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Illumina Body Map 2
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Results for TGIF1
Z-value: 1.29
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Transcription factors associated with TGIF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TGIF1 | hg19_v2_chr18_+_3450161_3450210 | -0.52 | 2.3e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TGIF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.8 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.2 | 10.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.3 | 6.7 | GO:0047484 | regulation of response to osmotic stress(GO:0047484) |
| 0.3 | 6.4 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.2 | 5.3 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.6 | 4.6 | GO:0038060 | nitric oxide-cGMP-mediated signaling pathway(GO:0038060) |
| 0.3 | 4.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.1 | 4.4 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.4 | 4.3 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.1 | 4.3 | GO:0046710 | GDP metabolic process(GO:0046710) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.0 | GO:0032982 | myosin filament(GO:0032982) |
| 0.2 | 9.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 9.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 6.9 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 5.4 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.4 | 5.3 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 4.5 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.0 | 4.5 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 4.3 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 3.7 | GO:0031430 | M band(GO:0031430) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.1 | 10.1 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.4 | 9.8 | GO:0031432 | titin binding(GO:0031432) |
| 0.2 | 8.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 7.7 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 5.8 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.2 | 5.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.9 | 4.6 | GO:0052839 | inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839) |
| 0.1 | 4.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.5 | 4.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.1 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.1 | 4.2 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 2.8 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 2.1 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 2.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.8 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 1.8 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.3 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 1.2 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.1 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 5.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 5.1 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 4.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.2 | 4.7 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 4.7 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 3.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 2.9 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 2.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 2.3 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |