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Illumina Body Map 2

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Results for UCACAGU

Z-value: 1.25

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miRNA associated with seed UCACAGU

NamemiRBASE accession
hsa-miR-27a-3p
MIMAT0000084
hsa-miR-27b-3p
MIMAT0000419

Activity profile of UCACAGU motif

Sorted Z-values of UCACAGU motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_27183263 3.95 ENST00000222726.3
HOXA5
homeobox A5
chr6_+_41606176 3.22 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MDFI
MyoD family inhibitor
chr1_+_40420802 2.86 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A
major facilitator superfamily domain containing 2A
chr20_-_14318248 2.85 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr8_+_40010989 2.68 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr1_-_47655686 2.66 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr5_-_115910630 2.61 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr17_-_46692287 2.50 ENST00000239144.4
HOXB8
homeobox B8
chr11_+_34642656 2.41 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr6_-_39197226 2.40 ENST00000359534.3
KCNK5
potassium channel, subfamily K, member 5
chr8_+_120220561 2.27 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr15_+_96873921 2.22 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr15_+_81071684 2.20 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199
KIAA1199
chr6_+_50786414 2.17 ENST00000344788.3
ENST00000393655.3
ENST00000263046.4
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr5_+_167718604 2.13 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr9_+_137533615 2.01 ENST00000371817.3
COL5A1
collagen, type V, alpha 1
chr8_+_76452097 1.98 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr15_-_79383102 1.94 ENST00000558480.2
ENST00000419573.3
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr8_+_134203273 1.84 ENST00000250160.6
WISP1
WNT1 inducible signaling pathway protein 1
chr7_-_81399438 1.84 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr15_+_41221536 1.80 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr1_-_95392635 1.77 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
CNN3
calponin 3, acidic
chr19_-_36391434 1.73 ENST00000396901.1
ENST00000585925.1
NFKBID
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
chr4_+_55095264 1.73 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_+_85504075 1.72 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr1_+_199996702 1.71 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr9_+_103790991 1.70 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr16_-_65155833 1.70 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_103981044 1.69 ENST00000388887.2
STAB2
stabilin 2
chr20_+_10199468 1.65 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr9_-_136857403 1.60 ENST00000406606.3
ENST00000371850.3
VAV2
vav 2 guanine nucleotide exchange factor
chr2_+_232260254 1.55 ENST00000287590.5
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr10_-_15762124 1.53 ENST00000378076.3
ITGA8
integrin, alpha 8
chr12_-_88974236 1.50 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr18_+_55102917 1.49 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr2_+_43864387 1.46 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr11_+_58939965 1.44 ENST00000227451.3
DTX4
deltex homolog 4 (Drosophila)
chr3_+_139654018 1.44 ENST00000458420.3
CLSTN2
calsyntenin 2
chr7_-_155604967 1.44 ENST00000297261.2
SHH
sonic hedgehog
chr4_+_115519577 1.44 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr6_-_119399895 1.44 ENST00000338891.7
FAM184A
family with sequence similarity 184, member A
chr4_+_111397216 1.43 ENST00000265162.5
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr22_+_51112800 1.42 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr4_+_20255123 1.42 ENST00000504154.1
ENST00000273739.5
SLIT2
slit homolog 2 (Drosophila)
chr2_-_166651191 1.41 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr7_-_103629963 1.41 ENST00000428762.1
ENST00000343529.5
ENST00000424685.2
RELN
reelin
chr17_-_8534067 1.40 ENST00000360416.3
ENST00000269243.4
MYH10
myosin, heavy chain 10, non-muscle
chr17_+_47572647 1.40 ENST00000172229.3
NGFR
nerve growth factor receptor
chr1_-_200992827 1.40 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr3_-_32022733 1.38 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chrX_-_54384425 1.38 ENST00000375169.3
ENST00000354646.2
WNK3
WNK lysine deficient protein kinase 3
chr11_-_88796803 1.37 ENST00000418177.2
ENST00000455756.2
GRM5
glutamate receptor, metabotropic 5
chr11_+_121322832 1.33 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_-_176981417 1.32 ENST00000514747.1
ENST00000443375.2
ENST00000329540.5
FAM193B
family with sequence similarity 193, member B
chr22_-_37823468 1.32 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr9_+_116917807 1.32 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr5_-_121413974 1.31 ENST00000231004.4
LOX
lysyl oxidase
chr21_+_35445827 1.31 ENST00000608209.1
ENST00000381151.3
SLC5A3
SLC5A3
sodium/myo-inositol cotransporter
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr11_+_130029457 1.29 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr9_+_118916082 1.27 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_+_36421826 1.25 ENST00000273183.3
STAC
SH3 and cysteine rich domain
chr2_-_27718052 1.24 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr2_+_192542850 1.24 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr1_-_68299130 1.24 ENST00000370982.3
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr7_-_108096822 1.24 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr8_-_60031762 1.23 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr20_-_41818373 1.23 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT
protein tyrosine phosphatase, receptor type, T
chr5_+_172068232 1.21 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr5_+_52285144 1.21 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr2_+_46524537 1.19 ENST00000263734.3
EPAS1
endothelial PAS domain protein 1
chr20_+_49348081 1.19 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr5_-_57756087 1.18 ENST00000274289.3
PLK2
polo-like kinase 2
chr1_-_57045228 1.17 ENST00000371250.3
PPAP2B
phosphatidic acid phosphatase type 2B
chr5_+_132149017 1.15 ENST00000378693.2
SOWAHA
sosondowah ankyrin repeat domain family member A
chr6_+_19837592 1.14 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr21_+_33245548 1.13 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr1_-_108507631 1.12 ENST00000527011.1
ENST00000370056.4
VAV3
vav 3 guanine nucleotide exchange factor
chr15_+_80987617 1.12 ENST00000258884.4
ENST00000558464.1
ABHD17C
abhydrolase domain containing 17C
chr12_+_54422142 1.10 ENST00000243108.4
HOXC6
homeobox C6
chr3_+_32859510 1.10 ENST00000383763.5
TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr6_+_127439749 1.09 ENST00000356698.4
RSPO3
R-spondin 3
chr15_-_37390482 1.08 ENST00000559085.1
ENST00000397624.3
MEIS2
Meis homeobox 2
chr9_-_130742792 1.08 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr15_-_63674218 1.07 ENST00000178638.3
CA12
carbonic anhydrase XII
chr18_+_19749386 1.06 ENST00000269216.3
GATA6
GATA binding protein 6
chr10_+_89419370 1.04 ENST00000361175.4
ENST00000456849.1
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr9_-_38069208 1.02 ENST00000377707.3
ENST00000377700.4
SHB
Src homology 2 domain containing adaptor protein B
chr1_+_160370344 1.02 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr2_-_165697920 1.02 ENST00000342193.4
ENST00000375458.2
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr14_+_52118576 1.02 ENST00000395718.2
ENST00000344768.5
FRMD6
FERM domain containing 6
chr13_-_107187462 1.01 ENST00000245323.4
EFNB2
ephrin-B2
chr6_+_136172820 1.00 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chrX_+_17393543 1.00 ENST00000380060.3
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_+_391739 1.00 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr11_+_14665263 1.00 ENST00000282096.4
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr8_-_122653630 0.99 ENST00000303924.4
HAS2
hyaluronan synthase 2
chr6_+_126112001 0.99 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr8_+_80523321 0.97 ENST00000518111.1
STMN2
stathmin-like 2
chr10_-_21786179 0.97 ENST00000377113.5
CASC10
cancer susceptibility candidate 10
chr1_+_955448 0.96 ENST00000379370.2
AGRN
agrin
chr11_-_86666427 0.96 ENST00000531380.1
FZD4
frizzled family receptor 4
chr1_-_48462566 0.96 ENST00000606738.2
TRABD2B
TraB domain containing 2B
chr2_-_235405679 0.96 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr8_-_127570603 0.95 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr17_-_36831156 0.95 ENST00000325814.5
C17orf96
chromosome 17 open reading frame 96
chr11_-_102826434 0.95 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr3_+_122785895 0.95 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr4_+_56815102 0.94 ENST00000257287.4
CEP135
centrosomal protein 135kDa
chr17_+_59529743 0.94 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr6_+_114178512 0.92 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_204329013 0.91 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr19_-_43969796 0.90 ENST00000244333.3
LYPD3
LY6/PLAUR domain containing 3
chr3_-_116164306 0.90 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr5_-_179780312 0.89 ENST00000253778.8
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr14_-_39901618 0.89 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr19_+_45251804 0.88 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr15_+_81293254 0.88 ENST00000267984.2
MESDC1
mesoderm development candidate 1
chr10_+_112257596 0.88 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr7_+_94285637 0.87 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr11_+_369804 0.86 ENST00000329962.6
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr6_-_99873145 0.84 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr1_-_48227290 0.84 ENST00000594280.1
FLJ00388
FLJ00388
chr15_+_33010175 0.84 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr19_+_51815102 0.84 ENST00000270642.8
IGLON5
IgLON family member 5
chr2_-_20212422 0.84 ENST00000421259.2
ENST00000407540.3
MATN3
matrilin 3
chr12_+_79258547 0.83 ENST00000457153.2
SYT1
synaptotagmin I
chr5_+_110559784 0.83 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr16_-_68482440 0.83 ENST00000219334.5
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr6_+_30524663 0.83 ENST00000376560.3
PRR3
proline rich 3
chr19_+_15218180 0.82 ENST00000342784.2
ENST00000597977.1
ENST00000600440.1
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_-_74145273 0.82 ENST00000055682.6
KIAA2022
KIAA2022
chr10_-_90712520 0.81 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_65613217 0.80 ENST00000545314.1
AK4
adenylate kinase 4
chr11_+_101981169 0.78 ENST00000526343.1
ENST00000282441.5
ENST00000537274.1
ENST00000345877.2
YAP1
Yes-associated protein 1
chr10_+_60272814 0.78 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr12_-_54673871 0.77 ENST00000209875.4
CBX5
chromobox homolog 5
chr20_-_62610982 0.77 ENST00000369886.3
ENST00000450107.1
SAMD10
sterile alpha motif domain containing 10
chr3_-_164913777 0.77 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr3_-_134093395 0.76 ENST00000249883.5
AMOTL2
angiomotin like 2
chr12_-_49351303 0.76 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr12_-_77272765 0.76 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chrX_+_78426469 0.76 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr3_+_152879985 0.75 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr8_-_41166953 0.75 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr5_-_160279207 0.75 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr1_+_117452669 0.75 ENST00000393203.2
PTGFRN
prostaglandin F2 receptor inhibitor
chr1_-_206945830 0.75 ENST00000423557.1
IL10
interleukin 10
chr15_+_29131103 0.75 ENST00000558402.1
ENST00000558330.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr12_+_50135588 0.75 ENST00000423828.1
ENST00000550445.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr16_+_1756162 0.74 ENST00000250894.4
ENST00000356010.5
MAPK8IP3
mitogen-activated protein kinase 8 interacting protein 3
chr9_+_114659046 0.74 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr16_+_577697 0.74 ENST00000562370.1
ENST00000568988.1
ENST00000219611.2
CAPN15
calpain 15
chr2_+_204801471 0.74 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr9_+_130830451 0.74 ENST00000373068.2
ENST00000373069.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr19_+_45973120 0.73 ENST00000592811.1
ENST00000586615.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr5_-_38595498 0.73 ENST00000263409.4
LIFR
leukemia inhibitory factor receptor alpha
chr6_+_168841817 0.73 ENST00000356284.2
ENST00000354536.5
SMOC2
SPARC related modular calcium binding 2
chr7_+_20370746 0.73 ENST00000222573.4
ITGB8
integrin, beta 8
chr10_+_8096631 0.73 ENST00000379328.3
GATA3
GATA binding protein 3
chr5_-_59995921 0.73 ENST00000453022.2
ENST00000545085.1
ENST00000265036.5
DEPDC1B
DEP domain containing 1B
chr1_+_228194693 0.73 ENST00000284523.1
ENST00000366753.2
WNT3A
wingless-type MMTV integration site family, member 3A
chr7_+_100210133 0.72 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr3_+_11034403 0.72 ENST00000287766.4
ENST00000425938.1
SLC6A1
solute carrier family 6 (neurotransmitter transporter), member 1
chr15_+_59730348 0.72 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr11_+_120081475 0.71 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr13_+_24734844 0.71 ENST00000382108.3
SPATA13
spermatogenesis associated 13
chr1_+_176432298 0.71 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr12_-_106641728 0.70 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr13_+_33160553 0.70 ENST00000315596.10
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr9_+_132934835 0.70 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr4_-_147442982 0.70 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr17_+_1958388 0.70 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr11_-_67888671 0.69 ENST00000265689.4
CHKA
choline kinase alpha
chr17_+_8924837 0.69 ENST00000173229.2
NTN1
netrin 1
chr17_+_72983674 0.69 ENST00000337231.5
CDR2L
cerebellar degeneration-related protein 2-like
chr5_-_43313574 0.68 ENST00000325110.6
ENST00000433297.2
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_-_75368248 0.68 ENST00000434438.2
ENST00000336926.6
HIP1
huntingtin interacting protein 1
chr5_-_1524015 0.67 ENST00000283415.3
LPCAT1
lysophosphatidylcholine acyltransferase 1
chr17_+_38375574 0.67 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2
WAS/WASL interacting protein family, member 2
chr21_-_39870339 0.67 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG
v-ets avian erythroblastosis virus E26 oncogene homolog
chr12_-_92539614 0.66 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr5_+_74632993 0.66 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr20_+_34700333 0.66 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr16_+_23847339 0.65 ENST00000303531.7
PRKCB
protein kinase C, beta
chr19_+_1286097 0.65 ENST00000215368.2
EFNA2
ephrin-A2
chr21_-_44846999 0.65 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr1_+_82266053 0.65 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr8_-_22550815 0.65 ENST00000317216.2
EGR3
early growth response 3
chr15_+_84322827 0.64 ENST00000286744.5
ENST00000567476.1
ADAMTSL3
ADAMTS-like 3
chrX_+_105066524 0.63 ENST00000243300.9
ENST00000428173.2
NRK
Nik related kinase
chr6_+_142622991 0.63 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr22_-_44258360 0.63 ENST00000330884.4
ENST00000249130.5
SULT4A1
sulfotransferase family 4A, member 1
chr17_+_15848231 0.62 ENST00000304222.2
ADORA2B
adenosine A2b receptor
chr2_-_9143786 0.62 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr1_+_220701456 0.62 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr20_+_3776371 0.61 ENST00000245960.5
CDC25B
cell division cycle 25B
chr12_-_120907459 0.61 ENST00000229390.3
SRSF9
serine/arginine-rich splicing factor 9
chr17_-_80056099 0.61 ENST00000306749.2
FASN
fatty acid synthase
chr7_-_92463210 0.60 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr10_+_104474207 0.60 ENST00000602831.1
ENST00000369893.5
SFXN2
sideroflexin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of UCACAGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0060435 bronchiole development(GO:0060435)
0.7 2.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.9 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.6 2.8 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.6 2.2 GO:0009956 radial pattern formation(GO:0009956)
0.5 3.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.5 1.5 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.5 1.4 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.5 1.4 GO:0071623 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.4 1.3 GO:1902771 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.4 1.7 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.4 2.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.4 1.2 GO:0033341 regulation of collagen binding(GO:0033341)
0.4 0.8 GO:1904956 regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.4 0.7 GO:0100012 regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.4 1.1 GO:0007493 endodermal cell fate determination(GO:0007493)
0.3 1.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.3 1.0 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 2.3 GO:0003344 pericardium morphogenesis(GO:0003344)
0.3 1.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 0.6 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.3 1.7 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.3 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.3 1.1 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.3 0.8 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 0.8 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.3 2.7 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.3 1.0 GO:0000103 sulfate assimilation(GO:0000103)
0.3 0.8 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.7 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 1.0 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.2 1.7 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.2 1.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 1.0 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.2 1.0 GO:1904806 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.2 0.7 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.2 2.2 GO:0097070 ductus arteriosus closure(GO:0097070)
0.2 0.9 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.2 4.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 0.6 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.2 1.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 2.4 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.7 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 1.9 GO:0043129 surfactant homeostasis(GO:0043129)
0.2 1.3 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.3 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.2 1.3 GO:0015798 myo-inositol transport(GO:0015798)
0.2 1.4 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.2 0.7 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.2 1.4 GO:0021592 fourth ventricle development(GO:0021592)
0.2 0.7 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.2 0.3 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 1.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 1.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.2 0.7 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 0.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 2.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.8 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.5 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 0.6 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.2 1.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 2.1 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.7 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.6 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.8 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.4 GO:0021764 amygdala development(GO:0021764)
0.1 2.9 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.1 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 1.1 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.5 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 1.0 GO:0003383 apical constriction(GO:0003383)
0.1 0.1 GO:0045976 negative regulation of mitotic cell cycle, embryonic(GO:0045976)
0.1 1.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0060913 cardiac cell fate determination(GO:0060913)
0.1 0.7 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.3 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 2.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0008355 olfactory learning(GO:0008355)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.3 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1 0.5 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.4 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 2.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.4 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 2.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 1.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 0.4 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.1 1.7 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.4 GO:0006997 nucleus organization(GO:0006997)
0.1 0.9 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.2 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.5 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.4 GO:1901490 regulation of lymphangiogenesis(GO:1901490)
0.1 0.2 GO:0086100 endothelin receptor signaling pathway(GO:0086100)
0.1 2.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.4 GO:0060611 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.1 0.5 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 1.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.7 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.3 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.5 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 0.6 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.3 GO:0035617 stress granule disassembly(GO:0035617)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.8 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.6 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.6 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 1.9 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.6 GO:0097491 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 0.6 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1 0.5 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.7 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.6 GO:0007144 female meiosis I(GO:0007144)
0.0 0.5 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.3 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 1.0 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 1.1 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.3 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.4 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 1.0 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 1.5 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:1904382 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 1.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 1.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 1.2 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.3 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0007619 courtship behavior(GO:0007619) female courtship behavior(GO:0008050)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 1.7 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.4 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.4 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 1.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:1905007 angiogenesis involved in coronary vascular morphogenesis(GO:0060978) positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.2 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.7 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.4 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.6 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 1.0 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.0 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 0.0 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:2000794 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) epithelial cell proliferation involved in lung morphogenesis(GO:0060502) innate vocalization behavior(GO:0098582) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.4 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 1.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.1 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.4 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:1990403 embryonic brain development(GO:1990403)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.3 1.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.3 1.5 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.2 0.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 1.4 GO:0097513 myosin II filament(GO:0097513)
0.2 0.9 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.9 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 1.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 0.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 0.8 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 1.2 GO:0070876 SOSS complex(GO:0070876)
0.2 0.5 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.4 GO:1990032 parallel fiber(GO:1990032)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0009346 citrate lyase complex(GO:0009346)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.8 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 2.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.5 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.6 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 1.0 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.6 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.2 GO:0005605 basal lamina(GO:0005605)
0.0 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 1.4 GO:0030426 growth cone(GO:0030426)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.9 GO:0030315 T-tubule(GO:0030315)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 3.5 GO:0030175 filopodium(GO:0030175)
0.0 4.4 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 2.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 8.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.1 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.6 GO:0044433 cytoplasmic vesicle part(GO:0044433)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.7 GO:0030120 vesicle coat(GO:0030120)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.4 1.7 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.4 1.7 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.4 1.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 1.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.3 1.0 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.3 2.9 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 0.7 GO:0004103 choline kinase activity(GO:0004103)
0.2 0.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.7 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.2 0.6 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.2 0.6 GO:0031177 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 1.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 0.6 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.7 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 0.8 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.2 0.7 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 1.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0005042 netrin receptor activity(GO:0005042)
0.1 1.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 1.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 3.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 4.2 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 2.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 1.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.1 3.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 2.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.5 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.8 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 1.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 1.0 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 2.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.5 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.2 GO:0042301 phosphate ion binding(GO:0042301)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.6 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.0 3.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 2.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 1.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.9 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.9 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.5 GO:0015297 antiporter activity(GO:0015297)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 1.2 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 1.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 12.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0003690 double-stranded DNA binding(GO:0003690)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0031996 thioesterase binding(GO:0031996)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.4 GO:0016758 transferase activity, transferring hexosyl groups(GO:0016758)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 3.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.1 4.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 6.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 4.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.3 0.6 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 1.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 2.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 3.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.7 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 3.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 3.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.2 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 3.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.9 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.4 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 1.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.1 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism