 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 1.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 3.2 GO:1901998 toxin transport(GO:1901998)
0.1 4.8 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 2.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 3.3 GO:0008542 visual learning(GO:0008542)
0.1 0.4 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 6.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 4.2 GO:0051782 negative regulation of cell division(GO:0051782)
0.0 0.6 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.3 GO:0046710 GDP metabolic process(GO:0046710)
0.0 1.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 1.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.4 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 2.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.2 GO:0031638 zymogen activation(GO:0031638)
0.0 3.8 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 1.3 GO:0007035 vacuolar acidification(GO:0007035)
0.0 2.1 GO:0051693 actin filament capping(GO:0051693)
0.0 3.1 GO:0007517 muscle organ development(GO:0007517)
0.0 1.6 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 1.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.8 GO:0008272 sulfate transport(GO:0008272)
0.0 2.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.3 GO:0043586 tongue development(GO:0043586)
0.0 1.8 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.2 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 9.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.6 GO:0017145 stem cell division(GO:0017145)
0.0 0.3 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.8 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 8.8 GO:0006869 lipid transport(GO:0006869)
0.0 1.3 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.9 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.1 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.5 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.1 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.8 GO:1903363 negative regulation of cellular protein catabolic process(GO:1903363)
0.0 2.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.0 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.0 GO:0007343 egg activation(GO:0007343)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 78.2 GO:0097512 cardiac myofibril(GO:0097512)
3.9 11.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
3.0 8.9 GO:0005900 oncostatin-M receptor complex(GO:0005900)
2.8 16.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
2.7 8.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
2.6 7.7 GO:0005595 collagen type XII trimer(GO:0005595)
2.1 8.2 GO:0005607 laminin-2 complex(GO:0005607)
2.0 52.0 GO:0032982 myosin filament(GO:0032982)
1.9 9.7 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.9 5.6 GO:0070195 growth hormone receptor complex(GO:0070195)
1.8 3.6 GO:1990584 cardiac Troponin complex(GO:1990584)
1.4 35.9 GO:0005859 muscle myosin complex(GO:0005859)
1.4 4.2 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
1.2 18.0 GO:0030478 actin cap(GO:0030478)
1.2 4.8 GO:0097182 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.1 28.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
1.1 13.0 GO:0016013 syntrophin complex(GO:0016013)
1.1 18.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.1 18.0 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.0 11.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.0 8.9 GO:0005587 collagen type IV trimer(GO:0005587)
1.0 4.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
1.0 14.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.9 6.0 GO:0005899 insulin receptor complex(GO:0005899)
0.8 2.5 GO:0005588 collagen type V trimer(GO:0005588)
0.8 3.0 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.7 42.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.7 22.9 GO:0005614 interstitial matrix(GO:0005614)
0.7 178.5 GO:0030018 Z disc(GO:0030018)
0.7 14.2 GO:0030056 hemidesmosome(GO:0030056)
0.7 13.1 GO:0032059 bleb(GO:0032059)
0.6 8.8 GO:0002116 semaphorin receptor complex(GO:0002116)
0.6 8.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 22.4 GO:0009925 basal plasma membrane(GO:0009925)
0.5 1.5 GO:1990716 axonemal central apparatus(GO:1990716)
0.5 1.4 GO:0044299 C-fiber(GO:0044299)
0.5 4.6 GO:0005579 membrane attack complex(GO:0005579)
0.4 4.2 GO:0031674 I band(GO:0031674)
0.4 3.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 17.9 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.4 31.6 GO:0005801 cis-Golgi network(GO:0005801)
0.4 29.0 GO:0016235 aggresome(GO:0016235)
0.4 1.1 GO:0000806 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124)
0.4 2.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.3 8.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 0.9 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 3.9 GO:0016600 flotillin complex(GO:0016600)
0.3 6.0 GO:0034706 sodium channel complex(GO:0034706)
0.3 3.0 GO:0005610 laminin-5 complex(GO:0005610)
0.3 4.6 GO:0005869 dynactin complex(GO:0005869)
0.3 52.5 GO:0042383 sarcolemma(GO:0042383)
0.3 30.7 GO:0005604 basement membrane(GO:0005604)
0.3 6.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 7.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 7.9 GO:0031672 A band(GO:0031672)
0.2 2.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 51.4 GO:0072562 blood microparticle(GO:0072562)
0.2 1.0 GO:0071942 XPC complex(GO:0071942)
0.2 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.2 8.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 4.2 GO:0031941 filamentous actin(GO:0031941)
0.2 32.7 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 2.1 GO:0044754 autolysosome(GO:0044754)
0.1 14.7 GO:0031526 brush border membrane(GO:0031526)
0.1 1.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 3.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 84.1 GO:0005667 transcription factor complex(GO:0005667)
0.1 14.4 GO:0005902 microvillus(GO:0005902)
0.1 10.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 2.3 GO:0034709 methylosome(GO:0034709)
0.1 0.6 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 12.5 GO:0005811 lipid particle(GO:0005811)
0.1 10.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 10.1 GO:0005938 cell cortex(GO:0005938)
0.1 5.9 GO:0005903 brush border(GO:0005903)
0.1 40.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 1.5 GO:0032039 integrator complex(GO:0032039)
0.1 10.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.1 7.2 GO:0005871 kinesin complex(GO:0005871)
0.1 37.8 GO:0005769 early endosome(GO:0005769)
0.1 0.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.5 GO:0044305 calyx of Held(GO:0044305)
0.1 11.0 GO:0016605 PML body(GO:0016605)
0.1 19.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 4.2 GO:0005771 multivesicular body(GO:0005771)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 40.1 GO:0005925 focal adhesion(GO:0005925)
0.1 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 3.8 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.4 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 11.4 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 2.1 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 4.4 GO:0005912 adherens junction(GO:0005912)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 6.3 GO:0005795 Golgi stack(GO:0005795)
0.0 2.6 GO:0005581 collagen trimer(GO:0005581)
0.0 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0044853 plasma membrane raft(GO:0044853)
0.0 2.8 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 5.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.0 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 1.2 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
3.2 9.7 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
3.2 19.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
2.9 11.6 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
2.9 11.4 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
2.2 20.2 GO:0043237 laminin-1 binding(GO:0043237)
2.1 8.2 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
2.0 17.6 GO:0017018 myosin phosphatase activity(GO:0017018)
1.8 56.9 GO:0005212 structural constituent of eye lens(GO:0005212)
1.8 12.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
1.7 75.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.6 4.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
1.6 7.9 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.5 63.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.4 12.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
1.4 4.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.4 4.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
1.4 30.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.4 45.9 GO:0005523 tropomyosin binding(GO:0005523)
1.3 13.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.3 12.7 GO:0031432 titin binding(GO:0031432)
1.2 12.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.2 4.7 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor beta-receptor activity(GO:0005019)
1.1 121.4 GO:0008307 structural constituent of muscle(GO:0008307)
1.1 12.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.1 31.7 GO:0031005 filamin binding(GO:0031005)
1.1 16.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.0 7.7 GO:0050682 AF-2 domain binding(GO:0050682)
0.9 3.7 GO:0038132 neuregulin binding(GO:0038132)
0.9 1.8 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.9 6.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.9 29.1 GO:0030506 ankyrin binding(GO:0030506)
0.9 6.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.9 8.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.9 13.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.8 24.6 GO:0043495 protein anchor(GO:0043495)
0.8 4.2 GO:0031013 troponin I binding(GO:0031013)
0.8 6.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.8 3.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.7 8.7 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 7.7 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7 6.7 GO:0016015 morphogen activity(GO:0016015)
0.7 13.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.6 2.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.6 1.8 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.6 7.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.6 1.7 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.5 4.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.5 11.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 13.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.5 4.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.5 2.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.5 9.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.4 13.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 4.4 GO:0032190 acrosin binding(GO:0032190)
0.4 5.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 13.2 GO:0070064 proline-rich region binding(GO:0070064)
0.4 5.9 GO:0070700 BMP receptor binding(GO:0070700)
0.4 9.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.4 1.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 14.6 GO:0001968 fibronectin binding(GO:0001968)
0.4 1.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.4 3.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 6.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.4 14.3 GO:0001972 retinoic acid binding(GO:0001972)
0.4 2.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 5.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 1.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.3 1.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.3 2.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.3 1.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 4.6 GO:0008430 selenium binding(GO:0008430)
0.3 3.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 3.2 GO:0019534 toxin transporter activity(GO:0019534)
0.3 2.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.3 2.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 1.2 GO:0035514 DNA demethylase activity(GO:0035514)
0.3 23.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 1.4 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 10.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.3 3.6 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.3 9.2 GO:0035497 cAMP response element binding(GO:0035497)
0.3 3.0 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.3 1.4 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.3 7.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.3 5.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 4.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 27.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 6.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2 4.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.8 GO:0004969 histamine receptor activity(GO:0004969)
0.2 2.5 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 0.6 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 1.4 GO:0050733 RS domain binding(GO:0050733)
0.2 0.6 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.2 5.1 GO:0031404 chloride ion binding(GO:0031404)
0.2 17.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 5.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 1.6 GO:0031433 telethonin binding(GO:0031433)
0.2 13.2 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.4 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.2 10.2 GO:0030332 cyclin binding(GO:0030332)
0.2 0.8 GO:0010736 serum response element binding(GO:0010736)
0.2 3.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 6.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 1.3 GO:0036122 BMP binding(GO:0036122)
0.2 40.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.2 6.4 GO:0051213 dioxygenase activity(GO:0051213)
0.2 1.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.9 GO:0034711 inhibin binding(GO:0034711)
0.2 8.7 GO:0005504 fatty acid binding(GO:0005504)
0.2 2.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 19.8 GO:0019838 growth factor binding(GO:0019838)
0.2 4.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.2 2.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.2 4.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 28.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 17.0 GO:0032947 protein complex scaffold(GO:0032947)
0.1 4.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 3.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 3.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 3.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 56.7 GO:0003924 GTPase activity(GO:0003924)
0.1 0.9 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.7 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.6 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 7.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 1.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 2.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 13.4 GO:0030165 PDZ domain binding(GO:0030165)
0.1 36.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.6 GO:0005112 Notch binding(GO:0005112)
0.1 3.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.1 GO:0004849 uridine kinase activity(GO:0004849)
0.1 5.8 GO:0016504 peptidase activator activity(GO:0016504)
0.1 39.8 GO:0008017 microtubule binding(GO:0008017)
0.1 5.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 11.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.6 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 1.8 GO:0001054 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.1 0.3 GO:0015563 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1 15.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 1.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 16.0 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 35.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.4 GO:0043532 angiostatin binding(GO:0043532)
0.1 1.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 4.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 2.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.4 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.9 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.8 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.5 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 3.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 1.5 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 4.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 5.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.7 GO:0019825 oxygen binding(GO:0019825)
0.0 0.8 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 4.9 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.9 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 8.3 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 8.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.4 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0035326 enhancer binding(GO:0035326)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 25.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.7 28.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 24.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.5 29.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.5 19.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.3 12.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.3 3.9 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.3 12.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.3 7.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 30.7 PID SHP2 PATHWAY SHP2 signaling
0.3 33.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.3 4.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 25.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 31.0 PID NOTCH PATHWAY Notch signaling pathway
0.2 10.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 21.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 17.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 17.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 10.3 NABA COLLAGENS Genes encoding collagen proteins
0.2 17.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.2 4.7 ST GA12 PATHWAY G alpha 12 Pathway
0.2 5.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 6.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 6.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 13.7 PID AP1 PATHWAY AP-1 transcription factor network
0.1 5.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 6.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.2 PID IL3 PATHWAY IL3-mediated signaling events
0.1 2.4 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 2.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 19.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 5.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 5.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 6.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 5.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 2.4 PID ARF 3PATHWAY Arf1 pathway
0.1 2.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 23.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.9 PID FGF PATHWAY FGF signaling pathway
0.1 1.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 2.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 16.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 5.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 10.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 82.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.1 144.5 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
1.0 36.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.9 33.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.7 19.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.6 25.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.6 3.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.6 25.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.6 16.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.6 14.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.5 15.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 18.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.4 5.8 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.4 3.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.4 16.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.4 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.3 28.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.3 4.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.3 37.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.2 19.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 5.9 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 5.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 6.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 6.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 3.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.2 10.1 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 8.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 4.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 15.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 7.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 4.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 30.5 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 10.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 2.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 0.9 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 6.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 8.4 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.1 2.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 4.0 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 0.3 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 1.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 4.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 5.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 10.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport