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Illumina Body Map 2

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Results for VSX1

Z-value: 0.97

Motif logo

Transcription factors associated with VSX1

Gene Symbol Gene ID Gene Info
ENSG00000100987.10 visual system homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VSX1hg19_v2_chr20_-_25062767_25062779-0.602.8e-04Click!

Activity profile of VSX1 motif

Sorted Z-values of VSX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_120400960 2.14 ENST00000476082.2
homogentisate 1,2-dioxygenase
chr20_+_56136136 2.08 ENST00000319441.4
ENST00000543666.1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr16_+_68279207 1.66 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
phospholipase A2, group XV
chr16_+_68279256 1.64 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
phospholipase A2, group XV
chr15_+_89631647 1.63 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chrM_+_10758 1.62 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr17_-_66453562 1.58 ENST00000262139.5
ENST00000546360.1
WD repeat domain, phosphoinositide interacting 1
chr6_+_111408698 1.58 ENST00000368851.5
solute carrier family 16 (aromatic amino acid transporter), member 10
chr7_-_148725544 1.56 ENST00000413966.1
protein disulfide isomerase family A, member 4
chr2_-_179672142 1.54 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr3_+_149191723 1.53 ENST00000305354.4
transmembrane 4 L six family member 4
chr6_-_139613269 1.48 ENST00000358430.3
taxilin beta
chr7_-_148725733 1.48 ENST00000286091.4
protein disulfide isomerase family A, member 4
chr11_-_13517565 1.46 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr12_+_16500037 1.40 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr4_-_186570679 1.38 ENST00000451974.1
sorbin and SH3 domain containing 2
chr1_-_169455169 1.37 ENST00000367804.4
ENST00000236137.5
solute carrier family 19 (thiamine transporter), member 2
chr2_+_135596106 1.36 ENST00000356140.5
aminocarboxymuconate semialdehyde decarboxylase
chr9_-_116840728 1.35 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr12_+_16500599 1.34 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr17_-_1532106 1.34 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chrX_-_47509994 1.31 ENST00000343894.4
ELK1, member of ETS oncogene family
chr19_+_19174795 1.30 ENST00000318596.7
solute carrier family 25, member 42
chr15_+_89631381 1.27 ENST00000352732.5
abhydrolase domain containing 2
chr1_+_70876926 1.21 ENST00000370938.3
ENST00000346806.2
cystathionase (cystathionine gamma-lyase)
chr12_-_110011288 1.20 ENST00000540016.1
ENST00000266839.5
methylmalonic aciduria (cobalamin deficiency) cblB type
chr19_-_2256405 1.20 ENST00000300961.6
junctional sarcoplasmic reticulum protein 1
chr3_+_186288454 1.19 ENST00000265028.3
DnaJ (Hsp40) homolog, subfamily B, member 11
chr9_-_35072585 1.19 ENST00000448530.1
valosin containing protein
chrY_+_14958970 1.18 ENST00000453031.1
ubiquitin specific peptidase 9, Y-linked
chr6_+_36164487 1.17 ENST00000357641.6
bromodomain and PHD finger containing, 3
chr18_-_71959159 1.17 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
cytochrome b5 type A (microsomal)
chr1_+_70876891 1.16 ENST00000411986.2
cystathionase (cystathionine gamma-lyase)
chr12_+_16500571 1.14 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr19_-_4717835 1.13 ENST00000599248.1
dipeptidyl-peptidase 9
chr16_-_11036300 1.13 ENST00000331808.4
Dexi homolog (mouse)
chr17_-_7307358 1.11 ENST00000576017.1
ENST00000302422.3
ENST00000535512.1
transmembrane protein 256
TMEM256-PLSCR3 readthrough (NMD candidate)
chr13_-_110438914 1.08 ENST00000375856.3
insulin receptor substrate 2
chr19_-_6737576 1.08 ENST00000601716.1
ENST00000264080.7
G protein-coupled receptor 108
chr12_+_81110684 1.07 ENST00000228644.3
myogenic factor 5
chr1_+_43148059 1.07 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr18_+_3411595 1.05 ENST00000552383.1
TGFB-induced factor homeobox 1
chr2_-_73460334 1.05 ENST00000258083.2
protease-associated domain containing 1
chr16_+_68119440 1.04 ENST00000346183.3
ENST00000329524.4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr1_-_232598163 1.04 ENST00000308942.4
signal-induced proliferation-associated 1 like 2
chr16_+_68119324 1.03 ENST00000349223.5
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr2_-_227050079 1.02 ENST00000423838.1
AC068138.1
chr5_-_95297678 1.00 ENST00000237853.4
elongation factor, RNA polymerase II, 2
chr2_+_234637754 1.00 ENST00000482026.1
ENST00000609767.1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chrX_+_19373700 1.00 ENST00000379804.1
pyruvate dehydrogenase (lipoamide) alpha 1
chr7_-_77427676 0.99 ENST00000257663.3
transmembrane protein 60
chr7_+_74072288 0.98 ENST00000443166.1
general transcription factor IIi
chr10_+_99205959 0.98 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
zinc finger, DHHC-type containing 16
chr4_-_39979576 0.96 ENST00000303538.8
ENST00000503396.1
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr7_+_77428066 0.95 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr19_+_4153598 0.95 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
cAMP responsive element binding protein 3-like 3
chrX_-_21676442 0.94 ENST00000379499.2
kelch-like family member 34
chr1_+_167905894 0.93 ENST00000367843.3
ENST00000432587.2
ENST00000312263.6
DDB1 and CUL4 associated factor 6
chr9_+_34646651 0.93 ENST00000378842.3
galactose-1-phosphate uridylyltransferase
chr10_+_99205894 0.93 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
zinc finger, DHHC-type containing 16
chr6_-_32157947 0.93 ENST00000375050.4
pre-B-cell leukemia homeobox 2
chr14_+_67831576 0.93 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr5_-_95297534 0.93 ENST00000513343.1
ENST00000431061.2
elongation factor, RNA polymerase II, 2
chr4_+_169013666 0.92 ENST00000359299.3
annexin A10
chr16_+_53133070 0.91 ENST00000565832.1
chromodomain helicase DNA binding protein 9
chr6_-_27860956 0.91 ENST00000359611.2
histone cluster 1, H2am
chr22_-_38240316 0.90 ENST00000411961.2
ENST00000434930.1
ankyrin repeat domain 54
chrM_+_4431 0.90 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chrM_+_10464 0.89 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr2_-_192711968 0.88 ENST00000304141.4
serum deprivation response
chr15_+_41523417 0.87 ENST00000560397.1
calcineurin-like EF-hand protein 1
chr6_+_36165133 0.87 ENST00000446974.1
ENST00000454960.1
bromodomain and PHD finger containing, 3
chrX_-_77150911 0.87 ENST00000373336.3
magnesium transporter 1
chr3_-_105587879 0.86 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr6_+_25754927 0.85 ENST00000377905.4
ENST00000439485.2
solute carrier family 17, member 4
chr5_+_151151504 0.85 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_10183651 0.84 ENST00000305883.1
Kruppel-like factor 11
chr12_-_56694083 0.83 ENST00000552688.1
ENST00000548041.1
ENST00000551137.1
ENST00000551968.1
ENST00000542324.2
ENST00000546930.1
ENST00000549221.1
ENST00000550159.1
ENST00000550734.1
citrate synthase
chr19_-_40324767 0.83 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr16_+_68119247 0.82 ENST00000575270.1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_-_104001231 0.82 ENST00000370002.3
paired-like homeodomain 3
chr17_-_47785504 0.81 ENST00000514907.1
ENST00000503334.1
ENST00000508520.1
solute carrier family 35, member B1
chr4_-_119759795 0.81 ENST00000419654.2
SEC24 family member D
chr19_+_13001840 0.80 ENST00000222214.5
ENST00000589039.1
ENST00000591470.1
ENST00000457854.1
ENST00000422947.2
ENST00000588905.1
ENST00000587072.1
glutaryl-CoA dehydrogenase
chr6_+_31783291 0.80 ENST00000375651.5
ENST00000608703.1
ENST00000458062.2
heat shock 70kDa protein 1A
chr17_-_47785265 0.80 ENST00000511763.1
ENST00000515850.1
ENST00000415270.2
ENST00000240333.6
solute carrier family 35, member B1
chr8_+_145159376 0.80 ENST00000322428.5
MAF1 homolog (S. cerevisiae)
chr8_+_145159415 0.80 ENST00000534585.1
MAF1 homolog (S. cerevisiae)
chr17_-_5322786 0.80 ENST00000225696.4
nucleoporin 88kDa
chr11_-_59383617 0.80 ENST00000263847.1
oxysterol binding protein
chr1_+_159750776 0.78 ENST00000368107.1
dual specificity phosphatase 23
chr10_-_5046042 0.78 ENST00000421196.3
ENST00000455190.1
aldo-keto reductase family 1, member C2
chr8_+_92261516 0.78 ENST00000276609.3
ENST00000309536.2
solute carrier family 26 (anion exchanger), member 7
chr12_-_56693758 0.78 ENST00000547298.1
ENST00000551936.1
ENST00000551253.1
ENST00000551473.1
citrate synthase
chrX_+_151999511 0.77 ENST00000370274.3
ENST00000440023.1
ENST00000432467.1
NAD(P) dependent steroid dehydrogenase-like
chr9_+_34646624 0.77 ENST00000450095.2
ENST00000556278.1
galactose-1-phosphate uridylyltransferase
Uncharacterized protein
chr12_-_22063787 0.76 ENST00000544039.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr5_-_49737184 0.75 ENST00000508934.1
ENST00000303221.5
embigin
chr22_+_24309089 0.75 ENST00000215770.5
D-dopachrome tautomerase-like
chr13_-_41593425 0.75 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr15_+_41523335 0.74 ENST00000334660.5
calcineurin-like EF-hand protein 1
chr7_+_77428149 0.74 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr6_+_33172407 0.73 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chrX_-_77150985 0.73 ENST00000358075.6
magnesium transporter 1
chr2_-_70520539 0.71 ENST00000482975.2
ENST00000438261.1
small nuclear ribonucleoprotein polypeptide G
chr3_-_129513259 0.70 ENST00000329333.5
transmembrane and coiled-coil domain family 1
chr5_+_177631497 0.70 ENST00000358344.3
heterogeneous nuclear ribonucleoprotein A/B
chr2_+_86947296 0.70 ENST00000283632.4
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_-_66417107 0.70 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr17_-_5323480 0.69 ENST00000573584.1
nucleoporin 88kDa
chr14_-_73925225 0.68 ENST00000356296.4
ENST00000355058.3
ENST00000359560.3
ENST00000557597.1
ENST00000554394.1
ENST00000555238.1
ENST00000535282.1
ENST00000555987.1
ENST00000555394.1
ENST00000554546.1
numb homolog (Drosophila)
chr16_+_30773610 0.68 ENST00000566811.1
ring finger protein 40, E3 ubiquitin protein ligase
chr2_-_10952832 0.68 ENST00000540494.1
protein disulfide isomerase family A, member 6
chr13_-_50367057 0.68 ENST00000261667.3
karyopherin alpha 3 (importin alpha 4)
chr1_-_221915418 0.67 ENST00000323825.3
ENST00000366899.3
dual specificity phosphatase 10
chr10_+_5005598 0.67 ENST00000442997.1
aldo-keto reductase family 1, member C1
chr5_+_177631523 0.67 ENST00000506339.1
ENST00000355836.5
ENST00000514633.1
ENST00000515193.1
ENST00000506259.1
ENST00000504898.1
heterogeneous nuclear ribonucleoprotein A/B
chr13_-_41240717 0.67 ENST00000379561.5
forkhead box O1
chr22_-_38240412 0.67 ENST00000215941.4
ankyrin repeat domain 54
chr2_-_24270217 0.67 ENST00000295148.4
ENST00000406895.3
chromosome 2 open reading frame 44
chrX_+_70503526 0.67 ENST00000413858.1
ENST00000450092.1
non-POU domain containing, octamer-binding
chr7_-_99699538 0.67 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr19_-_6737241 0.67 ENST00000430424.4
ENST00000597298.1
G protein-coupled receptor 108
chr15_-_53002007 0.67 ENST00000561490.1
family with sequence similarity 214, member A
chrX_+_107334983 0.66 ENST00000457035.1
ENST00000545696.1
autophagy related 4A, cysteine peptidase
chr22_-_24316648 0.66 ENST00000403754.3
ENST00000430101.2
ENST00000398344.4
D-dopachrome tautomerase
chr7_+_99699179 0.66 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr17_+_62223320 0.65 ENST00000580828.1
ENST00000582965.1
small nucleolar RNA, H/ACA box 76
chrX_-_47509887 0.65 ENST00000247161.3
ENST00000592066.1
ENST00000376983.3
ELK1, member of ETS oncogene family
chr19_+_13049413 0.65 ENST00000316448.5
ENST00000588454.1
calreticulin
chr1_+_24286287 0.64 ENST00000334351.7
ENST00000374468.1
proline-rich nuclear receptor coactivator 2
chr16_+_69345243 0.64 ENST00000254950.11
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr1_+_44115814 0.64 ENST00000372396.3
lysine (K)-specific demethylase 4A
chr7_-_137686791 0.64 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
cAMP responsive element binding protein 3-like 2
chr19_+_56652643 0.63 ENST00000586123.1
zinc finger protein 444
chr8_+_97773202 0.63 ENST00000519484.1
carboxypeptidase Q
chr12_-_56694142 0.63 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
citrate synthase
chrX_+_107334895 0.63 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
autophagy related 4A, cysteine peptidase
chr4_+_108911036 0.63 ENST00000505878.1
hydroxyacyl-CoA dehydrogenase
chr5_+_151151471 0.63 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr10_+_74451883 0.62 ENST00000373053.3
ENST00000357157.6
mitochondrial calcium uniporter
chr6_-_26124138 0.62 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr17_+_48172639 0.61 ENST00000503176.1
ENST00000503614.1
pyruvate dehydrogenase kinase, isozyme 2
chr5_+_141303461 0.61 ENST00000508751.1
KIAA0141
chr2_-_61697862 0.61 ENST00000398571.2
ubiquitin specific peptidase 34
chr19_+_10828795 0.61 ENST00000389253.4
ENST00000355667.6
ENST00000408974.4
dynamin 2
chr11_-_3818688 0.61 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
nucleoporin 98kDa
chr19_+_39421556 0.60 ENST00000407800.2
ENST00000402029.3
mitochondrial ribosomal protein S12
chr1_-_167905225 0.60 ENST00000367846.4
mitochondrial pyruvate carrier 2
chr19_+_11485333 0.60 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr11_-_116371347 0.60 ENST00000452629.1
AP001891.1
chr7_+_6048856 0.59 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr2_-_10952922 0.59 ENST00000272227.3
protein disulfide isomerase family A, member 6
chr11_-_66056596 0.59 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr19_-_14228541 0.59 ENST00000590853.1
ENST00000308677.4
protein kinase, cAMP-dependent, catalytic, alpha
chr14_+_24584056 0.59 ENST00000561001.1
DDB1 and CUL4 associated factor 11
chr1_-_154946825 0.58 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC (Src homology 2 domain containing) transforming protein 1
chr8_-_145159083 0.58 ENST00000398712.2
SHANK-associated RH domain interactor
chr11_-_3818932 0.58 ENST00000324932.7
ENST00000359171.4
nucleoporin 98kDa
chr11_-_124981475 0.58 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
transmembrane protein 218
chr7_+_100136811 0.58 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr2_-_96874553 0.58 ENST00000337288.5
ENST00000443962.1
StAR-related lipid transfer (START) domain containing 7
chr1_-_21625486 0.57 ENST00000481130.2
endothelin converting enzyme 1
chr7_-_44613494 0.57 ENST00000431640.1
ENST00000258772.5
DEAD (Asp-Glu-Ala-Asp) box helicase 56
chrX_-_153363125 0.56 ENST00000407218.1
ENST00000453960.2
methyl CpG binding protein 2 (Rett syndrome)
chr8_-_131399110 0.56 ENST00000521426.1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr14_+_24583836 0.56 ENST00000559115.1
ENST00000558215.1
ENST00000557810.1
ENST00000561375.1
ENST00000446197.3
ENST00000559796.1
ENST00000560713.1
ENST00000560901.1
ENST00000559382.1
DDB1 and CUL4 associated factor 11
chr2_+_162087577 0.55 ENST00000439442.1
TRAF family member-associated NFKB activator
chr14_-_73924954 0.55 ENST00000555307.1
ENST00000554818.1
numb homolog (Drosophila)
chr6_+_26124373 0.54 ENST00000377791.2
ENST00000602637.1
histone cluster 1, H2ac
chr19_+_46498704 0.54 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
coiled-coil domain containing 61
chr19_-_14785622 0.54 ENST00000443157.2
egf-like module containing, mucin-like, hormone receptor-like 3
chr17_-_76732928 0.54 ENST00000589768.1
cytohesin 1
chr12_-_21654479 0.54 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RecQ protein-like (DNA helicase Q1-like)
chr5_+_44809027 0.53 ENST00000507110.1
mitochondrial ribosomal protein S30
chr4_-_74853897 0.53 ENST00000296028.3
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr15_-_66816853 0.52 ENST00000568588.1
ribosomal protein L4
chr4_-_34271356 0.52 ENST00000514877.1
RP11-548L20.1
chr12_+_53773944 0.52 ENST00000551969.1
ENST00000327443.4
Sp1 transcription factor
chr14_-_74959994 0.52 ENST00000238633.2
ENST00000434013.2
Niemann-Pick disease, type C2
chr5_+_33441053 0.51 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase
chr7_+_99699280 0.51 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr6_+_32146131 0.50 ENST00000375094.3
ring finger protein 5, E3 ubiquitin protein ligase
chrX_+_46696372 0.50 ENST00000218340.3
retinitis pigmentosa 2 (X-linked recessive)
chr19_-_47616992 0.50 ENST00000253048.5
zinc finger CCCH-type containing 4
chr6_-_18264406 0.50 ENST00000515742.1
DEK oncogene
chr11_+_95523621 0.50 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr4_-_175204765 0.49 ENST00000513696.1
ENST00000503293.1
F-box protein 8
chr19_-_40324255 0.49 ENST00000593685.1
ENST00000600611.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr1_-_152386732 0.49 ENST00000271835.3
cornulin
chr8_+_97773457 0.49 ENST00000521142.1
carboxypeptidase Q
chr6_-_26199471 0.48 ENST00000341023.1
histone cluster 1, H2ad
chr4_+_175204865 0.48 ENST00000505124.1
centrosomal protein 44kDa
chr19_-_46195029 0.48 ENST00000588599.1
ENST00000585392.1
ENST00000590212.1
ENST00000587367.1
ENST00000391932.3
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr17_+_1733251 0.48 ENST00000570451.1
replication protein A1, 70kDa
chr3_-_186288097 0.48 ENST00000446782.1
TBCC domain containing 1
chr11_-_66056478 0.48 ENST00000431556.2
ENST00000528575.1
Yip1 interacting factor homolog A (S. cerevisiae)
chr20_+_3052264 0.47 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr3_-_148939835 0.47 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr17_-_47841485 0.47 ENST00000506156.1
ENST00000240364.2
family with sequence similarity 117, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.8 3.3 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.6 2.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.6 1.7 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.5 1.6 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.5 2.0 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.5 1.5 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.4 1.3 GO:0015880 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.4 1.6 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.4 1.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.3 1.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.3 1.0 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.3 1.2 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.3 1.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.3 1.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.3 1.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 1.4 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 2.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.2 0.9 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.2 1.3 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.2 1.5 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 0.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 1.6 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.2 1.0 GO:0070980 biphenyl catabolic process(GO:0070980)
0.2 0.6 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.2 1.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.6 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 1.3 GO:0051697 protein delipidation(GO:0051697)
0.2 0.7 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.2 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 0.8 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.2 1.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 0.5 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.2 0.5 GO:0009405 pathogenesis(GO:0009405)
0.1 1.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.1 0.7 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 3.7 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.5 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.5 GO:0050993 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.1 1.3 GO:0042167 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 1.6 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.7 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.6 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.9 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.3 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.4 GO:0061743 motor learning(GO:0061743)
0.1 1.6 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.1 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.3 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 1.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.6 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.6 GO:1903525 regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 3.5 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.4 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.3 GO:1903691 negative regulation of muscle atrophy(GO:0014736) positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 1.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 0.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.8 GO:0006568 tryptophan metabolic process(GO:0006568)
0.1 2.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.2 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.3 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 4.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 1.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.7 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.8 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 1.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0042245 RNA repair(GO:0042245)
0.0 1.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 4.6 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.8 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.3 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.7 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.4 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.9 GO:0006293 nucleotide-excision repair, preincision complex stabilization(GO:0006293)
0.0 1.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.8 GO:0044126 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.7 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.9 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 1.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 2.7 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 1.2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 2.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 1.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.9 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.8 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.9 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 1.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.8 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 1.2 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 1.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.6 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.6 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.3 0.9 GO:0034657 GID complex(GO:0034657)
0.2 2.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 1.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 0.6 GO:0097196 Shu complex(GO:0097196)
0.1 1.6 GO:0042382 paraspeckles(GO:0042382)
0.1 2.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.9 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 1.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.9 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.0 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.5 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 2.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.6 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.1 1.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.6 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.1 1.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 4.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 2.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.0 3.9 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.0 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.5 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 2.4 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.3 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 3.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 1.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.8 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.7 2.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.5 1.6 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.4 1.3 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.4 1.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.4 1.6 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.3 1.4 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.3 1.3 GO:0019862 IgA binding(GO:0019862)
0.2 1.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.2 0.7 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.2 1.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.2 0.9 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.2 1.4 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 2.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 3.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 0.8 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.2 0.4 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 3.9 GO:0043295 glutathione binding(GO:0043295)
0.2 0.7 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 2.9 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 2.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.5 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.1 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 1.5 GO:0031433 telethonin binding(GO:0031433)
0.1 1.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 1.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.8 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.7 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.5 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.3 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.8 GO:0008142 oxysterol binding(GO:0008142)
0.1 4.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.4 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.3 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 2.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.9 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0035197 siRNA binding(GO:0035197)
0.0 0.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 2.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 1.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.6 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 2.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 2.3 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.4 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 1.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.6 PID ATR PATHWAY ATR signaling pathway
0.0 1.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 1.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.1 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 5.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 1.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 2.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 2.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.5 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 3.2 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation