Project
Illumina Body Map 2
Navigation
Downloads
Results for TFAP2C
Z-value: 1.42
Motif logo
Transcription factors associated with TFAP2C
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFAP2C | hg19_v2_chr20_+_55205825_55205938 | 0.54 | 1.3e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_54676884 Show fit | 2.41 |
ENST00000376591.4
|
transmembrane channel-like 4 |
|
| chr9_-_115653176 Show fit | 2.05 |
ENST00000374228.4
|
solute carrier family 46, member 2 |
|
| chrX_+_101380642 Show fit | 1.90 |
ENST00000372780.1
ENST00000329035.2 |
transcription elongation factor A (SII)-like 2 |
|
| chr9_-_140064496 Show fit | 1.85 |
ENST00000371542.3
|
leucine rich repeat containing 26 |
|
| chr8_-_11324273 Show fit | 1.83 |
ENST00000284486.4
|
family with sequence similarity 167, member A |
|
| chr4_-_57522673 Show fit | 1.74 |
ENST00000381255.3
ENST00000317745.7 ENST00000555760.2 ENST00000556614.2 |
HOP homeobox |
|
| chr12_-_52914155 Show fit | 1.73 |
ENST00000549420.1
ENST00000551275.1 ENST00000546577.1 |
keratin 5 |
|
| chr1_+_206317450 Show fit | 1.58 |
ENST00000358184.2
ENST00000361052.3 ENST00000360218.2 |
cathepsin E |
|
| chr19_-_54676846 Show fit | 1.57 |
ENST00000301187.4
|
transmembrane channel-like 4 |
|
| chr20_-_18038521 Show fit | 1.57 |
ENST00000278780.6
|
ovo-like zinc finger 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFAP2C
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.5 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
| 0.2 | 5.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.1 | 4.7 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.1 | 3.5 | GO:0042347 | negative regulation of NF-kappaB import into nucleus(GO:0042347) |
| 0.7 | 3.4 | GO:0044027 | hypermethylation of CpG island(GO:0044027) |
| 0.3 | 3.3 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.1 | 3.3 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.3 | 3.1 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 3.1 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 3.0 | GO:0070233 | negative regulation of T cell apoptotic process(GO:0070233) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.9 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 6.1 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 5.2 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
| 0.1 | 4.9 | GO:0042571 | immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 4.3 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 4.0 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.1 | 3.8 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 3.7 | GO:0045095 | keratin filament(GO:0045095) |
| 0.3 | 3.6 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.3 | 3.6 | GO:0034687 | integrin alphaL-beta2 complex(GO:0034687) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.2 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 8.5 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 7.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 7.1 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 6.9 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.0 | 5.0 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.0 | 4.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.3 | 3.6 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 0.1 | 3.5 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.1 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 6.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 5.3 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 5.0 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.5 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.1 | 4.1 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 4.0 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 3.8 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 3.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.1 | 3.6 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 5.9 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.1 | 4.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 4.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 4.5 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 4.0 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 4.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 3.7 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 3.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 3.4 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |