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Illumina Body Map 2
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Results for TFCP2L1
Z-value: 1.75
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Transcription factors associated with TFCP2L1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFCP2L1 | hg19_v2_chr2_-_122042770_122042785 | 0.36 | 4.5e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_55204351 Show fit | 3.69 |
ENST00000201031.2
|
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
|
| chr10_+_102505468 Show fit | 3.62 |
ENST00000361791.3
ENST00000355243.3 ENST00000428433.1 ENST00000370296.2 |
paired box 2 |
|
| chr10_+_102505954 Show fit | 3.54 |
ENST00000556085.1
ENST00000427256.1 |
paired box 2 |
|
| chr17_-_74023474 Show fit | 3.42 |
ENST00000301607.3
|
envoplakin |
|
| chr1_-_153538011 Show fit | 3.39 |
ENST00000368707.4
|
S100 calcium binding protein A2 |
|
| chr17_-_46703826 Show fit | 3.32 |
ENST00000550387.1
ENST00000311177.5 |
homeobox B9 |
|
| chr1_+_27668505 Show fit | 3.21 |
ENST00000318074.5
|
synaptotagmin-like 1 |
|
| chr20_+_44098385 Show fit | 3.17 |
ENST00000217425.5
ENST00000339946.3 |
WAP four-disulfide core domain 2 |
|
| chr17_-_74023291 Show fit | 3.15 |
ENST00000586740.1
|
envoplakin |
|
| chr20_+_44098346 Show fit | 3.14 |
ENST00000372676.3
|
WAP four-disulfide core domain 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFCP2L1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.7 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 2.4 | 7.2 | GO:0035566 | regulation of metanephros size(GO:0035566) |
| 0.1 | 6.9 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 6.2 | GO:0043542 | endothelial cell migration(GO:0043542) |
| 0.2 | 5.8 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 5.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.9 | 5.3 | GO:0030421 | defecation(GO:0030421) |
| 0.0 | 5.1 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.1 | 4.7 | GO:0022011 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.1 | 4.7 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.1 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 5.9 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 5.9 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.1 | 5.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 4.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.1 | 4.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 4.3 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 3.5 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.3 | 3.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 3.2 | GO:0031528 | microvillus membrane(GO:0031528) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.3 | 7.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.4 | 6.6 | GO:0019215 | intermediate filament binding(GO:0019215) |
| 1.1 | 6.3 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 0.6 | 5.7 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.0 | 5.0 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.0 | 4.9 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 4.7 | GO:0003823 | antigen binding(GO:0003823) |
| 0.4 | 4.6 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.3 | 4.3 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 16.9 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 7.9 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 5.8 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 4.7 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 4.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 3.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.1 | 2.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 2.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 1.9 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.8 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.9 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 6.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 5.8 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 5.8 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.1 | 5.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.1 | 5.5 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 3.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 3.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 3.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 2.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |