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Illumina Body Map 2

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Results for ZBTB16

Z-value: 0.96

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Transcription factors associated with ZBTB16

Gene Symbol Gene ID Gene Info
ENSG00000109906.9 zinc finger and BTB domain containing 16

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB16hg19_v2_chr11_+_113930291_113930339-0.715.4e-06Click!

Activity profile of ZBTB16 motif

Sorted Z-values of ZBTB16 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_48082192 4.53 ENST00000507351.1
TXK tyrosine kinase
chr6_-_49712123 4.08 ENST00000263045.4
cysteine-rich secretory protein 3
chr6_-_49712091 3.68 ENST00000371159.4
cysteine-rich secretory protein 3
chr12_-_53601055 3.08 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
integrin, beta 7
chr12_-_53601000 2.90 ENST00000338737.4
ENST00000549086.2
integrin, beta 7
chr5_-_55412774 2.74 ENST00000434982.2
ankyrin repeat domain 55
chr20_+_38633006 2.57 ENST00000432633.1
ENST00000445606.1
RP11-101E14.2
chr4_-_38784572 2.53 ENST00000308973.4
ENST00000361424.2
toll-like receptor 10
chr1_+_207277632 2.51 ENST00000421786.1
complement component 4 binding protein, alpha
chr4_-_38784592 2.48 ENST00000502321.1
toll-like receptor 10
chr7_-_38289173 2.48 ENST00000436911.2
T cell receptor gamma constant 2
chr1_+_198608292 2.29 ENST00000418674.1
protein tyrosine phosphatase, receptor type, C
chr1_+_198608146 2.13 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
protein tyrosine phosphatase, receptor type, C
chr2_+_89901292 2.11 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr6_-_49712147 2.10 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr3_-_120365866 2.05 ENST00000475447.2
homogentisate 1,2-dioxygenase
chr14_+_22670455 1.91 ENST00000390460.1
T cell receptor alpha variable 26-2
chr15_-_55562479 1.83 ENST00000564609.1
RAB27A, member RAS oncogene family
chr5_+_35856951 1.78 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
interleukin 7 receptor
chr14_+_22458631 1.76 ENST00000390444.1
T cell receptor alpha variable 16
chr4_+_74347400 1.75 ENST00000226355.3
afamin
chr2_+_204801471 1.73 ENST00000316386.6
ENST00000435193.1
inducible T-cell co-stimulator
chr19_+_14693888 1.73 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
C-type lectin domain family 17, member A
chr12_-_120765565 1.72 ENST00000423423.3
ENST00000308366.4
phospholipase A2, group IB (pancreas)
chr14_+_22564294 1.72 ENST00000390452.2
T cell receptor delta variable 1
chr15_-_55562582 1.69 ENST00000396307.2
RAB27A, member RAS oncogene family
chr2_-_89310012 1.68 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr10_+_90521163 1.66 ENST00000404459.1
lipase, family member N
chr12_+_10460549 1.66 ENST00000543420.1
ENST00000543777.1
killer cell lectin-like receptor subfamily D, member 1
chr6_-_49712072 1.64 ENST00000423399.2
cysteine-rich secretory protein 3
chr7_-_36764142 1.62 ENST00000258749.5
ENST00000535891.1
acyloxyacyl hydrolase (neutrophil)
chr6_-_44233361 1.60 ENST00000275015.5
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_+_45690646 1.54 ENST00000591569.1
Uncharacterized protein
chr4_+_36283213 1.51 ENST00000357504.3
death domain containing 1
chr3_+_46395219 1.50 ENST00000445132.2
ENST00000292301.4
chemokine (C-C motif) receptor 2
chr15_-_55562451 1.50 ENST00000568803.1
RAB27A, member RAS oncogene family
chr19_+_42041860 1.48 ENST00000483481.2
ENST00000494375.2
AC006129.4
chr12_+_21284118 1.48 ENST00000256958.2
solute carrier organic anion transporter family, member 1B1
chr7_-_36764004 1.46 ENST00000431169.1
acyloxyacyl hydrolase (neutrophil)
chr7_-_36764062 1.44 ENST00000435386.1
acyloxyacyl hydrolase (neutrophil)
chr9_-_116837249 1.40 ENST00000466610.2
alpha-1-microglobulin/bikunin precursor
chr7_+_76090993 1.38 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
deltex homolog 2 (Drosophila)
chr4_+_74606223 1.32 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr4_+_154622652 1.31 ENST00000260010.6
toll-like receptor 2
chr19_-_55150343 1.28 ENST00000456337.1
Uncharacterized protein
chr15_-_54051831 1.28 ENST00000557913.1
ENST00000360509.5
WD repeat domain 72
chr14_+_22788560 1.25 ENST00000390468.1
T cell receptor alpha variable 41
chr15_-_54025300 1.23 ENST00000559418.1
WD repeat domain 72
chr10_+_7745232 1.19 ENST00000358415.4
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_200011711 1.16 ENST00000544748.1
nuclear receptor subfamily 5, group A, member 2
chr10_+_7745303 1.16 ENST00000429820.1
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_12885183 1.13 ENST00000380659.3
toll-like receptor 7
chr19_+_42041702 1.09 ENST00000487420.2
AC006129.4
chr4_-_39033963 1.09 ENST00000381938.3
transmembrane protein 156
chr17_-_46623441 1.08 ENST00000330070.4
homeobox B2
chr12_+_4385230 1.06 ENST00000536537.1
cyclin D2
chr1_-_100231349 1.03 ENST00000287474.5
ENST00000414213.1
ferric-chelate reductase 1
chr16_+_81812863 1.02 ENST00000359376.3
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr12_+_20968608 1.00 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr10_-_10504285 0.98 ENST00000602311.1
RP11-271F18.4
chr2_+_90229045 0.97 ENST00000390278.2
immunoglobulin kappa variable 1D-42 (non-functional)
chr3_-_4927447 0.96 ENST00000449914.1
Uncharacterized protein
chr2_+_102618428 0.95 ENST00000457817.1
interleukin 1 receptor, type II
chr1_+_241695670 0.93 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_196857144 0.92 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
complement factor H-related 4
chr2_+_181988620 0.90 ENST00000428474.1
ENST00000424655.1
AC104820.2
chr19_+_42041537 0.88 ENST00000597199.1
AC006129.4
chr6_+_27925019 0.86 ENST00000244623.1
olfactory receptor, family 2, subfamily B, member 6
chr6_+_106988986 0.84 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr6_+_32812568 0.84 ENST00000414474.1
proteasome (prosome, macropain) subunit, beta type, 9
chr2_-_190448118 0.84 ENST00000440626.1
solute carrier family 40 (iron-regulated transporter), member 1
chr12_-_68696652 0.84 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr12_-_10007448 0.84 ENST00000538152.1
C-type lectin domain family 2, member B
chr12_-_113772835 0.83 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr9_-_71161505 0.82 ENST00000446290.1
RP11-274B18.2
chr15_-_50406680 0.81 ENST00000559829.1
ATPase, class I, type 8B, member 4
chr2_+_192543694 0.79 ENST00000435931.1
nucleic acid binding protein 1
chr2_-_61245363 0.79 ENST00000316752.6
pseudouridylate synthase 10
chr10_+_8096769 0.78 ENST00000346208.3
GATA binding protein 3
chr14_-_45722360 0.77 ENST00000451174.1
MIS18 binding protein 1
chr1_+_174769006 0.76 ENST00000489615.1
RAB GTPase activating protein 1-like
chr5_+_96212185 0.76 ENST00000379904.4
endoplasmic reticulum aminopeptidase 2
chr17_+_40925454 0.75 ENST00000253794.2
ENST00000590339.1
ENST00000589520.1
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr12_+_10460417 0.75 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
killer cell lectin-like receptor subfamily D, member 1
chr14_+_77228532 0.73 ENST00000167106.4
ENST00000554237.1
vasohibin 1
chr6_+_42749759 0.71 ENST00000314073.5
GLTSCR1-like
chr2_-_32490859 0.69 ENST00000404025.2
NLR family, CARD domain containing 4
chrX_+_115301975 0.68 ENST00000371906.4
angiotensin II receptor, type 2
chr6_+_136172820 0.63 ENST00000308191.6
phosphodiesterase 7B
chr11_-_327537 0.63 ENST00000602735.1
interferon induced transmembrane protein 3
chr19_+_3762645 0.61 ENST00000330133.4
mitochondrial ribosomal protein L54
chr10_+_48189612 0.61 ENST00000453919.1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 9
chr3_-_146262637 0.60 ENST00000472349.1
ENST00000342435.4
phospholipid scramblase 1
chr10_+_8096631 0.59 ENST00000379328.3
GATA binding protein 3
chr7_-_107770794 0.59 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
laminin, beta 4
chr5_+_180682720 0.59 ENST00000599439.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr11_-_104972158 0.58 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr8_-_30585439 0.58 ENST00000221130.5
glutathione reductase
chr16_+_19183671 0.57 ENST00000562711.2
synaptotagmin XVII
chr8_-_8318847 0.56 ENST00000521218.1
CTA-398F10.2
chr17_-_295730 0.56 ENST00000329099.4
family with sequence similarity 101, member B
chr20_-_54580523 0.56 ENST00000064571.2
cerebellin 4 precursor
chr3_-_93692781 0.56 ENST00000394236.3
protein S (alpha)
chr10_-_47239738 0.55 ENST00000413193.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 10
chr19_+_3762703 0.55 ENST00000589174.1
mitochondrial ribosomal protein L54
chr22_-_30901637 0.55 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14-like 4 (S. cerevisiae)
chr8_+_66619277 0.55 ENST00000521247.2
ENST00000527155.1
mitochondrial fission regulator 1
chr2_-_104496621 0.54 ENST00000455716.1
AC013727.1
chr4_-_88244010 0.54 ENST00000302219.6
hydroxysteroid (17-beta) dehydrogenase 13
chr19_-_56343353 0.54 ENST00000592953.1
ENST00000589093.1
NLR family, pyrin domain containing 11
chr14_+_22976633 0.53 ENST00000390503.1
T cell receptor alpha joining 34
chr5_-_54988448 0.53 ENST00000503817.1
ENST00000512595.1
solute carrier family 38, member 9
chr4_+_71263599 0.53 ENST00000399575.2
proline rich, lacrimal 1
chr4_-_76957214 0.52 ENST00000306621.3
chemokine (C-X-C motif) ligand 11
chr3_-_146262488 0.51 ENST00000487389.1
phospholipid scramblase 1
chr22_+_30821732 0.51 ENST00000355143.4
mitochondrial fission process 1
chr11_-_111649074 0.50 ENST00000534218.1
RP11-108O10.2
chr10_-_74283694 0.48 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
mitochondrial calcium uptake 1
chr6_+_26273144 0.47 ENST00000377733.2
histone cluster 1, H2bi
chr4_-_88244049 0.46 ENST00000328546.4
hydroxysteroid (17-beta) dehydrogenase 13
chr5_+_159848807 0.46 ENST00000352433.5
pituitary tumor-transforming 1
chr22_+_30821784 0.46 ENST00000407550.3
mitochondrial fission process 1
chr5_-_41071392 0.44 ENST00000399564.4
maestro heat-like repeat family member 2B
chr15_+_75628232 0.44 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr7_+_120591170 0.44 ENST00000431467.1
inhibitor of growth family, member 3
chr16_+_68071816 0.44 ENST00000562246.1
dihydrouridine synthase 2
chr8_-_48651648 0.42 ENST00000408965.3
CCAAT/enhancer binding protein (C/EBP), delta
chr13_-_101240985 0.42 ENST00000471912.1
gamma-glutamylamine cyclotransferase
chr17_-_37607497 0.41 ENST00000394287.3
ENST00000300651.6
mediator complex subunit 1
chr11_+_43380459 0.40 ENST00000299240.6
ENST00000039989.4
tetratricopeptide repeat domain 17
chr9_+_79074068 0.39 ENST00000444201.2
ENST00000376730.4
glucosaminyl (N-acetyl) transferase 1, core 2
chr19_+_45281118 0.39 ENST00000270279.3
ENST00000341505.4
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr19_-_23869999 0.37 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
zinc finger protein 675
chr6_+_25963020 0.36 ENST00000357085.3
tripartite motif containing 38
chr2_+_181988560 0.35 ENST00000424170.1
ENST00000435411.1
AC104820.2
chr16_+_22501658 0.35 ENST00000415833.2
nuclear pore complex interacting protein family, member B5
chr13_+_77564795 0.35 ENST00000377453.3
ceroid-lipofuscinosis, neuronal 5
chrX_-_2882296 0.35 ENST00000438544.1
ENST00000381134.3
ENST00000545496.1
arylsulfatase E (chondrodysplasia punctata 1)
chr8_+_104831472 0.35 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr12_+_105380073 0.35 ENST00000552951.1
ENST00000280749.5
chromosome 12 open reading frame 45
chr14_+_39703112 0.35 ENST00000555143.1
ENST00000280082.3
melanoma inhibitory activity 2
chr15_+_81391740 0.34 ENST00000561216.1
chromosome 15 open reading frame 26
chr11_-_66445219 0.34 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RNA binding motif protein 4B
chr11_-_111649015 0.34 ENST00000529841.1
RP11-108O10.2
chr12_+_133758115 0.34 ENST00000541009.2
ENST00000592241.1
zinc finger protein 268
chr1_+_247712383 0.34 ENST00000366488.4
ENST00000536561.1
germinal center-associated, signaling and motility-like
chr15_+_75628419 0.34 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMM domain containing 4
chr15_+_69365272 0.33 ENST00000559914.1
ENST00000558369.1
long intergenic non-protein coding RNA 277
chr4_+_37962018 0.33 ENST00000504686.1
pituitary tumor-transforming 2
chr21_-_16031122 0.33 ENST00000400562.1
Protein LOC388813
chr15_+_75628394 0.32 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr12_+_133657461 0.32 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
zinc finger protein 140
chr20_-_18477862 0.31 ENST00000337227.4
retinoblastoma binding protein 9
chr8_+_104831440 0.31 ENST00000515551.1
regulating synaptic membrane exocytosis 2
chr22_-_38239808 0.31 ENST00000406423.1
ENST00000424350.1
ENST00000458278.2
ankyrin repeat domain 54
chr4_-_140223670 0.30 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr11_-_64545222 0.29 ENST00000433274.2
ENST00000432725.1
splicing factor 1
chrX_-_47518527 0.29 ENST00000333119.3
ubiquitously-expressed, prefoldin-like chaperone
chr17_-_18266797 0.29 ENST00000316694.3
ENST00000539052.1
serine hydroxymethyltransferase 1 (soluble)
chr4_+_96012585 0.27 ENST00000502683.1
bone morphogenetic protein receptor, type IB
chr14_+_39703084 0.27 ENST00000553728.1
cTAGE family member 5 isoform 4
chr12_+_133757995 0.27 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
zinc finger protein 268
chr10_+_104614008 0.26 ENST00000369883.3
chromosome 10 open reading frame 32
chr22_+_29168652 0.26 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
coiled-coil domain containing 117
chr19_-_46195029 0.26 ENST00000588599.1
ENST00000585392.1
ENST00000590212.1
ENST00000587367.1
ENST00000391932.3
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr7_-_104909435 0.26 ENST00000357311.3
SRSF protein kinase 2
chr12_-_7656357 0.26 ENST00000396620.3
ENST00000432237.2
ENST00000359156.4
CD163 molecule
chr12_-_25150409 0.25 ENST00000549262.1
chromosome 12 open reading frame 77
chr7_+_106505912 0.25 ENST00000359195.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr7_-_38313235 0.25 ENST00000390338.2
T cell receptor gamma joining P
chr18_-_21017817 0.24 ENST00000542162.1
ENST00000383233.3
ENST00000582336.1
ENST00000450466.2
ENST00000578520.1
ENST00000399707.1
transmembrane protein 241
chr16_-_46649905 0.24 ENST00000569702.1
SHC SH2-domain binding protein 1
chr9_+_131901710 0.24 ENST00000524946.2
protein phosphatase 2A activator, regulatory subunit 4
chr5_+_115387163 0.24 ENST00000601302.2
ADP-ribosylation factor-like 14 effector protein-like
chr7_-_92777606 0.24 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
sterile alpha motif domain containing 9-like
chr11_+_5009424 0.24 ENST00000300762.1
matrix metallopeptidase 26
chr4_-_83769996 0.23 ENST00000511338.1
SEC31 homolog A (S. cerevisiae)
chr3_-_15382875 0.23 ENST00000408919.3
SH3-domain binding protein 5 (BTK-associated)
chr5_+_72509751 0.23 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
chr4_+_95128748 0.23 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr6_+_74171301 0.23 ENST00000415954.2
ENST00000498286.1
ENST00000370305.1
ENST00000370300.4
mitochondrial tRNA translation optimization 1
chr1_+_12916941 0.22 ENST00000240189.2
PRAME family member 2
chr8_-_37797621 0.22 ENST00000524298.1
ENST00000307599.4
glutamic-oxaloacetic transaminase 1-like 1
chr10_+_104613980 0.22 ENST00000339834.5
chromosome 10 open reading frame 32
chr15_-_85197501 0.22 ENST00000434634.2
WD repeat domain 73
chr6_-_138893661 0.22 ENST00000427025.2
NHS-like 1
chr12_+_58166726 0.22 ENST00000546504.1
Uncharacterized protein
chr11_+_120255997 0.21 ENST00000532993.1
Rho guanine nucleotide exchange factor (GEF) 12
chr9_-_106087316 0.21 ENST00000411575.1
RP11-341A22.2
chr17_-_39341594 0.21 ENST00000398472.1
keratin associated protein 4-1
chr14_+_22951276 0.21 ENST00000390484.1
T cell receptor alpha joining 54
chr15_-_34880646 0.21 ENST00000543376.1
golgin A8 family, member A
chr5_+_68860949 0.21 ENST00000507595.1
general transcription factor IIH, polypeptide 2C
chr10_-_45802907 0.20 ENST00000374401.2
olfactory receptor, family 13, subfamily A, member 1
chr12_-_75905374 0.20 ENST00000438169.2
ENST00000229214.4
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr4_+_158493642 0.20 ENST00000507108.1
ENST00000455598.1
ENST00000509450.1
RP11-364P22.1
chr10_+_134258649 0.20 ENST00000392630.3
ENST00000321248.2
chromosome 10 open reading frame 91
chr10_+_118083919 0.19 ENST00000333254.3
coiled-coil domain containing 172
chr12_+_50690489 0.19 ENST00000598429.1
Uncharacterized protein
chr1_+_149239529 0.19 ENST00000457216.2
RP11-403I13.4

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB16

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.2 5.9 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.7 5.0 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.7 4.9 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.4 1.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.4 1.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.3 1.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.3 1.4 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 1.1 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.3 0.8 GO:1903988 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.3 1.0 GO:0002316 follicular B cell differentiation(GO:0002316)
0.3 2.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 0.9 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.2 2.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.7 GO:0035566 negative regulation of icosanoid secretion(GO:0032304) regulation of metanephros size(GO:0035566)
0.2 0.6 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.7 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.2 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 0.6 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.1 0.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 1.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.6 GO:0042940 D-amino acid transport(GO:0042940)
0.1 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 2.5 GO:0070166 enamel mineralization(GO:0070166)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 1.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.7 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 0.4 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.1 1.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.7 GO:0070269 pyroptosis(GO:0070269)
0.1 0.2 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.8 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.1 5.0 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.8 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.8 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.8 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 1.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.5 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.6 GO:0009306 protein secretion(GO:0009306)
0.0 0.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 1.0 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.6 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 1.0 GO:0014850 response to muscle activity(GO:0014850)
0.0 2.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.4 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 1.7 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 2.4 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.1 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 1.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 3.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.9 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.2 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 11.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.3 1.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.3 5.0 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 0.8 GO:0000814 ESCRT II complex(GO:0000814)
0.1 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 11.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 0.8 GO:0070876 SOSS complex(GO:0070876)
0.1 1.1 GO:0032009 early phagosome(GO:0032009)
0.1 0.8 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.8 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 7.9 GO:0072562 blood microparticle(GO:0072562)
0.0 11.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.4 1.8 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 1.7 GO:0008431 vitamin E binding(GO:0008431)
0.4 2.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.3 1.4 GO:0019862 IgA binding(GO:0019862)
0.3 0.8 GO:0097689 iron channel activity(GO:0097689)
0.2 1.7 GO:0042806 fucose binding(GO:0042806)
0.2 1.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 0.9 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2 1.4 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 1.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.2 1.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 5.0 GO:0031489 myosin V binding(GO:0031489)
0.1 1.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.6 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 1.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.1 GO:0035197 siRNA binding(GO:0035197)
0.1 0.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.4 GO:0070905 serine binding(GO:0070905)
0.1 0.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 1.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.0 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 5.6 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 4.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 2.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.8 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.0 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 5.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 2.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.6 ST GAQ PATHWAY G alpha q Pathway
0.0 1.6 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 2.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 5.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.7 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 8.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.4 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 2.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.9 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 4.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 1.7 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA