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Results for TLX1_NFIC
Z-value: 1.96
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Transcription factors associated with TLX1_NFIC
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TLX1
|
ENSG00000107807.8 | T cell leukemia homeobox 1 |
|
NFIC
|
ENSG00000141905.13 | nuclear factor I C |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIC | hg19_v2_chr19_+_3359561_3359681 | 0.42 | 1.8e-02 | Click! |
| TLX1 | hg19_v2_chr10_+_102891048_102891078 | -0.05 | 7.9e-01 | Click! |
Activity profile of TLX1_NFIC motif
Sorted Z-values of TLX1_NFIC motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_-_128788914 | 12.41 |
ENST00000429967.1
ENST00000307484.6 |
APLN
|
apelin |
| chr2_-_217560248 | 7.59 |
ENST00000233813.4
|
IGFBP5
|
insulin-like growth factor binding protein 5 |
| chr8_-_42065075 | 6.95 |
ENST00000429089.2
ENST00000519510.1 ENST00000429710.2 ENST00000524009.1 |
PLAT
|
plasminogen activator, tissue |
| chr7_+_116165038 | 6.91 |
ENST00000393470.1
|
CAV1
|
caveolin 1, caveolae protein, 22kDa |
| chr1_-_153588765 | 6.68 |
ENST00000368701.1
ENST00000344616.2 |
S100A14
|
S100 calcium binding protein A14 |
| chr8_-_42065187 | 6.37 |
ENST00000270189.6
ENST00000352041.3 ENST00000220809.4 |
PLAT
|
plasminogen activator, tissue |
| chr3_-_12200851 | 5.85 |
ENST00000287814.4
|
TIMP4
|
TIMP metallopeptidase inhibitor 4 |
| chr14_+_24867992 | 5.59 |
ENST00000382554.3
|
NYNRIN
|
NYN domain and retroviral integrase containing |
| chrX_+_46937745 | 5.54 |
ENST00000397180.1
ENST00000457380.1 ENST00000352078.4 |
RGN
|
regucalcin |
| chr1_-_16344500 | 5.50 |
ENST00000406363.2
ENST00000411503.1 ENST00000545268.1 ENST00000487046.1 |
HSPB7
|
heat shock 27kDa protein family, member 7 (cardiovascular) |
| chr12_-_56105880 | 5.45 |
ENST00000557257.1
|
ITGA7
|
integrin, alpha 7 |
| chrX_+_2746850 | 5.37 |
ENST00000381163.3
ENST00000338623.5 ENST00000542787.1 |
GYG2
|
glycogenin 2 |
| chr12_-_56106060 | 5.37 |
ENST00000452168.2
|
ITGA7
|
integrin, alpha 7 |
| chr12_+_13349711 | 5.17 |
ENST00000538364.1
ENST00000396301.3 |
EMP1
|
epithelial membrane protein 1 |
| chr12_+_13349650 | 5.15 |
ENST00000256951.5
ENST00000431267.2 ENST00000542474.1 ENST00000544053.1 |
EMP1
|
epithelial membrane protein 1 |
| chr3_-_58613323 | 5.09 |
ENST00000474531.1
ENST00000465970.1 |
FAM107A
|
family with sequence similarity 107, member A |
| chr14_+_85996471 | 5.09 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr11_-_111783919 | 5.05 |
ENST00000531198.1
ENST00000533879.1 |
CRYAB
|
crystallin, alpha B |
| chr6_-_46922659 | 4.97 |
ENST00000265417.7
|
GPR116
|
G protein-coupled receptor 116 |
| chr7_-_16844611 | 4.97 |
ENST00000401412.1
ENST00000419304.2 |
AGR2
|
anterior gradient 2 |
| chr19_+_46806856 | 4.95 |
ENST00000300862.3
|
HIF3A
|
hypoxia inducible factor 3, alpha subunit |
| chr1_-_153538292 | 4.92 |
ENST00000497140.1
ENST00000368708.3 |
S100A2
|
S100 calcium binding protein A2 |
| chr20_-_60942361 | 4.87 |
ENST00000252999.3
|
LAMA5
|
laminin, alpha 5 |
| chrX_+_2746818 | 4.80 |
ENST00000398806.3
|
GYG2
|
glycogenin 2 |
| chr14_+_85996507 | 4.65 |
ENST00000554746.1
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr11_+_74862032 | 4.58 |
ENST00000289575.5
ENST00000341411.4 |
SLCO2B1
|
solute carrier organic anion transporter family, member 2B1 |
| chr11_-_111784005 | 4.57 |
ENST00000527899.1
|
CRYAB
|
crystallin, alpha B |
| chr15_-_68724490 | 4.57 |
ENST00000315757.7
ENST00000423218.2 |
ITGA11
|
integrin, alpha 11 |
| chr11_+_74862140 | 4.49 |
ENST00000525650.1
ENST00000454962.2 |
SLCO2B1
|
solute carrier organic anion transporter family, member 2B1 |
| chr15_+_71228826 | 4.41 |
ENST00000558456.1
ENST00000560158.2 ENST00000558808.1 ENST00000559806.1 ENST00000559069.1 |
LRRC49
|
leucine rich repeat containing 49 |
| chr19_+_45312347 | 4.38 |
ENST00000270233.6
ENST00000591520.1 |
BCAM
|
basal cell adhesion molecule (Lutheran blood group) |
| chr13_+_113622757 | 4.37 |
ENST00000375604.2
|
MCF2L
|
MCF.2 cell line derived transforming sequence-like |
| chr17_-_74533963 | 4.35 |
ENST00000293230.5
|
CYGB
|
cytoglobin |
| chr8_-_22785404 | 4.29 |
ENST00000256404.6
|
PEBP4
|
phosphatidylethanolamine-binding protein 4 |
| chr13_+_113622810 | 4.26 |
ENST00000397030.1
|
MCF2L
|
MCF.2 cell line derived transforming sequence-like |
| chr9_+_102584128 | 4.15 |
ENST00000338488.4
ENST00000395097.2 |
NR4A3
|
nuclear receptor subfamily 4, group A, member 3 |
| chr17_+_77030267 | 4.11 |
ENST00000581774.1
|
C1QTNF1
|
C1q and tumor necrosis factor related protein 1 |
| chr9_+_136399929 | 4.07 |
ENST00000393060.1
|
ADAMTSL2
|
ADAMTS-like 2 |
| chr18_+_21529811 | 4.04 |
ENST00000588004.1
|
LAMA3
|
laminin, alpha 3 |
| chr20_+_58251716 | 3.85 |
ENST00000355648.4
|
PHACTR3
|
phosphatase and actin regulator 3 |
| chr7_+_22766766 | 3.84 |
ENST00000426291.1
ENST00000401651.1 ENST00000258743.5 ENST00000420258.2 ENST00000407492.1 ENST00000401630.3 ENST00000406575.1 |
IL6
|
interleukin 6 (interferon, beta 2) |
| chr15_-_40213080 | 3.79 |
ENST00000561100.1
|
GPR176
|
G protein-coupled receptor 176 |
| chr19_+_45312310 | 3.71 |
ENST00000589651.1
|
BCAM
|
basal cell adhesion molecule (Lutheran blood group) |
| chr11_+_74862100 | 3.69 |
ENST00000532236.1
ENST00000531756.1 |
SLCO2B1
|
solute carrier organic anion transporter family, member 2B1 |
| chr1_-_161168834 | 3.62 |
ENST00000367995.3
ENST00000367996.5 |
ADAMTS4
|
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
| chr2_-_218843623 | 3.60 |
ENST00000413280.1
|
TNS1
|
tensin 1 |
| chr8_-_82395461 | 3.59 |
ENST00000256104.4
|
FABP4
|
fatty acid binding protein 4, adipocyte |
| chr11_-_111781454 | 3.57 |
ENST00000533280.1
|
CRYAB
|
crystallin, alpha B |
| chr7_-_150652924 | 3.55 |
ENST00000330883.4
|
KCNH2
|
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| chr5_+_71475449 | 3.51 |
ENST00000504492.1
|
MAP1B
|
microtubule-associated protein 1B |
| chr8_-_13134246 | 3.44 |
ENST00000503161.2
|
DLC1
|
deleted in liver cancer 1 |
| chr15_+_63682335 | 3.37 |
ENST00000559379.1
ENST00000559821.1 |
RP11-321G12.1
|
RP11-321G12.1 |
| chr10_-_100174900 | 3.33 |
ENST00000370575.4
|
PYROXD2
|
pyridine nucleotide-disulphide oxidoreductase domain 2 |
| chrX_-_102319092 | 3.31 |
ENST00000372728.3
|
BEX1
|
brain expressed, X-linked 1 |
| chr17_-_41910505 | 3.28 |
ENST00000398389.4
|
MPP3
|
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| chr17_+_37894179 | 3.27 |
ENST00000577695.1
ENST00000309156.4 ENST00000309185.3 |
GRB7
|
growth factor receptor-bound protein 7 |
| chr16_-_19896220 | 3.26 |
ENST00000562469.1
ENST00000300571.2 |
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chrX_-_133119476 | 3.23 |
ENST00000543339.1
|
GPC3
|
glypican 3 |
| chr19_+_677885 | 3.22 |
ENST00000591552.2
|
FSTL3
|
follistatin-like 3 (secreted glycoprotein) |
| chr4_-_110723134 | 3.16 |
ENST00000510800.1
ENST00000512148.1 |
CFI
|
complement factor I |
| chr8_+_144295067 | 3.15 |
ENST00000330824.2
|
GPIHBP1
|
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 |
| chr17_+_19314505 | 3.12 |
ENST00000461366.1
|
RNF112
|
ring finger protein 112 |
| chr5_+_92919043 | 3.09 |
ENST00000327111.3
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1 |
| chr6_+_31949801 | 3.09 |
ENST00000428956.2
ENST00000498271.1 |
C4A
|
complement component 4A (Rodgers blood group) |
| chr11_-_30608413 | 3.06 |
ENST00000528686.1
|
MPPED2
|
metallophosphoesterase domain containing 2 |
| chrX_-_133119670 | 3.02 |
ENST00000394299.2
|
GPC3
|
glypican 3 |
| chr3_-_112356944 | 3.00 |
ENST00000461431.1
|
CCDC80
|
coiled-coil domain containing 80 |
| chr15_-_65503801 | 2.95 |
ENST00000261883.4
|
CILP
|
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| chr1_-_41950342 | 2.93 |
ENST00000372587.4
|
EDN2
|
endothelin 2 |
| chr4_-_110723335 | 2.91 |
ENST00000394634.2
|
CFI
|
complement factor I |
| chr17_-_74533734 | 2.83 |
ENST00000589342.1
|
CYGB
|
cytoglobin |
| chr19_-_36247910 | 2.83 |
ENST00000587965.1
ENST00000004982.3 |
HSPB6
|
heat shock protein, alpha-crystallin-related, B6 |
| chr1_+_19967014 | 2.77 |
ENST00000428975.1
|
NBL1
|
neuroblastoma 1, DAN family BMP antagonist |
| chr16_+_226658 | 2.75 |
ENST00000320868.5
ENST00000397797.1 |
HBA1
|
hemoglobin, alpha 1 |
| chrX_-_133119895 | 2.75 |
ENST00000370818.3
|
GPC3
|
glypican 3 |
| chr1_+_185703513 | 2.74 |
ENST00000271588.4
ENST00000367492.2 |
HMCN1
|
hemicentin 1 |
| chr6_+_31982539 | 2.71 |
ENST00000435363.2
ENST00000425700.2 |
C4B
|
complement component 4B (Chido blood group) |
| chr8_+_104384616 | 2.71 |
ENST00000520337.1
|
CTHRC1
|
collagen triple helix repeat containing 1 |
| chr11_-_62457371 | 2.67 |
ENST00000317449.4
|
LRRN4CL
|
LRRN4 C-terminal like |
| chr4_-_110723194 | 2.65 |
ENST00000394635.3
|
CFI
|
complement factor I |
| chr8_-_80680078 | 2.64 |
ENST00000337919.5
ENST00000354724.3 |
HEY1
|
hes-related family bHLH transcription factor with YRPW motif 1 |
| chrX_+_99899180 | 2.64 |
ENST00000373004.3
|
SRPX2
|
sushi-repeat containing protein, X-linked 2 |
| chr6_+_31950150 | 2.64 |
ENST00000537134.1
|
C4A
|
complement component 4A (Rodgers blood group) |
| chr21_+_17792672 | 2.62 |
ENST00000602620.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr5_+_140855495 | 2.55 |
ENST00000308177.3
|
PCDHGC3
|
protocadherin gamma subfamily C, 3 |
| chr19_-_33716750 | 2.53 |
ENST00000253188.4
|
SLC7A10
|
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
| chr1_+_156095951 | 2.52 |
ENST00000448611.2
ENST00000368297.1 |
LMNA
|
lamin A/C |
| chr19_+_11651942 | 2.47 |
ENST00000587087.1
|
CNN1
|
calponin 1, basic, smooth muscle |
| chr14_+_105939276 | 2.44 |
ENST00000483017.3
|
CRIP2
|
cysteine-rich protein 2 |
| chr1_-_153538011 | 2.44 |
ENST00000368707.4
|
S100A2
|
S100 calcium binding protein A2 |
| chr16_+_23765948 | 2.41 |
ENST00000300113.2
|
CHP2
|
calcineurin-like EF-hand protein 2 |
| chr1_+_33231268 | 2.40 |
ENST00000373480.1
|
KIAA1522
|
KIAA1522 |
| chr20_+_56136136 | 2.37 |
ENST00000319441.4
ENST00000543666.1 |
PCK1
|
phosphoenolpyruvate carboxykinase 1 (soluble) |
| chrX_-_114468605 | 2.34 |
ENST00000538422.1
ENST00000317135.8 |
LRCH2
|
leucine-rich repeats and calponin homology (CH) domain containing 2 |
| chr2_+_220325977 | 2.34 |
ENST00000396686.1
ENST00000396689.2 |
SPEG
|
SPEG complex locus |
| chr15_-_40633101 | 2.34 |
ENST00000559313.1
|
C15orf52
|
chromosome 15 open reading frame 52 |
| chr17_+_37894570 | 2.31 |
ENST00000394211.3
|
GRB7
|
growth factor receptor-bound protein 7 |
| chr17_+_38599693 | 2.31 |
ENST00000542955.1
ENST00000269593.4 |
IGFBP4
|
insulin-like growth factor binding protein 4 |
| chr18_+_33877654 | 2.30 |
ENST00000257209.4
ENST00000445677.1 ENST00000590592.1 ENST00000359247.4 |
FHOD3
|
formin homology 2 domain containing 3 |
| chr8_+_91952750 | 2.27 |
ENST00000521366.1
|
NECAB1
|
N-terminal EF-hand calcium binding protein 1 |
| chr1_-_153588334 | 2.27 |
ENST00000476873.1
|
S100A14
|
S100 calcium binding protein A14 |
| chr1_-_151345159 | 2.25 |
ENST00000458566.1
ENST00000447402.3 ENST00000426705.2 ENST00000435071.1 ENST00000368868.5 |
SELENBP1
|
selenium binding protein 1 |
| chr18_-_55470320 | 2.25 |
ENST00000536015.1
|
ATP8B1
|
ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| chr1_+_110453109 | 2.20 |
ENST00000525659.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr16_-_19896150 | 2.20 |
ENST00000570142.1
|
GPRC5B
|
G protein-coupled receptor, family C, group 5, member B |
| chr11_+_27062502 | 2.17 |
ENST00000263182.3
|
BBOX1
|
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| chr1_-_32169920 | 2.15 |
ENST00000373672.3
ENST00000373668.3 |
COL16A1
|
collagen, type XVI, alpha 1 |
| chr12_+_53491220 | 2.15 |
ENST00000548547.1
ENST00000301464.3 |
IGFBP6
|
insulin-like growth factor binding protein 6 |
| chr16_+_222846 | 2.14 |
ENST00000251595.6
ENST00000397806.1 |
HBA2
|
hemoglobin, alpha 2 |
| chr5_-_115872124 | 2.13 |
ENST00000515009.1
|
SEMA6A
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| chrX_+_102631844 | 2.12 |
ENST00000372634.1
ENST00000299872.7 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr9_+_27109133 | 2.11 |
ENST00000519097.1
ENST00000380036.4 |
TEK
|
TEK tyrosine kinase, endothelial |
| chr5_+_150020240 | 2.11 |
ENST00000519664.1
|
SYNPO
|
synaptopodin |
| chr5_-_115872142 | 2.10 |
ENST00000510263.1
|
SEMA6A
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| chr7_+_73242069 | 2.10 |
ENST00000435050.1
|
CLDN4
|
claudin 4 |
| chr19_+_46801639 | 2.07 |
ENST00000244303.6
ENST00000339613.2 ENST00000533145.1 ENST00000472815.1 |
HIF3A
|
hypoxia inducible factor 3, alpha subunit |
| chr20_+_43343476 | 2.03 |
ENST00000372868.2
|
WISP2
|
WNT1 inducible signaling pathway protein 2 |
| chr12_+_119616447 | 2.02 |
ENST00000281938.2
|
HSPB8
|
heat shock 22kDa protein 8 |
| chr7_+_73242490 | 2.00 |
ENST00000431918.1
|
CLDN4
|
claudin 4 |
| chr2_+_220325441 | 1.99 |
ENST00000396688.1
|
SPEG
|
SPEG complex locus |
| chr5_+_150020214 | 1.98 |
ENST00000307662.4
|
SYNPO
|
synaptopodin |
| chr1_+_156096336 | 1.98 |
ENST00000504687.1
ENST00000473598.2 |
LMNA
|
lamin A/C |
| chr9_-_14180778 | 1.92 |
ENST00000380924.1
ENST00000543693.1 |
NFIB
|
nuclear factor I/B |
| chr17_+_7344057 | 1.91 |
ENST00000575398.1
ENST00000575082.1 |
FGF11
|
fibroblast growth factor 11 |
| chr10_+_88718314 | 1.91 |
ENST00000348795.4
|
SNCG
|
synuclein, gamma (breast cancer-specific protein 1) |
| chr2_+_102721023 | 1.90 |
ENST00000409589.1
ENST00000409329.1 |
IL1R1
|
interleukin 1 receptor, type I |
| chr20_+_43343886 | 1.90 |
ENST00000190983.4
|
WISP2
|
WNT1 inducible signaling pathway protein 2 |
| chr6_-_28321971 | 1.89 |
ENST00000396838.2
ENST00000426434.1 ENST00000434036.1 ENST00000439628.1 |
ZSCAN31
|
zinc finger and SCAN domain containing 31 |
| chr1_-_32169761 | 1.89 |
ENST00000271069.6
|
COL16A1
|
collagen, type XVI, alpha 1 |
| chr20_+_33759854 | 1.88 |
ENST00000216968.4
|
PROCR
|
protein C receptor, endothelial |
| chr7_+_128470431 | 1.87 |
ENST00000325888.8
ENST00000346177.6 |
FLNC
|
filamin C, gamma |
| chr15_+_48051920 | 1.85 |
ENST00000559196.1
|
SEMA6D
|
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| chr7_-_7575477 | 1.85 |
ENST00000399429.3
|
COL28A1
|
collagen, type XXVIII, alpha 1 |
| chr9_+_124030338 | 1.83 |
ENST00000449773.1
ENST00000432226.1 ENST00000436847.1 ENST00000394353.2 ENST00000449733.1 ENST00000412819.1 ENST00000341272.2 ENST00000373808.2 |
GSN
|
gelsolin |
| chr11_+_120110863 | 1.81 |
ENST00000543440.2
|
POU2F3
|
POU class 2 homeobox 3 |
| chr20_+_9049682 | 1.79 |
ENST00000334005.3
ENST00000378473.3 |
PLCB4
|
phospholipase C, beta 4 |
| chr21_+_33784670 | 1.77 |
ENST00000300255.2
|
EVA1C
|
eva-1 homolog C (C. elegans) |
| chr21_+_17791648 | 1.77 |
ENST00000602892.1
ENST00000418813.2 ENST00000435697.1 |
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr8_-_27469196 | 1.77 |
ENST00000546343.1
ENST00000560566.1 |
CLU
|
clusterin |
| chr1_+_151512775 | 1.77 |
ENST00000368849.3
ENST00000392712.3 ENST00000353024.3 ENST00000368848.2 ENST00000538902.1 |
TUFT1
|
tuftelin 1 |
| chr4_+_141264597 | 1.76 |
ENST00000338517.4
ENST00000394203.3 ENST00000506322.1 |
SCOC
|
short coiled-coil protein |
| chrX_+_102631248 | 1.75 |
ENST00000361298.4
ENST00000372645.3 ENST00000372635.1 |
NGFRAP1
|
nerve growth factor receptor (TNFRSF16) associated protein 1 |
| chr1_+_65775204 | 1.74 |
ENST00000371069.4
|
DNAJC6
|
DnaJ (Hsp40) homolog, subfamily C, member 6 |
| chr8_-_27468945 | 1.72 |
ENST00000405140.3
|
CLU
|
clusterin |
| chr7_-_16840820 | 1.72 |
ENST00000450569.1
|
AGR2
|
anterior gradient 2 |
| chr19_-_49258606 | 1.72 |
ENST00000310160.3
|
FUT1
|
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| chr21_-_28217721 | 1.71 |
ENST00000284984.3
|
ADAMTS1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| chr6_-_28321827 | 1.68 |
ENST00000444081.1
|
ZSCAN31
|
zinc finger and SCAN domain containing 31 |
| chr8_-_27468842 | 1.68 |
ENST00000523500.1
|
CLU
|
clusterin |
| chr10_+_106034884 | 1.65 |
ENST00000369707.2
ENST00000429569.2 |
GSTO2
|
glutathione S-transferase omega 2 |
| chr6_-_34524049 | 1.65 |
ENST00000374037.3
|
SPDEF
|
SAM pointed domain containing ETS transcription factor |
| chr5_+_39520499 | 1.64 |
ENST00000604954.1
|
CTD-2078B5.2
|
CTD-2078B5.2 |
| chr21_-_35773370 | 1.64 |
ENST00000410005.1
|
AP000322.54
|
chromosome 21 open reading frame 140 |
| chr8_-_13134045 | 1.62 |
ENST00000512044.2
|
DLC1
|
deleted in liver cancer 1 |
| chrX_-_13956737 | 1.61 |
ENST00000454189.2
|
GPM6B
|
glycoprotein M6B |
| chr3_-_50340996 | 1.60 |
ENST00000266031.4
ENST00000395143.2 ENST00000457214.2 ENST00000447605.2 ENST00000418723.1 ENST00000395144.2 |
HYAL1
|
hyaluronoglucosaminidase 1 |
| chr9_-_13279589 | 1.59 |
ENST00000319217.7
|
MPDZ
|
multiple PDZ domain protein |
| chr20_+_34742650 | 1.58 |
ENST00000373945.1
ENST00000338074.2 |
EPB41L1
|
erythrocyte membrane protein band 4.1-like 1 |
| chr20_-_60942326 | 1.56 |
ENST00000370677.3
ENST00000370692.3 |
LAMA5
|
laminin, alpha 5 |
| chr11_+_1244288 | 1.55 |
ENST00000529681.1
ENST00000447027.1 |
MUC5B
|
mucin 5B, oligomeric mucus/gel-forming |
| chr22_+_31518938 | 1.55 |
ENST00000412985.1
ENST00000331075.5 ENST00000412277.2 ENST00000420017.1 ENST00000400294.2 ENST00000405300.1 ENST00000404390.3 |
INPP5J
|
inositol polyphosphate-5-phosphatase J |
| chr9_-_25678856 | 1.55 |
ENST00000358022.3
|
TUSC1
|
tumor suppressor candidate 1 |
| chr2_-_238323007 | 1.55 |
ENST00000295550.4
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr11_+_34663913 | 1.54 |
ENST00000532302.1
|
EHF
|
ets homologous factor |
| chr1_+_33231221 | 1.54 |
ENST00000294521.3
|
KIAA1522
|
KIAA1522 |
| chr9_-_13279563 | 1.53 |
ENST00000541718.1
|
MPDZ
|
multiple PDZ domain protein |
| chr22_+_41763274 | 1.52 |
ENST00000406644.3
|
TEF
|
thyrotrophic embryonic factor |
| chr15_+_84322827 | 1.51 |
ENST00000286744.5
ENST00000567476.1 |
ADAMTSL3
|
ADAMTS-like 3 |
| chr16_-_51185172 | 1.51 |
ENST00000251020.4
|
SALL1
|
spalt-like transcription factor 1 |
| chr6_-_34524093 | 1.50 |
ENST00000544425.1
|
SPDEF
|
SAM pointed domain containing ETS transcription factor |
| chr16_-_86542455 | 1.48 |
ENST00000595886.1
ENST00000597578.1 ENST00000593604.1 |
FENDRR
|
FOXF1 adjacent non-coding developmental regulatory RNA |
| chr21_+_33784957 | 1.48 |
ENST00000401402.3
ENST00000382699.3 |
EVA1C
|
eva-1 homolog C (C. elegans) |
| chr2_-_238322800 | 1.47 |
ENST00000392004.3
ENST00000433762.1 ENST00000347401.3 ENST00000353578.4 ENST00000346358.4 ENST00000392003.2 |
COL6A3
|
collagen, type VI, alpha 3 |
| chr1_-_160040038 | 1.45 |
ENST00000368089.3
|
KCNJ10
|
potassium inwardly-rectifying channel, subfamily J, member 10 |
| chr21_+_17791838 | 1.43 |
ENST00000453910.1
|
LINC00478
|
long intergenic non-protein coding RNA 478 |
| chr22_-_24641027 | 1.43 |
ENST00000398292.3
ENST00000263112.7 ENST00000418439.2 ENST00000424217.1 ENST00000327365.4 |
GGT5
|
gamma-glutamyltransferase 5 |
| chr2_-_238322770 | 1.41 |
ENST00000472056.1
|
COL6A3
|
collagen, type VI, alpha 3 |
| chr8_-_21988558 | 1.40 |
ENST00000312841.8
|
HR
|
hair growth associated |
| chr14_-_50999190 | 1.40 |
ENST00000557390.1
|
MAP4K5
|
mitogen-activated protein kinase kinase kinase kinase 5 |
| chr20_+_43343517 | 1.39 |
ENST00000372865.4
|
WISP2
|
WNT1 inducible signaling pathway protein 2 |
| chr1_-_44497024 | 1.39 |
ENST00000372306.3
ENST00000372310.3 ENST00000475075.2 |
SLC6A9
|
solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| chr14_-_85996332 | 1.38 |
ENST00000380722.1
|
RP11-497E19.1
|
RP11-497E19.1 |
| chr1_+_110453462 | 1.38 |
ENST00000488198.1
|
CSF1
|
colony stimulating factor 1 (macrophage) |
| chr1_-_44497118 | 1.37 |
ENST00000537678.1
ENST00000466926.1 |
SLC6A9
|
solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| chr19_-_42927251 | 1.37 |
ENST00000597001.1
|
LIPE
|
lipase, hormone-sensitive |
| chr22_+_40390930 | 1.37 |
ENST00000333407.6
|
FAM83F
|
family with sequence similarity 83, member F |
| chr15_-_35088340 | 1.37 |
ENST00000290378.4
|
ACTC1
|
actin, alpha, cardiac muscle 1 |
| chr20_-_44519839 | 1.35 |
ENST00000372518.4
|
NEURL2
|
neuralized E3 ubiquitin protein ligase 2 |
| chr8_+_98881268 | 1.35 |
ENST00000254898.5
ENST00000524308.1 ENST00000522025.2 |
MATN2
|
matrilin 2 |
| chr19_-_49864746 | 1.35 |
ENST00000598810.1
|
TEAD2
|
TEA domain family member 2 |
| chr1_-_95392635 | 1.33 |
ENST00000538964.1
ENST00000394202.4 ENST00000370206.4 |
CNN3
|
calponin 3, acidic |
| chr8_-_27468717 | 1.32 |
ENST00000520796.1
ENST00000520491.1 |
CLU
|
clusterin |
| chr17_-_34329084 | 1.32 |
ENST00000354059.4
ENST00000536149.1 |
CCL15
CCL14
|
chemokine (C-C motif) ligand 15 chemokine (C-C motif) ligand 14 |
| chr17_-_39677971 | 1.32 |
ENST00000393976.2
|
KRT15
|
keratin 15 |
| chr8_-_141728760 | 1.30 |
ENST00000430260.2
|
PTK2
|
protein tyrosine kinase 2 |
| chr1_+_32674675 | 1.30 |
ENST00000409358.1
|
DCDC2B
|
doublecortin domain containing 2B |
| chr8_+_24772455 | 1.29 |
ENST00000433454.2
|
NEFM
|
neurofilament, medium polypeptide |
| chr2_-_233877912 | 1.27 |
ENST00000264051.3
|
NGEF
|
neuronal guanine nucleotide exchange factor |
| chr10_+_124320156 | 1.27 |
ENST00000338354.3
ENST00000344338.3 ENST00000330163.4 ENST00000368909.3 ENST00000368955.3 ENST00000368956.2 |
DMBT1
|
deleted in malignant brain tumors 1 |
| chr17_-_10707410 | 1.23 |
ENST00000581851.1
|
LINC00675
|
long intergenic non-protein coding RNA 675 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TLX1_NFIC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.4 | GO:0051466 | positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
| 2.5 | 7.6 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 2.3 | 6.9 | GO:1903609 | negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609) |
| 1.8 | 5.5 | GO:1903625 | negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630) |
| 1.7 | 13.9 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 1.6 | 9.7 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 1.4 | 7.0 | GO:1904141 | mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 1.4 | 4.1 | GO:0032765 | positive regulation of mast cell cytokine production(GO:0032765) |
| 1.3 | 9.0 | GO:0072180 | mesonephric duct morphogenesis(GO:0072180) |
| 1.2 | 3.6 | GO:1902303 | regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303) |
| 1.0 | 7.2 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 1.0 | 2.9 | GO:0003099 | positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 1.0 | 3.8 | GO:1990637 | response to prolactin(GO:1990637) |
| 1.0 | 7.6 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.9 | 2.8 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.9 | 4.5 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.7 | 4.1 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.7 | 2.6 | GO:2000820 | negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820) |
| 0.6 | 1.2 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 0.6 | 2.8 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.5 | 3.2 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 0.5 | 13.2 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.5 | 5.8 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.5 | 4.1 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 0.5 | 1.5 | GO:0001300 | chronological cell aging(GO:0001300) |
| 0.5 | 8.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.5 | 3.2 | GO:0071503 | positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503) |
| 0.4 | 2.2 | GO:0021650 | vestibulocochlear nerve formation(GO:0021650) |
| 0.4 | 13.3 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.4 | 1.3 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.4 | 2.5 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.4 | 1.2 | GO:0060488 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.4 | 1.8 | GO:1903906 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.4 | 9.1 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.3 | 5.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.3 | 10.3 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.3 | 2.0 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.3 | 1.9 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.3 | 1.6 | GO:1900104 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
| 0.3 | 1.9 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 0.3 | 1.1 | GO:0060262 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 0.3 | 0.8 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.3 | 1.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.3 | 0.8 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 0.3 | 2.1 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.3 | 1.0 | GO:1900241 | response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.2 | 1.0 | GO:0018963 | insecticide metabolic process(GO:0017143) phthalate metabolic process(GO:0018963) |
| 0.2 | 1.0 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 0.2 | 1.9 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 3.0 | GO:0042940 | D-amino acid transport(GO:0042940) |
| 0.2 | 5.1 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.2 | 3.2 | GO:0032926 | negative regulation of activin receptor signaling pathway(GO:0032926) |
| 0.2 | 10.6 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.2 | 1.1 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.2 | 0.7 | GO:0097359 | UDP-glucosylation(GO:0097359) |
| 0.2 | 5.6 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.2 | 12.0 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.2 | 2.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.2 | 1.4 | GO:0051935 | amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935) |
| 0.2 | 0.6 | GO:0051758 | homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758) |
| 0.2 | 0.6 | GO:0001579 | medium-chain fatty acid transport(GO:0001579) |
| 0.2 | 3.6 | GO:0071285 | cellular response to lithium ion(GO:0071285) |
| 0.2 | 0.9 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.2 | 0.2 | GO:0035995 | detection of muscle stretch(GO:0035995) |
| 0.2 | 0.7 | GO:0099640 | axo-dendritic protein transport(GO:0099640) |
| 0.2 | 4.2 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.2 | 2.2 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.2 | 0.8 | GO:0003095 | pressure natriuresis(GO:0003095) vitamin E metabolic process(GO:0042360) |
| 0.2 | 0.8 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.2 | 4.6 | GO:0038065 | collagen-activated signaling pathway(GO:0038065) |
| 0.2 | 3.8 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
| 0.2 | 3.5 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.2 | 1.7 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 0.2 | 13.3 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.2 | 0.9 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 0.2 | 1.5 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751) |
| 0.2 | 1.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 1.6 | GO:0051612 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.1 | 2.8 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.1 | 2.0 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.1 | 1.8 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 2.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 1.1 | GO:0098914 | membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) |
| 0.1 | 4.1 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.1 | 1.1 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.4 | GO:2000824 | negative regulation of androgen receptor activity(GO:2000824) |
| 0.1 | 2.5 | GO:1904706 | negative regulation of vascular smooth muscle cell proliferation(GO:1904706) |
| 0.1 | 0.6 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
| 0.1 | 4.0 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 0.3 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.1 | 1.7 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 0.9 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 1.2 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.1 | 0.5 | GO:0015862 | uridine transport(GO:0015862) |
| 0.1 | 0.5 | GO:0072023 | thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233) |
| 0.1 | 0.9 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.1 | 3.7 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 0.3 | GO:0033241 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) negative regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901205) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
| 0.1 | 2.3 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.1 | 1.8 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.1 | 2.4 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.1 | 1.3 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 0.1 | 2.1 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.1 | 1.3 | GO:0048368 | lateral mesoderm development(GO:0048368) |
| 0.1 | 2.8 | GO:0010667 | negative regulation of cardiac muscle cell apoptotic process(GO:0010667) |
| 0.1 | 1.1 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.1 | 0.3 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.1 | 0.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.1 | 1.7 | GO:0070314 | G1 to G0 transition(GO:0070314) |
| 0.1 | 1.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 6.4 | GO:0001755 | neural crest cell migration(GO:0001755) |
| 0.1 | 1.0 | GO:0009407 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 0.1 | 2.6 | GO:0071625 | vocalization behavior(GO:0071625) |
| 0.1 | 3.9 | GO:0046710 | GDP metabolic process(GO:0046710) |
| 0.1 | 0.7 | GO:2000465 | regulation of glycogen (starch) synthase activity(GO:2000465) |
| 0.1 | 1.0 | GO:0046415 | urate metabolic process(GO:0046415) |
| 0.1 | 1.3 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 1.6 | GO:0014912 | negative regulation of smooth muscle cell migration(GO:0014912) |
| 0.1 | 8.9 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.1 | 2.6 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.2 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
| 0.1 | 3.8 | GO:0030818 | negative regulation of cAMP biosynthetic process(GO:0030818) |
| 0.1 | 4.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.1 | 0.3 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.1 | 1.0 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 2.7 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
| 0.1 | 1.9 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.3 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 0.7 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.0 | 0.8 | GO:0060134 | prepulse inhibition(GO:0060134) |
| 0.0 | 1.4 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.0 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.0 | 0.8 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.3 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
| 0.0 | 0.2 | GO:0046271 | phenylpropanoid catabolic process(GO:0046271) |
| 0.0 | 0.8 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.0 | 0.3 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.7 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
| 0.0 | 0.6 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.0 | 0.9 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 0.3 | GO:0035166 | post-embryonic hemopoiesis(GO:0035166) |
| 0.0 | 0.7 | GO:0048569 | post-embryonic organ development(GO:0048569) |
| 0.0 | 1.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.6 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.2 | GO:1902766 | skeletal muscle satellite cell migration(GO:1902766) |
| 0.0 | 5.4 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
| 0.0 | 1.9 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
| 0.0 | 1.2 | GO:0042755 | eating behavior(GO:0042755) |
| 0.0 | 0.5 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.5 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.1 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.0 | 0.6 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 1.5 | GO:0030866 | cortical actin cytoskeleton organization(GO:0030866) |
| 0.0 | 0.5 | GO:1900017 | positive regulation of cytokine production involved in inflammatory response(GO:1900017) |
| 0.0 | 0.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.0 | 0.2 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.0 | 1.2 | GO:0043030 | regulation of macrophage activation(GO:0043030) |
| 0.0 | 0.3 | GO:0050966 | detection of mechanical stimulus involved in sensory perception of pain(GO:0050966) |
| 0.0 | 0.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.0 | 0.1 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.0 | 1.4 | GO:0008347 | glial cell migration(GO:0008347) |
| 0.0 | 3.6 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 1.3 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.0 | 2.3 | GO:0043647 | inositol phosphate metabolic process(GO:0043647) |
| 0.0 | 0.7 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.0 | 4.7 | GO:0043542 | endothelial cell migration(GO:0043542) |
| 0.0 | 3.0 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 2.4 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.1 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
| 0.0 | 0.8 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 4.0 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.2 | GO:2000680 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.0 | 0.5 | GO:0036150 | phosphatidylserine acyl-chain remodeling(GO:0036150) |
| 0.0 | 1.0 | GO:0048747 | muscle fiber development(GO:0048747) |
| 0.0 | 1.2 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 1.2 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.0 | 0.5 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.9 | GO:0010761 | fibroblast migration(GO:0010761) |
| 0.0 | 0.3 | GO:0016578 | histone deubiquitination(GO:0016578) |
| 0.0 | 0.3 | GO:0031954 | positive regulation of protein autophosphorylation(GO:0031954) |
| 0.0 | 0.1 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 0.2 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.8 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.0 | 0.3 | GO:0016242 | negative regulation of macroautophagy(GO:0016242) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.1 | GO:0097444 | spine apparatus(GO:0097444) |
| 1.3 | 6.4 | GO:0043260 | laminin-11 complex(GO:0043260) |
| 1.1 | 4.6 | GO:0034681 | integrin alpha11-beta1 complex(GO:0034681) |
| 1.0 | 7.0 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.8 | 9.7 | GO:0016942 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) |
| 0.7 | 13.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.7 | 3.6 | GO:1902937 | inward rectifier potassium channel complex(GO:1902937) |
| 0.7 | 2.8 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.5 | 1.6 | GO:0036117 | hyaluranon cable(GO:0036117) |
| 0.5 | 1.5 | GO:0072563 | endothelial microparticle(GO:0072563) |
| 0.5 | 8.9 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.4 | 4.5 | GO:0005638 | lamin filament(GO:0005638) |
| 0.4 | 4.0 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.4 | 6.9 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.3 | 4.0 | GO:0005593 | FACIT collagen trimer(GO:0005593) |
| 0.3 | 0.9 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.3 | 1.5 | GO:0070701 | mucus layer(GO:0070701) |
| 0.3 | 4.4 | GO:0005589 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.3 | 1.2 | GO:0060187 | cell pole(GO:0060187) |
| 0.3 | 0.3 | GO:0034665 | integrin alpha1-beta1 complex(GO:0034665) |
| 0.3 | 1.4 | GO:0042643 | actomyosin, actin portion(GO:0042643) |
| 0.3 | 1.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.2 | 0.8 | GO:0036026 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.2 | 11.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.2 | 7.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 0.8 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.2 | 9.7 | GO:0008305 | integrin complex(GO:0008305) |
| 0.1 | 1.8 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 2.0 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 1.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 1.9 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 3.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.7 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 1.6 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.1 | 10.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 0.6 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.1 | 1.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.1 | 1.0 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.1 | 4.1 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.0 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.1 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 33.7 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 2.0 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 1.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 15.6 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 4.3 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 6.9 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 0.4 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.0 | 1.7 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.9 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 0.1 | GO:0042025 | host cell nucleus(GO:0042025) |
| 0.0 | 3.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 5.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 4.4 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.9 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 1.1 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 1.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 2.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 3.6 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 15.5 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 1.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 5.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.3 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.2 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.0 | 2.3 | GO:0044217 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.0 | 18.4 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 1.3 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 0.3 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.5 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.1 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 3.8 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.0 | 0.9 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 0.8 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 2.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.1 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 2.3 | 6.9 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
| 2.3 | 9.0 | GO:0060422 | peptidyl-dipeptidase inhibitor activity(GO:0060422) |
| 2.0 | 10.2 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 1.8 | 7.2 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.9 | 7.0 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.9 | 12.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.8 | 2.4 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.7 | 2.8 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.7 | 4.1 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.7 | 2.6 | GO:0035939 | microsatellite binding(GO:0035939) |
| 0.6 | 4.9 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.6 | 2.9 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.6 | 5.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.5 | 2.2 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.5 | 15.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.5 | 1.4 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.4 | 2.5 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 0.4 | 11.3 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.4 | 3.6 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.4 | 3.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.4 | 9.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.4 | 3.0 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.3 | 1.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.3 | 0.9 | GO:0043849 | Ras palmitoyltransferase activity(GO:0043849) |
| 0.3 | 4.8 | GO:0036122 | BMP binding(GO:0036122) |
| 0.3 | 1.2 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.3 | 1.9 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 0.3 | 12.4 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.2 | 1.8 | GO:0030021 | extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345) |
| 0.2 | 0.7 | GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) |
| 0.2 | 1.0 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.2 | 0.8 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.2 | 2.1 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 6.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.2 | 6.7 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 0.6 | GO:0036328 | VEGF-C-activated receptor activity(GO:0036328) |
| 0.2 | 2.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 1.1 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.2 | 5.8 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 5.5 | GO:0031005 | filamin binding(GO:0031005) |
| 0.2 | 0.7 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.2 | 4.9 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 2.2 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.2 | 1.5 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.2 | 1.0 | GO:0050610 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 0.2 | 6.2 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 0.8 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 0.2 | 0.8 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.2 | 1.4 | GO:0015272 | ATP-activated inward rectifier potassium channel activity(GO:0015272) |
| 0.2 | 2.8 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.1 | 4.1 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 10.3 | GO:0042379 | chemokine receptor binding(GO:0042379) |
| 0.1 | 2.5 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.1 | 0.8 | GO:0050508 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508) |
| 0.1 | 0.6 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.1 | 0.7 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.1 | 1.8 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.1 | 1.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 1.1 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.1 | 1.5 | GO:0052658 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.1 | 10.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 2.3 | GO:0008430 | selenium binding(GO:0008430) |
| 0.1 | 1.6 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 0.1 | 0.9 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.1 | 0.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 0.3 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
| 0.1 | 1.9 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 6.5 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 2.7 | GO:0001848 | complement binding(GO:0001848) |
| 0.1 | 1.7 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 3.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.3 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 12.8 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.1 | 0.8 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.1 | 0.8 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 0.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.1 | 2.9 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 3.4 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 3.9 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.1 | 0.8 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 0.4 | GO:1902444 | riboflavin binding(GO:1902444) |
| 0.1 | 1.9 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 0.6 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.1 | 1.0 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 1.4 | GO:0017022 | myosin binding(GO:0017022) |
| 0.1 | 0.7 | GO:0030247 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.1 | 2.7 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.4 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 1.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.0 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.1 | 0.8 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 8.2 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.3 | GO:0004144 | diacylglycerol O-acyltransferase activity(GO:0004144) |
| 0.0 | 0.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 1.0 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.2 | GO:0035241 | protein-arginine omega-N monomethyltransferase activity(GO:0035241) |
| 0.0 | 0.3 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 7.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 4.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 1.3 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.0 | 3.8 | GO:0030295 | protein kinase activator activity(GO:0030295) |
| 0.0 | 4.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 1.0 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.0 | 0.4 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 0.5 | GO:0019864 | IgG binding(GO:0019864) |
| 0.0 | 0.5 | GO:0001087 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 1.0 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 3.4 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.0 | 5.0 | GO:0052689 | carboxylic ester hydrolase activity(GO:0052689) |
| 0.0 | 2.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.1 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.0 | 0.2 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.5 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 0.0 | 0.5 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.3 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.0 | 0.7 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.4 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 2.2 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 10.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.3 | 14.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.3 | 3.8 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.2 | 10.0 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.2 | 9.6 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.2 | 11.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 7.0 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 5.0 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 6.0 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.1 | 4.0 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.1 | 3.1 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.1 | 26.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 7.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 3.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 6.2 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 2.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 4.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 6.1 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 2.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.9 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 14.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.0 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 11.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.9 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 1.9 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.0 | 1.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 2.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.6 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 1.4 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.0 | 1.5 | PID ER NONGENOMIC PATHWAY | Plasma membrane estrogen receptor signaling |
| 0.0 | 1.6 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 0.7 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.3 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 0.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 1.0 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 1.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.5 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.8 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 13.4 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.4 | 14.4 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.4 | 12.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.3 | 9.9 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.3 | 11.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 9.0 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.2 | 7.2 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.2 | 7.0 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.2 | 5.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.9 | REACTOME PLC BETA MEDIATED EVENTS | Genes involved in PLC beta mediated events |
| 0.1 | 1.6 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 10.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.0 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.1 | 2.8 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 1.3 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.1 | 8.2 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.1 | 3.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 7.8 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 0.8 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 11.0 | REACTOME SIGNALING BY PDGF | Genes involved in Signaling by PDGF |
| 0.1 | 5.9 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.1 | 0.7 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.1 | 2.5 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 6.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.8 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 5.9 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 0.9 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 2.7 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 2.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.5 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.7 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.7 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 1.3 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 2.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.5 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 1.8 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.3 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.4 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |