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Illumina Body Map 2
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Results for ZBTB33_CHD2
Z-value: 2.36
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Transcription factors associated with ZBTB33_CHD2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CHD2 | hg19_v2_chr15_+_93426514_93426562 | -0.43 | 1.5e-02 | Click! |
| ZBTB33 | hg19_v2_chrX_+_119384607_119384720 | 0.02 | 9.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_78730531 Show fit | 5.72 |
ENST00000258886.8
|
iron-responsive element binding protein 2 |
|
| chr1_+_232940643 Show fit | 5.50 |
ENST00000418460.1
|
microtubule-associated protein 10 |
|
| chr1_-_111991850 Show fit | 5.14 |
ENST00000411751.2
|
WD repeat domain 77 |
|
| chr15_+_78730622 Show fit | 4.92 |
ENST00000560440.1
|
iron-responsive element binding protein 2 |
|
| chrX_-_53711064 Show fit | 4.42 |
ENST00000342160.3
ENST00000446750.1 |
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
|
| chrY_+_15016725 Show fit | 4.40 |
ENST00000336079.3
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
|
| chr1_-_111991908 Show fit | 4.22 |
ENST00000235090.5
|
WD repeat domain 77 |
|
| chr10_+_51565188 Show fit | 4.09 |
ENST00000430396.2
ENST00000374087.4 ENST00000414907.2 |
nuclear receptor coactivator 4 |
|
| chr6_+_35995552 Show fit | 3.97 |
ENST00000468133.1
|
mitogen-activated protein kinase 14 |
|
| chr10_+_51565108 Show fit | 3.89 |
ENST00000438493.1
ENST00000452682.1 |
nuclear receptor coactivator 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZBTB33_CHD2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 22.9 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 2.3 | 11.3 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.1 | 10.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 1.6 | 9.4 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 0.3 | 8.9 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.1 | 8.5 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.0 | 6.6 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.3 | 5.5 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.8 | 5.4 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.1 | 5.3 | GO:0005980 | glycogen catabolic process(GO:0005980) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 22.7 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 22.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 14.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 13.7 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.1 | 10.7 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.4 | 8.9 | GO:0034709 | methylosome(GO:0034709) |
| 0.0 | 8.3 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 7.7 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.4 | 7.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 7.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.9 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.1 | 14.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 12.5 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.9 | 11.4 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 3.5 | 10.6 | GO:0030350 | iron-responsive element binding(GO:0030350) |
| 0.5 | 10.1 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.2 | 9.6 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.3 | 8.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 8.4 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 7.1 | GO:0050681 | androgen receptor binding(GO:0050681) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 17.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 16.5 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.3 | 13.3 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 12.0 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 5.5 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 4.0 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 3.9 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 3.8 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.6 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 3.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 21.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 14.6 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 13.3 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.5 | 11.3 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.4 | 8.5 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.1 | 7.9 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.2 | 7.2 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 6.6 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 6.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.2 | 6.1 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |