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Illumina Body Map 2

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Results for ZBTB3

Z-value: 0.98

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Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ENSG00000185670.7 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_625216600.232.1e-01Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41122063 4.10 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
triggering receptor expressed on myeloid cells-like 1
chr3_-_39322728 4.07 ENST00000541347.1
ENST00000412814.1
chemokine (C-X3-C motif) receptor 1
chr12_-_62586543 3.61 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr6_+_123100620 3.13 ENST00000368444.3
fatty acid binding protein 7, brain
chr4_+_159122728 2.93 ENST00000505049.1
ENST00000505189.1
ENST00000511038.1
transmembrane protein 144
chr6_+_12958137 2.89 ENST00000457702.2
ENST00000379345.2
phosphatase and actin regulator 1
chr18_+_32073253 2.78 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
dystrobrevin, alpha
chrX_+_152224766 2.67 ENST00000370265.4
ENST00000447306.1
paraneoplastic Ma antigen 3
chr5_-_82969405 2.55 ENST00000510978.1
hyaluronan and proteoglycan link protein 1
chr21_-_48024986 2.32 ENST00000291700.4
ENST00000367071.4
S100 calcium binding protein B
chr5_-_149669612 2.25 ENST00000510347.1
calcium/calmodulin-dependent protein kinase II alpha
chr16_+_24266874 2.25 ENST00000005284.3
calcium channel, voltage-dependent, gamma subunit 3
chr1_-_111148969 2.01 ENST00000316361.4
potassium voltage-gated channel, shaker-related subfamily, member 2
chrX_+_70364667 1.95 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
neuroligin 3
chr12_+_48577366 1.86 ENST00000316554.3
chromosome 12 open reading frame 68
chr19_-_19006920 1.83 ENST00000429504.2
ENST00000427170.2
ceramide synthase 1
chr6_+_30850697 1.82 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
discoidin domain receptor tyrosine kinase 1
chr16_+_87636474 1.80 ENST00000284262.2
junctophilin 3
chr19_-_19006890 1.80 ENST00000247005.6
growth differentiation factor 1
chr14_+_32964258 1.79 ENST00000556638.1
A kinase (PRKA) anchor protein 6
chr3_-_149688971 1.72 ENST00000498307.1
ENST00000489155.1
profilin 2
chr1_-_111148241 1.72 ENST00000440270.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr6_+_30850862 1.71 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
discoidin domain receptor tyrosine kinase 1
chr16_-_19896150 1.54 ENST00000570142.1
G protein-coupled receptor, family C, group 5, member B
chr3_+_98250743 1.50 ENST00000284311.3
G protein-coupled receptor 15
chr5_+_75378997 1.42 ENST00000502798.2
synaptic vesicle glycoprotein 2C
chr6_+_123100853 1.40 ENST00000356535.4
fatty acid binding protein 7, brain
chr11_+_26353664 1.35 ENST00000531646.1
anoctamin 3
chr5_+_112074029 1.32 ENST00000512211.2
adenomatous polyposis coli
chr2_-_40679148 1.27 ENST00000417271.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_+_138609441 1.27 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr17_-_17109579 1.14 ENST00000321560.3
phospholipase D family, member 6
chr7_+_100081542 1.13 ENST00000300179.2
ENST00000423930.1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr8_+_38261880 1.13 ENST00000527175.1
leucine zipper-EF-hand containing transmembrane protein 2
chr13_-_48612067 1.13 ENST00000543413.1
succinate-CoA ligase, ADP-forming, beta subunit
chr2_-_40679186 1.10 ENST00000406785.2
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_-_94417339 1.10 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
multiple C2 domains, transmembrane 1
chr1_+_160160346 1.10 ENST00000368078.3
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_+_75542997 1.09 ENST00000592651.1
ENST00000590398.1
RP11-13K12.1
chr5_-_94417186 1.08 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr1_+_159141397 1.08 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
cell adhesion molecule 3
chr14_+_22538811 1.05 ENST00000390450.3
T cell receptor alpha variable 22
chr1_+_160121356 1.04 ENST00000368081.4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr10_-_73533255 1.01 ENST00000394957.3
chromosome 10 open reading frame 54
chr19_-_40023450 1.00 ENST00000326282.4
EP300 interacting inhibitor of differentiation 2B
chr3_-_149688502 1.00 ENST00000481767.1
ENST00000475518.1
profilin 2
chr5_-_94417314 0.99 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr16_+_30034655 0.98 ENST00000300575.2
chromosome 16 open reading frame 92
chr5_-_94417562 0.97 ENST00000505465.1
multiple C2 domains, transmembrane 1
chr1_+_155146318 0.94 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
tripartite motif containing 46
chr16_-_68406161 0.94 ENST00000568373.1
ENST00000563226.1
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr11_-_82782952 0.89 ENST00000534141.1
RAB30, member RAS oncogene family
chr3_-_149688896 0.86 ENST00000239940.7
profilin 2
chr19_-_49496557 0.85 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
glycogen synthase 1 (muscle)
chr16_-_19896220 0.84 ENST00000562469.1
ENST00000300571.2
G protein-coupled receptor, family C, group 5, member B
chr9_+_72002837 0.77 ENST00000377216.3
family with sequence similarity 189, member A2
chr11_-_82782861 0.75 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30, member RAS oncogene family
chr7_-_38403077 0.75 ENST00000426402.2
T cell receptor gamma variable 2
chr4_-_5894777 0.74 ENST00000324989.7
collapsin response mediator protein 1
chr1_-_236046872 0.74 ENST00000536965.1
lysosomal trafficking regulator
chr4_+_2626988 0.74 ENST00000509050.1
family with sequence similarity 193, member A
chr1_-_169555709 0.73 ENST00000546081.1
coagulation factor V (proaccelerin, labile factor)
chr12_-_114843889 0.72 ENST00000405440.2
T-box 5
chr10_-_76868931 0.70 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
dual specificity phosphatase 13
chr20_+_54987168 0.69 ENST00000360314.3
Cas scaffolding protein family member 4
chr8_+_144718171 0.69 ENST00000526926.1
ENST00000458270.2
zinc finger protein 623
chr3_-_149688655 0.67 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
profilin 2
chr12_-_120241187 0.66 ENST00000392520.2
citron (rho-interacting, serine/threonine kinase 21)
chr6_-_46138676 0.63 ENST00000371383.2
ENST00000230565.3
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr11_+_64692143 0.63 ENST00000164133.2
ENST00000532850.1
protein phosphatase 2, regulatory subunit B', beta
chr1_+_110036674 0.62 ENST00000393709.3
cytochrome b561 family, member D1
chrX_-_152245978 0.62 ENST00000538162.2
paraneoplastic Ma antigen family member 6D (pseudogene)
chr8_-_42623747 0.61 ENST00000534622.1
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr17_+_75123947 0.61 ENST00000586429.1
SEC14-like 1 (S. cerevisiae)
chr20_+_54987305 0.59 ENST00000371336.3
ENST00000434344.1
Cas scaffolding protein family member 4
chr3_-_195163584 0.58 ENST00000439666.1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chrX_+_134166333 0.57 ENST00000257013.7
family with sequence similarity 127, member A
chr8_-_42623924 0.57 ENST00000276410.2
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr10_-_76868866 0.56 ENST00000607487.1
dual specificity phosphatase 13
chr19_+_39926791 0.50 ENST00000594990.1
suppressor of Ty 5 homolog (S. cerevisiae)
chr1_-_204463829 0.50 ENST00000429009.1
ENST00000415899.1
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr19_-_55549624 0.50 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
glycoprotein VI (platelet)
chr5_-_82969363 0.48 ENST00000503117.1
hyaluronan and proteoglycan link protein 1
chr1_+_110036699 0.48 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
cytochrome b561 family, member D1
chr5_-_169725231 0.45 ENST00000046794.5
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_12040238 0.44 ENST00000444836.1
ENST00000235329.5
mitofusin 2
chr3_-_195163803 0.43 ENST00000326793.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_+_65210772 0.42 ENST00000371072.4
ENST00000294428.3
ribonucleoprotein, PTB-binding 2
chr1_-_169555779 0.42 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr10_+_99332198 0.39 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ankyrin repeat domain 2 (stretch responsive muscle)
chrX_-_152343394 0.38 ENST00000370261.1
paraneoplastic Ma antigen family member 6B (pseudogene)
chr11_-_130786333 0.38 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
sorting nexin 19
chr4_-_7436671 0.37 ENST00000319098.4
prosaposin-like 1 (gene/pseudogene)
chr19_+_52848659 0.37 ENST00000327920.8
zinc finger protein 610
chr7_-_38394118 0.37 ENST00000390345.2
T cell receptor gamma variable 4
chr6_+_42141029 0.35 ENST00000372958.1
guanylate cyclase activator 1A (retina)
chr6_+_30851205 0.33 ENST00000515881.1
discoidin domain receptor tyrosine kinase 1
chrX_+_118708517 0.33 ENST00000346330.3
ubiquitin-conjugating enzyme E2A
chr9_+_74526384 0.33 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr5_+_75379224 0.33 ENST00000322285.7
synaptic vesicle glycoprotein 2C
chr3_-_49131614 0.32 ENST00000450685.1
glutamine-rich 1
chrX_+_152240819 0.31 ENST00000421798.3
ENST00000535416.1
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr5_-_74807418 0.30 ENST00000405807.4
ENST00000261415.7
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_-_25565377 0.29 ENST00000264709.3
ENST00000406659.3
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_-_130786400 0.27 ENST00000265909.4
sorting nexin 19
chr2_-_154335300 0.27 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr9_+_125132803 0.27 ENST00000540753.1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr20_-_62203808 0.26 ENST00000467148.1
helicase with zinc finger 2, transcriptional coactivator
chrX_-_118827333 0.25 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
septin 6
chr1_+_110036728 0.25 ENST00000369868.3
ENST00000430195.2
cytochrome b561 family, member D1
chr7_-_127225620 0.25 ENST00000321407.2
GRIP and coiled-coil domain containing 1
chr18_-_33709268 0.25 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
solute carrier family 39 (zinc transporter), member 6
chrX_+_118708493 0.24 ENST00000371558.2
ubiquitin-conjugating enzyme E2A
chr4_+_159236462 0.23 ENST00000460056.2
relaxin/insulin-like family peptide receptor 1
chr5_+_74807886 0.21 ENST00000514296.1
polymerase (DNA directed) kappa
chr3_-_49131788 0.19 ENST00000395443.2
ENST00000411682.1
glutamine-rich 1
chrX_+_152338301 0.18 ENST00000453825.2
paraneoplastic Ma antigen family member 6A
chr5_+_140514782 0.16 ENST00000231134.5
protocadherin beta 5
chr2_-_136594740 0.16 ENST00000264162.2
lactase
chr1_-_32801825 0.14 ENST00000329421.7
MARCKS-like 1
chr9_+_74526532 0.14 ENST00000486911.2
chromosome 9 open reading frame 85
chr17_+_33895090 0.13 ENST00000592381.1
RP11-1094M14.11
chr1_-_149908710 0.11 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
myotubularin related protein 11
chr4_+_48492269 0.10 ENST00000327939.4
zygote arrest 1
chr12_+_8185288 0.10 ENST00000162391.3
forkhead box J2
chr16_+_89787393 0.10 ENST00000289816.5
ENST00000568064.1
zinc finger protein 276
chr3_-_49131473 0.09 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
glutamine-rich 1
chr2_+_241631262 0.09 ENST00000337801.4
ENST00000429564.1
aquaporin 12A
chr15_-_74659978 0.07 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
cytochrome P450, family 11, subfamily A, polypeptide 1
chr7_+_23719749 0.06 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
family with sequence similarity 221, member A
chr12_+_123949053 0.06 ENST00000350887.5
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr8_+_42196000 0.04 ENST00000518925.1
ENST00000538005.1
polymerase (DNA directed), beta
chr3_+_178276488 0.02 ENST00000432997.1
ENST00000455865.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_+_210001309 0.01 ENST00000491415.2
digestive organ expansion factor homolog (zebrafish)
chrX_+_11776278 0.01 ENST00000312196.4
ENST00000337339.2
male-specific lethal 3 homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.6 3.7 GO:0021633 optic nerve structural organization(GO:0021633)
0.6 1.8 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.4 2.0 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 4.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 1.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 0.7 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.7 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.2 1.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 1.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 2.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 3.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.2 GO:0032571 response to vitamin K(GO:0032571)
0.2 2.3 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.2 0.7 GO:1990502 dense core granule maturation(GO:1990502)
0.2 4.5 GO:0060134 prepulse inhibition(GO:0060134)
0.1 1.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 2.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 2.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 2.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 4.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.9 GO:0099612 protein localization to axon(GO:0099612)
0.0 2.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.8 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 1.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 1.0 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 1.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 2.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 5.0 GO:0030168 platelet activation(GO:0030168)
0.0 3.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0072678 T cell migration(GO:0072678)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 GO:0033010 paranodal junction(GO:0033010)
0.2 3.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.1 GO:0014802 terminal cisterna(GO:0014802)
0.2 0.9 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.5 GO:0036398 TCR signalosome(GO:0036398)
0.1 4.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.3 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.5 GO:0032044 DSIF complex(GO:0032044)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.0 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 4.3 GO:0043195 terminal bouton(GO:0043195)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 5.3 GO:0031091 platelet alpha granule(GO:0031091)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 2.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.3 2.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 3.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 3.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0039552 RIG-I binding(GO:0039552)
0.1 2.3 GO:0050786 tau protein binding(GO:0048156) RAGE receptor binding(GO:0050786)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 4.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.8 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 4.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 2.9 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 1.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism