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Illumina Body Map 2
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Results for TFDP1
Z-value: 1.87
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Transcription factors associated with TFDP1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFDP1 | hg19_v2_chr13_+_114239588_114239752 | 0.16 | 3.9e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFDP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 13.2 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 1.8 | 12.5 | GO:0048619 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 0.9 | 10.4 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.3 | 9.3 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 1.4 | 8.3 | GO:0002572 | pro-T cell differentiation(GO:0002572) |
| 0.7 | 8.2 | GO:0003223 | ventricular compact myocardium morphogenesis(GO:0003223) |
| 0.2 | 8.2 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.2 | 7.6 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.2 | 7.3 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 7.3 | GO:0038096 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 75.9 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.1 | 43.6 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.2 | 29.2 | GO:0016605 | PML body(GO:0016605) |
| 0.4 | 17.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.0 | 16.4 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 14.5 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.4 | 13.8 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.1 | 10.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.1 | 10.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.9 | 8.6 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 28.0 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 25.0 | GO:0003677 | DNA binding(GO:0003677) |
| 0.1 | 22.6 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.1 | 17.0 | GO:0042393 | histone binding(GO:0042393) |
| 0.1 | 15.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.0 | 14.5 | GO:0019787 | ubiquitin-like protein transferase activity(GO:0019787) |
| 0.0 | 13.4 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 11.3 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 10.9 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.1 | 10.8 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 30.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.3 | 14.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.2 | 13.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.2 | 13.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 12.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 11.4 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 11.0 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 0.1 | 10.6 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.1 | 9.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 9.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 20.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 13.5 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.2 | 13.3 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.2 | 12.0 | REACTOME RNA POL I PROMOTER OPENING | Genes involved in RNA Polymerase I Promoter Opening |
| 0.1 | 11.2 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 11.1 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.2 | 10.3 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.2 | 9.6 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.2 | 9.3 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 7.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |