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Illumina Body Map 2
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Results for UAUUGCU
Z-value: 1.24
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miRNA associated with seed UAUUGCU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-137
|
MIMAT0000429 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_236849754 Show fit | 5.33 |
ENST00000542672.1
ENST00000366578.4 |
actinin, alpha 2 |
|
| chr1_-_33338076 Show fit | 3.59 |
ENST00000496770.1
|
fibronectin type III domain containing 5 |
|
| chr13_+_23755054 Show fit | 3.17 |
ENST00000218867.3
|
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
|
| chr19_-_2721412 Show fit | 2.97 |
ENST00000323469.4
|
DIRAS family, GTP-binding RAS-like 1 |
|
| chr15_+_85359911 Show fit | 2.72 |
ENST00000258888.5
|
alpha-kinase 3 |
|
| chr12_+_125811162 Show fit | 2.64 |
ENST00000299308.3
|
transmembrane protein 132B |
|
| chr11_+_109292846 Show fit | 2.55 |
ENST00000327419.6
|
chromosome 11 open reading frame 87 |
|
| chr1_+_237205476 Show fit | 2.50 |
ENST00000366574.2
|
ryanodine receptor 2 (cardiac) |
|
| chr1_-_217262969 Show fit | 2.39 |
ENST00000361525.3
|
estrogen-related receptor gamma |
|
| chr6_+_17281573 Show fit | 2.39 |
ENST00000379052.5
|
RNA binding motif protein 24 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UAUUGCU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.3 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.3 | 4.1 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.3 | 2.8 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.3 | 2.7 | GO:0015820 | leucine transport(GO:0015820) |
| 0.8 | 2.5 | GO:0003220 | left ventricular cardiac muscle tissue morphogenesis(GO:0003220) |
| 0.2 | 2.5 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 0.1 | 2.3 | GO:0014894 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.4 | 2.2 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.2 | 2.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.7 | 2.1 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.2 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 4.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 4.5 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 4.4 | GO:0099501 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.2 | 4.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 3.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.2 | 3.4 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.3 | 3.2 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 3.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 2.7 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.7 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 1.0 | 4.8 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 4.8 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 4.2 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.0 | 4.2 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 3.8 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 3.7 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.4 | 3.5 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.8 | 3.2 | GO:0048763 | calcium-induced calcium release activity(GO:0048763) |
| 0.0 | 3.1 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 2.3 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 2.0 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 2.0 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.9 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 1.4 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 5.3 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 5.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 4.1 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 3.1 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.1 | 2.7 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 2.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 2.5 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 2.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 2.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |